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23 Results Found

  • Article
  • Open Access
18 Citations
5,050 Views
19 Pages

Modulating p-AMPK/mTOR Pathway of Mitochondrial Dysfunction Caused by MTERF1 Abnormal Expression in Colorectal Cancer Cells

  • Qianqian Liu,
  • Longlong Zhang,
  • Yayan Zou,
  • Ying Tao and ,
  • Bing Wang,
  • Bin Li,
  • Ruai Liu,
  • Boyong Wang,
  • Lei Ding and
  • Min Yu
  • + 9 authors+ 4 authors

15 October 2022

Human mitochondrial transcription termination factor 1 (MTERF1) has been demonstrated to play an important role in mitochondrial gene expression regulation. However, the molecular mechanism of MTERF1 in colorectal cancer (CRC) remains largely unknown...

(This article belongs to the Special Issue Targeting PI3K/AKT/mTOR Signaling Pathway in Cancer)
  • Communication
  • Open Access
32 Citations
4,985 Views
11 Pages

The Characterization of Arabidopsis mterf6 Mutants Reveals a New Role for mTERF6 in Tolerance to Abiotic Stress

  • Pedro Robles,
  • Sergio Navarro-Cartagena,
  • Almudena Ferrández-Ayela,
  • Eva Núñez-Delegido and
  • Víctor Quesada

Exposure of plants to abiotic stresses, such as salinity, cold, heat, or drought, affects their growth and development, and can significantly reduce their productivity. Plants have developed adaptive strategies to deal with situations of abiotic stre...

(This article belongs to the Special Issue Plant Mitochondria)
  • Article
  • Open Access
23 Citations
4,894 Views
25 Pages

3 February 2021

Plastid gene expression (PGE) is essential for chloroplast biogenesis and function and, hence, for plant development. However, many aspects of PGE remain obscure due to the complexity of the process. A hallmark of nuclear-organellar coordination of g...

(This article belongs to the Special Issue RNA Biology in Plant Organelles)
  • Article
  • Open Access
21 Citations
4,435 Views
19 Pages

Genome-Wide Identification and Characterization of the Mitochondrial Transcription Termination Factors (mTERFs) in Capsicum annuum L.

  • Bingqian Tang,
  • Lingling Xie,
  • Ting Yi,
  • Junheng Lv and ,
  • Huiping Yang,
  • Xiang Cheng,
  • Feng Liu and
  • Xuexiao Zou
  • + 3 authors+ 0 author

31 December 2019

Mitochondrial transcription termination factors (mTERFs) regulate the expression of mitochondrial genes and are closely related to the function of the mitochondrion and chloroplast. In this study, the mTERF gene family in capsicum (Capsicum annuum L....

(This article belongs to the Section Molecular Plant Sciences)
  • Article
  • Open Access
9 Citations
4,599 Views
12 Pages

2 February 2021

In plants, mTERF proteins are primarily found in mitochondria and chloroplasts. Studies have identified several mTERF proteins that affect plant development, respond to abiotic stresses, and regulate organellar gene expression, but the functions and...

(This article belongs to the Special Issue Cell Signaling in Model Plants 2.0)
  • Review
  • Open Access
33 Citations
5,540 Views
16 Pages

21 January 2021

Present-day chloroplast and mitochondrial genomes contain only a few dozen genes involved in ATP synthesis, photosynthesis, and gene expression. The proteins encoded by these genes are only a small fraction of the many hundreds of proteins that act i...

(This article belongs to the Special Issue RNA Biology in Plant Organelles)
  • Article
  • Open Access
11 Citations
2,904 Views
18 Pages

Analysis of the Tomato mTERF Gene Family and Study of the Stress Resistance Function of SLmTERF-13

  • Ao Su,
  • Siyu Ge,
  • Boyan Zhou,
  • Ziyu Wang and ,
  • Liping Zhou,
  • Ziwei Zhang,
  • Xiaoyu Yan,
  • Yu Wang,
  • Dalong Li and
  • Tingting Zhao
  • + 7 authors+ 2 authors

3 August 2023

Mitochondrial transcription termination factor (mTERF) is a DNA-binding protein that is encoded by nuclear genes, ultimately functions in mitochondria and can affect gene expression. By combining with mitochondrial nucleic acids, mTERF regulates the...

(This article belongs to the Special Issue Molecular Basis of Crops and Fruit Plants in Response to Stress)
  • Article
  • Open Access
1,032 Views
20 Pages

21 February 2026

Mitochondrial biogenesis requires coordinated expression from both nuclear and mitochondrial genomes. To understand the consequences of mitochondrial genome loss, we generated a mitochondrial DNA-depleted line (crm−) in Chlamydomonas reinhardti...

(This article belongs to the Special Issue Evolutionary Drivers and Adaptive Mechanisms in Algal Organellar Genomes)
  • Article
  • Open Access
3 Citations
1,588 Views
17 Pages

Genome-Wide Identification and Characterization of the mTERF Gene Family in Spinach and the Role of SomTERF5 in Response to Heat Stress

  • Ziyue Sun,
  • Li Li,
  • Yaqi Liu,
  • Yanshuang Liu and ,
  • Gaojian Li,
  • Yueyue Li,
  • Qingbo Yu,
  • Meihong Sun and
  • Xiaofeng Xu
  • + 4 authors+ 0 author

22 May 2025

Spinach (Spinacia oleracea L.), a globally consumed, nutrient-dense vegetable, contains diverse vitamins and minerals. However, elevated temperatures can constrain yield by interrupting leaf development and photosynthetic efficiency. The mitochondria...

(This article belongs to the Special Issue Growth, Development, and Stress Response of Horticulture Plants)
  • Review
  • Open Access
39 Citations
8,002 Views
16 Pages

28 February 2019

Given their endosymbiotic origin, chloroplasts and mitochondria genomes harbor only between 100 and 200 genes that encode the proteins involved in organellar gene expression (OGE), photosynthesis, and the electron transport chain. However, as the act...

(This article belongs to the Special Issue Organelle Genetics in Plants)
  • Article
  • Open Access
12 Citations
3,840 Views
16 Pages

Genomic Scan of Male Fertility Restoration Genes in a ‘Gülzow’ Type Hybrid Breeding System of Rye (Secale cereale L.)

  • Nikolaj Meisner Vendelbo,
  • Khalid Mahmood,
  • Pernille Sarup,
  • Peter Skov Kristensen and ,
  • Jihad Orabi and
  • Ahmed Jahoor
  • + 1 author+ 0 author

27 August 2021

Efficient and stable restoration of male fertility (Rf) is a prerequisite for large-scale hybrid seed production but remains an inherent issue in the predominant fertility control system of rye (Secale cereale L.). The ‘Gülzow’ (G)-type cytoplasmic m...

(This article belongs to the Collection Genetics and Molecular Breeding in Plants)
  • Article
  • Open Access
11 Citations
4,634 Views
19 Pages

Morpho-Physiological, Biochemical, and Genetic Responses to Salinity in Medicago truncatula

  • Sabrine Hdira,
  • Loua Haddoudi,
  • Mohsen Hanana,
  • Irene Romero and ,
  • Asma Mahjoub,
  • Hatem Ben Jouira,
  • Ndiko Ludidi,
  • Maria Teresa Sanchez-Ballesta,
  • Chedly Abdelly and
  • Mounawer Badri
  • + 5 authors+ 0 author

20 April 2021

We used an integrated morpho-physiological, biochemical, and genetic approach to investigate the salt responses of four lines (TN1.11, TN6.18, JA17, and A10) of Medicago truncatula. Results showed that TN1.11 exhibited a high tolerance to salinity, c...

(This article belongs to the Special Issue Molecular Analysis of Medicago Spp.)
  • Article
  • Open Access
2,206 Views
9 Pages

Larches of Kuzhanovo Have a Unique Mutation in the atpF–atpH Intergenic Spacer

  • Alexander Artyukhin,
  • Yuliya Sharifyanova,
  • Mikhail M. Krivosheev and
  • Elena V. Mikhaylova

15 February 2023

The larches of Kuzhanovo (Larix sibirica Ledeb.) are protected trees with a round crown growing in the Southern Urals. In 2020 vandals sawed the sapwood of these trees, which exposed the problem of insufficient conservation measures. Their origin and...

(This article belongs to the Collection Feature Papers in Molecular Genetics and Genomics)
  • Article
  • Open Access
6 Citations
2,859 Views
13 Pages

13 January 2023

Mitochondria are responsible for energy generation, as well as key metabolic and signaling pathways, and thus affect the entire developmental process of plants as well as their responses to stress. In metazoans, mitochondrial transcription terminatio...

(This article belongs to the Section Plant Genetics and Genomics)
  • Article
  • Open Access
6 Citations
3,169 Views
23 Pages

Constructing and Evaluating a Mitophagy-Related Gene Prognostic Model: Implications for Immune Landscape and Tumor Biology in Lung Adenocarcinoma

  • Jin Wang,
  • Kaifan Liu,
  • Jiawen Li,
  • Hailong Zhang and ,
  • Xian Gong,
  • Xiangrong Song,
  • Meidan Wei,
  • Yaoyu Hu and
  • Jianxiang Li
  • + 4 authors+ 0 author

16 February 2024

Mitophagy, a conserved cellular mechanism, is crucial for cellular homeostasis through the selective clearance of impaired mitochondria. Its emerging role in cancer development has sparked interest, particularly in lung adenocarcinoma (LUAD). Our stu...

(This article belongs to the Section Bioinformatics and Systems Biology)
  • Article
  • Open Access
7 Citations
2,955 Views
18 Pages

Phytohormones as Regulators of Mitochondrial Gene Expression in Arabidopsis thaliana

  • Ivan A. Bychkov,
  • Elena S. Pojidaeva,
  • Anastasia S. Doroshenko,
  • Vladimir A. Khripach and ,
  • Natalia V. Kudryakova and
  • Victor V. Kusnetsov
  • + 1 author+ 0 author

29 November 2023

The coordination of activities between nuclei and organelles in plant cells involves information exchange, in which phytohormones may play essential roles. Therefore, the dissection of the mechanisms of hormone-related integration between phytohormon...

(This article belongs to the Special Issue The Role of Cytokinins and Other Phytohormones in Plant Life)
  • Article
  • Open Access
22 Citations
8,985 Views
14 Pages

Transcriptome Profile of the Variegated Ficus microcarpa c.v. Milky Stripe Fig Leaf

  • Tin-Han Shih,
  • Szu-Hsien Lin,
  • Meng-Yuan Huang,
  • Wen-Dar Huang and
  • Chi-Ming Yang

Photosynthetic properties and transcriptomic profiles of green and white sectors of Ficus microcarpa (c.v. milky stripe fig) leaves were examined in naturally variegated plants. An anatomic analysis indicated that chloroplasts of the white sectors co...

(This article belongs to the Special Issue Photosynthesis)
  • Article
  • Open Access
4 Citations
2,913 Views
17 Pages

3 September 2020

Polyploidization is a universal phenomenon in plants and plays a crucial role in evolution. In this study, the transcriptomes of developing seeds of a synthetic Brassica hexaploid and its parents (B. rapa and B. carinata) were analyzed to find the ge...

(This article belongs to the Section Plant Genetics, Genomics and Biotechnology)
  • Feature Paper
  • Article
  • Open Access
2 Citations
1,161 Views
16 Pages

Knockout of MDHAR Paralogs Suggests Broader Regulatory Roles Beyond Ascorbic Acid Recycling in Lettuce

  • Ugo Rogo,
  • Samuel Simoni,
  • Ambra Viviani,
  • Claudio Pugliesi and ,
  • Marco Fambrini,
  • Alberto Vangelisti,
  • Lucia Natali,
  • Andrea Cavallini,
  • Richard Michelmore and
  • Tommaso Giordani
  • + 5 authors+ 0 author

Ascorbic acid (AsA) is a key antioxidant and nutrient in plants, regulating reactive oxygen species (ROS) levels and maintaining cellular redox homeostasis. The AsA recycling pathway sustains AsA pools by restoring its oxidized forms, ensuring intrac...

(This article belongs to the Section Genetics, Genomics, Breeding, and Biotechnology (G2B2))
  • Article
  • Open Access
31 Citations
5,482 Views
17 Pages

Genome-Wide Association Study Reveals Marker–Trait Associations for Early Vegetative Stage Salinity Tolerance in Rice

  • Ashutosh Kumar Yadav,
  • Aruna Kumar,
  • Nitasha Grover,
  • Ranjith Kumar Ellur and ,
  • Haritha Bollinedi,
  • Subbaiyan Gopala Krishnan,
  • Prolay Kumar Bhowmick,
  • Kunnummal Kurungara Vinod,
  • Mariappan Nagarajan and
  • Ashok Kumar Singh
  • + 5 authors+ 0 author

16 March 2021

Rice germplasm is a rich resource for discovering genes associated with salt tolerance. In the current study, a set of 96 accessions were evaluated for seedling stage salinity tolerance and its component traits. Significant phenotypic variation was o...

(This article belongs to the Special Issue Plants Subjected to Salinity Stress)
  • Article
  • Open Access
17 Citations
4,312 Views
15 Pages

Impact of Maternal Mediterranean-Type Diet Adherence on Microbiota Composition and Epigenetic Programming of Offspring

  • Tamlyn Sasaki,
  • Megan Kawamura,
  • Chirstyn Okuno,
  • Kayleen Lau and ,
  • Jonathan Riel,
  • Men-Jean Lee and
  • Corrie Miller
  • + 2 authors+ 0 author

22 December 2023

Understanding how maternal diet affects in utero neonatal gut microbiota and epigenetic regulation may provide insight into disease origins and long-term health. The impact of Mediterranean diet pattern adherence (MDA) on fetal gut microbiome and epi...

(This article belongs to the Special Issue The Role of Mediterranean Diet During Pregnancy on Maternal and Offspring Health)
  • Article
  • Open Access
3 Citations
1,900 Views
18 Pages

Light plays a crucial role in anthocyanin biosynthesis and color development in plants. Anthocyanins found in Lycium ruthenicum Murray are crucial for the plant’s defense against UV light and environmental stress, as well as for their economic...

(This article belongs to the Section Genetics, Genomics, Breeding, and Biotechnology (G2B2))
  • Article
  • Open Access
63 Citations
7,268 Views
26 Pages

7 April 2021

Rice is an important grain that is the staple food for most of the world’s population. Drought is one of the major stresses that negatively affects rice yield. The nature of drought tolerance in rice is complex as it is determined by various componen...

(This article belongs to the Special Issue Genetic Improvement of Cereal Crops for Resistance to Biotic and Abiotic Stresses)