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Current Status and Future of Urological Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: 20 January 2026 | Viewed by 120

Special Issue Editors


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Guest Editor
Department of Urology, Humanitas Gavazzeni, Bergamo, Italy
Interests: cystectomy; bladder cancer; prostate cancer; ureterocutaneostomy; urologic oncology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Urology, Humanitas Gavazzeni, Bergamo, Italy
Interests: bladder cancer; prostatectomy; robotic-assisted surgery; urological surgery; andrological; urinary incontinence

E-Mail Website
Guest Editor
Department of Urology, Humanitas Gavazzeni, Bergamo, Italy
Interests: cystectomy; bladder cancer; prostate cancer; ureterocutaneostomy; urologic oncology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Urological surgery is undergoing a dynamic and profound transformation, fueled by continuous technological innovation and the growing need for treatments that are personalized, effective, and minimally invasive. Robotic-assisted surgery—once the domain of high-volume reference centers—is now entering a new phase of accessibility thanks to the advent of new robotic platforms and market competition. This evolution is fostering broader adoption, technical refinement, and improved patient outcomes.

At the same time, digital tools such as artificial intelligence, augmented reality, and advanced surgical navigation systems are increasingly integrated into the operating room, revolutionizing surgical planning, intraoperative decision-making, and education. Minimally invasive techniques, including endoscopic and laparoscopic procedures, are being optimized and adapted to tackle more complex cases. Furthermore, reconstructive and functional urology are equally benefitting from enhanced anatomical knowledge and the development of innovative biomaterials.

These advances are shaping the management of a wide spectrum of urological conditions—from oncological diseases such as prostate and bladder cancer to benign disorders like BPH and urinary incontinence—with the shared goal of improving functional and oncologic outcomes while reducing morbidity and recovery time.

This Special Issue invites high-quality original research articles and in-depth reviews from clinicians and researchers engaged in cutting-edge urological surgery. Submissions should aim to critically assess current standards, explore promising technologies, and provide solid scientific evidence to guide the next era of surgical practice.

We look forward to your valuable contributions to help define the future of urological surgery.

Dr. Filippo Marino
Dr. Davide De Marchi
Dr. Luca Di Gianfrancesco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • urological surgery
  • robotic-assisted surgery
  • minimally invasive surgery
  • artificial intelligence
  • augmented reality
  • surgical navigation
  • endourology
  • laparoscopic urology
  • reconstructive urology
  • functional urology
  • bph treatment
  • urinary incontinence
  • prostate cancer surgery
  • bladder cancer surgery
  • surgical innovation
  • digital surgery

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Published Papers (1 paper)

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Research

15 pages, 451 KB  
Article
Impact of On-Demand Selective Suturing on Renal Function Preservation During Clampless Robotic-Assisted Partial Nephrectomy: Insights from a Large Multicentric Italian Cohort
by Angelo Porreca, Davide De Marchi, Filippo Marino, Marco Giampaoli, Daniele D’Agostino, Francesca Simonetti, Antonio Amodeo, Paolo Corsi, Francesco Claps, Alessandro Crestani, Daniele Romagnoli, Pier Paolo Prontera, Gian Maria Busetto and Luca Di Gianfrancesco
J. Clin. Med. 2025, 14(21), 7534; https://doi.org/10.3390/jcm14217534 (registering DOI) - 24 Oct 2025
Abstract
Objectives: To evaluate perioperative outcomes, renal function preservation, and short-term oncologic results of off-clamp, sutureless, or selectively sutured robotic-assisted partial nephrectomy (RAPN) in patients with renal tumors treated at multiple high-volume centers. Methods: This multicenter retrospective study included 250 patients who [...] Read more.
Objectives: To evaluate perioperative outcomes, renal function preservation, and short-term oncologic results of off-clamp, sutureless, or selectively sutured robotic-assisted partial nephrectomy (RAPN) in patients with renal tumors treated at multiple high-volume centers. Methods: This multicenter retrospective study included 250 patients who underwent off-clamp, sutureless/selectively sutured RAPN between January 2018 and December 2024. Patients with solitary kidneys, tumors > 7 cm, or prior renal surgery were excluded. All procedures were performed without renal artery clamping, using hemostatic agents and selective suturing when necessary. Perioperative, functional, and oncologic outcomes were compared with 313 patients who underwent standard RAPN with parenchymal suturing. Results: The median operative time was 110 min (IQR 100–140), and the median estimated blood loss was 180 mL (IQR 100–250). The overall complication rate was 8.4%, predominantly Clavien–Dindo grade I–II, with no conversions to open surgery. The median decline in estimated glomerular filtration rate (eGFR) at three months was 5.5% (IQR 3.5–8.9; p = 0.56), and no cases of acute kidney injury were recorded. The positive surgical margin rate was 3.7%, and no tumor recurrences were observed during the 12-month follow-up period. Conclusions: Off-clamp, sutureless or selectively sutured robotic-assisted partial nephrectomy (RAPN) was not associated with increased perioperative risk, renal functional decline, or compromised short-term oncologic control compared with conventional sutured RAPN. These findings indicate that the technique is feasible and safe in appropriately selected patients, although prospective studies with longer follow-up are needed to confirm long-term outcomes and refine patient selection criteria. Full article
(This article belongs to the Special Issue Current Status and Future of Urological Surgery)
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