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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Advances in Uterus and Ovarian Transplantation: 2nd Edition

edited by

Elliott G. Richards

submission deadline 20 Nov 2025 | Viewed by 201 | Submission Open

Keywords: uterus transplantation; gynaecological surgery; endometriosis; IVF; fibroids; reproductive medicine; laparoscopic surgery; assisted reproductive technology; reproductive endocrinology

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Therapeutic and Management Strategies of Epilepsy—Social and Neuropsychological Aspects

edited by

Hideaki Kanemura

submission deadline 20 Nov 2025 | Viewed by 196 | Submission Open

Keywords: quality of life (QOL); cognition; behavior; stigma; seizure severity; interictal epileptiform discharge (IED); social

(This special issue belongs to the Section Clinical Neurology)

State-of-the-Art Research on Thoracic Surgery

edited by

Russell Seth Martins

submission deadline 20 Nov 2025 | Viewed by 162 | Submission Open

Keywords: 3D imaging; surgical process optimization; robotic surgery; immunotherapy and targeted therapy; novel cancer detection methods; personalized treatment

(This special issue belongs to the Section General Surgery)

Minimally Invasive Techniques in Digestive Pathologies

edited by

Octavian Andronic

submission deadline 20 Nov 2025 | Viewed by 88 | Submission Open

Keywords: minimally invasive surgery; laparoscopic techniques; robotic surgery; endoscopic interventions; hybrid surgical approaches; digestive oncology; AI in surgery; surgical innovation; gastrointestinal disorders

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Pulmonary Hypertension and Idiopathic Pulmonary Fibrosis

edited by

Roberto Carbone

submission deadline 20 Nov 2025 | Viewed by 74 | Submission Open

Keywords: pulmonary hypertension; interstitial lung disease; idiopathic pulmonary fibrosis; heart failure; mitral valve disease

(This special issue belongs to the Section Respiratory Medicine)

Advances in Retinal Diseases—Mechanisms, Diagnostics, and Emerging Therapies

edited by

Minzhong Yu

submission deadline 20 Nov 2025 | Viewed by 73 | Submission Open

Keywords: inherited retinal diseases; age-related macular degeneration; diabetic retinopathy; multimodal retinal imaging; treatment

(This special issue belongs to the Section Ophthalmology)

Research Progress in Pediatric Endocrinology

edited by

Federico Baronio

submission deadline 20 Nov 2025 | Viewed by 65 | Submission Open

Keywords: pediatric endocrinology; rare endocrine disorders; precision medicine; congenital adrenal hyperplasia (CAH); short stature genetics; severe childhood obesity; glp-1 receptor agonists; endocrine disruptors; artificial intelligence (AI) in endocrinology; newborn screening

(This special issue belongs to the Section Clinical Pediatrics)

New Therapies for Diabetic Foot Ulcer Management

edited by

Irene Sanz-Corbalan

and

Raúl J. Molines Barroso

submission deadline 20 Nov 2025 | Viewed by 61 | Submission Open

Keywords: diabetic foot disease; diabetic foot ulcers; wound healing; biomarkers; telemedicine; artificial intelligence; preven-tive strategies; advanced therapies; amputation prevention; diabetes complications; novel treatments

(This special issue belongs to the Section Endocrinology & Metabolism)

Cardiac MRI: Current Techniques and Future Directions

edited by

Édouard Gerbaud

submission deadline 20 Nov 2025 | Viewed by 48 | Submission Open

Keywords: cardiac magnetic resonance imaging; technology; sequences; applications; acute coronary syndrome; intravascular imaging; CT-scanner

(This special issue belongs to the Section Cardiology)

Targeted Diagnosis and Treatment of Shoulder and Elbow Disease: 2nd Edition

edited by

Teresa Paolucci

and

Massimiliano Mangone

submission deadline 20 Nov 2025 | Viewed by 48 | Submission Open

Keywords: anterolateral deltoid split; joint pain; axillary nerve injury; rotator cuff injuries; shoulder arthroplasty; shoulder impingement syndrome; proximal humeral fracture; rehabilitation; exercise; physiotherapy; rehabilitative relapses

(This special issue belongs to the Section Orthopedics)

Acute Ischemic Stroke Management Strategies

edited by

Marta Iacobucci

submission deadline 20 Nov 2025 | Viewed by 48 | Submission Open

Keywords: mechanical thrombectomy; leptomeningeal collateral circulation; neuroprotection; reperfusion injury; ischemic penumbra

(This special issue belongs to the Section Clinical Neurology)

Clinical Research in Management of Corneal Diseases

edited by Massimo Busin and Angeli Christy Yu

submission deadline 20 Nov 2025 | Viewed by 42 | Submission Open

Keywords: corneal surgery; corneal transplant; lamellar keratoplasty; deep anterior lamellar keratoplasty; descemet membrane endothelial keratoplasty; descemet stripping automated endothelial keratoplasty; corneal neurotization

(This special issue belongs to the Section Ophthalmology)

Diagnosis and Treatment of Ocular Surface Diseases

edited by

Stuti Misra

and

Sònia Travé-Huarte

submission deadline 20 Nov 2025 | Viewed by 42 | Submission Open

Keywords: dry eye disease; ocular surface; anterior segment imaging; biomarkers; artificial intelligence; diagnostic tools; novel therapeutic agents; anterior eye care

(This special issue belongs to the Section Ophthalmology)

Novel Approaches in Cataract and Refractive Surgery

edited by Stephen T. Armenti

submission deadline 20 Nov 2025 | Viewed by 40 | Submission Open

Keywords: cataract surgery; complex cataract surgery; secondary intraocular lens surgery; refractive surgery (LASIK; PRK; SMILE); astigmatism correction; multifocal intraocular lenses; femtosecond laser; dropless cataract surgery

(This special issue belongs to the Section Ophthalmology)

Skin Wound Healing: Clinical Updates and Perspectives

edited by

András Bánvölgyi

and Norbert Kiss

submission deadline 20 Nov 2025 | Viewed by 39 | Submission Open

Keywords: dermatology; wound care; diagnosis; biomaterials; negative pressure wound therapy

(This special issue belongs to the Section Dermatology)

High-Risk Neuroblastoma and Rhabdoid Tumors: New Clinical Insights and Challenges (Second Edition)

edited by

Rupert Handgretinger

and Johannes Hubertus Schulte

submission deadline 20 Nov 2025 | Viewed by 39 | Submission Open

Keywords: neuroblastoma; rhabdoid tumor; autologous stem cell transplantation; allogeneic stem cell transplantation immunotherapy; anti-GD2 antibody; targeted therapy; CAR T-cells

(This special issue belongs to the Section Oncology)

Low Back Pain: Clinical Treatment and Management

edited by

Raffaello Pellegrino

and

Angelo Di Iorio

submission deadline 20 Nov 2025 | Viewed by 36 | Submission Open

Keywords: exercise; rehabilitation; weight loss; telerehabilitation; pain; physical therapy; treatment; conservative treatment; intervertebral disk displacement; low back pain; sciatica

(This special issue belongs to the Section Clinical Neurology)

Clinical Procedures for Diagnosis and Treatment of Cardiovascular Diseases

edited by Ahmad Jabri, Mohammad Alqarqaz, Qais Radaideh and Ahmad Al-Abdouh

submission deadline 20 Nov 2025 | Viewed by 29 | Submission Open

Keywords: cardiovascular disease; diagnostic imaging; minimally invasive procedures; precision medicine; artificial intelligence; interventional cardiology; surgical innovations; patient outcomes; preventive cardiology

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Insights in Maternal–Fetal Medicine

edited by Moti Gulersen

submission deadline 20 Nov 2025 | Viewed by 25 | Submission Open

Keywords: preterm birth; antenatal corticosteroids; preeclampsia; ultrasound; fetal growth; congenital anomalies; infection; maternal morbidity; diabetes; multiple gestation

(This special issue belongs to the Section Obstetrics & Gynecology)

Diagnosis and Treatment of Scoliosis and Spinal Deformity

edited by Anna Rienmueller and Kenny Yat Hong Kwan

submission deadline 20 Nov 2025 | Viewed by 17 | Submission Open

Keywords: scoliosis; spinal deformity; adolescent idiopathic scoliosis (AIS); early onset scoliosis (EOS); neuromuscular scoliosis; adult spinal deformity (ASD); operative treatment; spinal fusion; neuromonitoring in scoliosis and deformity surgery; perioperative risk factors; conservative treatment; bracing therapy; physiotherapy scoliosis-specific exercises (PSSE) and Schroth therapy; spinal biomechanics; scoliosis imaging; low-dose radiation imaging; artificial intelligence in scoliosis; 3D modelling in spinal deformity including surgical planning; predictive modelling in scoliosis progression; biomechanics of spinal curvature; growth modulation; patient-reported outcomes in scoliosis treatment

(This special issue belongs to the Section Orthopedics)

Research Advances in Coagulation Disorders

edited by Alberto Maino

submission deadline 21 Nov 2025 | Viewed by 53 | Submission Open

Keywords: coagulation; bleeding disorders; thrombosis; hemophilia; clotting disorders; hematology

(This special issue belongs to the Section Hematology)

Effect of Long-Term Insomnia on Mental Health—2nd Edition

edited by

Aleksandra Rogowska

submission deadline 21 Nov 2025 | Viewed by 48 | Submission Open

Keywords: anxiety; alcohol and substance use disorders; behavioral addiction; burnout; cognitive dysfunction; depression; eating disorders; gaming addiction; problematic internet/social media use; insomnia; long-term insomnia; mood disorders; post-traumatic stress disorder; stress

(This special issue belongs to the Section Mental Health)

Clinical Diagnosis and Management of Vestibular Disorders

edited by Sinisa Maslovara, Mario Habek and

Andro Košec

submission deadline 25 Nov 2025 | 3 articles | Viewed by 2476 | Submission Open

Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management

(This special issue belongs to the Section Otolaryngology)

Clinical Pharmacology: Adverse Drug Reactions

edited by

Andrej Belančić

and Ivana Mudnić

submission deadline 25 Nov 2025 | 1 articles | Viewed by 293 | Submission Open

Keywords: pharmacology; adverse drug reactions; drug interactions; pharmacovigilance; drug safety

(This special issue belongs to the Section Pharmacology)

Interstitial Lung Disease Secondary to Autoimmune Disorders: Recent Advances and Novel Perspectives

edited by

Gaetano La Rocca

Gianluca Sambataro

and Francesco Ferro

submission deadline 25 Nov 2025 | Viewed by 100 | Submission Open

Keywords: interstitial lung disease; lung involvement; connective tissue diseases; rheumatoid arthritis; systemic vasculitis; radiomics; lung ultrasound; biomarkers; pathogenetic immunological pathways; therapeutic targets

(This special issue belongs to the Section Respiratory Medicine)

New Horizons in Aortic Valve Replacement

edited by Abdellaziz Dahou

submission deadline 25 Nov 2025 | Viewed by 78 | Submission Open

Keywords: aortic valve; aortic stenosis; TAVR; SAVR; valve durability; aortic valve replacement; transcatheter aortic valve replacement; surgical aortic valve replacement

(This special issue belongs to the Section Cardiology)

Interstitial Lung Diseases: New Treatments Based on Treatable Traits

edited by Francesco Amati

submission deadline 25 Nov 2025 | Viewed by 77 | Submission Open

Keywords: interstitial lung diseases; progressive pulmonary fibrosis; phenotypes; endotypes; treatment; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Anemia: Clinical Updates in Diagnosis, Management, and Treatment

edited by

Joan-Lluis Vives-Corrons

submission deadline 25 Nov 2025 | Viewed by 62 | Submission Open

Keywords: anemia; diagnostic tools; hematology; artificial intelligence; targeted therapy; hereditary hemolytic anemia

(This special issue belongs to the Section Hematology)

Recent Advances in Diagnosis and Treatment of Comorbid Disorders in Interstitial Lung Diseases

edited by

Giacomo Sica

and Domenica Francesca Mariniello

submission deadline 25 Nov 2025 | Viewed by 61 | Submission Open

Keywords: interstitial lung disease; ILD; progressive pulmonary fibrosis; artificial intelligence; management

(This special issue belongs to the Section Respiratory Medicine)

New Insights in Paediatric Endocrinology

edited by

Marco Fiore

submission deadline 25 Nov 2025 | Viewed by 53 | Submission Open

Keywords: endocrinology; pediatrics; hormones; therapy and treatment; adolescents; newborns

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Highlights in Uveal Melanoma

edited by Tomasz Chorągiewicz and

Joanna Dolar-Szczasny

submission deadline 25 Nov 2025 | Viewed by 50 | Submission Open

Keywords: choroidal melanoma; uveal melanoma; radiotherapy; enucleation; brachytherapy

(This special issue belongs to the Section Ophthalmology)

The Use of Circulating Extracellular Vesicles as a Tool in the Diagnosis, Monitoring and Treatment of Disease

edited by

Antonio Casado-Díaz

submission deadline 25 Nov 2025 | Viewed by 48 | Submission Open

Keywords: circulating extracellular vesicles; regenerative medicine; biomarker; diagnosis; exosomes; liquid biopsy

(This special issue belongs to the Section Clinical Laboratory Medicine)

Clinical Updates in Reproductive Endocrinology: 2nd Edition

edited by Iwona Bojar and

Dorota Raczkiewicz

submission deadline 25 Nov 2025 | Viewed by 48 | Submission Open

Keywords: reproductive endocrinology; endocrine diseases in pregnancy; infertility; endocrine diagnostics in infertility; long-term consequences of endocrine disorders; therapy for endocrine disorders

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Clinical Advances in Urinary Incontinence

edited by Adolf Lukanovic, David Lukanović and Mija Blaganje

submission deadline 25 Nov 2025 | Viewed by 46 | Submission Open

Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices

(This special issue belongs to the Section Nephrology & Urology)

Enhancing Safety and Outcomes in Complex Spine Surgery

edited by Ahmed Ramadan Sadek

submission deadline 25 Nov 2025 | Viewed by 46 | Submission Open

Keywords: spinal surgery; spinal deformity; scoliosis; sciatica; back and neck pain

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Surgical Treatment for Hepato–Pancreatic–Biliary (HPB) Diseases

edited by

Spiros G. Delis

submission deadline 25 Nov 2025 | Viewed by 45 | Submission Open

Keywords: pancreas surgery; liver resection; minimal invasive approach; virtual reality; robotic surgery; MDT

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Adverse Pregnancy and Neonatal Outcomes

edited by

Sae-kyung Choi

submission deadline 25 Nov 2025 | Viewed by 43 | Submission Open

Keywords: maternal and fetal; adverse pregnancy; neonatal outcomes; newborns; cesarean section

(This special issue belongs to the Section Obstetrics & Gynecology)

Minimally Invasive Laparoendoscopic Procedures in Abdominal Emergencies

edited by

Eugen Tãrcoveanu

Costel Bradea

and

Alin Mihai Vasilescu

submission deadline 25 Nov 2025 | Viewed by 41 | Submission Open

Keywords: laparoscopic surgery; robotic surgery; minimally invasive surgery; hepatobiliary surgery; pancreatic surgery; gastrointestinal surgery; general surgery; emergency surgery; trauma; recent advances in laparoscopic surgery; surgical training in laparoscopy; endoscopic surgery; the feasibility and safety of laparoscopic; endoscopic co-operative surgery for the treatment of digestive pathology

(This special issue belongs to the Section General Surgery)

Ventricular Assist Devices: Clinical Advances in Practice and Future Perspectives

edited by Balakrishnan M. Mahesh

submission deadline 25 Nov 2025 | Viewed by 40 | Submission Open

Keywords: ventricular assist device; mechanical circulatory support; pulsatile pneumatic devices; microaxial intraventricular de-vices; magnetically levitated devices; cardiac transplantation; donor circulatory death; normothermic regional perfusion

(This special issue belongs to the Section Cardiology)

Clinical Advances in Spinal Neurosurgery

edited by Jang-Won Yoon

submission deadline 25 Nov 2025 | Viewed by 39 | Submission Open

Keywords: minimally invasive spine surgery; lateral lumbar interbody fusion; endoscopic spine surgery; patient-reported out-comes; functional assessment; perioperative care; surgical decision-making

(This special issue belongs to the Section Clinical Neurology)

Advances in Ablation Therapy for Atrial Fibrillation: Innovations and Clinical Applications

edited by Ioanna Koniari

submission deadline 25 Nov 2025 | Viewed by 38 | Submission Open

Keywords: atrial fibrillation; ablation; PFA; PVI; non-thermal energy; mapping system

(This special issue belongs to the Section Cardiology)

Treatment and Digital Outcome Assessment in Orthopaedic Trauma

edited by Benedikt Johannes Braun and

Meir Tibi Marmor

submission deadline 25 Nov 2025 | Viewed by 36 | Submission Open

Keywords: orthopaedic trauma; digital outcome assessment; wearable sensors; patient-reported outcomes; machine learning (or artificial intelligence)

(This special issue belongs to the Section Orthopedics)

Approaches and Challenges in Oral Rehabilitation

edited by

Yoko Hasegawa

and Takayuki Kosaka

submission deadline 25 Nov 2025 | Viewed by 33 | Submission Open

Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Diabetic Foot: Emerging Prevention Strategies and Epidemiology

edited by

Vilma Urbančič-Rovan

submission deadline 25 Nov 2025 | Viewed by 28 | Submission Open

Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry

(This special issue belongs to the Section Endocrinology & Metabolism)

Surgery in the Era of Neoadjuvant Immune Checkpoint Inhibitors Therapy for Thoracic Oncology

edited by

Mohsen Ibrahim

submission deadline 25 Nov 2025 | Viewed by 27 | Submission Open

Keywords: neoadjuvant therapy; immune checkpoint inhibitors; unresectable disease; lung cancer; locally advanced lung cancer

(This special issue belongs to the Section General Surgery)

Ventilation in Critical Care Medicine: 2nd Edition

edited by Gianluca Zani

submission deadline 25 Nov 2025 | Viewed by 27 | Submission Open

Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation

(This special issue belongs to the Section Intensive Care)

New Approaches in Open and Minimally Invasive Surgery for Abdominal Oncologic Surgery

edited by

Alessandro Coppola

and Immacolata Iannone

submission deadline 25 Nov 2025 | Viewed by 25 | Submission Open

Keywords: surgical oncology; early diagnosis; minimally invasive surgery; personalized medicine; combined therapy; gastrointestinal cancer; oligometastatic cancer; peritoneal disease

(This special issue belongs to the Section General Surgery)

Advances in the Clinical Management of Perioperative Anesthesia: 2nd Edition

edited by Alessia Mattei, Rita Cataldo and

Alessandro Strumia

submission deadline 25 Nov 2025 | Viewed by 25 | Submission Open

Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit

(This special issue belongs to the Section Anesthesiology)

Clinical Innovation in Endoscopic Sinus and Anterior Skull Base Surgery

edited by

Samiul Muquit

and

Marios Stavrakas

submission deadline 27 Nov 2025 | Viewed by 34 | Submission Open

Keywords: rhinology; endoscopic anterior skull base surgery; anterior skull base surgery; endoscopic sinus surgery; chronic rhinosinusitis (CRS); otolaryngology

(This special issue belongs to the Section Otolaryngology)

Management of Complex Infective Endocarditis

edited by Shekhar Saha, Tulio Caldonazo and Mateo Marin-Cuartas

submission deadline 27 Nov 2025 | Viewed by 27 | Submission Open

Keywords: infective endocarditis; imaging; diagnosis; cardiac surgery; pathogens; antibiotic treatment; risk estimation

(This special issue belongs to the Section Cardiology)

Displaying special issue 1101-1150 on page 23 of 27.

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