Cardiac and Pulmonary Involvements in High-Risk Neonatal Cohorts: Short- and Long-Term Issues

Dear Colleagues,

Thousands of infants are born every year who have been affected by fetal growth restriction. Growth restriction, when accompanied by prematurity, places the cohorts at a particular risk of adverse outcomes. Common underlying features include pre-eclampsia and utero-placental insufficiency. There is a growing body of evidence that notes echocardiographic and biochemical evidence of sub-clinical cardiac dysfunction. There are increasing concerns about the impact of growth restriction on respiratory and neurodevelopmental outcomes. Cardiovascular implications continue well into adulthood with higher rates of hypertension, stroke, and myocardial infarction. And yet, perinatal history is never asked when adults present with cardiac problems.

Pregnancy seems to have become the new frontline for developments where therapeutic options, whether pharmacological or non-pharmacological, are being explored. Some data on the Mediterraneandiet and mindfulness, as well as the use of sidenafel and cardiac modulators, appears to be promising.

In this Special Issue, we welcome authors to submit papers on clinical advances in all relevant domains related to fetal growth restriction. This can pertain to the antenatal period, the placenta, postnatal (cardiac, pulmonary, neurodevelopmental) as well as pediatric health, and adolescent and adult clinical research.

We invite the submission of original research, commentaries, and review articles. Research in progress with promising preliminary results will also be considered.

Prof. Dr. Arvind Sehgal
Guest Editor

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