Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
2.9
Journals
JCM
Special Issues
Pregnancy and Delivery Complications: Bridging Research and Clinical Practice
jcm-logo
Submit to Special Issue Submit Abstract to Special Issue Review for JCM Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Pregnancy and Delivery Complications: Bridging Research and Clinical Practice

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: 25 September 2026 | Viewed by 1146

Special Issue Editors

Dr. Maria Patricia Roman

E-Mail Website
Guest Editor
Mother and Child Department, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania
Interests: urogynaecology; childbirth pelvic floor trauma; pelvic floor ultrasound; obstetric fistula; obstetrics
Dr. Andrei Mihai Malutan

E-Mail Website
Guest Editor
Mother and Child Department, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania
Interests: pelvic pathology; prenatal ultrasonography; pregnancy complications; twin pregnancy; placental disorders
Dr. Răzvan Ciortea

E-Mail Website
Guest Editor
Mother and Child Department, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania
Interests: maternal-fetal medicine; obstetrics; laparoscopic gynaecology; fetal ultrasound; high-risk pregnancy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue seeks to advance contemporary obstetric care by disseminating cutting-edge research and expert perspectives on individualized pregnancy and childbirth management. By compiling high-quality original studies, systematic reviews, and expert commentaries, we aim to conduct the following:

  • Promote innovative strategies for risk stratification and outcome optimization in maternal–fetal medicine.
  • Address unresolved clinical challenges through multidisciplinary research.
  • Provide actionable insights to refine clinical protocols and improve perinatal health globally.

Submission topics include, but are not limited to, the following:

Maternal–fetal and perinatal complications

  • Hypertensive disorders of pregnancy; gestational diabetes mellitus; thyroid dysfunction; autoimmune diseases in pregnancy; placental disorders; preterm birth prevention; multiple gestation complications; pregnancy-associated sepsis; birth dystocia chorioamnionitis; ART-related complications; obesity in pregnancy; birth asphyxia; and neonatal sepsis.

Childbirth-related pelvic floor disorders

  • Childbirth perineal trauma (e.g., obstetric anal sphincter injuries, obstetric fistula); pelvic organ prolapse/urinary incontinence post vaginal delivery; and transperineal ultrasound.

Emerging research areas

  • Microbiome and pregnancy complications; AI applications in predicting pregnancy complications; environmental exposures (endocrine disruptors and air pollution) and adverse outcomes; and patient-reported outcomes and outcome measures (PROs/PROMs) for assessing pregnancy and childbirth care quality.

We would like to invite you to contribute to this Special Issue, which hopes to collectively advance maternal and neonatal health through innovation, evidence, and collaboration.

Dr. Maria Patricia Roman
Dr. Andrei Mihai Malutan
Dr. Răzvan Ciortea
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • maternal–fetal medicine
  • obstetric complications
  • perinatal health
  • pelvic floor disorders
  • childbirth perineal trauma
  • risk stratification
  • patient-reported outcomes
  • patient-reported outcome measures

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

15 pages, 257 KB  
Article
Pregnancy Complications in Uterine Anomalies—A Pilot Study
by Claudiu Voic, Melinda Ildiko Mitranovici, Septimiu Voidazan, Cezara Maria Mureşan and Elena Silvia Bernad
J. Clin. Med. 2026, 15(8), 2827; https://doi.org/10.3390/jcm15082827 - 8 Apr 2026
Viewed by 304
Abstract
Uterine malformation represents a rare disease with a prevalence of up to 7% of the general population. Background/Objectives: Higher pregnancy complication rates have been reported in the literature; thus, in our study, we aimed to examine not only the obstetric complications encountered [...] Read more.
Uterine malformation represents a rare disease with a prevalence of up to 7% of the general population. Background/Objectives: Higher pregnancy complication rates have been reported in the literature; thus, in our study, we aimed to examine not only the obstetric complications encountered but also the psychological interventions and multidisciplinary approaches for parental counseling in our department in the context of preterm birth at the limit of viability. Methods: A retrospective pilot study was conducted on all the women in our department between 2010 and 2017 with congenital uterine malformations associated with infertility or pregnancy. In the study group, we included women with AUCs (n = 26), while the control group included pregnant women with normal uteri (n = 25) (total: n = 51), and then pregnancy complications were investigated. Results: Highly significant pregnancy complications were observed in the study group, the most important being preterm birth (p = 0.003) in comparison with the control group. Out of 26 patients with AUCs, only 14 gave birth to a live fetus compared to 22 out of the 25 with normal pregnancies, meaning that failure to give birth to a live newborn statistically significantly increased among the former group (p = 0.004). In terms of birth weight (p = 0.0001), Apgar score (p = 0.029) and intensive care unit admission (p = 0.0001), we observed significant differences between the newborns in the study group versus controls, with an impact on mental state that required psychological support. Conclusions: A clear correlation was observed in our study between uterine congenital malformations and pregnancy complications. The most common pregnancy outcome was premature delivery, with statistical significance. In addition, higher neonate admissions to the intensive care unit associated with lower Apgar scores were encountered compared with normal pregnancies. Appropriate parental counseling by obstetricians, neonatologists and psychologists could enhance pregnancy outcomes. Full article
(This article belongs to the Special Issue Pregnancy and Delivery Complications: Bridging Research and Clinical Practice)
22 pages, 766 KB  
Article
Phenotypes of Preterm Birth: A Retrospective Cohort Study from a Tertiary Romanian Centre as a Framework for Future Genomic and Proteomic Research
by Cristiana-Elena Durdu, Madalina Nicoleta Mitroiu, Bianca Margareta Salmen, Vlad Dima, Adrian Neacsu and Roxana-Elena Bohiltea
J. Clin. Med. 2026, 15(5), 1831; https://doi.org/10.3390/jcm15051831 - 27 Feb 2026
Viewed by 346
Abstract
Background/Objectives: Preterm birth (PTB) is a major global cause of neonatal morbidity and mortality, and its heterogeneous mechanisms limit the development of reliable prediction tools. Recent genomic and proteomic studies have highlighted molecular pathways involving inflammation, extracellular matrix dysfunction, and uterine activation, yet [...] Read more.
Background/Objectives: Preterm birth (PTB) is a major global cause of neonatal morbidity and mortality, and its heterogeneous mechanisms limit the development of reliable prediction tools. Recent genomic and proteomic studies have highlighted molecular pathways involving inflammation, extracellular matrix dysfunction, and uterine activation, yet their clinical integration remains limited. Defining distinct clinical phenotypes may facilitate more targeted biomarker research. Methods: We performed a retrospective cohort study of singleton spontaneous preterm births (24–36 + 6 weeks) at Filantropia Clinical Hospital, Bucharest (2022–2024). Maternal and neonatal data were extracted from electronic records. Four phenotypes were defined by presentation (preterm premature rupture of membranes—PPROM vs. contractions) and maternal inflammatory status. Statistical comparisons used ANOVA or Kruskal–Wallis tests, Chi-square tests, and logistic regression adjusted for gestational age and birth weight to assess neonatal outcomes. Results: Of 585 preterm births, 318 spontaneous singleton cases met inclusion criteria. The cohort was predominantly late preterm, with 85.5% of deliveries occurring between 34 and 36 + 6 weeks’ gestation. Four phenotypes were identified: phenotype 1 inflammatory PPROM (22.3%), phenotype 2 structural PPROM (38.1%), phenotype 3 mixed inflammatory + uterine activation (11.9%), and phenotype 4 uterotonic/endocrine phenotype (19.2%). Conclusions: These clinical phenotypes exhibited distinct maternal and neonatal patterns and correspond to mechanisms increasingly supported by genomic and proteomic studies. They may provide a practical framework for integrating clinical and molecular approaches in future PTB research. Full article
(This article belongs to the Special Issue Pregnancy and Delivery Complications: Bridging Research and Clinical Practice)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop