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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Plastic Surgery: Challenges and Future Directions

edited by Philip Brazio and Edward C. Ray

submission deadline 20 Jan 2026 | 1 articles | Viewed by 2306 | Submission Open

Keywords: plastic surgery; reconstructive surgery; esthetic surgery; innovation; challenges; technology

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Application of Radiotherapy in Modern Oncology

edited by

Lukas Käsmann

and

Fabian Weykamp

submission deadline 20 Jan 2026 | 2 articles | Viewed by 2209 | Submission Open

Keywords: brain metastasis; bone metastasis; brain tumors; head and neck cancers; thoracic oncology; breast cancer; prostate cancer; sarcoma

(This special issue belongs to the Section Oncology)

Recent Clinical Research on Nonalcoholic Fatty Liver Disease: 2nd Edition

edited by Gerond V. Lake-Bakaar

submission deadline 20 Jan 2026 | 2 articles | Viewed by 2029 | Submission Open

Keywords: NAFLD; NASH; cirrhosis; hepatocellular carcinoma; hepatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Sports Injuries: Recent Advances in Prevention and Rehabilitation, 2nd Edition

edited by

Stasinopoulos Dimitrios

submission deadline 20 Jan 2026 | 2 articles | Viewed by 2004 | Submission Open

Keywords: sports injuries; treatment; musculoskeletal disorders; rehabilitation; physical rehabilitation; exercise science; sports science; injury prevention

(This special issue belongs to the Section Sports Medicine)

Hip Fracture and Surgery: Clinical Updates and Challenges

edited by

Norio Imai

submission deadline 20 Jan 2026 | 3 articles | Viewed by 1750 | Submission Open

Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty

(This special issue belongs to the Section Orthopedics)

Long COVID and Cardiovascular Health: Clinical Perspectives on Risk and Management

edited by Mariana Tudoran and

Cristina Tudoran

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1719 | Submission Open

Keywords: long COVID; cardiovascular disease; long COVID therapy; management of long COVID; mechanisms of long COVID

(This special issue belongs to the Section Cardiovascular Medicine)

Sustaining Success Through Innovation in Kidney Transplantation

edited by Junji Uchida

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1654 | Submission Open

Keywords: kidney transplantation; long-term graft survival; immunosuppression; organ shortage; post-transplant complication

(This special issue belongs to the Section Nephrology & Urology)

Eating Disorders: Current Epidemiology and Advances in Diagnosis and Treatment—Second Edition

edited by

Arthur Eumann Mesas

submission deadline 20 Jan 2026 | 3 articles | Viewed by 1650 | Submission Open

Keywords: eating disorder; bulimia nervosa; anorexia nervosa; binge eating disorder; sociocultural context; epidemiology; di-agnosis; treatment; prevention

(This special issue belongs to the Section Mental Health)

Microsurgery: Current and Future Challenges

edited by

Matthias Aitzetmüller-Klietz

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1630 | Submission Open

Keywords: microsurgery; reconstruction; reconstructive surgery; breast reconstruction; extremity reconstruction

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Current Situation and Challenges of Endovascular Treatment Strategies for Acute Ischemic Stroke

edited by

Fusao Ikawa

submission deadline 20 Jan 2026 | 1 articles | Viewed by 1507 | Submission Open

Keywords: acute ischemic stroke; endovascular treatment; imaging; management of ischemic stroke; system and strategy for acute ischemic stroke; multidisciplinary approach for acute ischemic stroke

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Autoimmune Disorders

edited by

Chiara Pellicano

and

Edoardo Rosato

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1364 | Submission Open

Keywords: systemic sclerosis; Raynaud’ s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis

(This special issue belongs to the Section Immunology)

Allergen-Specific Immunotherapy (AIT) for Allergic Diseases of the Respiratory Tract and Food Allergies

edited by

Ralph Mösges

submission deadline 20 Jan 2026 | 1 articles | Viewed by 1280 | Submission Open

Keywords: allergy; allergic rhinitis; allergic conjunctivitis; allergic asthma; food allergy; peptide immunotherapy; allergoids; SLIT; SCIT; OIT

(This special issue belongs to the Section Immunology)

Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition

edited by Jaime A. Hernández-Montfort

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1264 | Submission Open

Keywords: cardiogenic shock; cardiac arrest; temporary mechanical circulatory support; ECMO; transitions; heart recovery; heart replacement

(This special issue belongs to the Section Cardiology)

Advances in Tuberculosis: Comprehensive Insights and Management Strategies

edited by Aliaksandr Skrahin

submission deadline 20 Jan 2026 | 1 articles | Viewed by 1134 | Submission Open

Keywords: pulmonary and extra-pulmonary tuberculosis (TB); TB epidemiology; TB screening; TB prevention; TB diagnostics; TB treatment; TB co-infections (e.g.; HIV; Hepatitis B and C); TB co-morbidities (e.g.; diabetes); host and Mycobacteria genetic; molecular mechanisms and genotype/phenotype correlations

(This special issue belongs to the Section Infectious Diseases)

Endodontic Disease: Prevalence, Risk Factors, and Treatment Outcome

edited by

Razvan Ionut Ghinea

Ioana-Sofia Pop-Ciutrilă

and

Luminita-Maria Nica

submission deadline 20 Jan 2026 | 2 articles | Viewed by 976 | Submission Open

Keywords: endodontics; apical periodontitis; pulpitis; root canal treatment; risk factors; treatment outcomes; regenerative endodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances and Trends in Pediatric Surgery

edited by

Nikolaos Zavras

and

Anastasia Dimopoulou

submission deadline 20 Jan 2026 | 1 articles | Viewed by 903 | Submission Open

Keywords: pediatric surgery; minimally invasive surgery; robotics; trends; advances

(This special issue belongs to the Section Clinical Pediatrics)

Emerging Treatment Options in Inflammatory Bowel Disease

edited by

Sandro Ardizzone

and Roberta Maselli

submission deadline 20 Jan 2026 | 1 articles | Viewed by 698 | Submission Open

Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; biologics; small molecule therapies; personalized medicine; therapeutic drug monitoring; immunology; gut microbiome; clinical practice; endoscopic mucosal resection (EMR); endoscopic submucosal dissection (ESD); endoscopic balloon dilation and endoscopic stent placement; chromoendoscopy; confocal laser endomicroscopy; artificial intelligence

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Insights into Pediatric Critical Care

edited by Katherine Biagas and Daniel E Sloniewsky

submission deadline 20 Jan 2026 | 1 articles | Viewed by 696 | Submission Open

Keywords: PICU; anemia; blood transfusion; critically ill children; traumatic hemorrhage

(This special issue belongs to the Section Intensive Care)

New Perspectives in Chronic Kidney Disease, Transplantation and Immune System

edited by

Maria Daoudaki

and Dimitrios A. Tsakiris

submission deadline 20 Jan 2026 | 1 articles | Viewed by 659 | Submission Open

Keywords: kidney transplantation; HLA; matching at the epitope level; DSAs; complement; kidney disease epigenetics; diabetic nephropathy; hemostasis; graft rejection; B and T cell immunophenotyping; end stage renal disease

(This special issue belongs to the Section Nephrology & Urology)

Advancements in the Treatment of Myeloproliferative Neoplasms and Myelodysplastic Syndromes

edited by Ivan Krečak, Marko Skelin and Zinaida Perić

submission deadline 20 Jan 2026 | 1 articles | Viewed by 558 | Submission Open

Keywords: myeloproliferative neoplasms; myelodysplastic syndromes; treatment; risk stratification; prognosis

(This special issue belongs to the Section Hematology)

Current Practice and Future Perspectives on Laryngeal Surgery

edited by

Eugenia Allegra

and

Maria Rita Bianco

submission deadline 20 Jan 2026 | 1 articles | Viewed by 503 | Submission Open

Keywords: laryngeal disorders; laryngeal surgery; microsurgery; endoscopic surgery; open surgery; laser surgery

(This special issue belongs to the Section Otolaryngology)

Endometriosis: Diagnosis and Treatment

edited by

Camran R. Nezhat

and

Ceana Nezhat

submission deadline 20 Jan 2026 | 1 articles | Viewed by 501 | Submission Open

Keywords: endometriosis; diagnosis; video laparoscopy with and without robotic assistance; chronic pelvic pain; fertility preservation; minimally invasive surgery; biomarkers; artificial intelligence in endometriosis; adenomyosis; and adenomyoma care; multidisciplinary care; personalized medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in the Treatment of Glaucoma and Ocular Hypertension

edited by Ahnul Ha

submission deadline 20 Jan 2026 | 1 articles | Viewed by 497 | Submission Open

Keywords: glaucoma; ocular hypertension; intraocular pressure (IOP); minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI); neuroprotection; meta-analysis

(This special issue belongs to the Section Ophthalmology)

Glaucoma Surgery: Current Challenges and Future Perspectives

edited by

Tina Tzee Ling Wong

and

Esther M. Hoffmann

submission deadline 20 Jan 2026 | 1 articles | Viewed by 450 | Submission Open

Keywords: glaucoma; filtration surgery; trabeculectomy; MIGS; scarring; anti-metabolites; wound healing; anti-fibrotics

(This special issue belongs to the Section Ophthalmology)

Clinical Comparisons of Nonpharmaceutical and Pharmaceutical Analgesia

edited by

Sang Hun Kim

and

Yoon Ji Choi

submission deadline 20 Jan 2026 | Viewed by 272 | Submission Open

Keywords: acute pain; chronic pain; postoperative pain; non-pharmaceutical; pharmaceutical; analgesia; clinical

(This special issue belongs to the Section Anesthesiology)

Beyond the Kidney: Managing Chronic Kidney Disease in the Era of Cardio-Metabolic-Kidney Syndrome

edited by

Maria Amicone

and

Antonio Pisani

submission deadline 20 Jan 2026 | Viewed by 236 | Submission Open

Keywords: chronic kidney disease; disease-modifying therapy; physical exercise; cardio-metabolic-kidney syndrome; SGLT2 in-hibitors; MRA; renal nutrition; innovative therapies; low protein diet

(This special issue belongs to the Section Nephrology & Urology)

Metabolic Dysregulation Across the Spectrum from Anorexia Nervosa to Obesity

edited by Andriana C. Kaliora

submission deadline 20 Jan 2026 | Viewed by 213 | Submission Open

Keywords: metabolic dysregulation; anorexia nervosa; obesity; environmental factors in metabolic health; gut microbiota and metabolism; hormonal regulation of appetite; inflammation and metabolic disorders; dietary influence on metabolism

(This special issue belongs to the Section Endocrinology & Metabolism)

Advanced Diagnostic and Therapeutic Strategies for Sarcoidosis

edited by

Małgorzata Sobiecka

and

Monika Szturmowicz

submission deadline 20 Jan 2026 | Viewed by 207 | Submission Open

Keywords: sarcoidosis; cardiac sarcoidosis; pulmonary fibrosis; magnetic resonance imaging; FDG-PET/CT; echocardiography; neurosarcoidosis; differential diagnosis; hypercalcaemia; IGRA; sarcoidosis-associated pulmonary hypertension; fatigue; corticosteroids; metotrexat; infliximab; antifibrotic treatment; lung transplantation; artificial intelligence; broncho-alveolar lavage; cytokines

(This special issue belongs to the Section Respiratory Medicine)

Multiple Myeloma: Therapeutic and Management Strategies

edited by Terri Parker

submission deadline 20 Jan 2026 | Viewed by 206 | Submission Open

Keywords: multiple myeloma; frontline treatment; monoclonal antibodies; sequencing of treatment; immunotherapy; CAR T; Bi-specific T cell engagers; toxicity management

(This special issue belongs to the Section Hematology)

Idiopathic Pulmonary Fibrosis (IPF): Current Perspectives and Future Directions

edited by Vito D’Agnano

submission deadline 20 Jan 2026 | Viewed by 195 | Submission Open

Keywords: pulmonary fibrosis; IPF; ILD; antifibrotics; EMT; respiratory physiology; metabolism

(This special issue belongs to the Section Respiratory Medicine)

Artificial Intelligence (AI) and Deep Learning (DL) in Medical Imaging

edited by

Francesco Pucciarelli

submission deadline 20 Jan 2026 | Viewed by 149 | Submission Open

Keywords: artificial intelligence; deep learning; imaging; diagnosis; precision medicine; oncologic

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Artificial Intelligence (AI) in Dental Clinical Practice

edited by

Eiji Tanaka

and Keiichiro Watanabe

submission deadline 20 Jan 2026 | Viewed by 145 | Submission Open

Keywords: artificial intelligence; dental diagnostics; machine learning; deep learning; digital dentistry; clinical decision support; diagnostic automation; data transparency; evidence-based dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Innovations and Evolution of Extracorporeal Organ Support in Critical Care

edited by

Francesco Alessandri

Giovanni Giordano

and Antonella Tosi

submission deadline 20 Jan 2026 | Viewed by 143 | Submission Open

Keywords: critical care; extracorporeal organ support; critical care nephrology; cardiology; ARDS; sepsis; blood purification; liver support

(This special issue belongs to the Section Intensive Care)

Sarcopenia Across the Lifespan: Risk Factors, Mechanisms, and Management in Aging and Disease

edited by

Juan Mielgo-Ayuso

and

Natalia Busto

submission deadline 20 Jan 2026 | Viewed by 113 | Submission Open

Keywords: sarcopenia; aging; chronic disease; risk factors; muscle physiology; prevention; nutrition; exercise; treatment strategies

(This special issue belongs to the Section Orthopedics)

Cardiopulmonary Resuscitation in the Emergency Care Unit

edited by

Martín Otero-Agra

, Felipe Fernández-Méndez,

Myriam Santos-Folgar

and

María Fernández-Méndez

submission deadline 20 Jan 2026 | Viewed by 112 | Submission Open

Keywords: cardiopulmonary resuscitation; advanced life support; new technologies; special circumstances; emergency care unit

(This special issue belongs to the Section Emergency Medicine)

Innovations in Infertility Treatment and Assisted Reproductive Technologies (ARTs)

edited by Diana Alecsandru

submission deadline 20 Jan 2026 | Viewed by 112 | Submission Open

Keywords: infertility; assisted reproductive technology (ARTs); fertility preservation; in vitro fertilization (IVF); reproductive endocrinology

(This special issue belongs to the Section Obstetrics & Gynecology)

Acute Myocardial Infarction: Diagnosis, Treatment, and Rehabilitation

edited by

Francesca Giordana

submission deadline 20 Jan 2026 | Viewed by 104 | Submission Open

Keywords: acute myocardial infarction; coronary angioplasty; acute heart failure; cardiogenic shock; rehabilitation programs

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights in Trauma and Emergency Surgery

edited by Kai Oliver Jensen and Valentin Neuhaus

submission deadline 20 Jan 2026 | Viewed by 97 | Submission Open

Keywords: trauma and emergency surgery; multiple trauma; orthopedic trauma; surgery; concepts in trauma

(This special issue belongs to the Section Emergency Medicine)

Cardiac and Pulmonary Involvements in High-Risk Neonatal Cohorts: Short- and Long-Term Issues

edited by Arvind Sehgal

submission deadline 20 Jan 2026 | Viewed by 93 | Submission Open

Keywords: fetal growth restriction; lung disease; cardiac maladaptation; placenta; public health; neurodevelopment; long term; adulthood; Barker’ s hypothesis; newborn; vascular

(This special issue belongs to the Section Clinical Pediatrics)

Preventive Strategies and Novel Treatments for Rheumatoid Arthritis

edited by

Vincent Goeb

submission deadline 20 Jan 2026 | Viewed by 88 | Submission Open

Keywords: rheumatoid arthritis; antibodies; biologics; JAK; environment; susceptibility; therapeutic strategies

(This special issue belongs to the Section Immunology)

Bronchoscopy and Interventional Pulmonology

edited by Bryan S. Benn and

Jonathan Kurman

submission deadline 20 Jan 2026 | Viewed by 83 | Submission Open

Keywords: navigation-guided bronchoscopy; Robotic-guided bronchoscopy; 3D imaging integration; lung nodule/peripheral pulmonary lesion marking; transbronchial lung cryobiopsy and interstitial lung disease; malignant and benign central airway obstruction and stenosis; airway stents; pleuroscopic procedures; bronchoscopic lung volume reduction

(This special issue belongs to the Section Respiratory Medicine)

Clinical Updates and Current Challenges in Obstetrical Anesthesia

edited by Michael Froelich

submission deadline 20 Jan 2026 | Viewed by 82 | Submission Open

Keywords: obstetrical anesthesia; clinical innovation; practice guidelines; neuraxial techniques; enhanced recovery; risk stratification; maternal safety; multimodal analgesia; health systems innovation; global and low-resource care

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Prenatal Diagnosis and Fetal Therapy

edited by

Mar Bennasar

submission deadline 20 Jan 2026 | Viewed by 81 | Submission Open

Keywords: prenatal diagnosis; fetal therapy; genetic screening; non-invasive testing; fetal surgery; imaging technologies; high-risk pregnancies; in utero treatments; stem cell therapies; clinical innovations

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Application of Echocardiography in Heart Disease: 2nd Edition

edited by

Carlos Cotrim

submission deadline 20 Jan 2026 | Viewed by 76 | Submission Open

Keywords: transthoracic echocardiography; transesophageal echocardiography; stress echocardiography; valve disease; coronary artery disease; myocardial disease; pericardial disease; aortic disease; congenital heart disease

(This special issue belongs to the Section Cardiology)

Rehabilitation and Treatment of Post-COVID-19 Condition

edited by

Indre Bileviciute-Ljungar

submission deadline 20 Jan 2026 | Viewed by 72 | Submission Open

Keywords: post-COVID-19 condition; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); comorbidities; interdisciplinary; multimodal; digital medicine; rehabilitation; treatment; health-related quality of life; disability; return to work

(This special issue belongs to the Section Clinical Rehabilitation)

Current Status and Future of Urological Surgery

edited by

Filippo Marino

, Davide De Marchi and

Luca Di Gianfrancesco

submission deadline 20 Jan 2026 | Viewed by 72 | Submission Open

Keywords: urological surgery; robotic-assisted surgery; minimally invasive surgery; artificial intelligence; augmented reality; surgical navigation; endourology; laparoscopic urology; reconstructive urology; functional urology; bph treatment; urinary incontinence; prostate cancer surgery; bladder cancer surgery; surgical innovation; digital surgery

(This special issue belongs to the Section Nephrology & Urology)

Lung Transplantation: Current Challenges and New Perspectives

edited by Reinaldo E. Rampolla and Pedro A. Catarino

submission deadline 20 Jan 2026 | Viewed by 70 | Submission Open

Keywords: lung transplantation; interstitial lung diseases; pulmonary hypertension; chronic obstructive pulmonary disease; bronchiectasis; extra corporeal membrane oxygenation; robotic lung transplantation

(This special issue belongs to the Section Respiratory Medicine)

Emerging Trends in Multiple Myeloma

edited by

Despina Fotiou

submission deadline 20 Jan 2026 | Viewed by 69 | Submission Open

Keywords: multiple myeloma; personalized medicine; high-risk disease; cellular therapies; refractory disease

(This special issue belongs to the Section Hematology)

Recent Management of Hip Fractures

edited by

Toshiyuki Kawai

submission deadline 20 Jan 2026 | Viewed by 69 | Submission Open

Keywords: hip fracture; internal fixation; hemiarthroplasty; arthroplasty and fixation; osteoporosis management; fracture prevention; multidisciplinary care; surgical treatment; rehabilitation strategies

(This special issue belongs to the Section Orthopedics)

Insights and Innovations in Sports Cardiology

edited by

Garyfallia K. Pepera

submission deadline 20 Jan 2026 | Viewed by 68 | Submission Open

Keywords: sports cardiology; athlete heart; cardiovascular screening; arrhythmias; sudden cardiac death; cardiac rehabilitation; exercise prescription; mobile health; preventive cardiology; personalized medicine; pediatric fitness

(This special issue belongs to the Section Sports Medicine)

Displaying special issue 1001-1050 on page 21 of 30.

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