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New Clinical Advances in Pediatric Asthma

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Pediatrics".

Deadline for manuscript submissions: 15 June 2026 | Viewed by 862

Special Issue Editor


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Guest Editor
1. Medical Faculty, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
2. Prima Nova, Zagreb, Croatia
Interests: allergy; pulmonology; lung function; clinical trials; occupational health; sports medicine
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Special Issue Information

Dear Colleagues,

Pediatric asthma still represents a major clinical challenge in the modern medical landscape despite major research discoveries. Although inhaled steroids have been shown to be the cornerstone in clinical management, being both efficacious and safe, there is still a lot of controversy about their use in both parents and physicians. Still significant problems exist regarding diagnosis, proper choice of therapy regarding different phenotypes, the place of specific allergen immunotherapy, pulmonary rehabilitation, and biologics as the new classes of treatment in moderate to severe pediatric asthma. Low level of control, impaired lung function, and low level of physical activity all present in a significant proportion of patients with pediatric asthma can have a long-lasting impact on health in adulthood and be precursors of COPD. The most common therapeutic strategies are based on inhaled steroids, β2-agonists, muscarinic antagonists, and oral anti-leukotrienes. For the last few years, they have also been based on innovative and highly effective biological therapies with monoclonal antibodies (i.e., anti-IgE, anti-IL4Rα/IL13Rα1, Anti-IL5/IL5Rα). However, many issues are still open, and there is a need for improvement in clinical management in pediatric asthma.

The present special edition aims to describe the most up-to-date clinical advances in pediatric asthma and to outline the most promising and challenging research perspectives for the future.

Prof. Dr. Davor Plavec
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric asthma
  • clinical management
  • treatment advances
  • diagnostic advances
  • biologic therapy
  • inhaled steroids
  • control of asthma
  • exacerbation prevention
  • quality of life

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Published Papers (1 paper)

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Review

13 pages, 540 KB  
Review
The Role of IOS in Identification of Specific Treatable Traits in Pediatric Asthma: Current Limitations and Future Perspectives—Narrative Review
by Joanna Połomska, Hanna Sikorska-Szaflik and Barbara Sozańska
J. Clin. Med. 2025, 14(20), 7368; https://doi.org/10.3390/jcm14207368 - 18 Oct 2025
Viewed by 561
Abstract
Asthma management in children aims to prevent ongoing symptoms, preserve lung function and support normal daily activities. Impulse oscillometry (IOS) represents a modern approach to evaluating lung function that is also suitable for performing in the pediatric asthma population. Further research is warranted [...] Read more.
Asthma management in children aims to prevent ongoing symptoms, preserve lung function and support normal daily activities. Impulse oscillometry (IOS) represents a modern approach to evaluating lung function that is also suitable for performing in the pediatric asthma population. Further research is warranted to clarify the role of IOS in the early identification of small airway disease (SAD) as a potential treatable asthma trait and to understand its implications for personalized treatment strategies. Before the integration of IOS into routine clinical protocols, it is necessary to establish population-specific reference values. Further studies in the pediatric population are needed to evaluate the added value of IOS in combination with conventional spirometry and fractional exhaled nitric oxide (FeNO). Future pediatric asthma management guidelines may consider incorporating the assessment of SAD with IOS as a possible tool for its evaluation. Full article
(This article belongs to the Special Issue New Clinical Advances in Pediatric Asthma)
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