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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Global Expert Views on Aortic Valve Repair and Replacement: 2nd Edition

edited by

Jose Alberto De Agustín

submission deadline 25 Oct 2025 | Viewed by 83 | Submission Open

Keywords: aortic valve pathologies; minimally invasive approach; aortic valve repair; aortic valve replacement; imaging techniques

(This special issue belongs to the Section Cardiovascular Medicine)

Management and Prognosis of Spinal Surgery

edited by Francesco Costa

submission deadline 25 Oct 2025 | Viewed by 80 | Submission Open

Keywords: spine; spinal surgery; spinal biomechanics; microneurosurgery; vertebral oncology

(This special issue belongs to the Section Clinical Neurology)

Novel Insights into Colorectal Surgery

edited by

Valentin Calu

submission deadline 25 Oct 2025 | Viewed by 79 | Submission Open

Keywords: colorectal surgery; robotic surgery; neoadjuvant treatment; minimally invasive techniques; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Oral and Maxillofacial Surgery: Current Advances and Future Directions

edited by Niedzielska Iwona

submission deadline 25 Oct 2025 | Viewed by 77 | Submission Open

Keywords: oral and maxillofacial surgery; reconstructive surgery; periodontitis; dental implants; maxillofacial deformities

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Oral Cancer: Clinical Updates and Perspectives

edited by

Jutta Ries

Mayte Buchbender

and

Ulrike Simone Speth

submission deadline 25 Oct 2025 | Viewed by 77 | Submission Open

Keywords: oral cancer; oral surgery; dental implant; tooth extraction; oral health; early detection; biomarkers; targeted therapy; immunotherapy

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Advances in Imaging and Interventional Techniques for Renal and Adrenal Diseases

edited by Francesco Ziglioli and Umberto Vittorio Maestroni

submission deadline 25 Oct 2025 | Viewed by 68 | Submission Open

Keywords: renal cancer; adrenal mass; robotic surgery; minimally invasive techniques; radiomics; tailored treatment

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Gastrointestinal Endoscopy

edited by

Ivan Žaja

and Željko Puljiz

submission deadline 25 Oct 2025 | Viewed by 62 | Submission Open

Keywords: endoscopy; polyps; EMR; ESD; POEM; balloon dilatation; coagulation; imaging; AI imaging

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Advances and Clinical Outcomes of Endocrinology

edited by Stefana Catalina Bilha and

Cristina Preda

submission deadline 25 Oct 2025 | Viewed by 62 | Submission Open

Keywords: endocrinology; obesity; metabolic and bone disease; chronic conditions

(This special issue belongs to the Section Endocrinology & Metabolism)

Pathophysiology of Hypertension and Related Diseases: 2nd Edition

edited by

Tomislav Bulum

and

Ingrid Prkačin

submission deadline 25 Oct 2025 | Viewed by 56 | Submission Open

Keywords: arterial hypertension; resistant hypertension; secondary hypertension; prevention and screening of hypertension; hypertensive crisis; treatment of hypertension; obstructive sleep apnea syndrome; pathophysiology of hypertension; hypertension and the environment; (pre)hypertension and genetics

(This special issue belongs to the Section Vascular Medicine)

New Concepts in Minimally Invasive Spine Surgery

edited by

Yi Lu

and Michael Y. Wang

submission deadline 25 Oct 2025 | Viewed by 40 | Submission Open

Keywords: minimally invasive spine surgery; image navigation; tubular retractor; endoscopic spine surgery; virtual and aug-mented reality; lateral spine surgery

(This special issue belongs to the Section Clinical Neurology)

Recent Advances in the Diagnosis and Treatment of Gastrointestinal Diseases

edited by

Ahamed Khalyfa

submission deadline 27 Oct 2025 | 3 articles | Viewed by 1709 | Submission Open

Keywords: advanced endoscopy; innovation in GI; pathophysiology of GI disorders; artificial intelligence in GI; gastrointestinal diseases

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Chronic Kidney Disease: Global Dimension and Perspectives

edited by Valentina Câmpean

submission deadline 28 Oct 2025 | 1 articles | Viewed by 520 | Submission Open

Keywords: histological changes; renal dysfunction; kidney diseases; glomerulonephritis; polycystic kidney disease; kidney failure; kidney cancer; atherosclerosis; heart disease; renal and renovascular hypertension

(This special issue belongs to the Section Nephrology & Urology)

Prostate Surgery: The Latest Advances and Future Trends

edited by Akhil K. Das and

Bruce Gao

submission deadline 28 Oct 2025 | Viewed by 112 | Submission Open

Keywords: benign prostatic hyperplasia (BPH); minimally invasive surgical therapies (MIST); laser enucleation (HoLEP; ThuLEP); Aquablation; Rezum; robotic prostatectomy; anatomic enucleation

(This special issue belongs to the Section Nephrology & Urology)

Symptoms and Treatment of Cardiac Amyloidosis

edited by Syed Bukhari

submission deadline 28 Oct 2025 | Viewed by 99 | Submission Open

Keywords: cardiac amyloidosis; transthyretin amyloidosis; light chain amyloidosis; cardiac magnetic resonance; echocardiography; nuclear scintigraphy; endomyocardial biopsy; gene silencers; transthyretin stabilizers; immunotherapy

(This special issue belongs to the Section Cardiology)

Recent Advances and Clinical Outcomes of Hip and Knee Arthroplasty

edited by

Andrea Volpin

submission deadline 28 Oct 2025 | Viewed by 69 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; joint replacement; clinical outcomes; surgical innovation; patient recovery; prosthetics; perioperative care

(This special issue belongs to the Section Orthopedics)

PET/CT Imaging in Oncology: Clinical Updates and Prospects

edited by Ahmad Shariftabrizi

submission deadline 28 Oct 2025 | Viewed by 52 | Submission Open

Keywords: new radiotracers; PET radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy outcome prediction; PET physics; normal tissue PET/CT; synchronous malignancies

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Diagnosis, Treatment, and Management of Gastrointestinal Oncology

edited by Toufic A. Kachaamy and Madappa N. Kundranda

submission deadline 30 Oct 2025 | 1 articles | Viewed by 7196 | Submission Open

Keywords: gastrointestinal oncology; endoscopic oncology; biliary tract cancer; colorectal cancer; esophageal cancer; stomach cancer

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Biomarkers and Lung Cancer: Clinical Application

edited by

Roberto Gasparri

submission deadline 30 Oct 2025 | 5 articles | Viewed by 4459 | Submission Open

Keywords: lung cancer; early diagnosis; prognosis; biomarkers; body fluids; liquid biopsy

(This special issue belongs to the Section Respiratory Medicine)

New Update on Personalized Treatment of Autism Spectrum Disorder and Related Disorders

edited by

Francesca Cucinotta

, Rosamaria Siracusano and Erica Pironti

submission deadline 30 Oct 2025 | 1 articles | Viewed by 3517 | Submission Open

Keywords: autism spectrum disorder; autism related disorders; children and adolescents; intervention strategies; therapeutic advance; new technologies; evidence-based practices

(This special issue belongs to the Section Mental Health)

Advances in Anesthesia for Cardiac Surgery

edited by Christopher M. Munch and

Pietro Giorgio Malvindi

submission deadline 30 Oct 2025 | 3 articles | Viewed by 3355 | Submission Open

Keywords: enhanced recovery after cardiac surgery (ERACS); minimally invasive cardiac surgery (MICS); ultra-fast-track an-esthesia; chest wall blocks in cardiac anesthesia; opioid-free anesthesia in cardiac surgery; neurologic dysfunction and cardiac surgery; pre- and posthabilitation in cardiac surgery

(This special issue belongs to the Section Anesthesiology)

Clinical Highlights in Chronic Obstructive Pulmonary Disease (COPD)

edited by

Richard Zuwallack

and Dimosthenis Lykouras

submission deadline 30 Oct 2025 | 3 articles | Viewed by 2328 | Submission Open

Keywords: COPD treatment; inhalers; patient-reported outcomes; COPD rehabilitation; cardiovascular risk

(This special issue belongs to the Section Respiratory Medicine)

New Advances in Minimally Invasive Surgery for Gynecologic Cancer

edited by

Rafał Watrowski

and

Valerio Gallotta

submission deadline 30 Oct 2025 | 1 articles | Viewed by 2089 | Submission Open

Keywords: minimally invasive surgery; gynecologic surgery; gynecologic oncology; surgical techniques; patient safety; personalized medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Facial Plastic and Cosmetic Medicine

edited by

Neelam Vashi

submission deadline 30 Oct 2025 | 1 articles | Viewed by 1447 | Submission Open

Keywords: cosmetics; aesthetics; plastic surgery; skin rejuvenation; beauty; procedures

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Challenges in High-Risk Pregnancy and Delivery

edited by

Salvatore Andrea Mastrolia

submission deadline 30 Oct 2025 | 1 articles | Viewed by 853 | Submission Open

Keywords: high-risk pregnancy; preeclampsia; cesarean section; maternal– fetal medicine; ultrasound; fetal monitoring; complications; delivery; placental abruption; great obstetrical syndromes

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Ocular Surface Research: Exploring Antimicrobial Resistance and Emerging Therapeutics

edited by

Francesco D'Oria

, Giovanni Alessio and Maria Gabriella la Tegola

submission deadline 30 Oct 2025 | 1 articles | Viewed by 424 | Submission Open

Keywords: ocular surface microbiome; antimicrobial resistance; ocular infections and therapeutics; novel diagnostics in ophthalmology; biofilms and pathogen evolution; infection control and public health

(This special issue belongs to the Section Ophthalmology)

Advances in Anesthesia and Intensive Care During Perioperative Period

edited by

Philipp Simon

submission deadline 30 Oct 2025 | 1 articles | Viewed by 423 | Submission Open

Keywords: general anesthesia; intensive care medicine; post intensive care syndrome; perioperative management; fast track; pain management; complications; postoperative outcome; digitalization; big data; AI; closed-loop systems; machine learning; clinical decision support; telemedicine

(This special issue belongs to the Section Intensive Care)

Advancements in Venous Thrombosis Management: From Prevention to Long-Term Care

edited by

Luca Costanzo

submission deadline 30 Oct 2025 | Viewed by 342 | Submission Open

Keywords: venous thromboembolism; post-thrombotic syndrome; direct oral anticoagulant; pulmonary embolism; thrombosis; factor xia inhibitors; thrombolysis; cancer; antiphospholipid syndrome; catheter-directed thrombolysis; inferior vena cava filters

(This special issue belongs to the Section Vascular Medicine)

Advancements and Challenges in Reconstructive Urology and Urethral Surgery

edited by

Francesco Chierigo

submission deadline 30 Oct 2025 | 1 articles | Viewed by 310 | Submission Open

Keywords: reconstructive urology; urethral surgery; urethroplasty; minimally invasive surgery; robotic-assisted surgery; urinary tract reconstruction; surgical innovation; patient-reported outcomes

(This special issue belongs to the Section Nephrology & Urology)

Advances in Gastroenterological Surgery

edited by Alan Biloslavo and Antonio La Greca

submission deadline 30 Oct 2025 | Viewed by 250 | Submission Open

Keywords: mini-invasive surgery; technology; artificial intelligence; negative pressure; indocyanine green; ultrasound; GE surgery; emergency surgery; precision surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Spine Surgery: Current Practice and Future Directions

edited by Claudio Bernucci and Francesco Costa

submission deadline 30 Oct 2025 | Viewed by 131 | Submission Open

Keywords: degenerative; spinal trauma; spine tumors; neurosurgery; spine surgery; spinal deformity; scoliosis; robotics surgery; spinal cord injury; clinical practices; regenerative therapies

(This special issue belongs to the Section Clinical Neurology)

Artificial Intelligence and Deep Learning in Medical Imaging

edited by Eros Montin and Giuseppe Carluccio

submission deadline 30 Oct 2025 | Viewed by 129 | Submission Open

Keywords: magnetic resonance imaging; radiomics; artificial intelligence (AI); deep learning; clinical and translational medicine; MRI safety; radiogenomics; multiomics

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Drug Therapy and Prognosis in Patients with Heart Failure

edited by

Manuel Méndez-Bailón

submission deadline 30 Oct 2025 | Viewed by 126 | Submission Open

Keywords: heart failure; drug therapy; prognosis; pharmacological innovations; cardiovascular outcomes; personalized medicine; heart failure management

(This special issue belongs to the Section Cardiology)

Innovations in Perioperative Anesthesia and Intensive Care

edited by

Ivan Gornik

and Ileana Lulic

submission deadline 30 Oct 2025 | Viewed by 122 | Submission Open

Keywords: perioperative anesthesia; intensive care; artificial intelligence in anesthesia; precision medicine in perioperative care; hemodynamic monitoring; multimodal analgesia; opioid-free anesthesia; ventilation strategies in ICU and surgery; neuromonitoring and sedation; perioperative resuscitation and ECMO

(This special issue belongs to the Section Intensive Care)

Clinical Update on Thoracic Trauma

edited by

Duilio Divisi

submission deadline 30 Oct 2025 | Viewed by 113 | Submission Open

Keywords: flail chest; isolated sternal fractures; manubrio-sternal dislocation; pneumothorax; hemothorax; thoracic aortic injury; heart and pulmonary vessels lesion; intercostal artery injury; diaphragm rupture; thoracoabdominal hernia; chylothorax; esophageal perforation

(This special issue belongs to the Section Respiratory Medicine)

Prosthetic Joint Infections: Contemporary Insights into Their Management and Prevention

edited by

Sebastian Scheidt

and Uwe Maus

submission deadline 30 Oct 2025 | Viewed by 112 | Submission Open

Keywords: arthroplasty; infection; replacement; antibiotics; management; hip; knee; shoulder; periprosthetic; prevention; implant retention; procedure; implant retention; debridement; cellular infection; infection markers

(This special issue belongs to the Section Orthopedics)

Catheter Ablation of Atrial Fibrillation: Current Progress and New Challenges

edited by Sorin Stefan Popescu, Roland Richard Tilz and Karl-Heinz Kuck

submission deadline 30 Oct 2025 | Viewed by 100 | Submission Open

Keywords: atrial fibrillation; novel technologies; pulmonary vein isolation; same-day discharge; pulsed field ablation; cryo-ablation; radiofrequency; safety; efficacy; sustainability

(This special issue belongs to the Section Cardiology)

Advances in Atrial Fibrillation Treatment

edited by Iwona Woźniak-Skowerska

submission deadline 30 Oct 2025 | Viewed by 86 | Submission Open

Keywords: pulmonary vein ablation; atrial fibrillation; heart failure; arrhythmia; personalized medicine

(This special issue belongs to the Section Cardiovascular Medicine)

Novel Insights into Clinical Diagnosis and Management of Degenerative Cervical Myelopathy

edited by

Carlo Brembilla

, Francesco Costa and Filippo Maria Polli

submission deadline 30 Oct 2025 | Viewed by 81 | Submission Open

Keywords: degenerative cervical myelopathy (DCM); cervical spondylotic myelopathy (CSM); cervical spinal stenosis; cervical cord compression; MRI of the cervical spine; cervical spine surgery; physical therapy; rehabilitation; ossification of the posterior longitudinal ligament (OPLL); cervical deformity (e.g.; kyphosis and lordosis); patient-reported out-comes; surgical outcome prediction

(This special issue belongs to the Section Clinical Neurology)

Prostatectomy: Clinical Updates and Perspectives

edited by Antonio Nacchia

submission deadline 30 Oct 2025 | Viewed by 67 | Submission Open

Keywords: single port; prostatectomy; robotics; RARP; prostate cancer

(This special issue belongs to the Section Nephrology & Urology)

Myeloproliferative Neoplasms (MPN): Recent Advances, Current Practices and Future Perspectives

edited by Arumugam Manoharan

submission deadline 31 Oct 2025 | 7 articles | Viewed by 11253 | Submission Open

Keywords: diagnosis; pathogenesis; prognosis; thromboprophylaxis; treatment

(This special issue belongs to the Section Hematology)

Progress in Patient Safety and Quality in Maternal–Fetal Medicine

edited by Samuel T. Bauer

submission deadline 31 Oct 2025 | 5 articles | Viewed by 8063 | Submission Open

Keywords: maternal– fetal medicine; pregnancy; postpartum; medical error; maternity; fetus

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Advances in Endodontics and Dental Traumatology

edited by Karin Christine Huth

submission deadline 31 Oct 2025 | 6 articles | Viewed by 3454 | Submission Open

Keywords: endodontology; traumatology; regeneration; biocompatibility; dental materials; antimicrobial; dynamic and static navigation in endodontics; under- and postgraduate education in endodontology and traumatology; artificial intelligence; autotransplantation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Innovations and Challenges in Clinical Toxicology and Therapeutic Drug Monitoring

edited by Zhicheng Jin

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2749 | Submission Open

Keywords: toxicology screen; therapeutic drug monitoring; mass spectrometry; immunoassays; pain management; opioids

(This special issue belongs to the Section Pharmacology)

Chronic Renal Disease: Diagnosis, Treatment, and Management

edited by

Anna Clementi

submission deadline 31 Oct 2025 | 3 articles | Viewed by 1353 | Submission Open

Keywords: acute kidney injury; chronic kidney disease; cardio– renal syndromes; clinical nephrology; diagnosis and management

(This special issue belongs to the Section Nephrology & Urology)

Youth Sports Injuries: From Prevalence to Prevention

edited by Swarup Mukherjee and

Gregory C. Bogdanis

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1171 | Submission Open

Keywords: youth sports injuries; musculoskeletal injuries; injury prevention; sport safety; youth athletes

(This special issue belongs to the Section Sports Medicine)

Clinical Management of Oral Healthcare in Diverse Patient Populations: Second Edition

edited by

Antonella Polimeni

and

Iole Vozza

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1160 | Submission Open

Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Advances in Procedures for the Diagnosis and Treatment of Cardiovascular Disease

edited by

Alexandru Burlacu

and

Adrian Covic

submission deadline 31 Oct 2025 | Viewed by 1158 | Submission Open

Keywords: cardiovascular disease; diagnostic procedures; therapeutic advancements; minimally invasive interventions; precision medicine; imaging technologies; catheter-based treatments; translational research; interventional cardiology; clinical innovations

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Care and Rehabilitation for Neuromuscular Diseases

edited by

Hans-Jürgen Gdynia

submission deadline 31 Oct 2025 | Viewed by 714 | Submission Open

Keywords: neuromuscular diseases; myopathy; neuropathy; motor neuron disease; amyotrophic lateral sclerosis; diseases of neuromuscular junction; neurorehabilitation; rehabilitation; clinical care; neuroscience

(This special issue belongs to the Section Clinical Rehabilitation)

Cardiogenic Shock and Cardiac Arrest: Updates, Challenges and Opportunities

edited by Torben K. Becker

submission deadline 31 Oct 2025 | 1 articles | Viewed by 572 | Submission Open

Keywords: cardiac arrest; extracorporeal membrane oxygenation; extracorporeal CPR; cardiopulmonary resuscitation; cardiogenic shock; resuscitation; prognostication

(This special issue belongs to the Section Cardiology)

New Perspective of Oral and Maxillo-Facial Surgery

edited by

Valentino Vellone

Umberto Committeri

and Alessandra Lucchese

submission deadline 31 Oct 2025 | 1 articles | Viewed by 500 | Submission Open

Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Displaying special issue 1001-1050 on page 21 of 27.

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