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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pediatric Dentistry: Real-World Clinical Insights

edited by

Ruth M. Santamaría

submission deadline 20 Oct 2026 | 3 articles | Viewed by 3003 | Submission Open

Keywords: pediatric dentistry; minimally invasive dentistry; new technologies; biomaterials; innovative management approaches; caries management; pulp management; dental trauma; molar incisor hypomineralization; public health services research; epidemiological research; translational research

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Updates in Imaging of Musculoskeletal Diseases

edited by

Federico Zaottini

and

Riccardo Picasso

submission deadline 20 Oct 2026 | 4 articles | Viewed by 2853 | Submission Open

Keywords: musculoskeletal imaging; ultrasound; magnetic resonance; sport imaging; rheumatology; nerve imaging

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Advances and Clinical Outcomes of Endocrinology

edited by Stefana Catalina Bilha and

Cristina Preda

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2825 | Submission Open

Keywords: endocrinology; obesity; metabolic and bone disease; chronic conditions

(This special issue belongs to the Section Endocrinology & Metabolism)

Hip and Knee Arthroplasty: Update on Clinical Management

edited by Maximilian F. Kasparek

submission deadline 20 Oct 2026 | 4 articles | Viewed by 2531 | Submission Open

Keywords: total hip arthroplasty (THA); total knee arthroplasty (TKA); revision arthroplasty; implant fixation; cemented; cementless; hybrid; alignment in TKA; mechanical alignment; kinematic alignment; restricted kinematic alignment; functional alignment; navigation; robotic-assisted surgery; patient-specific instrumentation; additive manufacturing; 3D printing; personalized implant

(This special issue belongs to the Section Orthopedics)

Orofacial Pain: Innovations in Treatment Modalities and Patient Care

edited by

Takahiko Nagamine

submission deadline 20 Oct 2026 | 1 articles | Viewed by 2425 | Submission Open

Keywords: orofacial pain; treatment; patient care; oral dysfunction; chronic pain; burning mouth syndrome; temporomandibular joint pain: oral cenesthopathy; atypical odontalgia; phantom bite syndrome

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Periodontology and Dental Implants: State of the Art and Future Perspectives

edited by Magda Mensi and

Davide Farronato

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2348 | Submission Open

Keywords: periodontology; dental implants; regenerative dentistry; peri-implant diseases; digital dentistry; implant surface modifications; tissue engineering; oral microbiome; risk assessment; personalized treatment

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Challenges and Perspectives in Surgical Treatment of Spinal Deformity

edited by Jung-Hee Lee

submission deadline 20 Oct 2026 | 4 articles | Viewed by 2271 | Submission Open

Keywords: adult spinal deformity; decompensation; kyphosis; lateral lumbar interbody fusion; orthopedic surgery; osteotomy; proximal junctional kyphosis; rod fracture

(This special issue belongs to the Section Orthopedics)

Optimizing Outcomes in Emergency Medicine and Cardiopulmonary Resuscitation

edited by

Andreas S. Papazoglou

and

Dimitrios V. Moysidis

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2080 | Submission Open

Keywords: emergency medicine; cardiopulmonary resuscitation; prehospital care; outcome prediction; post-pesuscitation care; advanced life support; emergency response systems; medical ethics; simulation in medicine

(This special issue belongs to the Section Emergency Medicine)

Clinical Advances in Endodontic Dentistry

edited by

Luciano Giardino

and

Luigi Generali

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2035 | Submission Open

Keywords: antimicrobial agents; biofilm; confocal laser scanning microscopy; endodontic materials; irrigants; microbiome; micro-CT; regenerative endodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Peritoneal Dialysis and Hemodialysis: Early and Late Outcomes

edited by

Keren Cohen-Hagai

and

David Pereg

submission deadline 20 Oct 2026 | 3 articles | Viewed by 1951 | Submission Open

Keywords: peritoneal dialysis; dialysis; hemodialysis; chronic kidney disease; end-stage renal disease

(This special issue belongs to the Section Nephrology & Urology)

Retinal Diseases: Emerging Therapies and Vision Rehabilitation

edited by

Hisanori Imai

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1929 | Submission Open

Keywords: vitreoretinal disorder; vitrectomy; digital assisted vitrectomy; intraoperative optical coherence tomography; diabetic retinopathy; epiretinal membrane

(This special issue belongs to the Section Ophthalmology)

Advances in Clinical Craniofacial Reconstructive Surgery

edited by Rami S. Kantar

submission deadline 20 Oct 2026 | 2 articles | Viewed by 1621 | Submission Open

Keywords: craniofacial; craniofacial conditions; craniofacial surgery; cleft; cleft lip; cleft palate; reconstructive surgery; craniofacial anomalies

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Prostate Surgery: The Latest Advances and Future Trends

edited by Akhil K. Das and

Bruce Gao

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1558 | Submission Open

Keywords: benign prostatic hyperplasia (BPH); minimally invasive surgical therapies (MIST); laser enucleation (HoLEP; ThuLEP); Aquablation; Rezum; robotic prostatectomy; anatomic enucleation

(This special issue belongs to the Section Nephrology & Urology)

New Insights in Joint Arthroplasty—2nd Edition

edited by

Richard Lass

submission deadline 20 Oct 2026 | 4 articles | Viewed by 1558 | Submission Open

Keywords: total hip arthroplasty; total knee arthroplasty; robotic-assisted technology and navigation; modern implant materials; modern implant fixation techniques; alignment in TKA; spinopelvic alignment in THA

(This special issue belongs to the Section Orthopedics)

New Sights in Retinal Diseases Therapeutics: Innovation and Clinical Practice

edited by

Giacomo Boscia

Pasquale Viggiano

, Stefano Dore and Alfonso Savastano

submission deadline 20 Oct 2026 | 3 articles | Viewed by 1494 | Submission Open

Keywords: retinal diseases; central serous chorioretinopathy; age-related macular degeneration; eye diseases; diabetic retinopathy

(This special issue belongs to the Section Ophthalmology)

Surgical Insights into Foot and Ankle Diseases

edited by Konstantinos Tsikopoulos

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1493 | Submission Open

Keywords: lower limb surgery; infection research; foot and ankle

(This special issue belongs to the Section Orthopedics)

Paradigm Changes in Cardiac Surgery and Interventional Cardiology

edited by

Miklos Bitay

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1352 | Submission Open

Keywords: cardiac surgery; trans-catheter interventions; ischaemic heart disease; structural heart disease; electrophysiological interventions; state-of-the-art techniques; golden standards; therapeutic guidelines

(This special issue belongs to the Section Cardiology)

Patient-Reported Outcomes (PROs) in Inflammatory Bowel Disease (IBD) Around the World—2nd Edition

edited by Irina Blumenstein

submission deadline 20 Oct 2026 | 2 articles | Viewed by 1334 | Submission Open

Keywords: inflammatory bowel disease; patient-reported outcomes; symptom burden; quality of life; treatment satisfaction

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Innovations in Surgical and Medical Approaches of Urologic Oncology

edited by

Sung Han Kim

submission deadline 20 Oct 2026 | 2 articles | Viewed by 1189 | Submission Open

Keywords: urologic oncology; robotic surgery; immunotherapy; targeted therapy; image-guided techniques; personalized medicine; minimally invasive surgery; focal therapy

(This special issue belongs to the Section Nephrology & Urology)

Recent Developments in Gynecological Endocrinology: 2nd Edition

edited by

Błażej Męczekalski

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1049 | Submission Open

Keywords: amenorrhea; puberty; PCOS; premature ovarian insufficiency; endometriosis; infertility; pregnancy; hormones; menopause

(This special issue belongs to the Section Obstetrics & Gynecology)

Genitourinary Tumors and Radiation Therapy: Current Advances and Future Directions

edited by Shalini Moningi

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1040 | Submission Open

Keywords: cancer; prostate cancer; bladder cancer; kidney cancer; radiation therapy

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Novel Advances in Lower Limb Trauma and Orthopaedic Surgery

edited by Konstantinos Tsikopoulos and

Panagiotis Givissis

submission deadline 20 Oct 2026 | 1 articles | Viewed by 951 | Submission Open

Keywords: lower limb orthopedic surgery; trauma; infection; research

(This special issue belongs to the Section Orthopedics)

New Perspectives on Interventional Treatment of Coronary Artery Disease

edited by Mohammad Reza Movahed

submission deadline 20 Oct 2026 | 1 articles | Viewed by 898 | Submission Open

Keywords: complex coronary intervention; coronary bifurcation; new frontiers in interventional cardiology; calcified lesions; chronic total occlusions; high-pressure balloons; intracoronary lithotripsy

(This special issue belongs to the Section Cardiology)

Geriatric Fracture Care: Bridging Orthopedics and Gerontology

edited by Tom Knauf and Daphne Asimenia Eschbach

submission deadline 20 Oct 2026 | 1 articles | Viewed by 855 | Submission Open

Keywords: geriatric fracture; proximal femur fractures; hip fracture; geriatric trauma patient; ortho-geriatric treatment; periprosthetic fracture; end of life decision; orthopedic surgery in the elderly

(This special issue belongs to the Section Geriatric Medicine)

Advances in the Management and Understanding of Adult Respiratory Diseases

edited by Hirotsugu Ohkubo

submission deadline 20 Oct 2026 | 1 articles | Viewed by 778 | Submission Open

Keywords: chronic lung disease; interstitial lung disease; chronic obstructive pulmonary disease; bronchiectasis; nutrition and sarcopenia; pulmonary rehabilitation; imaging and prognosis

(This special issue belongs to the Section Respiratory Medicine)

Bruxism and Temporomandibular Disorders: Assessment and Clinical Insights

edited by

Aneta Wieczorek

Małgorzata Kulesa-Mrowiecka

and

Michał Ginszt

submission deadline 20 Oct 2026 | 2 articles | Viewed by 740 | Submission Open

Keywords: bruxism; temporomandibular disorders; TMD; clinical assessment; diagnosis; orofacial pain; masticatory system; interdisciplinary management

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Multimorbidity and Polypharmacy: From Clinical Complexity to Patient Safety

edited by

Cristina Ghiciuc

and

Mihaela Simona Naidin

submission deadline 20 Oct 2026 | 1 articles | Viewed by 739 | Submission Open

Keywords: multimorbidity; polypharmacy; patient safety; medication management; diabetes

(This special issue belongs to the Section Pharmacology)

New Advances in Prenatal Diagnosis and Newborn Medicine, 2nd Edition

edited by

Zoltan Kozinszky

and

Andrea Suranyi

submission deadline 20 Oct 2026 | 1 articles | Viewed by 726 | Submission Open

Keywords: sonographic parameters; molecular markers; extravillous and villous trophoblast; perinatal ultrasound; serum markers for complications of pregnancy; histopathology of the placenta; neonatal pathological conditions

(This special issue belongs to the Section Obstetrics & Gynecology)

Pediatric Cardiology: Clinical Insights, Diagnostic Advances, and Therapeutic Challenges

edited by

Corina Maria Vasile

submission deadline 20 Oct 2026 | 1 articles | Viewed by 682 | Submission Open

Keywords: pediatric cardiology; congenital heart disease; cardiac imaging; pediatric arrhythmias; interventional cardiology; cardiomyopathy; heart failure in children; precision medicine; long-term outcomes; transition of care

(This special issue belongs to the Section Clinical Pediatrics)

Advances in Cervical Spine Surgery: Techniques, Outcomes, and Complications

edited by

Bartosz Godlewski

and Tae Sik Goh

submission deadline 20 Oct 2026 | 2 articles | Viewed by 681 | Submission Open

Keywords: cervical spine; fusion assessment; surgical outcomes; cervical alignment; radiological measurements; subsidence; surgical complications

(This special issue belongs to the Section Orthopedics)

Acute Kidney Injury: Current Challenges and Future Directions in Diagnosis and Treatment

edited by

Grazia Maria Virzì

submission deadline 20 Oct 2026 | 1 articles | Viewed by 669 | Submission Open

Keywords: acute kidney injury (AKI); biomarkers; precision nephrology; AKI-to-CKD transition; renal replacement therapy (RRT); subclinical AKI; sepsis-associated AKI; renal recovery

(This special issue belongs to the Section Nephrology & Urology)

Advances in the Clinical Management of Myocardial Infarction

edited by Raef A. Fadel and Ahmad R. Jabri

submission deadline 20 Oct 2026 | 1 articles | Viewed by 633 | Submission Open

Keywords: myocardial infarction; percutaneous coronary intervention; troponin; antiplatelet therapy; cardiogenic shock; heart failure; ischemic cardiomyopathy; mechanical circulatory support

(This special issue belongs to the Section Cardiology)

Spine Surgery: Current Challenges and Future Perspectives

edited by Omri Maayan

submission deadline 20 Oct 2026 | 1 articles | Viewed by 622 | Submission Open

Keywords: orthopedic surgery; spine surgery; minimally invasive spine surgery; adult spinal deformity; patient-reported outcomes; navigation and robotics; artificial intelligence; surgical outcomes; value-based care; enhanced recovery after surgery; quality improvement; motion-preservation; machine learning; predictive analytics

(This special issue belongs to the Section Orthopedics)

Coronary Artery Disease: Recent Developments and Emerging Trends

edited by

Attila Kardos

and Tarun Mittal

submission deadline 20 Oct 2026 | 1 articles | Viewed by 605 | Submission Open

Keywords: coronary atherosclerosis; diagnostic strategies; therapeutic options; timing of intervention; artificial intelligence; novel therapeutic pathways

(This special issue belongs to the Section Cardiology)

Advancing Ultrasound Techniques with Artificial Intelligence in Clinical Research

edited by

Yale Tung-Chen

submission deadline 20 Oct 2026 | 1 articles | Viewed by 600 | Submission Open

Keywords: artificial intelligence; point-of-care ultrasound; machine learning; deep learning; medical imaging; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)

Recent Advances and Future Trends in Shoulder Surgery

edited by Giovanni Merolla

submission deadline 20 Oct 2026 | 1 articles | Viewed by 546 | Submission Open

Keywords: rotator cuff; shoulder instability; acromion-clavicular joint; arthroplasty; shoulder rehabilitation

(This special issue belongs to the Section Orthopedics)

Advances in Plastic and Reconstructive Surgery: Bridging Function, Aesthetics, and Innovation

edited by

Francesco Ruben Giardino

, Giuseppe Angelo Giovanni Lombardo and

Roberto Cuomo

submission deadline 20 Oct 2026 | 1 articles | Viewed by 534 | Submission Open

Keywords: body-contour; reconstruction; aesthetic; regenerative surgery; plastic surgery; breast reconstruction; microsurgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Sepsis and Organ Dysfunction: New Insights into Diagnosis and Treatment—Second Edition

edited by

Barbara Adamik

submission deadline 20 Oct 2026 | 1 articles | Viewed by 532 | Submission Open

Keywords: intensive care; sepsis; shock; biomarkers; rapid methods for pathogen identification; multiorgan dysfunction syndrome; extracorporeal methods; mortality

(This special issue belongs to the Section Intensive Care)

Current Updates on Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis

edited by

Nikolaos Tsetsos

, Georgios Fyrmpas and

Konstantinos Garefis

submission deadline 20 Oct 2026 | Viewed by 493 | Submission Open

Keywords: endoscopic sinus surgery; rhinology; chronic rhinosinusitis management; functional endoscopic sinus surgery (FESS); sinonasal inflammation; transnasal approach; postoperative outcomes

(This special issue belongs to the Section Otolaryngology)

Clinical Updates and Perspectives on Transcranial Magnetic Stimulation (TMS)—2nd Edition

edited by

Mariagiovanna Cantone

submission deadline 20 Oct 2026 | Viewed by 473 | Submission Open

Keywords: non-invasive brain stimulation; transcranial magnetic stimulation; motor cortex; neuroplasticity; motor learning; dementia; stroke; movement disorders; depression; spinal cord; neuropsychiatric disorders

(This special issue belongs to the Section Clinical Neurology)

Hepatobiliary and Pancreatic Diseases: New Perspectives and Innovative Techniques

edited by

Florin Graur

submission deadline 20 Oct 2026 | 1 articles | Viewed by 472 | Submission Open

Keywords: hepatobiliary diseases; pancreatic diseases; AI in hepatobiliary and pancreatic diseases; minimally invasive and robotic surgery; clinical medicine

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Concepts in Outcomes and Outcome Assessment in Oculoplastic Care

edited by Yinon Shapira

submission deadline 20 Oct 2026 | 2 articles | Viewed by 456 | Submission Open

Keywords: oculoplastic care; clinical outcomes; outcome assessment; eyelid and orbital disorders; lacrimal disease; anophthalmic rehabilitation; aesthetic and reconstructive ophthalmic plastic surgery

(This special issue belongs to the Section Ophthalmology)

Clinical Research in Neuro-Ophthalmology

edited by

Eun Hee Hong

and Hyuna Kim

submission deadline 20 Oct 2026 | 1 articles | Viewed by 406 | Submission Open

Keywords: neuro-ophthalmology; optic neuropathy; visual pathway; biomarker; clinical research; epidemiologic study; AI

(This special issue belongs to the Section Ophthalmology)

Technological Innovations in Spine Surgery: Diagnosis and Management

edited by

Abdul Karim Ghaith

submission deadline 20 Oct 2026 | 1 articles | Viewed by 406 | Submission Open

Keywords: spine surgery; neurosurgery; spinal imaging; surgical navigation; robotic spine surgery; artificial intelligence; ma-chine learning; minimally invasive spine surgery; spinal trauma; spinal tumors; surgical innovation; intraoperative technology; outcome prediction; precision surgery; digital health

(This special issue belongs to the Section Orthopedics)

Latest Advances in Assisted Reproductive Technologies (ART)/In Vitro Fertilization (IVF)

edited by Ravit Nahum

submission deadline 20 Oct 2026 | Viewed by 385 | Submission Open

Keywords: IVF; POR; embryo selection; endometrium; technology

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Updates in Interventional Cardiology

edited by Dobrin Iotkov Vassilev

submission deadline 20 Oct 2026 | 1 articles | Viewed by 384 | Submission Open

Keywords: interventional cardiology; innovation; intravascular imaging; complex PCI; structural heart interventions; personalized treatment strategy

(This special issue belongs to the Section Cardiology)

Innovations in Minimally Invasive Spine Surgery (MISS): Diagnosis and Management

edited by Seong Son

submission deadline 20 Oct 2026 | Viewed by 294 | Submission Open

Keywords: spinal disease; innovative diagnosis; advanced technique; minimally invasive spine surgery; surgical technology; full-endoscopic spine surgery; uniportal endosopy; unilateral biportal endoscopy; biportal endoscopic surgery

(This special issue belongs to the Section Orthopedics)

The Latest Research on Male Infertility

edited by Gianmaria Salvio and Nicola delli Muti

submission deadline 20 Oct 2026 | Viewed by 284 | Submission Open

Keywords: idiopathic male infertility; unexplained male infertility; semen quality; testicular dysfunction; male hypogonadism; gonadal failure

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Up-to-Date Orthopedic Treatment and Care for Osteoporotic Fracture of the Elderly

edited by

Oded Hershkovich

and

Raphael Lotan

submission deadline 20 Oct 2026 | Viewed by 280 | Submission Open

Keywords: osteoporotic fractures; elderly patients; orthopedic surgery; minimally invasive techniques; fracture rehabilitation; kyphoplasty

(This special issue belongs to the Section Orthopedics)

Advances in the Management of Pediatric Neuromuscular Diseases

edited by Nicolas Deconinck

submission deadline 20 Oct 2026 | Viewed by 262 | Submission Open

Keywords: pediatric neuromuscular diseases; neuromuscular disorders (NMD); pediatric; genetic NMD; juvenile myasthenia gravis; chronic demyelinating polyneuropathy; next generation sequencing (NGS); spinal muscular atrophy; Duchenne muscular dystrophy; clinical guidelines

(This special issue belongs to the Section Clinical Neurology)

Displaying special issue 951-1000 on page 20 of 32.

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