Beyond the Kidney: Managing Chronic Kidney Disease in the Era of Cardio-Metabolic-Kidney Syndrome
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 17
Special Issue Editors
Interests: clinical nephrology; chronic kidney disease; ADPKD; physical activity; DKD-MBD; kidney stones
Special Issue Information
Dear Colleagues,
This Special Issue aims to address the evolving landscape of chronic kidney disease (CKD) management within the broader framework of cardio-metabolic-kidney (CMK) syndrome. Despite advances in pharmacological therapies—such as RAAS inhibitors, SGLT2 inhibitors, and MRAs—key challenges remain, including suboptimal implementation of lifestyle interventions and fragmented care across specialties. The growing recognition of CMK syndrome underscores the need to move beyond organ-specific treatment and adopt a multidisciplinary strategy targeting shared risk factors like hypertension, obesity, dyslipidemia, and insulin resistance.
This Special Issue welcomes original research and reviews focused on integrated therapeutic approaches, including pharmacologic innovations, nutritional and exercise-based interventions, patient-centered care models, and emerging biomarkers or digital tools for early detection. By bringing together nephrology, cardiology, endocrinology, and primary care perspectives, this Special Issue seeks to mobilize a collaborative research community to overcome systemic gaps and improve patient outcomes.
Researchers and clinicians are encouraged to contribute studies that reflect the complexity of CKD within the CMK context, helping to build a more effective and inclusive model of chronic disease management.
Dr. Maria Amicone
Prof. Dr. Antonio Pisani
Guest Editors
Manuscript Submission Information
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Keywords
- chronic kidney disease
- disease-modifying therapy
- physical exercise
- cardio-metabolic-kidney syndrome
- SGLT2 in-hibitors
- MRA
- renal nutrition
- innovative therapies
- low protein diet
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