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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Features and Management of Psychosis
edited by , and Michael Hadjulis
submission deadline 22 May 2026 | 5 articles | Viewed by 19638 | Submission Open
Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis
(This special issue belongs to the Section Mental Health)
Multiparametric Ultrasound Techniques for Liver Disease Assessments
edited by Francesco Giangregorio
submission deadline 22 May 2026 | 2 articles | Viewed by 6286 | Submission Open
Keywords: ultrasound; multiparametric ultrasound; hepatic ultrasound; contrast-enhanced ultrasound; contrast agents; diffuse hepatic diseases; focal liver lesions; hepatic elastography; liver stiffness; hepatic endosonography; hepatic EUS
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Clinical Updates on Rheumatoid Arthritis: 2nd Edition
edited by Francesca Bandinelli
submission deadline 22 May 2026 | 5 articles | Viewed by 5053 | Submission Open
Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease
(This special issue belongs to the Section Immunology & Rheumatology)
Takotsubo Syndrome: Insights into Pathophysiology, Diagnosis, and Management submission deadline 22 May 2026 | 1 articles | Viewed by 5023 | Submission Open
Keywords: takotsubo syndrome; stress cardiomyopathy; acute heart failure; cardiac imaging; catecholamine surge; myocardial dysfunction; echocardiography; biomarker discovery; cardiovascular risk; clinical management
(This special issue belongs to the Section Cardiology)
Thoracic Surgery: Recent Developments and Future Challenges
edited by and Lucio Cagini
submission deadline 22 May 2026 | 1 articles | Viewed by 3387 | Submission Open
Keywords: VATS; RATS; ERAS; sublobar resection; minimally invasive thoracic surgery; target therapy; nodule localization
(This special issue belongs to the Section Respiratory Medicine)
Thrombotic Risk and Its Management Across Diverse Clinical Settings
edited by Samuel Bogdan Todor and Ana Maria Vlǎdǎreanu
submission deadline 22 May 2026 | 2 articles | Viewed by 2980 | Submission Open
Keywords: thrombosis; thrombotic risk; hematologic disorders; thrombophilia; myeloproliferative neoplasms; antithrombotic therapy; cardiovascular diseases; biomarkers
(This special issue belongs to the Section Hematology)
Role of Platelet in Inflammation, Infection, and Immune Response submission deadline 22 May 2026 | Viewed by 1013 | Submission Open
Keywords: platelets; platelet count; dual antiplatelet therapy; inflammation; thrombosis; inflammation; hemostasis; immune response
(This special issue belongs to the Section Hematology)
Clinical Pharmacology: Adverse Drug Reactions
edited by and Ivana Mudnić
submission deadline 25 May 2026 | 11 articles | Viewed by 62588 | Submission Open
Keywords: pharmacology; adverse drug reactions; drug interactions; pharmacovigilance; drug safety
(This special issue belongs to the Section Pharmacology)
Neurovascular Diseases: Clinical Advances and Challenges
edited by , Silky Chotai, Alessandro Di Rienzo and Joham Choque-Velasquez
submission deadline 25 May 2026 | 13 articles | Viewed by 43977 | Submission Open
Keywords: neurovascular diseases; ischemic stroke; hemorrhagic stroke; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms
(This special issue belongs to the Section Clinical Neurology)
The Association Between Sleep Disorders and Metabolic and Mental Health submission deadline 25 May 2026 | 9 articles | Viewed by 26459 | Submission Open
Keywords: sleep medicine; sleep apnea; hypoxia; metabolism; mental health; women’ s health
(This special issue belongs to the Section Mental Health)
Ventilation in Critical Care Medicine: 2nd Edition
edited by Gianluca Zani
submission deadline 25 May 2026 | 3 articles | Viewed by 25545 | Submission Open
Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation
(This special issue belongs to the Section Intensive Care)
Maxillo-Facial Surgery: New Insights and Technologies in Head and Neck
edited by Federica Ruggiero
submission deadline 25 May 2026 | 7 articles | Viewed by 16924 | Submission Open
Keywords: oral and maxilla-facial surgery; orthognathic surgery; cranio-facial surgery; head and neck surgery; augmented reality; navigation; finite element modeling; virtual surgical planning; patient-specific implants
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Progress in Rehabilitation Medicine—3rd Edition
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 14455 | Submission Open
Keywords: neuro-rehabilitation; cognitive rehabilitation; spinal rehabilitation; orthopedic rehabilitation; pediatric rehabilitation; cancer rehabilitation; visceral rehabilitation; cardiac rehabilitation; pulmonary rehabilitation; renal rehabilitation; hepatic rehabilitation; rehabilitation for transplantation; fitness; peak VO2; multimorbidity and multiple disabilities (MMD); adding life to years and years to life
(This special issue belongs to the Section Clinical Rehabilitation)
Preventive, Diagnostic and Therapeutic Strategies for Abdominal Surgery Complications (Second Edition)
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 13334 | Submission Open
Keywords: complications; diagnosis; treatment; management; morbidity; abdomen; abdominal surgery; outcome; postoperative
(This special issue belongs to the Section General Surgery)
Clinical Utility of Optical Coherence Tomography in Ophthalmology: 2nd Edition submission deadline 25 May 2026 | 8 articles | Viewed by 12980 | Submission Open
Keywords: optical coherence tomography; ophthalmology; intraoperative OCT; en face OCT; wide-field OCT; retinal diseases; glaucoma; cornea; strabismus; cataract
(This special issue belongs to the Section Ophthalmology)
Clinical Diagnosis and Management of Vestibular Disorders
edited by , Mario Habek and
submission deadline 25 May 2026 | 9 articles | Viewed by 11912 | Submission Open
Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management
(This special issue belongs to the Section Otolaryngology)
Oral and Maxillofacial Surgery: Diagnosis, Management and Future Opportunities
edited by
submission deadline 25 May 2026 | 6 articles | Viewed by 11804 | Submission Open
Keywords: head and neck oncology; free flaps; oral surgery; malformative surgery; traumatology; endoscopy; preprosthetic surgery; reconstructive surgery; vascular malformations; osteonecrosis
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition
edited by Nikos Nikolettos and
submission deadline 25 May 2026 | 4 articles | Viewed by 9817 | Submission Open
Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Future Opportunities in Thoracic Surgery: The Cutting Edge: 2nd Edition
edited by
submission deadline 25 May 2026 | 2 articles | Viewed by 7933 | Submission Open
Keywords: surgical resection; immunotherapy; target therapy; thoracic surgery; thoracic oncology; lung cancer
(This special issue belongs to the Section Respiratory Medicine)
Advances in Maxillofacial Surgery—Historical and Future Perspectives and Controversies submission deadline 25 May 2026 | 6 articles | Viewed by 7094 | Submission Open
Keywords: oral oncology; facial skeleton; oral cavity; surgical approaches; head and neck; parotid tumors; jaw cysts and tumors; bone healing; patient-specific solutions; surgery planning; artificial intelligence; soft tissues; cancers and tumors of the oral cavity; microsurgery perspectives; open surgery; endoscopic surgery; trauma surgery; facial traumatology; bone and soft tissues healing after trauma; jaw deformities; orthognathic surgery today and tomorrow
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss—2nd Edition
edited by David Saceda-Corralo
submission deadline 25 May 2026 | 2 articles | Viewed by 6215 | Submission Open
Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss; frontal fibrosing alopecia
(This special issue belongs to the Section Dermatology)
Novel Insights into the Diagnosis and Management of Inflammatory Bowel Disease (IBD)
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 6128 | Submission Open
Keywords: inflammatory bowel disease; non-invasive biomarkers; abdominal ultrasonography; colonoscopy; biologic therapy; small molecules; mucosal healing; brain-gut axis; dysbiosis; colorectal dysplasia
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
The Rebirth of Ventral Skull Base Surgery through Multiportal Approaches: Endonasal, Transorbital, Transmaxillary and Transoral Routes
edited by Matteo de Notaris and Francesco Corrivetti
submission deadline 25 May 2026 | 4 articles | Viewed by 5534 | Submission Open
Keywords: skull base surgery; neuroendoscopy; neuroanatomy; multiportal approaches; technical advancements
(This special issue belongs to the Section Clinical Neurology)
Non-Small Cell Lung Cancer (NSCLC): Recent Advances in Clinical Diagnosis and Treatment
edited by
submission deadline 25 May 2026 | 7 articles | Viewed by 5100 | Submission Open
Keywords: novel screening tool; cancer biomarkers; predictive marker of immunotherapy; targeted therapy; radiotherapy; non-small cell lung cancer
(This special issue belongs to the Section Oncology)
Advances in Ablation Therapy for Atrial Fibrillation: Innovations and Clinical Applications
edited by Ioanna Koniari
submission deadline 25 May 2026 | 4 articles | Viewed by 4846 | Submission Open
Keywords: atrial fibrillation; ablation; PFA; PVI; non-thermal energy; mapping system
(This special issue belongs to the Section Cardiology)
Advances in the Clinical Management of Perioperative Anesthesia: 2nd Edition
edited by Alessia Mattei, Rita Cataldo and
submission deadline 25 May 2026 | 4 articles | Viewed by 4121 | Submission Open
Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit
(This special issue belongs to the Section Anesthesiology)
Clinical Advances of Breast Surgery and Reconstruction submission deadline 25 May 2026 | 3 articles | Viewed by 3993 | Submission Open
Keywords: breast reconstruction; autologous breast reconstruction; implant-based breast reconstruction; DIEP; LICAP; breast implant infection
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Advanced Hepato-Pancreato-Biliary Surgery: Clinical Innovations and Improved Outcomes
edited by Ahmad Mahamid and Riad Haddad
submission deadline 25 May 2026 | 3 articles | Viewed by 3675 | Submission Open
Keywords: liver surgery; pancreas surgery; biliary surgery; robotic HPB surgery; single incision surgery; prognostic biomarkers; perioperative clinical care; postoperative complications
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Modern Blood Banking and Transfusion in Clinical Practice: Second Edition
edited by
submission deadline 25 May 2026 | 3 articles | Viewed by 3629 | Submission Open
Keywords: blood transfusion therapy; patient blood management; restrictive transfusion; cell therapy; platelet transfusion
(This special issue belongs to the Section Hematology)
Clinical Highlights in Uveal Melanoma
edited by Tomasz Chorągiewicz and
submission deadline 25 May 2026 | 1 articles | Viewed by 3550 | Submission Open
Keywords: choroidal melanoma; uveal melanoma; radiotherapy; enucleation; brachytherapy
(This special issue belongs to the Section Ophthalmology)
Clinical Advances in Gastrointestinal Endoscopy
edited by and Željko Puljiz
submission deadline 25 May 2026 | 3 articles | Viewed by 3427 | Submission Open
Keywords: endoscopy; polyps; EMR; ESD; POEM; balloon dilatation; coagulation; imaging; AI imaging
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current Perspectives on the Clinical Management of Respiratory Diseases submission deadline 25 May 2026 | 3 articles | Viewed by 3389 | Submission Open
Keywords: COPD; acute exacerbations; biomarkers; clinical trials; bronchiectasis; respiratory infections
(This special issue belongs to the Section Respiratory Medicine)
New Insights in Paediatric Endocrinology
edited by
submission deadline 25 May 2026 | 4 articles | Viewed by 3278 | Submission Open
Keywords: endocrinology; pediatrics; hormones; therapy and treatment; adolescents; newborns
(This special issue belongs to the Section Clinical Pediatrics)
Clinical Updates in Reproductive Endocrinology: 2nd Edition
edited by Iwona Bojar and
submission deadline 25 May 2026 | 2 articles | Viewed by 3236 | Submission Open
Keywords: reproductive endocrinology; endocrine diseases in pregnancy; infertility; endocrine diagnostics in infertility; long-term consequences of endocrine disorders; therapy for endocrine disorders
(This special issue belongs to the Section Obstetrics & Gynecology)
Interstitial Lung Disease Secondary to Autoimmune Disorders: Recent Advances and Novel Perspectives
edited by , and Francesco Ferro
submission deadline 25 May 2026 | 1 articles | Viewed by 2985 | Submission Open
Keywords: interstitial lung disease; lung involvement; connective tissue diseases; rheumatoid arthritis; systemic vasculitis; radiomics; lung ultrasound; biomarkers; pathogenetic immunological pathways; therapeutic targets
(This special issue belongs to the Section Respiratory Medicine)
Approaches and Challenges in Oral Rehabilitation
edited by and Takayuki Kosaka
submission deadline 25 May 2026 | 2 articles | Viewed by 2499 | Submission Open
Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Prediction, Diagnosis, and Treatment of Ovarian Cancer and Other Gynecologic Tumors
edited by Eleni T. Timotheadou and Emmanouil Saloustros
submission deadline 25 May 2026 | 2 articles | Viewed by 2459 | Submission Open
Keywords: ovarian; endometrial; cervical; chemotherapy; immunotherapy; primary debulking surgery; interval debulking; fertility-sparing surgery; PARP inhibitors; radiotherapy; HIPEC; sex cord tumors; dysgerminoma; leiomyosarcoma; liquid biopsies; circulating tumor cells; ctDNA
(This special issue belongs to the Section Obstetrics & Gynecology)
Multiple Sclerosis and Demyelinating Disease: Clinical Treatment and Management
edited by Sotirios Giannopoulos
submission deadline 25 May 2026 | 2 articles | Viewed by 2316 | Submission Open
Keywords: multiple sclerosis; demyelinating disease; comorbidities; disease modifying treatments; neuromuscular disorder; myasthenia gravis
(This special issue belongs to the Section Clinical Neurology)
Innovative Technologies and Approaches in Eye Disease Management and Refractive Surgery
edited by
submission deadline 25 May 2026 | 1 articles | Viewed by 2092 | Submission Open
Keywords: multifocal intraocular lenses; femtosecond lasers; artificial intelligence; imaging; eye surgery; refractive surgery
(This special issue belongs to the Section Ophthalmology)
New Advances in Congenital Heart Disease submission deadline 25 May 2026 | 2 articles | Viewed by 1891 | Submission Open
Keywords: congenital heart disease; pediatric cardiology; adult congenital heart disease; cardiac surgery; interventional cardiology; long-term outcomes; cardiac imaging
(This special issue belongs to the Section Cardiology)
Transcatheter Aortic Valve Implantation- Clinical Management and Future Challenges
edited by Mohamed Farag
submission deadline 25 May 2026 | 2 articles | Viewed by 1863 | Submission Open
Keywords: transcatheter aortic valve implantation; TAVI; bicuspid aortic valve; small annulus; prosthesis– patient mismatch; coronary reaccess; valve-in-valve TAVI; leaflet modification
(This special issue belongs to the Section Cardiovascular Medicine)
High-Risk Neuroblastoma and Rhabdoid Tumors: New Clinical Insights and Challenges (Second Edition)
edited by and Johannes Hubertus Schulte
submission deadline 25 May 2026 | 1 articles | Viewed by 1824 | Submission Open
Keywords: neuroblastoma; rhabdoid tumor; autologous stem cell transplantation; allogeneic stem cell transplantation immunotherapy; anti-GD2 antibody; targeted therapy; CAR T-cells
(This special issue belongs to the Section Oncology)
Anemia: Clinical Updates in Diagnosis, Management, and Treatment submission deadline 25 May 2026 | 2 articles | Viewed by 1794 | Submission Open
Keywords: anemia; diagnostic tools; hematology; artificial intelligence; targeted therapy; hereditary hemolytic anemia
(This special issue belongs to the Section Hematology)
Clinical Advances in the Management of Abdominal and Thoracoabdominal Aortic Aneurysms
edited by
submission deadline 25 May 2026 | 3 articles | Viewed by 1558 | Submission Open
Keywords: abdominal aneurysm; thoraco-abdominal; computed-tomography angiography; branched endograft; branched endovascular aortic repair; fenestrated endograft; open surgery; 3-D printing
(This special issue belongs to the Section Vascular Medicine)
Anesthesia and Perioperative Management of Organ Transplants
edited by and Ji-Hye Kwon
submission deadline 25 May 2026 | 1 articles | Viewed by 1151 | Submission Open
Keywords: liver transplantation; coagulation; reperfusion syndrome; perioperative evaluation; coronary artery disease; CDC; DBD; living donor liver transplant; pulmonary evaluation; hepatorenal syndrome; portopulmonary hypertension
(This special issue belongs to the Section Anesthesiology)
Epilepsy and Cerebrovascular Disorders
edited by
submission deadline 25 May 2026 | 1 articles | Viewed by 855 | Submission Open
Keywords: epilepsy; cerebrovascular disorders; stroke; post-stroke epilepsy; neuroinflammation; neuroimaging; electroenceph-alography; biomarkers; antiepileptic treatment; translational neuroscience
(This special issue belongs to the Section Clinical Neurology)
Advances in the Clinical Management of Diabetic Retinopathy
edited by
submission deadline 25 May 2026 | 1 articles | Viewed by 762 | Submission Open
Keywords: retinal imaging; clinical outcomes; optical coherence tomography (OCT); vitrectomy; blood flow
(This special issue belongs to the Section Ophthalmology)
Clinical Advances and Challenges in Vascular and Endovascular Medicine: 2nd Edition
edited by
submission deadline 25 May 2026 | Viewed by 320 | Submission Open
Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies
(This special issue belongs to the Section Vascular Medicine)
Acute and Chronic Heart Failure: Clinical Updates and Perspectives—2nd Edition
edited by Luigi Cappannoli and Cristina Aurigemma
submission deadline 25 May 2026 | Viewed by 285 | Submission Open
Keywords: acute heart failure; chronic heart failure; devices; drug therapy; percutaneous ventricular assist devices; cardiogenic shock; arrhythmias; ischemic heart disease
(This special issue belongs to the Section Cardiovascular Medicine)
Musculoskeletal Imaging and Intervention: 2nd Edition submission deadline 25 May 2026 | Viewed by 281 | Submission Open
Keywords: ultrasound; invasive physiotherapy; minimally invasive surgical procedures; magnetic resonance; image analysis
(This special issue belongs to the Section Nuclear Medicine & Radiology)
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