Glaucoma Surgery: Current Challenges and Future Perspectives
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 8
Special Issue Editors
Interests: glaucoma; MIGS; ophthalmic therapies; drug delivery
Interests: glaucoma; cataract; ophthalmic genetics
Interests: glaucoma; adult and childhood glaucoma; MIGS; epidemiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Glaucoma surgery faces several challenges that impact effectiveness and patient outcomes. The variability in surgical success rates is influenced by factors such as individual anatomy and pathophysiology. Post-operative scarring remains a very important obstacle for long-term surgical success of external filtration procedures.
Advances in biomaterials and targeted gene therapy seek to reduce scarring and improve performance of the surgical implants or trabeculectomy. Emerging imaging and AI may transform glaucoma management by enabling more personalized and predictable surgical outcomes. Advanced imaging techniques using optical coherence tomography provide detailed visualization of ocular structures, aiding precise surgical planning. It is anticipated that AI-driven models can identify patients at higher risk of complications and optimize timing and choice of surgery. Overall, integrating imaging and AI enhances accuracy, individualization, and prognosis in surgery, ultimately leading to better patient outcomes and more efficient, targeted treatments tailored to individual patients.
Future perspectives in glaucoma surgery aim to enhance safety, efficacy, and patient quality of life. This will include personalized surgical approaches based on genetic and biometric patient data, combined with advancements in imaging, biomaterials and regenerative medicine. Integrating technological innovations and personalized medicine may provide safer and more effective surgical options for glaucoma management in the future.
Prof. Dr. Tina Tzee Ling Wong
Prof. Dr. Kuldev Singh
Prof. Dr. Esther M. Hoffmann
Guest Editors
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Keywords
- glaucoma
- filtration surgery
- trabeculectomy
- MIGS
- scarring
- anti-metabolites
- wound healing
- anti-fibrotics
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