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44 Results Found

  • Article
  • Open Access
5 Citations
5,617 Views
20 Pages

20 November 2024

The Fitzpatrick Skin Phototype Classification (FSPC) scale is widely used to categorize skin types but has limitations such as the underrepresentation of darker skin phototypes, low classification resolution, and subjectivity. These limitations may c...

  • Review
  • Open Access
9,320 Views
19 Pages

Laser Resurfacing Versus Chemical Peels: A Review of Current Trends and Technological Advances in Nonsurgical Facial Rejuvenation

  • Miranda X. Morris,
  • Susanna Gebhardt,
  • Joseph N. Tingen,
  • Miguel I. Dorante and
  • Sonal Pandya

Recent decades have seen a rapid advancement in nonsurgical facial rejuvenation techniques due to technological advances and growing patient preference for minimally invasive aesthetic procedures. Laser resurfacing and chemical peels are two popular...

  • Review
  • Open Access
11 Citations
23,899 Views
21 Pages

Treatment of Melasma on Darker Skin Types: A Scoping Review

  • Nomakhosi Mpofana,
  • Buyisile Chibi,
  • Tronel Visser,
  • Michael Paulse,
  • Avenal Jane Finlayson,
  • Shanaz Ghuman,
  • Nceba Gqaleni,
  • Ahmed A. Hussein and
  • Ncoza Cordelia Dlova

27 January 2023

Melasma is a challenging chronic skin condition associated with hyperpigmentation and unknown aetiology. This scoping review maps evidence of available treatments and their effectiveness in darker skin types. A comprehensive, systematic online search...

  • Article
  • Open Access
15 Citations
6,125 Views
22 Pages

The Effect of Melasma on the Quality of Life in People with Darker Skin Types Living in Durban, South Africa

  • Nomakhosi Mpofana,
  • Michael Paulse,
  • Nceba Gqaleni,
  • Mokgadi Ursula Makgobole,
  • Pavitra Pillay,
  • Ahmed Hussein and
  • Ncoza Cordelia Dlova

Melasma is a common skin disorder of acquired hyperpigmentation that appears commonly on the face. Although asymptomatic, melasma causes psychosocial and emotional distress. This study aimed to assess melasma’s severity on people with darker sk...

  • Article
  • Open Access
20 Citations
31,794 Views
12 Pages

Prospective Randomized Controlled Trial on the Effects of Almonds on Facial Wrinkles and Pigmentation

  • Iryna Rybak,
  • Alexis E. Carrington,
  • Simran Dhaliwal,
  • Aliza Hasan,
  • Hera Wu,
  • Waqas Burney,
  • Jessica Maloh and
  • Raja K. Sivamani

27 February 2021

Background: Almonds have long been studied as a rich source of fatty acids, phytochemical polyphenols and antioxidants such as vitamin E. A recent study compared almond supplementations to a calorie-matched intervention for 16 weeks, yielding statist...

  • Communication
  • Open Access
1 Citations
6,667 Views
11 Pages

Hyper- and Hypopigmentation in a Subject with Fitzpatrick Skin Phototype VI: A New Treatment Option

  • Sheila Veronese,
  • Rajeev Aggarwal,
  • Tiziana Giovanelli and
  • Andrea Sbarbati

11 February 2024

Background: Laser therapies can cause hyper- and hypopigmentation of the skin. There is little evidence in the literature of effective treatments for these types of problems in Fitzpatrick skin phototypes IV–VI. The main aim of this retrospecti...

  • Communication
  • Open Access
6 Citations
2,948 Views
13 Pages

15 November 2022

In recent years, skin spectral information has been gradually applied in various fields, such as the cosmetics industry and clinical medicine. However, the high price and the huge size of the skin spectrum measurement device make the related applicat...

  • Article
  • Open Access
26 Citations
18,958 Views
15 Pages

Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial

  • Julianne Rizzo,
  • Mildred Min,
  • Sarah Adnan,
  • Nasima Afzal,
  • Jessica Maloh,
  • Cindy J. Chambers,
  • Vivien Fam and
  • Raja K. Sivamani

23 September 2023

Preliminary findings from multiple studies indicate that dietary intake of soy-derived isoflavones exert beneficial effects on the skin including defense against oxidant damage, stimulation of collagen synthesis, and increased hydration. This study a...

  • Proceeding Paper
  • Open Access
2 Citations
1,854 Views
7 Pages

Public Health Messages Associated with the Low Exposure Category of the UV Index Need Reconsideration

  • Maria Lehmann,
  • Annette B. Pfahlberg,
  • Henner Sandmann,
  • Wolfgang Uter and
  • Olaf Gefeller

14 November 2018

Overexposure to ultraviolet (UV) radiation is the main modifiable risk factor for skin cancer. The Global Solar Ultraviolet Index (UVI) was introduced as a tool to visualize the intensity of UV radiation on a certain day which should enable and encou...

  • Review
  • Open Access
36 Citations
40,021 Views
15 Pages

An Overview of Methods to Characterize Skin Type: Focus on Visual Rating Scales and Self-Report Instruments

  • Rita Oliveira,
  • Joana Ferreira,
  • Luís Filipe Azevedo and
  • Isabel F. Almeida

11 January 2023

Skin type classification is important because it provides guidance for professionals and consumers to recommend and select the most appropriate cosmetic products and skin care protocols and it is also important in clinical research. Several methods h...

  • Review
  • Open Access
1 Citations
7,105 Views
14 Pages

Treatment of Benign Pigmented Lesions Using Lasers: A Scoping Review

  • Aurore D. Zhang,
  • Janelle Clovie,
  • Michelle Lazar and
  • Neelam A. Vashi

5 June 2025

Lasers are widely employed in the treatment of melanocytic lesions. This scoping review evaluates 77 studies on the efficacy and safety of laser treatments for café-au-lait macules (CALMs), nevus of Ota (NOA), Becker’s nevus (BN), lichen...

  • Review
  • Open Access
2 Citations
10,233 Views
15 Pages

A Scoping Review on Melasma Treatments and Their Histopathologic Correlates

  • Aurore D. Zhang,
  • Michelle Lazar,
  • Emiliya Akhundova,
  • Candice E. Brem,
  • Eric J. Beltrami and
  • Neelam A. Vashi

Melasma is an incredibly common dyschromic disorder, mostly impacting women with skin of color. There are three variants of melasma based on the depth of pathologic involvement: epidermal, mixed, and dermal. While there are many treatments for melasm...

  • Feature Paper
  • Article
  • Open Access
111 Citations
14,447 Views
7 Pages

Colour Counts: Sunlight and Skin Type as Drivers of Vitamin D Deficiency at UK Latitudes

  • Ann R. Webb,
  • Andreas Kazantzidis,
  • Richard C. Kift,
  • Mark D. Farrar,
  • Jack Wilkinson and
  • Lesley E. Rhodes

7 April 2018

Sunlight exposure, with resulting cutaneous synthesis, is a major source of vitamin D for many, while dietary intake is low in modern diets. The constitutive pigment in skin determines skin type, observed as white, brown, or black skin. The melanin p...

  • Communication
  • Open Access
9 Citations
6,519 Views
11 Pages

New 675 nm Laser Device: The Innovative and Effective Non-Ablative Resurfacing Technique

  • Domenico Piccolo,
  • Giuliana Crisman,
  • Caterina Dianzani,
  • Iris Zalaudek,
  • Irene Fusco and
  • Claudio Conforti

4 July 2023

Background and Objectives: Photo/chrono-aging is usually expressed as facial discolouration, wrinkles, redness, elastosis, laxity, and dehydration, thus representing major signs of ageing that often lead to a negative phycological impact on a patient...

  • Article
  • Open Access
6 Citations
15,173 Views
8 Pages

Picosecond Q-Switched 1064/532 nm Laser in Tattoo Removal: Our Single Center Experience

  • Luigi Bennardo,
  • Giovanni Cannarozzo,
  • Federica Tamburi,
  • Cataldo Patruno,
  • Eugenio Provenzano and
  • Steven Paul Nisticò

18 October 2021

Background: Tattoo removal is becoming increasingly popular, and Q-switched lasers represent the gold standard in the treatment of this condition. In this study, we report our experience with a new Q-switched picosecond laser device, evaluating its e...

  • Systematic Review
  • Open Access
1 Citations
2,568 Views
21 Pages

Background: Artificial intelligence (AI) developed for skin cancer recognition has been shown to have comparable or superior performance to dermatologists. However, it is uncertain if current AI models trained predominantly with lighter Fitzpatrick s...

  • Article
  • Open Access
2,995 Views
13 Pages

A Chronocosmetic Approach to Treating Signs of Aging with Glutathione

  • Candelaria Contreras-Agudelo,
  • Amin Ariza-Donado,
  • Mariana Villegas-Gallego,
  • Aura Villa-Sierra,
  • Jennifer Naranjo-Narvaez and
  • Isabella Martinez-Meza

17 October 2025

Cutaneous aging is associated with oxidative stress and visible changes on the skin, such as uneven pigmentation, wrinkles, and loss of radiance. Glutathione (GSH), an endogenous antioxidant with anti-melanogenic properties, is considered a promising...

  • Article
  • Open Access
11 Citations
7,437 Views
8 Pages

Q-Switched 1064/532 nm Laser with Nanosecond Pulse in Tattoo Treatment: A Double-Center Retrospective Study

  • Giovanni Cannarozzo,
  • Steven Paul Nisticò,
  • Elena Zappia,
  • Ester Del Duca,
  • Eugenio Provenzano,
  • Cataldo Patruno,
  • Francesca Negosanti,
  • Mario Sannino and
  • Luigi Bennardo

16 July 2021

Tattoo removal is a well-established procedure in dermatology. Lasers represent the gold standard in the management of this condition nowadays. In this study, we report our experience on the use of a Q-switched nanosecond source. A total of 52 patien...

  • Article
  • Open Access
11,614 Views
16 Pages

20 February 2025

Background: The US Food and Drug Administration (FDA) and International Organization for Standardization (ISO) clearance standards for the clinical use of smart device pulse oximetry require in-laboratory human hypoxemia testing in healthy human indi...

  • Article
  • Open Access
4 Citations
7,699 Views
20 Pages

16 September 2024

This study aimed to determine whether a polyphenol-rich cranberry beverage affects skin properties, lipids, and the microbiome in women using a randomized, double-blinded, placebo-controlled, cross-over design. Twenty-two women with Fitzpatrick skin...

  • Article
  • Open Access
10 Citations
21,110 Views
13 Pages

12 March 2024

Background: Facial hypermelanosis is a major cosmetic issue that causes severe social embarrassment and psychological pain, particularly among Asians and dark-skinned individuals. Aim: This study assesses the safety and effectiveness of Q-switched 10...

  • Article
  • Open Access
2 Citations
5,522 Views
21 Pages

AI Dermatochroma Analytica (AIDA): Smart Technology for Robust Skin Color Classification and Segmentation

  • Abderrachid Hamrani,
  • Daniela Leizaola,
  • Nikhil Kumar Reddy Vedere,
  • Robert S. Kirsner,
  • Kacie Kaile,
  • Alexander Lee Trinidad and
  • Anuradha Godavarty

10 December 2024

Traditional methods for skin color classification, such as visual assessments and conventional image classification, face limitations in accuracy and consistency under varying conditions. To address this, we developed AI Dermatochroma Analytica (AIDA...

  • Case Report
  • Open Access
520 Views
7 Pages

Reticulated acanthoma with sebaceous differentiation (RASD) is a rare, benign cutaneous neoplasm. Its variable clinical presentation frequently mimics both benign and malignant entities, posing a significant diagnostic challenge. We report a case of...

  • Article
  • Open Access
3 Citations
5,767 Views
11 Pages

Fluorescent Light Energy (FLE) Generated through Red LED Light and a Natural Photoconverter Gel as a New, Non-Invasive Approach for Facial Age Control: A Pilot Study

  • Giuseppe Scarcella,
  • Roberta Tardugno,
  • Pasquale Crupi,
  • Marilena Muraglia,
  • Maria Lisa Clodoveo and
  • Filomena Corbo

This study, for the first time, evaluated the safety and efficacy of a new natural-based topical gel containing a spirulina extract. This photoconverter gel generates fluorescent light energy (FLE) via a red LED light device, which is proven to be ef...

  • Review
  • Open Access
8 Citations
24,095 Views
27 Pages

20 August 2024

Melasma, also known as chloasma and the “mask of pregnancy”, is a common acquired pigmentary disorder characterized by irregular, hyperpigmented brown-to-grey patches primarily situated on the face. It typically affects women of reproduct...

  • Article
  • Open Access
527 Views
16 Pages

Point-of-Care Bilirubin Testing in Neonates: Comparative Performance of Blood Gas Analysis and Transcutaneous Bilirubinometry

  • Andrew Xu,
  • Bincy Francis,
  • Kay Weng Choy,
  • George Francis Dargaville,
  • Amy Surkitt,
  • David Tran,
  • Rami Subhi and
  • Wei Qi Fan

1 February 2026

Background: Neonatal jaundice is a common condition with potentially severe complications such as bilirubin-induced neurological dysfunction and kernicterus. While serum bilirubin (SBR) remains the standard laboratory measurement, point-of-care metho...

  • Article
  • Open Access
30 Citations
25,389 Views
11 Pages

4 November 2020

Mangos are rich in β-carotene and other carotenoids, along with several phenolic acids that may provide oxidant defense and photoprotection to the skin. The objectives of this study are to investigate the effects of Ataulfo mango intake on the d...

  • Article
  • Open Access
2 Citations
4,531 Views
24 Pages

Multi-Active Cosmeceutical Formulations: Stability, Sensory Performance, and Skin Tolerability

  • Magdalena Bîrsan,
  • Ecaterina Gore,
  • Șadiye-Ioana Scripcariu,
  • Robert-Alexandru Vlad,
  • Paula Antonoaea,
  • Cezara Pintea,
  • Andrada Pintea,
  • Cornelia-Titiana Cotoi,
  • Alin-Viorel Focșa and
  • Adriana Ciurba

8 September 2025

Cosmeceutical systems represent next-generation topical platforms designed to deliver bioactive molecules with therapeutic potential directly to the skin. This study evaluated four anti-wrinkle formulations (three creams and one emulgel) in terms of...

  • Article
  • Open Access
13 Citations
19,901 Views
12 Pages

Efficacy and Tolerability of a Microneedling Device Plus Exosomes for Treating Melasma

  • Ilaria Proietti,
  • Chiara Battilotti,
  • Francesca Svara,
  • Carlotta Innocenzi,
  • Alessandra Spagnoli and
  • Concetta Potenza

17 August 2024

Melasma is a challenging skin condition which involves both structural and functional skin alterations. Despite the availability of various treatment options, the management remains complex. This is the first study to investigate topical application...

  • Article
  • Open Access
26 Citations
65,653 Views
14 Pages

Public Health Messages Associated with Low UV Index Values Need Reconsideration

  • Maria Lehmann,
  • Annette B. Pfahlberg,
  • Henner Sandmann,
  • Wolfgang Uter and
  • Olaf Gefeller

Overexposure to ultraviolet (UV) radiation is the main modifiable risk factor for skin cancer. The Global Solar Ultraviolet Index (UVI) was introduced as a tool to visualize the intensity of UV radiation on a certain day, which should enable and enco...

  • Article
  • Open Access
449 Views
17 Pages

Thin, dry skin is characterized by impaired barrier integrity, loss of dermal density, and accelerated aging driven by intrinsic and extrinsic factors. Biomimetic collagen peptides mimic native collagen sequences, stimulating fibroblasts to enhance s...

  • Article
  • Open Access
3 Citations
2,313 Views
19 Pages

5 November 2024

Monte Carlo techniques have been extensively used for planning laser-based clinical procedures such as photobiomodulation. However, the effects of several biological tissue characteristics regarding its morphological structure and physiological param...

  • Article
  • Open Access
2 Citations
8,014 Views
12 Pages

1 September 2025

Fractional laser (FL) and fractional radiofrequency (FRF) are effective treatments for atrophic acne scars, yet comparative data in Asian populations with darker skin types remain limited. This retrospective cohort study compared the clinical effecti...

  • Article
  • Open Access
13,261 Views
12 Pages

14 October 2024

Inflammatory acne vulgaris (IAV) is a common skin condition characterized by the presence of reddish, inflamed, and painful lesions on the skin. IAV can drastically affect individuals, specifically their self-esteem, psychological health, and quality...

  • Article
  • Open Access
4 Citations
5,344 Views
9 Pages

Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study

  • Jessica Maloh,
  • Mincy Chakkalakal,
  • Fatima Sulaiman,
  • Waqas Burney,
  • Cindy J. Chambers and
  • Raja K. Sivamani

11 November 2022

External and internal stressors have been found to adversely affect skin health and overall wellness. There is growing interest in the use of anti-inflammatory and antioxidant plant-derived ingredients, such as ashwagandha, saffron, l-theanine, and t...

  • Article
  • Open Access
46 Citations
8,703 Views
14 Pages

Demographic Differences in Sun Protection Beliefs and Behavior: A Community-Based Study in Shanghai, China

  • Shuxian Yan,
  • Feng Xu,
  • Chunxue Yang,
  • Fei Li,
  • Jing Fan,
  • Linggao Wang,
  • Minqiang Cai,
  • Jianfeng Zhu,
  • Haidong Kan and
  • Jinhua Xu

Objective: We want to know the attitudes and behaviors towards UV protection and we want to analyze the difference between different Chinese demographic groups in this study. Methods: A community-based study was undertaken in Shanghai from October 20...

  • Communication
  • Open Access
5 Citations
18,919 Views
10 Pages

The use of low-fluence picosecond (LFPS) 1064 nm neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers, referred to as laser toning, is increasingly acknowledged as an effective treatment for pigmentation disorders in the Asian skin phenotype. This...

  • Article
  • Open Access
4 Citations
7,486 Views
10 Pages

Fractional Q-Switched 1064 nm Laser for Treatment of Atrophic Scars in Asian Skin

  • Steven Paul Nisticò,
  • Mario Sannino,
  • Gaia Fasano,
  • Miriam Marigliano,
  • Francesca Negosanti,
  • Luigi Bennardo and
  • Giovanni Cannarozzo

1 September 2022

Background and Objectives: Asian patients with Fitzpatrick skin type III–IV are a less studied subtype of patients in the medical literature. Q-Switched, 1064 nm neodymium-doped yttrium aluminum garnet (Nd: YAG) laser with a fractionated beam p...

  • Review
  • Open Access
16 Citations
18,233 Views
19 Pages

5 April 2024

The heightened awareness of ethnic dermatology aligns with the growing prevalence of skin of color communities globally, where hyperpigmentation disorders pose a common dermatological challenge. Effectively addressing dermal pigmentation is challengi...

  • Article
  • Open Access
1,186 Views
16 Pages

Sun Exposure and Behaviours in Saudi Arabia: A National Study of over Eleven Thousand Participants Utilising the Arabic Sun Exposure and Behaviour Inventory

  • Abdullah Aleisa,
  • Nasser M. AbuDujain,
  • Qais A. Almuhaideb,
  • Yazeed A. Alrodiman,
  • Hadeel F. AlMajid,
  • Turki N. AboSarhad,
  • Omnia A. Alali,
  • Anas M. Abudasir,
  • Dana Alkhudair and
  • Turky H. Almigbal
  • + 5 authors

26 November 2025

Background: Excessive sun exposure is a major modifiable risk factor for skin cancer, with ultraviolet (UV) radiation identified as a key contributor. Saudi Arabia’s high UV index and hot climate increase the risk of photo-induced skin damage a...

  • Article
  • Open Access
4 Citations
4,721 Views
11 Pages

Objectively-Assessed Ultraviolet Radiation Exposure and Sunburn Occurrence

  • Tammy K. Stump,
  • Suzanne Fastner,
  • Yeonjung Jo,
  • Jonathan Chipman,
  • Benjamin Haaland,
  • Elizabeth S. Nagelhout,
  • Ali P. Wankier,
  • Riley Lensink,
  • Angela Zhu and
  • Yelena P. Wu
  • + 2 authors

Ultraviolet radiation (UVR) exposure is the primary modifiable risk factor for melanoma. Wearable UVR sensors provide a means of quantifying UVR exposure objectively and with a lower burden than self-report measures used in most research. The purpose...

  • Article
  • Open Access
11 Citations
5,896 Views
13 Pages

Primary Localized Cutaneous Amyloidosis in Central Europe: A Retrospective Monocentric Study on Epidemiology and Therapy

  • Sára Pálla,
  • Enikő Kuroli,
  • Eszter Alexa Tóth,
  • Bernadett Hidvégi,
  • Péter Holló and
  • Márta Medvecz

14 December 2023

Amyloid deposits can be the cause of many chronic diseases. Primary localized cutaneous amyloidosis (PLCA) is a chronic dermatologic condition with amyloid deposits in the papillary dermis. The most common types of the keratinocyte-derived form of PL...

  • Article
  • Open Access
1,553 Views
16 Pages

Automatic Assessment of AK Stage Based on Dermatoscopic and HFUS Imaging—A Preliminary Study

  • Katarzyna Korecka,
  • Anna Slian,
  • Adriana Polańska,
  • Aleksandra Dańczak-Pazdrowska,
  • Ryszard Żaba and
  • Joanna Czajkowska

10 December 2024

Background: Actinic keratoses (AK) usually occur on sun-exposed areas in elderly patients with Fitzpatrick I–II skin types. Dermatoscopy and ultrasonography are two non-invasive tools helpful in examining clinically suspicious lesions. This stu...

  • Article
  • Open Access
498 Views
15 Pages

13 February 2026

Severe Dengue fever can cause Dengue Hemorrhagic Fever (DHF), a life-threatening condition characterized by plasma leakage and hemoconcentration. A hematocrit (Hct) rise of ≥20% is a key indicator for medical intervention, but current monitoring i...