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21 Results Found

  • Article
  • Open Access
1 Citations
923 Views
17 Pages

Reduced MdFLS Expression Decreases Flavonol Content in Apple Flesh

  • Yarong Wang,
  • Zhenli Yan,
  • Zhe Zhou,
  • Qiming Gao and ,
  • Zhenzhen Liu,
  • Xiangpeng Meng,
  • Yaru Zhang,
  • Chunyan Wang,
  • Pengmin Li and
  • Jia-Long Yao
  • + 12 authors+ 7 authors

28 February 2026

Flavonols contribute significantly to both plant defense and human health. In apple (Malus domestica), flavonols accumulate at high levels in leaves and fruit skin but are present at low levels in the fruit flesh, the primary tissue consumed by human...

(This article belongs to the Section Crop Physiology and Crop Production)
  • Article
  • Open Access
24 Citations
4,018 Views
16 Pages

MdSCL8 as a Negative Regulator Participates in ALA-Induced FLS1 to Promote Flavonol Accumulation in Apples

  • Haiwen Zhang,
  • Huihui Tao,
  • Hao Yang,
  • Liuzi Zhang and ,
  • Guizhi Feng,
  • Yuyan An and
  • Liangju Wang
  • + 2 authors+ 0 author

12 February 2022

Apples (Malus domestica) are rich in flavonols, and 5-aminolevulinic acid (ALA) plays an important role in the regulation of plant flavonoid metabolism. To date, the underlying mechanism of ALA promoting flavonol accumulation is unclear. Flavonol syn...

(This article belongs to the Special Issue Functions of Transcription Factors in Plant Growth, Performance and Responses to Environmental Stresses 2.0)
  • Article
  • Open Access
1,276 Views
18 Pages

FL-MD3QN-Based IoT Intelligent Access Algorithm for Smart Construction Sites

  • Qiangwen Zong,
  • Jiaxiang Xu,
  • Wenqiang Li,
  • Feng Pan and ,
  • Wenting Wang,
  • Yang Liao and
  • Yong Liao
  • + 2 authors+ 0 author

With the deployment of fifth-generation (5G) mobile communication technology and rapid advancements in artificial intelligence and edge computing, smart construction sites have emerged as a critical direction for the construction industry’s tra...

  • Article
  • Open Access
50 Citations
6,464 Views
18 Pages

Identification of Two Novel R2R3-MYB Transcription factors, PsMYB114L and PsMYB12L, Related to Anthocyanin Biosynthesis in Paeonia suffruticosa

  • Xinpeng Zhang,
  • Zongda Xu,
  • Xiaoyan Yu,
  • Lanyong Zhao and ,
  • Mingyuan Zhao,
  • Xu Han and
  • Shuai Qi
  • + 2 authors+ 0 author

28 February 2019

Flower color is a charming phenotype with very important ornamental and commercial values. Anthocyanins play a critical role in determining flower color pattern formation, and their biosynthesis is typically regulated by R2R3-MYB transcription factor...

(This article belongs to the Special Issue Plant Genetics and Molecular Breeding)
  • Article
  • Open Access
7 Citations
3,029 Views
8 Pages

Real-World Analysis of the Aging Effects on Visual Field Reliability Indices in Humans

  • Tomoki Shirakami,
  • Tetsuro Omura,
  • Hiroki Fukuda,
  • Ryo Asaoka and
  • Masaki Tanito

9 December 2021

Relationships between age and visual field (VF) reliability indices were investigated using a large real-world dataset (42,421 VF data points from 11,525 eyes of 5930 subjects). All VFs tested and stored at Shimane University Hospital between 1988 an...

(This article belongs to the Special Issue Big Data and Artificial Intelligence-Driven Research in Ophthalmology)
  • Article
  • Open Access
23 Citations
6,282 Views
14 Pages

Associations of Human Milk Oligosaccharides with Infant Brain Tissue Organization and Regional Blood Flow at 1 Month of Age

  • Paige K. Berger,
  • Ravi Bansal,
  • Siddhant Sawardekar,
  • Chloe Yonemitsu and ,
  • Annalee Furst,
  • Hailey E. Hampson,
  • Kelsey A. Schmidt,
  • Tanya L. Alderete,
  • Lars Bode and
  • Bradley S. Peterson
  • + 6 authors+ 1 author

16 September 2022

Animal studies have shown that human milk oligosaccharides (HMOs) are important in early brain development, yet their roles have not been assessed in humans. The purpose of this study was to determine the associations of HMOs with MRI indices of tiss...

(This article belongs to the Section Pediatric Nutrition)
  • Article
  • Open Access
9 Citations
3,253 Views
15 Pages

Human Milk Oligosaccharide 2′-Fucosyllactose Inhibits Ligand Binding to C-Type Lectin DC-SIGN but Not to Langerin

  • Reshmi Mukherjee,
  • Victor J. Somovilla,
  • Fabrizio Chiodo,
  • Sven Bruijns and ,
  • Roland J. Pieters,
  • Johan Garssen,
  • Yvette van Kooyk,
  • Aletta D. Kraneveld and
  • Jeroen van Bergenhenegouwen
  • + 4 authors+ 0 author

25 November 2022

Human milk oligosaccharides (HMOs) and their most abundant component, 2′-Fucosyllactose (2′-FL), are known to be immunomodulatory. Previously, it was shown that HMOs and 2′-FL bind to the C-type lectin receptor DC-SIGN. Here we show...

(This article belongs to the Special Issue Galectins: Structure, Function and Therapeutic Inhibitors)
  • Article
  • Open Access
3 Citations
2,020 Views
19 Pages

18 April 2024

Federated learning (FL) in mobile edge computing has emerged as a promising machine-learning paradigm in the Internet of Things, enabling distributed training without exposing private data. It allows multiple mobile devices (MDs) to collaboratively c...

(This article belongs to the Special Issue Sensing and Mobile Edge Computing)
  • Article
  • Open Access
6 Citations
1,367 Views
10 Pages

27 August 2024

(1) Background: Previous research has investigated the relationship between cognitive impairment, optical coherence tomography (OCT), visual fields (VF), and VF reliability in smaller patient samples using various cognitive assessment tools. This stu...

(This article belongs to the Section Ophthalmology)
  • Feature Paper
  • Article
  • Open Access
82 Citations
14,584 Views
16 Pages

Evaluation of Single Photon and Geiger Mode Lidar for the 3D Elevation Program

  • Jason M. Stoker,
  • Qassim A. Abdullah,
  • Amar Nayegandhi and
  • Jayna Winehouse

19 September 2016

Data acquired by Harris Corporation’s (Melbourne, FL, USA) Geiger-mode IntelliEarth™ sensor and Sigma Space Corporation’s (Lanham-Seabrook, MD, USA) Single Photon HRQLS sensor were evaluated and compared to accepted 3D Elevation Program (3DEP) data a...

(This article belongs to the Special Issue Airborne Laser Scanning)
  • Article
  • Open Access
1,090 Views
17 Pages

A comprehensive MD + QC methodology was developed and applied to evaluate various aspects of Arbidol interactions with functional amino acids of surface proteins of influenza virus and SARS-CoV-2. The spatial structure, solvation features, conformati...

(This article belongs to the Special Issue Computer-Aided Drug Design and Molecular Synthesis)
  • Article
  • Open Access
5 Citations
2,812 Views
17 Pages

Ligand modification by substituting chemical groups within the binding pocket is a popular strategy for kinase drug development. In this study, a series of pteridin-7(8H)-one derivatives targeting wild-type FMS-like tyrosine kinase-3 (FLT3) and its D...

(This article belongs to the Special Issue QSAR and Chemoinformatics in Molecular Modeling and Drug Design 4.0)
  • Article
  • Open Access
1 Citations
1,397 Views
21 Pages

10 August 2025

Federated Clustering (FL clustering) aims to discover latent knowledge in multi-source distributed data through clustering algorithms while preserving data privacy. Federated learning is categorized into horizontal and vertical federated learning bas...

  • Article
  • Open Access
604 Views
16 Pages

Differential Associations of Cognitive Function, Frailty, and Comorbidity Burden with Visual Field Sensitivity and Reliability in Glaucoma

  • Yuya Kato,
  • Mayumi Furue,
  • Chisako Ida,
  • Hinako Ohtani and ,
  • Kana Murakami,
  • Mizuki Koike,
  • Keigo Takagi,
  • Yuto Yoshida,
  • Kazunobu Sugihara and
  • Masaki Tanito
  • + 5 authors+ 0 author

Background/Objectives: Cognitive impairment, frailty, and systemic comorbidity burden are common in elderly patients with glaucoma and may influence both visual field (VF) performance and glaucoma severity. This study investigated the associations of...

(This article belongs to the Special Issue Glaucoma: New Diagnostic and Therapeutic Approaches, 3rd Edition)
  • Article
  • Open Access
6 Citations
2,118 Views
21 Pages

11 March 2025

This work analyzes high-power wind turbines (WTs) from the Oravita region, Romania. These WTs are based on slip ring induction generator with wound rotor and we propose a modified architecture with two power converters on both the stator and on the r...

(This article belongs to the Special Issue 2024 and 2025 Selected Papers from Algorithms Editorial Board Members)
  • Article
  • Open Access
3 Citations
3,351 Views
10 Pages

Dimensional Accuracy of Polyether Elastomeric Impression Materials After Using Chitosan as a Disinfectant: A Sustainable Approach to Dental Infection Control

  • Noha Taymour,
  • Dooa I. Alabdrubalameer,
  • Zahra H. Al Shooq,
  • Maram S. Al Yaseen and ,
  • Rabab H. Al Zaher,
  • Ashwin C. Shetty and
  • Shimaa Rifaat
  • + 2 authors+ 0 author

Background: With the growing demand for sustainable dental practices, chitosan has evolved as an eco-friendly disinfectant for polyether impressions. Objectives: The present study investigated the disinfectant efficacy of chitosan on the dimensional...

(This article belongs to the Section Prosthodontics)
  • Article
  • Open Access
39 Citations
8,183 Views
18 Pages

What Protective Health Measures Are Americans Taking in Response to COVID-19? Results from the COVID Impact Survey

  • Fares Qeadan,
  • Nana Akofua Mensah,
  • Benjamin Tingey,
  • Rona Bern and ,
  • Tracy Rees,
  • Sharon Talboys,
  • Tejinder Pal Singh,
  • Steven Lacey and
  • Kimberley Shoaf
  • + 4 authors+ 0 author

With the emergence of the novel SARS-CoV-2 and the disease it causes; COVID-19, compliance with/adherence to protective measures is needed. Information is needed on which measures are, or are not, being undertaken. Data collected from the COVID Impac...

(This article belongs to the Special Issue Disasters and Their Consequences for Public Health)
  • Article
  • Open Access
10 Citations
4,372 Views
16 Pages

Effects of Hippocampal Sparing Radiotherapy on Brain Microstructure—A Diffusion Tensor Imaging Analysis

  • Johannes G. Dinkel,
  • Godehard Lahmer,
  • Angelika Mennecke,
  • Stefan W. Hock and ,
  • Tanja Richter-Schmidinger,
  • Rainer Fietkau,
  • Luitpold Distel,
  • Florian Putz,
  • Arnd Dörfler and
  • Manuel A. Schmidt
  • + 5 authors+ 0 author

Hippocampal-sparing radiotherapy (HSR) is a promising approach to alleviate cognitive side effects following cranial radiotherapy. Microstructural brain changes after irradiation have been demonstrated using Diffusion Tensor Imaging (DTI). However, e...

(This article belongs to the Special Issue Human Brain Dynamics: Latest Advances and Prospects—2nd Edition)
  • Article
  • Open Access
1,245 Views
26 Pages

MetaGAN: Metamorphic GAN-Based Augmentation for Improving Deep Learning-Based Multiple-Fault Localization Without Test Oracles

  • Anlin Hu,
  • Wenjiang Feng,
  • Xudong Zhu,
  • Junjie Wang and ,
  • Yiping Ao and
  • Hao Feng
  • + 1 author+ 0 author

Modern electronic information system software is becoming increasingly complex, making manual debugging prohibitively expensive and necessitating automated fault localization (FL) methods to prioritize suspicious code segments. While Single-Fault Loc...

(This article belongs to the Special Issue Software Analysis, Quality, and Security)
  • Article
  • Open Access
10 Citations
3,038 Views
20 Pages

3D Autonomous Surgeon’s Hand Movement Assessment Using a Cascaded Fuzzy Supervisor in Multi-Thread Video Processing

  • Fatemeh Rashidi Fathabadi,
  • Janos L. Grantner,
  • Saad A. Shebrain and
  • Ikhlas Abdel-Qader

27 February 2023

The purpose of the Fundamentals of Laparoscopic Surgery (FLS) training is to develop laparoscopic surgery skills by using simulation experiences. Several advanced training methods based on simulation have been created to enable training in a non-pati...

(This article belongs to the Special Issue Sensor-Based Motion Analysis in Medicine, Rehabilitation and Sport)
  • Article
  • Open Access
25 Citations
2,826 Views
15 Pages

25 July 2022

Background: Our primary aim is to quantify test reliability and compliance of glaucoma patients to a weekly visual field telemedicine (VFTM) schedule. A secondary aim is to determine concordance of the VFTM results to in-clinic outcomes. Methods: Par...

(This article belongs to the Section Ophthalmology)