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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances and Insights in Cardiovascular Imaging
edited by Maurizio Cusmà Piccione
submission deadline 10 Oct 2026 | Viewed by 160 | Submission Open
Keywords: cardiovascular imaging; multimodality imaging; cardiac magnetic resonance; cardiac computed tomography; advanced echocardiography
(This special issue belongs to the Section Cardiovascular Medicine)
Biomarkers in Peripheral Artery Disease
edited by Ben Li
submission deadline 10 Oct 2026 | Viewed by 147 | Submission Open
Keywords: vascular diseases; biomarkers; diagnosis; prognosis; risk stratification; vascular inflammation; endothelial dysfunc-tion; aneurysmal degeneration; imaging biomarkers; precision medicine
(This special issue belongs to the Section Vascular Medicine)
Treatment Strategies in Congenital Heart Disease: Current Practices and Future Directions
edited by Anastasia Schleiger, Julia Moosmann and
submission deadline 10 Oct 2026 | Viewed by 132 | Submission Open
Keywords: congenital heart disease; transcatheter management of congenital heart defects; surgical strategies for congenital heart defects; medical heart failure treatment; mechanical circulatory support; hybrid procedures; pulmonary hypertension; heart teams; multidisciplinary management; quality of life
(This special issue belongs to the Section Cardiology)
Application of Artificial Intelligence in Cardiology submission deadline 13 Oct 2026 | 8 articles | Viewed by 11455 | Submission Open
Keywords: artificial intelligence; cardiology; clinical practice; valvular heart disease; arrhythmias; device therapy; machine learning
(This special issue belongs to the Section Cardiology)
Clinical Diagnostics and Therapeutic Advances in Pregnancy Complications submission deadline 15 Oct 2026 | 4 articles | Viewed by 6012 | Submission Open
Keywords: prenatal diagnosis; pre-eclampsia; gestational diabetes; pregnancy complications; preterm labor; congenital mal-formations; prenatal genetic testing
(This special issue belongs to the Section Obstetrics & Gynecology)
Innovations in Parkinson’s Disease
edited by
submission deadline 15 Oct 2026 | 4 articles | Viewed by 4737 | Submission Open
Keywords: Parkinson’ s disease; parkinsonism; patient-reported outcomes; wearable technology; disease-modifying therapies; non-pharmacological therapies; care delivery; models of care
(This special issue belongs to the Section Clinical Neurology)
Pharmacotherapy and Patient Care in Rheumatoid Arthritis
edited by
submission deadline 15 Oct 2026 | 2 articles | Viewed by 4048 | Submission Open
Keywords: rheumatoid arthritis; pharmacotherapy; patient care; biomarkers; treatment outcomes
(This special issue belongs to the Section Immunology & Rheumatology)
Retinal Dystrophies—Structure and Function Relationship submission deadline 15 Oct 2026 | 2 articles | Viewed by 2951 | Submission Open
Keywords: retinal dystrophies; structural changes; functional impairment; in retinal degenerative diseases; retinitis pigmentosa
(This special issue belongs to the Section Ophthalmology)
Orthopedic Surgery: Latest Advances and Future Prospects—2nd Edition
edited by Andrea Marinozzi and
submission deadline 15 Oct 2026 | 3 articles | Viewed by 2169 | Submission Open
Keywords: custom-made; regenerative; prosthetic; noninvasive surgery; robotic surgery; percutaneous surgery; minimally invasive surgery
(This special issue belongs to the Section Orthopedics)
Prenatal Diagnosis and Intervention: Shaping the Future of Maternal–Fetal Medicine submission deadline 15 Oct 2026 | 2 articles | Viewed by 1227 | Submission Open
Keywords: diabetes in pregnancy; hypertension in pregnancy; cholestasis in pregnancy; endocrine disorder in pregnancy; sepsis in pregnancy
(This special issue belongs to the Section Obstetrics & Gynecology)
Contemporary Challenges and Advances in Pulmonary Embolism
edited by Roy Beigel, Shlomi Matetzky and Fernando Chernomordik
submission deadline 15 Oct 2026 | 1 articles | Viewed by 698 | Submission Open
Keywords: pulmonary embolism; treatment; coagulation; venous thrombosis; thrombolysis; anticoagulation; risk stratification; PERT; CTEPH
(This special issue belongs to the Section Respiratory Medicine)
Comprehensive Approaches in Gastrointestinal Oncology: Focus on Colorectal, Gastric, and Pancreatic Cancer Treatment submission deadline 15 Oct 2026 | Viewed by 363 | Submission Open
Keywords: colorectal cancer; gastric cancer; pancreatic cancer; biological staging; clinical staging; early tumors; locally advanced tumors; oligometastatic tumor; neoadjuvant approach; chemotherapy; radiotherapy; immunotherapy; radical surgery; conservative treatment; targeted therapy
(This special issue belongs to the Section Oncology)
Clinical Challenges in Endocrine Oncology
edited by
submission deadline 15 Oct 2026 | 1 articles | Viewed by 200 | Submission Open
Keywords: neuroendocrine tumors; thyroid cancer; adrenocortical carcinoma; pituitary adenoma; multiple endocrine neoplasia (MEN); hormone-secreting tumors
(This special issue belongs to the Section Endocrinology & Metabolism)
Clinical and Surgical Treatment for Orthopedic Trauma
edited by Mihnea Ioan Gabriel Popa
submission deadline 15 Oct 2026 | Viewed by 176 | Submission Open
Keywords: orthopedic surgery; orthopedic trauma; trauma surgery; musculoskeletal oncology; musculoskeletal biomaterials; infection management; complication management
(This special issue belongs to the Section Orthopedics)
Urologic Disorders: Advances in Diagnosis and Therapy
edited by Carmen Gonzalez-Enguita and
submission deadline 15 Oct 2026 | Viewed by 168 | Submission Open
Keywords: prostatic hyperplasia; urinary incontinence; urothelial carcinoma; minimally invasive surgery; kidney stone; urinary tract infection
(This special issue belongs to the Section Nephrology & Urology)
Cardiac Surgery: Current Clinical Challenges and New Perspectives
edited by Sadeq Ali-Hasan-Al-Saegh and
submission deadline 15 Oct 2026 | Viewed by 154 | Submission Open
Keywords: cardiac surgery; surgical challenges; innovations in cardiology; minimally invasive techniques; robotic-assisted surgery; artificial intelligence in cardiac surgery; postoperative management; quality improvement in cardiac surgery
(This special issue belongs to the Section Cardiology)
Clinical Advances in Liver Transplantation and Organ Perfusion
edited by Franziska A. Meister
submission deadline 15 Oct 2026 | Viewed by 149 | Submission Open
Keywords: liver transplantation; extended criteria donors; ischemia– reperfusion injury; graft dysfunction; organ preservation; machine perfusion; normothermic perfusion; hypothermic perfusion; transplant outcomes
(This special issue belongs to the Section General Surgery)
Advances in Coronary Heart Disease: From Diagnosis to Long-Term Care
edited by and Cristian Leva
submission deadline 15 Oct 2026 | Viewed by 138 | Submission Open
Keywords: coronary heart disease; myocardial ischemia; percutaneous coronary intervention; coronary artery bypass surgery; left ventricular reconstruction; coronary diagnostic; coronary microvascular dysfunction; personalized medicine
(This special issue belongs to the Section Cardiology)
Clinical Management of Pemphigus
edited by
submission deadline 15 Oct 2026 | Viewed by 135 | Submission Open
Keywords: pemphigus; pemphigus IgA; paraneoplastic pemphigus; cell– cell contact proteins and diagnostic procedures; novel therapies
(This special issue belongs to the Section Dermatology)
Otolaryngologic Clinical Findings and Management Across the Spectrum of Idiopathic Intracranial Hypertension
edited by Bülent Mamikoǧlu
submission deadline 15 Oct 2026 | Viewed by 112 | Submission Open
Keywords: idiopathic intracranial hypertension; intracranial pressure dysregulation; pulsatile tinnitus; venous sinus stenosis; CSF– inner ear coupling; vestibular migraine; dizziness and vertigo; aural fullness; glymphatic system; Chiari malformation; otologic manifestations of IIH; endovascular treatment; acetazolamide therapy
(This special issue belongs to the Section Otolaryngology)
Current Challenges and Innovations in Spine Deformity: Biomechanics, Imaging and AI-Driven Analysis
edited by Dong-Ho Kang
submission deadline 16 Oct 2026 | 3 articles | Viewed by 3471 | Submission Open
Keywords: spinal deformity; cervical deformity; biomechanics; postural alignment; sagittal imbalance; medical imaging; radiographic analysis; artificial intelligence; machine learning; deep learning; phenotyping; computer-assisted diagnosis; predictive modeling; surgical planning
(This special issue belongs to the Section Orthopedics)
Haemodialysis and Peritoneal Dialysis: Current Clinical Practices and Innovations
edited by
submission deadline 16 Oct 2026 | Viewed by 366 | Submission Open
Keywords: haemodialysis; peritoneal dialysis; end-stage kidney disease; chronic kidney disease; nephrology
(This special issue belongs to the Section Nephrology & Urology)
Contemporary Treatment of Complement-Mediated Diseases
edited by and Danko Milošević
submission deadline 16 Oct 2026 | Viewed by 166 | Submission Open
Keywords: complement-mediated diseases; complement activation; atypical hemolytic uremic syndrome; C3 glomerulopathy; thrombotic microangiopathy; complement inhibitors; kidney transplantation; antibody-mediated rejection; complement dysregulation; genetic testing; kidney failure; dialysis; kidney transplantation; kidney allograft rejection
(This special issue belongs to the Section Nephrology & Urology)
Advances and Clinical Updates in the Gastrointestinal and Abdominal Diseases
edited by Elissavet Anestiadou, Savvas Symeonidis and Ioannis Mantzoros
submission deadline 19 Oct 2026 | Viewed by 188 | Submission Open
Keywords: gastrointestinal surgery; minimally invasive surgery; enhanced recovery; digestive oncology; inflammatory bowel disease; abdominal wall reconstruction; biomaterials; perioperative management
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Management of Pediatric Heart Diseases
edited by
submission deadline 20 Oct 2026 | 8 articles | Viewed by 8587 | Submission Open
Keywords: pediatric heart diseases; children; pediatric cardiology; congenital heart disease; clinical management; congenital heart surgery; outcome
(This special issue belongs to the Section Clinical Pediatrics)
Chronic Disease Management and Rehabilitation in Older Adults
edited by
submission deadline 20 Oct 2026 | 5 articles | Viewed by 8424 | Submission Open
Keywords: chronic disease; older adults; geriatric rehabilitation; holistic physiotherapy; physical activity; health outcomes; elderly people; geriatric care; health promotion
(This special issue belongs to the Section Geriatric Medicine)
Application of Echocardiography in the Diagnosis and Management of Cardiac Diseases
edited by and
submission deadline 20 Oct 2026 | 5 articles | Viewed by 6603 | Submission Open
Keywords: echocardiography; cardiac diseases; 3D echo; stress; myocardial strain; intracardiac; subclinical cardiac disease
(This special issue belongs to the Section Cardiology)
Acute Ischemic Stroke Management Strategies
edited by
submission deadline 20 Oct 2026 | 5 articles | Viewed by 6460 | Submission Open
Keywords: mechanical thrombectomy; leptomeningeal collateral circulation; neuroprotection; reperfusion injury; ischemic penumbra
(This special issue belongs to the Section Clinical Neurology)
Clinical Management of Corneal Diseases
edited by Hyeck Soo Son
submission deadline 20 Oct 2026 | 3 articles | Viewed by 6440 | Submission Open
Keywords: corneal diseases; keratoconus; corneal dystrophy; corneal ectasia; corneal transplantation; DMEK; DSAEK; kerato-prosthesis; crosslinking; ICRS; CAIRS; Bowman layer transplantation; treatment outcomes; clinical management
(This special issue belongs to the Section Ophthalmology)
Acute Myeloid Leukemia: Latest Advances in Diagnostics, Therapeutic Strategies and Clinical Management: 2nd Edition
edited by Michael D. Diamantidis
submission deadline 20 Oct 2026 | 5 articles | Viewed by 6307 | Submission Open
Keywords: ELN; ICC and WHO 2022 AML classifications; molecular AML diagnostics; AML biology; measurable residual disease (MRD); novel targeted AML therapies; AML immunotherapies; hematopoietic stem cell transplantation (HSCT)
(This special issue belongs to the Section Hematology)
Clinical Management of Patients with Heart Failure: 3rd Edition
edited by
submission deadline 20 Oct 2026 | 7 articles | Viewed by 5933 | Submission Open
Keywords: acute heart failure; chronic heart failure; treatment options; management of heart failure; lifestyle changes; diagnosis of heart failure
(This special issue belongs to the Section Cardiovascular Medicine)
Recent Developments in Hearing and Balance Disorders: 2nd Edition submission deadline 20 Oct 2026 | 4 articles | Viewed by 5832 | Submission Open
Keywords: ear; otology; audiology; hearing disorders; deafness; hearing loss; autoimmunity; ENT; inflammation; vertigo; imbalance
(This special issue belongs to the Section Otolaryngology)
Clinical Challenges and Innovations in Cochlear Implantation and Hearing Rehabilitation
edited by
submission deadline 20 Oct 2026 | 8 articles | Viewed by 5595 | Submission Open
Keywords: cochlear implant outcomes; clinical efficiency; barriers to care; cochlear implant surgery; cochlear implant referral; cochlear implant evaluation; cochlear implant candidacy; rehabilitation; rehabilitation strategies; quality of life
(This special issue belongs to the Section Otolaryngology)
Clinical Update on Thoracic Trauma
edited by
submission deadline 20 Oct 2026 | 6 articles | Viewed by 4657 | Submission Open
Keywords: flail chest; isolated sternal fractures; manubrio-sternal dislocation; pneumothorax; hemothorax; thoracic aortic injury; heart and pulmonary vessels lesion; intercostal artery injury; diaphragm rupture; thoracoabdominal hernia; chylothorax; esophageal perforation
(This special issue belongs to the Section Respiratory Medicine)
Clinical Insights and Emerging Techniques in Interventional Cardiology
edited by
submission deadline 20 Oct 2026 | 1 articles | Viewed by 4397 | Submission Open
Keywords: percutaneous coronary intervention; coronary imaging; intravascular ultrasound; IVUS; computed tomography; optical coherence tomography; OCT; chronic total occlusions; drug-coated balloons; bifurcations; calcified coronary lesions; rotational atherectomy; intravascular lithotripsy; acute coronary syndromes; chronic coronary syndromes
(This special issue belongs to the Section Cardiology)
Novel Insights into Clinical Diagnosis and Management of Degenerative Cervical Myelopathy
edited by , Francesco Costa and Filippo Maria Polli
submission deadline 20 Oct 2026 | 2 articles | Viewed by 3967 | Submission Open
Keywords: degenerative cervical myelopathy (DCM); cervical spondylotic myelopathy (CSM); cervical spinal stenosis; cervical cord compression; MRI of the cervical spine; cervical spine surgery; physical therapy; rehabilitation; ossification of the posterior longitudinal ligament (OPLL); cervical deformity (e.g.; kyphosis and lordosis); patient-reported out-comes; surgical outcome prediction
(This special issue belongs to the Section Clinical Neurology)
Clinical Implications of Pupil Function: Optical Quality, Visual Performance, and Neurological Biomarkers
edited by Pablo De Gracia and Héctor E. Soriano Baron
submission deadline 20 Oct 2026 | 1 articles | Viewed by 3753 | Submission Open
Keywords: pupil function; visual performance; intraocular lens (IOL) optimization; pupillometry diagnostics; neuro-ophthalmic biomarkers
(This special issue belongs to the Section Ophthalmology)
Advances in Maternal Fetal Medicine
edited by and Anna Franca Cavaliere
submission deadline 20 Oct 2026 | 3 articles | Viewed by 3680 | Submission Open
Keywords: drugs use during pregnancy; fetal treatment; pregnancy complications; infectious diseases; neonatal poor adaptation syndrome
(This special issue belongs to the Section Obstetrics & Gynecology)
Intrarenal Surgery for Kidney Stones and Other Kidney Diseases
edited by Razvan Multescu
submission deadline 20 Oct 2026 | 4 articles | Viewed by 3467 | Submission Open
Keywords: intrarenal surgery; flexible ureteroscopy; percutaneous nephrolithotomy (PCNL); Mini-PCNL; thulium laser; ureteral access sheaths; flexible and navigable suction (FANS); upper urinary tract urothelial tumors
(This special issue belongs to the Section Nephrology & Urology)
Skin Cancer: Prevention, Diagnosis, Quality of Life and Treatment Outcomes
edited by Athanassios A. Kyrgidis and
submission deadline 20 Oct 2026 | 4 articles | Viewed by 3261 | Submission Open
Keywords: skin cancer; melanoma; squamous cell carcinoma; basal cell carcinoma; clinical biomarkers; dermoscopy; quality of life
(This special issue belongs to the Section Dermatology)
Recent Advances in Endocrine Surgery—2nd Edition
edited by
submission deadline 20 Oct 2026 | 2 articles | Viewed by 2962 | Submission Open
Keywords: endocrine surgery; thyroid; thyroid cancer; parathyroid; parathyroidectomy; adrenal glands; disorders of hepatobiliary and gastrointestinal tract
(This special issue belongs to the Section General Surgery)
Heart Failure: Treatment and Clinical Perspectives
edited by Geza Halasz, Domenico Gabrielli and Francesco Grigioni
submission deadline 20 Oct 2026 | 4 articles | Viewed by 2941 | Submission Open
Keywords: heart failure; chronic heart failure; acute heart failure; treatment; cardiac imaging; diagnostics; patient outcomes; prognosis
(This special issue belongs to the Section Cardiology)
New Insights into Retinal Diseases
edited by Fabio Scarinci and Giulio Pocobelli
submission deadline 20 Oct 2026 | 4 articles | Viewed by 2743 | Submission Open
Keywords: optical coherence tomography; optical coherence tomography angiography; vitreoretinal diseases; retinal imaging analysis; biomarkers; segmentation; retinal ischemia; retinal blood flow; choroidal blood flow
(This special issue belongs to the Section Ophthalmology)
New Advances and Clinical Outcomes of Endocrinology
edited by Stefana Catalina Bilha and
submission deadline 20 Oct 2026 | 2 articles | Viewed by 2700 | Submission Open
Keywords: endocrinology; obesity; metabolic and bone disease; chronic conditions
(This special issue belongs to the Section Endocrinology & Metabolism)
Pediatric Dentistry: Real-World Clinical Insights submission deadline 20 Oct 2026 | 2 articles | Viewed by 2635 | Submission Open
Keywords: pediatric dentistry; minimally invasive dentistry; new technologies; biomaterials; innovative management approaches; caries management; pulp management; dental trauma; molar incisor hypomineralization; public health services research; epidemiological research; translational research
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Updates in Imaging of Musculoskeletal Diseases submission deadline 20 Oct 2026 | 4 articles | Viewed by 2589 | Submission Open
Keywords: musculoskeletal imaging; ultrasound; magnetic resonance; sport imaging; rheumatology; nerve imaging
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Orofacial Pain: Innovations in Treatment Modalities and Patient Care
edited by
submission deadline 20 Oct 2026 | 1 articles | Viewed by 2336 | Submission Open
Keywords: orofacial pain; treatment; patient care; oral dysfunction; chronic pain; burning mouth syndrome; temporomandibular joint pain: oral cenesthopathy; atypical odontalgia; phantom bite syndrome
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Hip and Knee Arthroplasty: Update on Clinical Management
edited by Maximilian F. Kasparek
submission deadline 20 Oct 2026 | 4 articles | Viewed by 2301 | Submission Open
Keywords: total hip arthroplasty (THA); total knee arthroplasty (TKA); revision arthroplasty; implant fixation; cemented; cementless; hybrid; alignment in TKA; mechanical alignment; kinematic alignment; restricted kinematic alignment; functional alignment; navigation; robotic-assisted surgery; patient-specific instrumentation; additive manufacturing; 3D printing; personalized implant
(This special issue belongs to the Section Orthopedics)
New Challenges and Perspectives in Surgical Treatment of Spinal Deformity
edited by Jung-Hee Lee
submission deadline 20 Oct 2026 | 4 articles | Viewed by 2124 | Submission Open
Keywords: adult spinal deformity; decompensation; kyphosis; lateral lumbar interbody fusion; orthopedic surgery; osteotomy; proximal junctional kyphosis; rod fracture
(This special issue belongs to the Section Orthopedics)
Periodontology and Dental Implants: State of the Art and Future Perspectives
edited by Magda Mensi and
submission deadline 20 Oct 2026 | 2 articles | Viewed by 2013 | Submission Open
Keywords: periodontology; dental implants; regenerative dentistry; peri-implant diseases; digital dentistry; implant surface modifications; tissue engineering; oral microbiome; risk assessment; personalized treatment
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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