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4,488 Results Found

  • Review
  • Open Access
20 Citations
9,896 Views
34 Pages

Non-Conventional Risk Factors: “Fact” or “Fake” in Cardiovascular Disease Prevention?

  • Giovanni Cimmino,
  • Francesco Natale,
  • Roberta Alfieri,
  • Luigi Cante,
  • Simona Covino,
  • Rosa Franzese,
  • Mirella Limatola,
  • Luigi Marotta,
  • Riccardo Molinari and
  • Paolo Golino
  • + 2 authors

Cardiovascular diseases (CVDs), such as arterial hypertension, myocardial infarction, stroke, heart failure, atrial fibrillation, etc., still represent the main cause of morbidity and mortality worldwide. They significantly modify the patients’...

  • Article
  • Open Access
17 Citations
5,123 Views
11 Pages

Adherence to European Clinical Practice Guidelines for Secondary Prevention of Cardiovascular Disease: A Cohort Study

  • Josep Maria Pepió Vilaubí,
  • Domingo Orozco-Beltrán,
  • Alessandra Queiroga Gonçalves,
  • Dolors Rodriguez Cumplido,
  • Carina Aguilar Martin,
  • Adriana Lopez-Pineda,
  • Vicente F. Gil-Guillen,
  • Jose A. Quesada and
  • Concepcion Carratala-Munuera

To provide a better understanding of the actions taken within health systems and their results, this study aims to assess clinicians’ adherence to clinical practice guidelines (CPGs) regarding recommended treatments in patients with cardiovascular di...

  • Perspective
  • Open Access
2,411 Views
23 Pages

13 October 2025

Residual cardiovascular risk remains substantial despite widespread adoption of intensive lipid-lowering strategies—statins, PCSK9 inhibitors, and RNA-based agents—that achieve very low LDL-C and apoB levels. Over the past three years, co...

  • Article
  • Open Access
8 Citations
9,503 Views
4 Pages

Implementation of a Cardiovascular Disease Prevention Program among School-Aged Children: A Pilot Study

  • Clifton C. Addison,
  • Brenda W. Jenkins,
  • Monique S. White and
  • Lavon Young

The objective of this study was to test students’ knowledge of cardiovascular disease information and to determine if a carefully structured training program administered to high school students would increase their knowledge about cardiovascular dis...

  • Review
  • Open Access
3 Citations
3,628 Views
16 Pages

Active Commuting as a Factor of Cardiovascular Disease Prevention: A Systematic Review with Meta-Analysis

  • Claudia Baran,
  • Shanice Belgacem,
  • Mathilde Paillet,
  • Raphael Martins de Abreu,
  • Francisco Xavier de Araujo,
  • Roberto Meroni and
  • Camilo Corbellini

Active commuting (AC) may have the potential to prevent the incidence of cardiovascular disease (CVD). However, the evidence for a correlation between AC and the risk of CVD remains uncertain. The current study thoroughly and qualitatively summarized...

  • Review
  • Open Access
26 Citations
10,574 Views
12 Pages

Chlamydia pneumoniae and Oxidative Stress in Cardiovascular Disease: State of the Art and Prevention Strategies

  • Marisa Di Pietro,
  • Simone Filardo,
  • Fiorenzo De Santis,
  • Paola Mastromarino and
  • Rosa Sessa

30 December 2014

Chlamydia pneumoniae, a pathogenic bacteria responsible for respiratory tract infections, is known as the most implicated infectious agent in atherosclerotic cardiovascular diseases (CVDs). Accumulating evidence suggests that C. pneumoniae-induced ox...

  • Review
  • Open Access
53 Citations
14,916 Views
15 Pages

27 June 2022

The development of cardiovascular diseases is undoubtedly influenced by improper dietary behavior. The most common mistakes include irregularity of meal consumption, high dietary atherogenicity: snacking on sweets between meals, low supply of dietary...

  • Article
  • Open Access
4 Citations
3,020 Views
12 Pages

Cardiovascular Disease-Related Health Promotion and Prevention Services by Pharmacists in Saudi Arabia: How Well Are They Prepared?

  • Sirajudeen Shaik Alavudeen,
  • Vigneshwaran Easwaran,
  • Noohu Abdulla Khan,
  • Krishnaraju Venkatesan,
  • Premalatha Paulsamy,
  • Abubakr Taha Mohammed Hussein,
  • Mohammad Tarique Imam,
  • Ziyad Saeed Almalki and
  • Md Sayeed Akhtar

Background: Cardiovascular diseases (CVDs) have been identified as the leading reason for morbidity and mortality in Saudi Arabia. Pharmacists play a major role in CVD prevention and health promotion. We aimed to assess the knowledge, attitudes, and...

  • Article
  • Open Access
6 Citations
2,432 Views
17 Pages

Barriers and Facilitators to Cardiovascular Disease Prevention Following Hypertensive Disorders of Pregnancy in Primary Care: Cross-Sectional Surveys

  • Kaylee Slater,
  • Rachael Taylor,
  • Karen McLaughlin,
  • Craig Pennell,
  • Clare Collins and
  • Melinda Hutchesson

31 August 2023

Women with a history of hypertensive disorders of pregnancy (HDP) have an increased risk of cardiovascular disease (CVD). Guidelines recommend that women diagnosed with HDP should be advised of their increased CVD risk, have regular blood pressure mo...

  • Article
  • Open Access
2 Citations
2,982 Views
10 Pages

Effectiveness of Statins for Primary Prevention of Cardiovascular Disease in Low- and Medium-Risk Males: A Causal Inference Approach with Observational Data

  • Armando Chaure-Pardos,
  • Isabel Aguilar-Palacio,
  • Mª José Rabanaque,
  • Mª Jesús Lallana,
  • Lina Maldonado,
  • Sara Castel-Feced,
  • Julián Librero,
  • José Antonio Casasnovas and
  • Sara Malo

20 April 2022

In this study, we analyzed the effectiveness of statin therapy for the primary prevention of cardiovascular disease (CVD) in low- and medium-risk patients. Using observational data, we estimated effectiveness by emulating a hypothetical randomized cl...

  • Review
  • Open Access
9 Citations
10,122 Views
19 Pages

Background: High-intensity interval training (HIIT) has gained recognition for its positive impacts on cardiovascular (CV) health, metabolic outcomes, mental health, and quality of life (QoL). This narrative review aims to comprehensively evaluate th...

  • Article
  • Open Access
1,280 Views
14 Pages

Increased Walking Speed Reduces Hospitalization Rates in Patients with Cardiovascular Disease During Exercise-Based Secondary Prevention

  • Andrea Raisi,
  • Tommaso Piva,
  • Jonathan Myers,
  • Valentina Zerbini,
  • Erica Menegatti,
  • Margherita Lembo,
  • Sofia Michelon,
  • Isabella Meneghini,
  • Giovanni Grazzi and
  • Simona Mandini
  • + 1 author

27 June 2025

Background/Objectives: Walking speed (WS) is associated with morbidity and mortality. This study sought to investigate the associations between WS and hospitalization among patients with stable cardiovascular disease (CVD) and analyze how changes in...

  • Article
  • Open Access
3,703 Views
13 Pages

A 10-Year Risk Assessment and Primary Prevention Study of Atherosclerotic Cardiovascular Disease Among Adult Patients in Saudi Arabia: A Cross-Sectional Study

  • Abdulhameed Alkhalaf,
  • Qasem Aljabr,
  • Khalid Al Mulla,
  • Duaa Almubarak,
  • Abdul Sattar Khan,
  • Zainab Y. Al Jaziri and
  • Ibrahim Albahrani

15 January 2025

Background and Objectives: Cardiovascular diseases (CVDs), primarily driven by atherosclerosis, are the leading cause of mortality worldwide. In Saudi Arabia, the prevalence of atherosclerotic cardiovascular disease (ASCVD) poses a significant public...

  • Article
  • Open Access
12 Citations
4,279 Views
14 Pages

29 November 2022

(1) Background: Hypertensive patients with obstructive sleep apnea (OSA) are at high risk for cardiovascular diseases (CVDs), and the utility of aspirin for primary cardiovascular prevention in this population remains uncertain. (2) Methods: In this...

  • Article
  • Open Access
3 Citations
3,365 Views
10 Pages

Decision Support Tools for Coronary Artery Calcium Scoring in the Primary Prevention of Cardiovascular Disease Do Not Meet Health Literacy Needs: A Systematic Environmental Scan and Evaluation

  • Shannon McKinn,
  • Carys Batcup,
  • Samuel Cornell,
  • Natasha Freeman,
  • Jenny Doust,
  • Katy J. L. Bell,
  • Gemma A. Figtree and
  • Carissa Bonner

A shared decision-making approach is considered optimal in primary cardiovascular disease (CVD) prevention. Evidence-based patient decision aids can facilitate this but do not always meet patients’ health literacy needs. Coronary artery calcium...

  • Review
  • Open Access
140 Citations
27,515 Views
23 Pages

Lycopene in the Prevention of Cardiovascular Diseases

  • Sylwia Przybylska and
  • Grzegorz Tokarczyk

10 February 2022

Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide. Oxidative stress and inflammation are pathophysiological processes involved in the development of CVD. That is why bioactive food ingredients, including lycopene, are...

  • Review
  • Open Access
166 Citations
34,522 Views
16 Pages

Cardiovascular Risk Factors and Physical Activity for the Prevention of Cardiovascular Diseases in the Elderly

  • Lorena Ciumărnean,
  • Mircea Vasile Milaciu,
  • Vasile Negrean,
  • Olga Hilda Orășan,
  • Stefan Cristian Vesa,
  • Octavia Sălăgean,
  • Silvina Iluţ and
  • Sonia Irina Vlaicu

Cardiovascular diseases create an important burden on the public health systems, especially in the elderly, mostly because this group of patients frequently suffer from multiple comorbidities. Accumulating cardiovascular risk factors during their lif...

  • Article
  • Open Access
17 Citations
6,656 Views
17 Pages

Objectives: To assess the cost-effectiveness of workplace-delivered interventions designed to reduce sitting time as primary prevention measures for cardiovascular disease (CVD) in Australia. Methods: A Markov model was developed to simulate the life...

  • Review
  • Open Access
91 Citations
18,817 Views
46 Pages

Lifestyle interventions (i.e., diet and/or physical activity) are effective in delaying or preventing the onset of diabetes and cardiovascular disease. However, policymakers must know the cost-effectiveness of such interventions before implementing t...

  • Article
  • Open Access
3 Citations
2,440 Views
9 Pages

4 June 2024

Background: Cardiovascular diseases are the most frequent cause of death worldwide. The aim of this study was to identify and demonstrate correlations between mortality data and etiological factors in EU countries. The relationships presented could t...

  • Review
  • Open Access
13 Citations
5,210 Views
20 Pages

The Legacy Effect in the Prevention of Cardiovascular Disease

  • Esther Viñas Esmel,
  • José Naval Álvarez and
  • Emilio Sacanella Meseguer

22 October 2020

The “legacy effect” describes the long-term benefits that may persist for many years after the end of an intervention period, involving different biological processes. The legacy effect in cardiovascular disease (CVD) prevention has been...

  • Systematic Review
  • Open Access
65 Citations
24,053 Views
16 Pages

Mediterranean Diet for Primary and Secondary Prevention of Cardiovascular Disease and Mortality: An Updated Systematic Review

  • Ana Laffond,
  • Cristina Rivera-Picón,
  • Pedro Manuel Rodríguez-Muñoz,
  • Raúl Juárez-Vela,
  • Regina Ruiz de Viñaspre-Hernández,
  • Noelia Navas-Echazarreta and
  • Juan Luis Sánchez-González

28 July 2023

Cardiovascular diseases (CVDs) are currently the leading cause of mortality worldwide, with coronary heart disease being the primary cause. The Mediterranean Diet (MD) has been highlighted for its potential in providing greater protection against CVD...

  • Review
  • Open Access
8 Citations
10,998 Views
20 Pages

The Efficacy of Vitamins in the Prevention and Treatment of Cardiovascular Disease

  • Paramjit S. Tappia,
  • Anureet K. Shah and
  • Naranjan S. Dhalla

10 September 2024

Vitamins are known to affect the regulation of several biochemical and metabolic pathways that influence cellular function. Adequate amounts of both hydrophilic and lipophilic vitamins are required for maintaining normal cardiac and vascular function...

  • Review
  • Open Access
143 Citations
16,880 Views
17 Pages

31 October 2020

Obesity is one of the major risk factors for the development of both impaired glucose tolerance (IGT, or prediabetes) and type 2 diabetes (T2D), and its prevalence worldwide drives toward an increased rate of cardiovascular morbidity and mortality. G...

  • Review
  • Open Access
12 Citations
5,718 Views
14 Pages

Non-Invasive Imaging Assessment in Patients with Aortic Coarctation: A Contemporary Review

  • Isabella Leo,
  • Jolanda Sabatino,
  • Martina Avesani,
  • Sara Moscatelli,
  • Francesco Bianco,
  • Nunzia Borrelli,
  • Rosalba De Sarro,
  • Benedetta Leonardi,
  • Giuseppe Calcaterra and
  • on behalf of the Working Group on Congenital Heart Disease, Cardiovascular Prevention in Paediatric Age of the Italian Society of Cardiology (SIC)
  • + 2 authors

20 December 2023

Coarctation of the aorta (CoA) is a congenital abnormality characterized by a narrowing of the aortic lumen, which can lead to significant morbidity and mortality if left untreated. Even after repair and despite significant advances in therapeutic ma...

  • Review
  • Open Access
4 Citations
1 Views
6 Pages

The Novel Role of Epigenetics in Primary Prevention of Cardiovascular Diseases

  • Claudio Napoli,
  • Amelia Casamassimi,
  • Vincenzo Grimaldi,
  • Concetta Schiano,
  • Teresa Infante,
  • Alberto Zullo,
  • Maria Lourdes Montesano,
  • Laura Auriemma,
  • Francesco Paolo De Luca and
  • Francesco Paolo Mancini
  • + 2 authors

A great deal of evidences indicate that impaired fetal growth and in utero exposure to risk factors, especially maternal hypercholesterolemia, may be relevant for human pathophysiological signs of atherosclerosis and subsequent development of cardiov...

  • Review
  • Open Access
1 Citations
10,988 Views
17 Pages

10 February 2025

Cardiovascular diseases (CVDs) are a group of disorders of the heart and blood vessels and include coronary heart disease, cerebrovascular disease, rheumatic heart disease, and other conditions, which are leading causes of global morbidity and mortal...

  • Review
  • Open Access
1 Citations
2,082 Views
20 Pages

Biomarkers for Personalised Primary or Secondary Prevention in Cardiovascular Diseases: A Rapid Scoping Review

  • Chantal Babb de Villiers,
  • Elena Plans-Beriso,
  • Chaitanya Erady,
  • Laura Blackburn,
  • Hayley Wilson,
  • Heather Turner,
  • Isla Kuhn,
  • Cristina Barahona-López,
  • Paul Diez-Echave and
  • Mark Kroese
  • + 11 authors

24 September 2025

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality globally. Early detection and personalised prevention strategies are crucial for reducing the burden of CVD. The use of biomarkers plays a pivotal role in identifying ind...

  • Review
  • Open Access
102 Citations
9,882 Views
21 Pages

Phenolic Compounds Isolated from Olive Oil as Nutraceutical Tools for the Prevention and Management of Cancer and Cardiovascular Diseases

  • Patricia Reboredo-Rodríguez,
  • Alfonso Varela-López,
  • Tamara Y. Forbes-Hernández,
  • Massimiliano Gasparrini,
  • Sadia Afrin,
  • Danila Cianciosi,
  • Jiaojiao Zhang,
  • Piera Pia Manna,
  • Stefano Bompadre and
  • Francesca Giampieri
  • + 2 authors

Non-communicable diseases (NCDs) have become the largest contributor to worldwide morbidity and mortality. Among them, cancer and cardiovascular diseases (CVDs) are responsible for a 47% of worldwide mortality. In general, preventive approaches modif...

  • Review
  • Open Access
19 Citations
15,034 Views
8 Pages

Nutrition advice is devolved within each of the four UK countries, but share a common evidence base provided through the Scientific Advisory Committee on Nutrition (SACN). Current UK dietary recommendations to prevent cardiovascular disease (CVD) is...

  • Article
  • Open Access
34 Citations
8,437 Views
15 Pages

Modifying Health Behavior to Prevent Cardiovascular Diseases: A Nationwide Survey among German Primary Care Physicians

  • Sven Schneider,
  • Katharina Diehl,
  • Christina Bock,
  • Raphael M. Herr,
  • Manfred Mayer and
  • Tatiana Görig

Cardiovascular diseases (CVD) are a major public health concern as they are the leading cause of death in developed countries. Primary care is considered to be the ideal setting for CVD prevention. Therefore, more than 4,000 German primary care physi...

  • Article
  • Open Access
1,183 Views
21 Pages

18 August 2025

Background: Cardiovascular diseases (CVD) remain the leading cause of death in both Poland and worldwide. Despite a decline in CVD-related mortality observed in Poland since 1991, national rates still exceed the European Union average. Methods: The a...

  • Review
  • Open Access
38 Citations
6,618 Views
16 Pages

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are believed to be important for cardiovascular health. Many investigations have been carried out in an attempt to examine the effect of n-3 PUFAs intake, in the form of supplementation or fortified foo...

  • Article
  • Open Access
5 Citations
2,598 Views
23 Pages

From Waste to Health: Olive Mill Wastewater for Cardiovascular Disease Prevention

  • Laura Beatrice Mattioli,
  • Ivan Corazza,
  • Roberta Budriesi,
  • Silvana Hrelia,
  • Marco Malaguti,
  • Cristiana Caliceti,
  • Rosa Amoroso,
  • Cristina Maccallini,
  • Pasquale Crupi and
  • Filomena Corbo
  • + 5 authors

4 September 2024

Waste from the agri-food chain represents a valuable reservoir of organic compounds with health-promoting properties. Momast Plus 30 Bio (MP30B) is a derivative obtained from olive-oil wastewater. Its enrichment in hydroxytyrosol (HT) via a patented...

  • Review
  • Open Access
13 Citations
4,913 Views
13 Pages

25 June 2015

Atherosclerosis is considered a generalized disease. Similar or identical etiopathogenetic mechanisms and risk factors are involved in various atherosclerotic diseases, and the positive effects of preventive measures on atherogenesis in different par...

  • Article
  • Open Access
17 Citations
5,998 Views
26 Pages

Cardiovascular diseases are the world’s leading cause of mortality, with a high burden especially among vulnerable populations. Interventions for primary prevention need to be further implemented in community and primary health care settings. C...

  • Review
  • Open Access
20 Citations
7,887 Views
17 Pages

Sedentary Behaviour—A Target for the Prevention and Management of Cardiovascular Disease

  • Abbie C. Bell,
  • Joanna Richards,
  • Julia K. Zakrzewski-Fruer,
  • Lindsey R. Smith and
  • Daniel P. Bailey

Cardiovascular disease (CVD) is highly prevalent and can lead to disability and premature mortality. Sedentary behaviour, defined as a low energy expenditure while sitting or lying down, has been identified as an independent risk factor for CVD. This...

  • Review
  • Open Access
11 Citations
5,081 Views
18 Pages

More than 10.74 million people are currently held in penal institutions worldwide. Moreover, there is also evidence that the percentage of elder and female prisoners has been consistently growing. Cardiovascular diseases are the leading cause of deat...

  • Review
  • Open Access
9 Citations
4,988 Views
12 Pages

22 November 2023

Although various guidelines for cardiovascular disease prevention have been established, the optimal drug therapy is often not implemented due to poor medication adherence and the clinical inertia of healthcare practitioners. Polypill strategies are...

  • Review
  • Open Access
33 Citations
7,571 Views
13 Pages

Cardiovascular Disease Prevention in Adolescents: eHealth, Co-Creation, and Advocacy

  • Rebecca Raeside,
  • Stephanie R. Partridge,
  • Anna Singleton and
  • Julie Redfern

24 February 2019

Cardiovascular disease (CVD) is the leading cause of death globally. Early atherosclerotic changes can begin to occur early in life and though adolescence. The prevalence of modifiable CVD risk factors, namely, smoking, poor diet quality, excessive a...

  • Abstract
  • Open Access
1,633 Views
2 Pages

Do Statin Users Adhere to Dietary Recommendations for Cardiovascular Disease Prevention?

  • Milica Zrnic Ciric,
  • Jelena Kotur-Stevuljevic,
  • Brizita Djordjevic,
  • Vanja Todorovic,
  • Ivana Baralic,
  • Miodrag Ostojic and
  • Ivan Stankovic

Emerging evidence suggests that there is an interplay between the effects of diet and lipid-lowering therapy in primary and secondary prevention of cardiovascular disease. All prevention strategies focus on modifiable risk factors, with special atten...

  • Review
  • Open Access
9 Citations
5,667 Views
33 Pages

The Polypill: A New Alternative in the Prevention and Treatment of Cardiovascular Disease

  • Enma V. Páez Espinosa,
  • Eugenia Mato Matute,
  • Delia M. Sosa Guzmán and
  • Fadi T. Khasawneh

29 May 2024

Cardiovascular disease (CVD) is the primary cause of death and disability worldwide. Although age-standardized CVD mortality rates decreased globally by 14.5% between 2006 and 2016, the burden of CVD remains disproportionately higher in low- and midd...

  • Review
  • Open Access
20 Citations
6,353 Views
32 Pages

Women have been reported to be more vulnerable to the development, prognosis and mortality of cardiovascular diseases, yet the understanding of the underlying mechanisms and strategies to overcome them are still relatively undeveloped. Studies show t...

  • Review
  • Open Access
163 Citations
49,894 Views
13 Pages

28 February 2017

Natto, a fermented soybean product, has been consumed as a traditional food in Japan for thousands of years. Nattokinase (NK), a potent blood-clot dissolving protein used for the treatment of cardiovascular diseases, is produced by the bacterium Baci...

  • Review
  • Open Access
7 Citations
4,687 Views
26 Pages

Can Bioactive Food Substances Contribute to Cystic Fibrosis-Related Cardiovascular Disease Prevention?

  • Laura Mihaela Trandafir,
  • Otilia Elena Frăsinariu,
  • Elena Țarcă,
  • Lăcrămioara Ionela Butnariu,
  • Maria Magdalena Leon Constantin,
  • Mihaela Moscalu,
  • Oana Raluca Temneanu,
  • Alina Sinziana Melinte Popescu,
  • Marian George Melinte Popescu and
  • Stefana Maria Moisa
  • + 2 authors

8 January 2023

Advances in cystic fibrosis (CF) care have significantly improved the quality of life and life expectancy of patients. Nutritional therapy based on a high-calorie, high-fat diet, antibiotics, as well as new therapies focused on CFTR modulators change...

  • Review
  • Open Access
2 Citations
2,361 Views
14 Pages

29 January 2025

Calcific aortic stenosis (CAS) is currently recognized as the third most frequent cardiovascular disorder in persons aged above 60 years, after atherosclerotic disease and hypertension, and together with its precursor aortic sclerosis it has been fou...

  • Review
  • Open Access
10 Citations
5,387 Views
17 Pages

COVID-19 Associated Cardiovascular Disease—Risks, Prevention and Management: Heart at Risk Due to COVID-19

  • Andrew Kemerley,
  • Abhishek Gupta,
  • Mahesh Thirunavukkarasu,
  • Monica Maloney,
  • Sean Burgwardt and
  • Nilanjana Maulik

29 February 2024

The SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) virus and the resulting COVID-19 pandemic have had devastating and lasting impact on the global population. Although the main target of the disease is the respiratory tract, clinical ou...

  • Article
  • Open Access
2,260 Views
13 Pages

15 July 2024

Background: The effectiveness of aspirin for the primary prevention of cerebro-cardiovascular diseases in Koreans remains unclear. Therefore, we evaluated the preventive effects of low-dose aspirin (equal or less than 100 mg) on cerebro-cardiovascula...

  • Review
  • Open Access
3,177 Views
25 Pages

15 July 2025

Background: Cardiovascular disease (CVD) is very widespread in countries with a Western-style diet, representing one of the major causes of morbidity. Genetic factors, obesity, diabetes, dyslipidemia, smoking, and ageing are risk factors for CVD outc...

  • Review
  • Open Access
19 Citations
5,630 Views
19 Pages

24 December 2019

Atherosclerosis is the underlying cause of major cardiovascular events. The development of atherosclerotic plaques begins early in life, indicating that dietary interventions in childhood might be more effective at preventing cardiovascular disease (...

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