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Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 458

Special Issue Editor


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Guest Editor
Advanced Heart Disease, Replacement and Recovery Program, Baylor Scott and White Health, Temple, TX, USA
Interests: cardiogenic shock; heart replacement; heart recovery; transitions in mechanical circulatory support
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Special Issue Information

Dear colleagues,

It is my pleasure to invite you to contribute to this Special Issue, titled “Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition”. This is a new edition; we published six papers in the first edition. For more details, please visit https://www.mdpi.com/journal/jcm/special_issues/0448MPMR3Z.

Cardiogenic shock remains a complex disease entity, associated with high mortality, that compromises the well-being of patients and caregivers across healthcare systems across the world. Increased recognition of the spectral nature of cardiogenic shock has led to a movement towards early interventions associated with diagnostic profiles that inform and tailor disease-specific interventions. Importantly, severe refractory cardiogenic shock, complicated by cardiac arrest, carries an exceedingly high mortality and, paradoxically, most of the contemporary interventions are oftentimes utilized. In this context, classifications, team-based approaches, and systems of care that allow for the early recognition of the disease have emerged in an attempt to halt hemometabolic involvement and provide transitions, including heart recovery or remission. Important progress has been made with the use of distinct temporary mechanical circulatory support devices tailored to right, left, or biventricular support; however, knowledge gaps remain on the multiple associated clinical interventions required to help patients transition to longitudinal well-being. Aspects related to decongestion, weaning, and the escalation of temporary MCS, as well as strategies that promote ambulation, nutrition, and end-organ recovery (including neuroprotection after cardiac arrest), are some of the ongoing clinical questions that need to be addressed to best understand this rapidly evolving field and guide clinicians. In this Special Issue, we invite authors to submit papers on the clinical advances in the management of cardiogenic shock and cardiac arrest.

Dr. Jaime A. Hernández-Montfort
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiogenic shock
  • cardiac arrest
  • temporary mechanical circulatory support
  • ECMO
  • transitions
  • heart recovery
  • heart replacement

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Published Papers (1 paper)

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9 pages, 1563 KiB  
Case Report
High Profile Transvalvular Pump Assisted Recovery for Takotsubo Cardiomyopathy: A Case Series
by Jordan Young, Patrick McGrade, Jaime Hernandez-Montfort and Jerry Fan
J. Clin. Med. 2025, 14(9), 3225; https://doi.org/10.3390/jcm14093225 - 6 May 2025
Viewed by 256
Abstract
Background: Stress-induced cardiomyopathy (SI-CM) is a transient left ventricular dysfunction triggered by emotional or physical stress, often resolving with supportive care. However, severe cases may progress to cardiogenic shock (CS), requiring mechanical circulatory support (MCS). High-profile transvalvular pumps (HPTP), a form of percutaneous [...] Read more.
Background: Stress-induced cardiomyopathy (SI-CM) is a transient left ventricular dysfunction triggered by emotional or physical stress, often resolving with supportive care. However, severe cases may progress to cardiogenic shock (CS), requiring mechanical circulatory support (MCS). High-profile transvalvular pumps (HPTP), a form of percutaneous ventricular assist device, offer promising hemodynamic support in acute heart failure. This report explores HPTP use in SI-CM-related CS through two complex clinical cases. Case Summary: Two elderly female patients presented with severe CS secondary to apical-variant SI-CM. Case 1 involved a 67-year-old woman with sepsis, colonic perforation, and recurrent SI-CM, leading to profound low-output shock despite multiple vasopressors and inotropes. HPTP was implanted via the axillary artery, allowing for surgical management of intra-abdominal pathology and eventual cardiac recovery. Case 2 featured a 77-year-old woman with multifocal pneumonia, severe mitral regurgitation, and complete heart block. HPTP implantation stabilized her hemodynamics, facilitated extubation, and led to full recovery of ventricular function. Results: Both patients showed marked improvement in cardiac output and systemic perfusion following HPTP insertion. Echocardiograms post-device removal revealed normalization of left ventricular ejection fraction (55–64%). Hemodynamic data confirmed reduced pulmonary capillary wedge pressure and systemic vascular resistance. Conclusion: These cases highlight the potential of HPTP in managing SI-CM-related CS, especially when traditional therapies are inadequate or contraindicated. HPTP can rapidly restore hemodynamic stability and support myocardial recovery. While current data are limited, these observations underscore the need for broader investigation into the role of HPTP in this setting. Full article
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