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Diagnosis and Treatment for Hearing Loss: Expert Views

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: 25 March 2026 | Viewed by 512

Special Issue Editors


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Guest Editor
Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences (UAMS), Little Rock, AR 72205, USA
Interests: cochlear implant; cholesteatoma; tympanoplasty; hearing loss; Ménière's disease

E-Mail Website
Guest Editor
Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences (UAMS), Little Rock, AR 72205, USA
Interests: hearing restoration; ossicular reconstruction; cochlear implant; cholesteatoma; tinnitus

Special Issue Information

Dear Colleagues,

We are pleased to introduce this Special Issue “Diagnosis and Treatment for Hearing Loss: Expert Views,” a curated collection of research and clinical insights into auditory disorders. This issue highlights a range of critical topics at the forefront of otology and audiology.

We explore novel diagnostic tools to better differentiate between sensorineural, conductive, and mixed hearing loss. Articles addressing pediatric and age-related hearing loss offer insight into early detection strategies and long-term management. We also include emerging treatments, such as regenerative therapies, cochlear implantation in challenging populations, and advancements in hearing aid and audiometric technologies. Furthermore, contributions focus on multiple forms of hearing loss, emphasizing the importance of timely intervention and interdisciplinary care.

With this Special Issue, we aim to enrich the growing body of knowledge in auditory health and foster continued innovation in diagnosing and treating hearing impairment across all age groups.

Dr. Robert A. Saadi
Dr. John L. Dornhoffer
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hearing loss
  • cochlear implants
  • hearing aid technology
  • regenerative medicine
  • diagnostic audiology

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Published Papers (1 paper)

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Review

23 pages, 800 KB  
Review
Repurposing Renin–Angiotensin System Drugs for the Treatment of Audiovestibular Disorders
by Grant Podhajsky, Kiran S. Marla, Alec P. Marticoff, Kenny Nguyen, Tanner Kempton, Sepehr Salehpour, Caden Duffy and Douglas M. Bennion
J. Clin. Med. 2026, 15(2), 743; https://doi.org/10.3390/jcm15020743 - 16 Jan 2026
Viewed by 353
Abstract
Audiovestibular disorders arising from the inner ear (e.g., hearing loss, tinnitus, vertigo) are widely prevalent in the United States. Yet, medical treatments targeting the underlying pathology of these disorders remain scarce. The practice of repurposing FDA-approved drugs for new therapeutic indications has become [...] Read more.
Audiovestibular disorders arising from the inner ear (e.g., hearing loss, tinnitus, vertigo) are widely prevalent in the United States. Yet, medical treatments targeting the underlying pathology of these disorders remain scarce. The practice of repurposing FDA-approved drugs for new therapeutic indications has become increasingly common, offering a lower risk route to treatment development with fewer barriers to implementation, as safety profiles are already established. The renin–angiotensin system (RAS) is well known for its role in blood pressure and fluid balance, and its overactivation induces acute and chronic inflammation and oxidative stress. This review discusses existing evidence and proposed otoprotective mechanisms of RAS inhibition, specifically using angiotensin II type 1 receptor blockers (ARBs), which support the repurposing of these medications as novel treatments to affect the inner ear pathologies that underlay hearing loss, tinnitus, and vertigo. Full article
(This article belongs to the Special Issue Diagnosis and Treatment for Hearing Loss: Expert Views)
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