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State-of-the-Art Innovations in Oral and Maxillofacial Surgery
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State-of-the-Art Innovations in Oral and Maxillofacial Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 4439

Special Issue Editors

Prof. Dr. Marcin Kozakiewicz

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Guest Editor
Department of Maxillofacial Surgery, Medical University of Lodz, 113 Żeromskiego, 90-549 Lodz, Poland
Interests: osteosynthesis techniques of the mandibular head; treatment of mandibular condylar fractures; orbital surgery; maxillofacial implantology; digital analysis of biomedical images and alveolar bone remodeling after functional loading of dental implants
Dr. Katarzyna Bogusiak

E-Mail
Guest Editor Assistant
Department of Maxillofacial Surgery, Medical University of Lodz, 113 Żeromskiego, 90-549 Lodz, Poland
Interests: head and neck oncology; the molecular pathogenesis and biology of oral cancer; microvascular and reconstructive surgery

Special Issue Information

Dear Colleagues,

The field of oral and maxillofacial surgery has undergone profound transformations in recent decades, fueled by the rapid advancements in medical technology, surgical techniques, and biological materials.

This transformation has been particularly noteworthy in the intricate interplays among oral surgery, maxillofacial surgery, and oral pathology, which have emerged as a cornerstone in the comprehensive management of oro-maxillary disorders.

In this Special Issue, we hope to present novel scientific results, clinical experiences, and future directions for discovering the beauty of oral and maxillofacial surgery. You are cordially invited to submit scientific papers on craniofacial traumatology, deformity treatment and corrective surgery, dentoalveolar surgery, oral implantology and maxillofacial infection control, head and neck oncological surgery, as well as their associated fields.

Prof. Dr. Marcin Kozakiewicz
Guest Editor

Dr. Katarzyna Bogusiak
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral surgery
  • maxillofacial surgery
  • traumatology
  • orthognatic surgery
  • infections
  • oncology
  • diagnostics
  • treatment
  • implantology
  • augmentation
  • imaging
  • computer-assisted techniques

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (6 papers)

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9 pages, 189 KiB  
Article
Clinical Photography in Orthodontic Practice: Insights from a Nationwide Survey in Spain
by Brezo Suárez-Solís, Carlota Suárez-Fernández, Juan Suárez-Solís, Alberto Badía, Maider Olabarria and Teresa Cobo
J. Clin. Med. 2025, 14(6), 1984; https://doi.org/10.3390/jcm14061984 - 14 Mar 2025
Viewed by 517
Abstract
Background/Objectives: Clinical photography is an essential component of orthodontic records, alongside radiographs, dental scanners, and cone beam computed tomography. However, neither the American Association of Orthodontists nor the Spanish Society of Orthodontics provides a standardized protocol for dental photography. This study aimed to [...] Read more.
Background/Objectives: Clinical photography is an essential component of orthodontic records, alongside radiographs, dental scanners, and cone beam computed tomography. However, neither the American Association of Orthodontists nor the Spanish Society of Orthodontics provides a standardized protocol for dental photography. This study aimed to evaluate the current practices, challenges, and training needs related to clinical photography among orthodontists in Spain. Methods: A cross-sectional survey was designed using Google Forms® and distributed to orthodontists practising in Spain. A sample size of 303 participants was calculated (95% confidence level; 0.1 precision). The questionnaire covered photographic practices, equipment usage, self-assessed skills, interest in training, and legal considerations. Descriptive and inferential analyses were performed using R software (significance level 0.05; version 4.4.1). Results: A total of 304 valid responses were analyzed, with a predominance of female participants (77.96%) and a mean age of 37.54 years (SD: 9.08). Digital single-lens reflex (DSLR) cameras with macro lenses and ring flashes were the most used equipment (68.09%). The primary software for cropping and editing images were Windows Photos (28.95%) and MacOS Photos (16.12%). Male participants rated their photography skills higher than female participants (p = 0.003), and those with full-time orthodontic training considered their skills better than those with other types of training (p = 0.014). Photography was most valued for diagnosis in the exclusive orthodontics group (p = 0.019). Additionally, 75.99% of respondents expressed interest in improving their photography skills through specialized courses. Conclusions: This study highlights significant variability in photographic practices among orthodontists in Spain. The findings emphasize the need for standardized photography protocols to enhance diagnostic accuracy, clinical documentation, and professional training. Full article
(This article belongs to the Special Issue State-of-the-Art Innovations in Oral and Maxillofacial Surgery)
16 pages, 2260 KiB  
Article
Profile of the Main Representatives of Sphingolipid Metabolism in the Maxillary and Mandibular Periosteum of Patients with Dentofacial Deformities After Osteosynthesis Using Titanium Implants
by Bożena Antonowicz, Agnieszka Błachnio-Zabielska, Urszula Chlabicz, Mateusz Maciejczyk, Jan Borys, Kamila Łukaszuk, Sara Zięba, Roberto Lo Giudice, Giuseppe Lo Giudice, Mariusz Szuta and Anna Zalewska
J. Clin. Med. 2025, 14(6), 1929; https://doi.org/10.3390/jcm14061929 - 13 Mar 2025
Viewed by 385
Abstract
Background/Objectives: The objective of this study was to analyze the profiles of sphingosine (Sph), sphinganine (SPA), sphingosine-1-phosphate (S1P), and ceramides (C14 Cer, C16 Cer, C18:1 Cer, C18 Cer, C20 Cer, C22 Cer, C24:1 Cer, and C24 Cer), along with caspases (CAS-3, CAS-6, and [...] Read more.
Background/Objectives: The objective of this study was to analyze the profiles of sphingosine (Sph), sphinganine (SPA), sphingosine-1-phosphate (S1P), and ceramides (C14 Cer, C16 Cer, C18:1 Cer, C18 Cer, C20 Cer, C22 Cer, C24:1 Cer, and C24 Cer), along with caspases (CAS-3, CAS-6, and CAS-9), in serum and in the periosteum of the maxilla and mandible in patients with dentofacial deformities undergoing treatment with titanium fixations (miniplates and miniscrews). Methods: The study group comprised 20 patients who underwent bilateral jaw osteotomy due to dentofacial deformities. The osteotomy segments were stabilized with titanium alloy miniplates and screws. The control group consisted of 20 patients who had not yet received surgical treatment for maxillofacial defects. Results: Sphinganine (SPA) and ceramide C22 (C22 Cer) were the only compounds found to be significantly elevated in the serum of the study group compared to the control group. The concentrations of Sph, SPA, C14 Cer, C16 Cer, C18 1 Cer, C18 Cer, C22 Cer, C24 1 Cer, C24 Cer, and S1P were significantly lower in the maxillary periosteum of patients in the study group compared to those in the control group. The concentration of C20 Cer was significantly higher in the maxillary periosteum of patients in the study group compared to the control group. In contrast, the concentrations of Sph, SPA, C14 Cer, C16 Cer, C18 1 Cer, C22 Cer, C24 1 Cer, and C24 Cer were significantly lower in the mandibular periosteum of the study group compared to the control group. The concentrations of C20 Cer and S1P were significantly elevated in the mandibular periosteum of patients in the study group compared with the control group. The activity of CAS-3 was significantly higher in the mandibular periosteum of patients in the study group compared to those in the control group. Conclusions: Titanium fixations induce local changes in the sphingolipid profile within the periosteum of the maxilla and mandible, while no systemic impact on this metabolism was observed. Full article
(This article belongs to the Special Issue State-of-the-Art Innovations in Oral and Maxillofacial Surgery)
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11 pages, 6372 KiB  
Article
The Evaluation of Oral Health in Patients Undergoing Dental Treatment During the COVID-19 Pandemic
by Bartosz Bielecki-Kowalski, Oliwia Kowalczyk, Maja Podziewska, Paulina Agier, Aleksandra Kroc-Szczepkowska and Marcin Kozakiewicz
J. Clin. Med. 2024, 13(23), 7216; https://doi.org/10.3390/jcm13237216 - 28 Nov 2024
Viewed by 959
Abstract
Background: The association between oral cavities and the SARS-CoV-2 virus is an issue commonly analyzed and studied. In our study, the relationship between the dental status and social environment of patients receiving treatment during the coronavirus pandemic and COVID-19 vaccination was analyzed. [...] Read more.
Background: The association between oral cavities and the SARS-CoV-2 virus is an issue commonly analyzed and studied. In our study, the relationship between the dental status and social environment of patients receiving treatment during the coronavirus pandemic and COVID-19 vaccination was analyzed. Methods: This retrospective study was based on 2034 dental records obtained from the Institute of Dentistry of the Medical University of Lodz. The collected data pertaining to caries enabled the assessment of the oral cavity health of individual patients and could be compared with the undergoing vaccination against COVID-19. Results: The statistically significant results showed that unvaccinated patients compared to vaccinated patients had more teeth with caries, less teeth extracted due to caries, more teeth in total, and lower DMFT and dental treatment indexes. It was shown that, with increased age, the value of the DMFT index increases. Statistically significant differences between patients living in rural and urban areas were as follows: rural residents showed lower DMFT and filling indexes. Conclusions: No direct relationship between the vaccination of patients and oral health has been proven. Statistically, the group of vaccinated patients are significantly older than the unvaccinated, and the significant differences between the above groups are most likely due to the difference in the average age of patients in the two groups. Our study showed a lower average DMFT index and a higher treatment intensity index in people from the countryside compared to those living in a large city. In this respect, our study stands in opposition to the existing research findings. Full article
(This article belongs to the Special Issue State-of-the-Art Innovations in Oral and Maxillofacial Surgery)
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22 pages, 15011 KiB  
Article
The Pattern of Cytokines, Chemokines, and Growth Factors of the Maxillary and Mandibular Periosteum After Exposure to Titanium Fixations—Ti6Al4V
by Bożena Antonowicz, Mateusz Maciejczyk, Jan Borys, Kamila Łukaszuk, Sara Zięba, Edyta Gołaś, Małgorzata Żendzian-Piotrowska and Anna Zalewska
J. Clin. Med. 2024, 13(23), 7064; https://doi.org/10.3390/jcm13237064 - 22 Nov 2024
Cited by 2 | Viewed by 688
Abstract
Objectives: Titanium miniplates and screws are commonly used in the surgical management of dentofacial deformities. Despite the opinion of the biocompatibility of these bone fixations, some patients experience symptoms of chronic inflammation around titanium implants even many years after their application. The aim [...] Read more.
Objectives: Titanium miniplates and screws are commonly used in the surgical management of dentofacial deformities. Despite the opinion of the biocompatibility of these bone fixations, some patients experience symptoms of chronic inflammation around titanium implants even many years after their application. The aim of this study was to examine the levels of cytokines, chemokines, and growth factors released from the maxilla and mandible periosteum surrounding titanium fixations 11 months after the implantation procedure. Methods: From the study group (n = 20) consisting of patients with maxillofacial defects who underwent bimaxillary osteotomy, fragments of the periosteum of the maxilla and mandible adjacent to the titanium miniplates and screws were taken during routine bone fixation removal procedures. From the control group subjects (n = 20), fragments of healthy maxillary and mandibular periosteum were taken prior to surgical treatment of dentofacial deformities. The examination of cytokines, chemokines, and growth factors levels released from the periosteum of jaws was performed using the Bio-Plex Pro Human Cytokine Screening Panel (48-Plex). Results: The study group was characterized by a significant increase in the concentration of most of the tested-for proinflammatory cytokines/chemokines/growth factors compared to the control group, with greater amounts of inflammatory factors released from the periosteum covering the titanium implants in the mandible than from the periosteal cells surrounding the titanium implants in the maxilla. Conclusions: Prolonged exposure to titanium miniplates and screws leads to a disturbance of immune homeostasis in the periosteal cells of the maxilla and mandible. The data obtained indicate the need to remove fixations after the bone fragments have healed. Full article
(This article belongs to the Special Issue State-of-the-Art Innovations in Oral and Maxillofacial Surgery)
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12 pages, 595 KiB  
Protocol
A Protocol for a Systematic Review on Septic Arthritis of the Temporomandibular Joint (SATMJ)
by Karolina Lubecka, Kacper Galant, Maciej Chęciński, Kamila Chęcińska, Filip Bliźniak, Agata Ciosek, Tomasz Gładysz, Katarzyna Cholewa-Kowalska, Dariusz Chlubek and Maciej Sikora
J. Clin. Med. 2025, 14(7), 2392; https://doi.org/10.3390/jcm14072392 - 31 Mar 2025
Viewed by 429
Abstract
Background/Objectives: Septic arthritis of the temporomandibular joint is an infectious disease with a rapid course and possible long-term complications. It is crucial to diagnose and implement treatment quickly and to know the potential causes of the occurrence of SATMJ. The planned systematic review [...] Read more.
Background/Objectives: Septic arthritis of the temporomandibular joint is an infectious disease with a rapid course and possible long-term complications. It is crucial to diagnose and implement treatment quickly and to know the potential causes of the occurrence of SATMJ. The planned systematic review aims to summarize current knowledge on this subject. Methods: This protocol follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and checklist. The following scientific databases will be searched: ACM, BASE, ClinicalTrials.gov, Cochrane Library, Google Scholar, PubMed, and Scopus. Studies on SATMJ that are consistent with the pre-established PICOTS criteria will be included in the systematic review. Two authors will independently conduct the record screening, data extraction, and quality appraisal phases. The quality of the studies will be evaluated using the JBI critical appraisal tools. Certainty assessment will be conducted using the GRADE tool. The obtained research results and data will be used to define and establish the current scientific position on the diagnosis and treatment of SATMJ. Conclusions on the lack of association of gender, age, and race with the occurrence of this disease entity will be verified, among others. The planned systematic review will be based on extensive searches for studies with no high risk of bias. The aim is to assist clinicians in managing SATMJ, and to inspire future research. Full article
(This article belongs to the Special Issue State-of-the-Art Innovations in Oral and Maxillofacial Surgery)
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13 pages, 911 KiB  
Systematic Review
Overview of Systematic Reviews on Septic Arthritis of the Temporomandibular Joint (SATMJ)
by Karolina Lubecka, Kacper Galant, Maciej Chęciński, Kamila Chęcińska, Filip Bliźniak, Agata Ciosek, Tomasz Gładysz, Katarzyna Cholewa-Kowalska, Dariusz Chlubek and Maciej Sikora
J. Clin. Med. 2025, 14(3), 835; https://doi.org/10.3390/jcm14030835 - 27 Jan 2025
Viewed by 942
Abstract
Objectives: This overview of systematic reviews was carried out following the PRIOR guidelines. It aimed to collect and compare the results of systematic reviews on the etiology, diagnosis, and treatment standards of septic arthritis of the temporomandibular joint. Methods: ACM, BASE, [...] Read more.
Objectives: This overview of systematic reviews was carried out following the PRIOR guidelines. It aimed to collect and compare the results of systematic reviews on the etiology, diagnosis, and treatment standards of septic arthritis of the temporomandibular joint. Methods: ACM, BASE, Google Scholar, PubMed, and Scopus were searched on 5 January 2025, for systematic reviews on SATMJ etiology and treatment. Records underwent selection, AMSTAR 2 evaluation, data extraction, and qualitative synthesis. Results: Three systematic reviews were included, covering 38 reports (93 cases), 37 reports (91 cases), and 25 reports (40 cases), respectively. There are seven source reports common to all three reviews. The reviews co-indicate possible odontogenic etiology, differ in opinions about the impact of chronic diseases, and agree on the superiority of pharmacotherapy, though without consensus on specific antibiotics. Severe complications of SATMJ, including potentially lethal ones, were reported. Conclusions: SATMJ is a serious condition requiring urgent and precise medical intervention, yet no clear management guidelines exist. The low overlap and inconsistency of the previous systematic reviews provide a foundation for a more comprehensive synthesis. Full article
(This article belongs to the Special Issue State-of-the-Art Innovations in Oral and Maxillofacial Surgery)
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