The PDZ family has drawn attention as possible drug targets because of the domains’ wide ranges of function and highly conserved binding pockets. The PICK1 PDZ domain has been proposed as a possible drug target because the interactions between...
Scaffolding proteins serve to assemble protein complexes in dynamic processes by means of specific protein-protein and protein-lipid binding domains. Many of these domains bind either proteins or lipids exclusively; however, it has become increasingl...
Strokes remain one of the leading causes of disability within the United States. Despite an enormous amount of research effort within the scientific community, very few therapeutics are available for stroke patients. Cytotoxic accumulation of intrace...
A DNA fragment encoding C-terminal BARc region (amino acids 128-416) of rat PICK1 (NP_445912 ) was inserted into a modified vector pMAL-s involving human rhinovirus 3C protease cleavage site to produce a recombinant plasmid, pMAL-s-barc. The construc...
In order to meet the demand of the intelligent and efficient picking of fresh citrus fruit in a natural environment, a flexible and independent picking method of fresh citrus fruit based on picking pattern recognition was proposed. The convolutional...
In order to effectively solve the problems of the complex growth state of dragon fruit and how the picking process is mostly manual, this study designed a picking and selecting integrated remote-operation-type dragon-fruit-picking device. Based on SO...
This work presents an industrial bin-picking framework for robotics called PickingDK. The proposed framework employs a plugin based architecture, which allows it to integrate different types of sensors, robots, tools, and available open-source softwa...
(1) Background: This work focuses on improving the efficiency of warehouse operations with the goal of promoting efficiency in the logistics industry and mitigating logistics-related labor shortages. Many factors are involved in warehouse operations,...
Well-tolerated and effective drugs for treating chronic pain conditions are urgently needed. Most chronic pain patients are not effectively relieved from their pain and suffer from debilitating drug side effects. This has not only drastic negative co...
Online shopping is growing fast due to the increasingly widespread use of digital services. During the COVID-19 pandemic, the desire for contactless shopping has further changed consumer behavior and accelerated the acceptance of online grocery purch...
The human manual order-picking process in the warehouse is still the leading method despite increasing automation. This manual process is supported by indicating and receipt systems to reduce the order-picking time and the number of errors. Many stud...
7 December 2022
With the vigorous development of e-commerce, efficient order picking in e-commerce warehouses has attracted the attention of many scholars. To analyze the issues about order-picking efficiency currently being studied by relevant scholars in e-commerc...
In view of the problem that peanut harvesting in hilly areas mainly involves fresh food, and that the peanut-picking purity rate is low and there is high breakage in the peanut-harvesting process, key components such as the picking system of a fresh-...
Aiming at the current complex problem of the mechanized high-quality picking of tender tea buds, this paper designs a tender tea bud-picking manipulator. In the picking process, the quality of the petiole and leaf blade of the tender tea bud is cruci...
Based on the structural shortage of an agricultural labor force and the continuous increase in tomato planting scale in China, as well as the limitation of a greenhouse working environment on the development of tomato picking productivity, a motor-dr...
A new bending fracture principle is proposed for ear picking by simulating the process of manually breaking off corn cobs. Based on this, a new test device for corn ear picking was designed to obtain the relationship between the ear-picking rate and...
Pick’s disease (PiD) is a devastating neurodegenerative disease that is characterized by dementia, frontotemporal lobar degeneration, and the aggregation of 3R tau in pathognomonic inclusions known as Pick bodies. The term PiD has adopted many...
Background: Despite the general impression that digital order-picking supportive technologies can manage a series of emerging challenges, there is still a very limited amount of research concerning the implementation and evaluation of such technologi...
23 February 2022
The Skin Picking Scale-Revised (SPS-R) is an 8-item self-report measure of skin picking behaviors. It includes two subscales related to skin picking symptom severity and picking-related impairments. The study aimed to assess the psychometric properti...
In response to the issues of high honeysuckle-picking costs and low efficiency in honeysuckle picking, this study has devised a comb-brush-type picking device, considering the unique characteristics of honeysuckle plants. We elucidated the device&rsq...
Aiming at the problem of automatic path planning for the whole safflower bulbs during the operation of safflower picking robots, an improved ant colony algorithm (ACA) was proposed to plan the three-dimensional path of the safflower picking points. T...
To solve tomato planting problems, such as high labor intensity and low efficiency, we designed a stretchable style pick-up device, which met the requirements of whole-row picking and improved the efficiency and speed of seedling picking. We designed...
Robotic bin-picking performance has been gaining attention in recent years with the development of increasingly advanced camera and machine vision systems, collaborative and industrial robots, and sophisticated robotic grippers. In the random bin-pic...
Background: Order picking is a critical activity in end-product warehouses, particularly using the picker-to-part system, entail substantial manual labor, representing approximately 60% of warehouse work. Methods: This study develops a new linear mod...
A visual system is a key tool for automatic fruit harvesting. It faces the challenges of varied occlusion and illumination in the field, resulting in difficulties in fruit recognition and picking. At present, there are many studies that lack a compre...
Considering the problems of the low mechanical work rate and the high picking damage rate of baffle roller bionic picking devices in the harvesting process of fresh corn in China, a method of fresh corn harvesting based on dislocation baffle roller b...
In order to realize the automatic picking of shiitake mushrooms and reduce the risk of damage to shiitake mushrooms in the picking process, this paper designed a shiitake mushroom picking grasper. First, this paper carries out mechanical tests of com...
30 December 2022
Due to the intense seasonality, high labor intensity, and high cost, picking fruit and vegetables typically requires a significant amount of personnel, material resources, and time. The fruit and vegetable picking is a critical role in the agricultur...
Litchi is a highly favored fruit with high economic value. Mechanical automation of litchi picking is a key link for improving the quality and efficiency of litchi harvesting. Our research team has been conducting experiments to develop a visual-base...
In the context of increasingly competitive shipbuilding, the flexible multi-level picking system, composed of high-rise shelves, Automated Guided Vehicles (AGVs), and picking stations, has been of gradual interest because of its advantages in operati...
The citrus picking-point localization is critical for automatic citrus harvesting. Due to the complex citrus growing environment and the limitations of devices, the efficient citrus picking-point localization method becomes a hot research topic. This...
During the process of automated crop picking, the two hand–eye coordination operation systems, namely “eye to hand” and “eye in hand” have their respective advantages and disadvantages. It is challenging to simultaneousl...
Recent literature demonstrates that warehouse order picking performance is reflected in the logistics performance of downstream retailers. Warehouse solutions and policies significantly contribute to the improvement of distribution and delivery to re...
The land used for fruit cultivation now exceeds 120 million hectares globally, with an annual yield of nearly 940 million tons. Fruit picking, the most labor-intensive task in agricultural production, is gradually shifting toward automation using int...
In this study, a closed multi-channel air-blowing plug seedling pick-up device and a combined plug tray were designed to address the issues of complex structure, high seedling damage rates and low pick-up efficiency in fully automated vegetable trans...
Order picking is the part with the highest proportion of operation cost and time in the warehouse. The characteristics of small-batch and multi-frequency current orders reduce the applicability of the traditional layout in the warehouse. Besides this...
Picking clothing has always been a great challenge in laundry or textile industry automation, especially when some clothes are of the same colors, material and entangled with each other. In order to solve the problem, we present a grasp pose determin...
Path planning for picking safflowers is a key component in ensuring the efficient operation of robotic safflower-picking systems. However, existing single-arm picking devices have become a bottleneck due to their limited operating range, and a breakt...
The spindle is a key core component of a cotton picker, and its operating parameters directly affect the quality of cotton harvesting. In this study, the spindle was selected as the research object. The kinematics and mechanics analysis of the cotton...
This study tries to make some improvements in the order picking operations by offering a novel mathematical model and efficient solution algorithm. Accordingly, the order picking policies are examined to allow for picking more orders by reducing the...
As a core component of a fully automatic pepper transplanter, the performance of the seedling-picking mechanism is of particular significance. However, existing seedling-picking mechanisms have problems such as being prone to damaging the seedling ro...
The tea industry is one of China’s most important industries. The picking of famous tea still relies on manual methods, with low efficiency, labor shortages and high labor costs, which restrict the development of the tea industry. These labor-i...
The tomato picking lifting platform is the carrier for the installation of the picking manipulator, which directly affects the operating range, speed, and picking effect of the picking manipulator. Based on the six degree of freedom motion platform,...
In the ridesourcing industry, drivers are often unable to quickly and accurately locate the waiting position of riders, but patrol or wait on the road, which will seriously affect the management of the road traffic order. It may be a good idea to pro...
Currently, companies are called to meet variable market demand whilst having to comply with tighter delivery times, also due to the growing spread of e-commerce systems in the last decade. As never before, it is therefore mandatory to increase the ef...
Influenced by the maturity and material properties, fresh corn has problems, such as low picking rate, high energy consumption and high damage rate during mechanized harvesting. For the above problems, a bionic reverse picking header was designed usi...
Research into autonomous (robotic) apple picking has not yet resolved the problem of finding the optimal picking orientation. Robotic picking efficiency, in terms of picking all available apples without loss or damage, remains low. This paper propose...
In this paper, a greenhouse tomato picking robot chassis that meets the path cruising and setpoint positioning requirements of robots engaged in greenhouse tomato picking operations in China is designed. Based on the trellis-cultivation growing envir...
In order to increase the efficiency of the order-picking process, warehouses are forced to find ways to adopt to constantly intensifying changes in the assortment and quantities of stored products. Accordingly, we present a methodology that deals wit...
China has the largest output of litchi in the world. However, at present, litchi is mainly picked manually, fruit farmers have high labor intensity and low efficiency. This means the intelligent unmanned picking system has broad prospects. The precis...
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