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Journal of Clinical Medicine, Volume 14, Issue 24

December-2 2025 - 32 articles

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Articles (30)

  • Article
  • Open Access

Comparison of Oral Antidiabetic Medications and Insulin Therapy for Glucocorticoid-Induced Hyperglycemia in Patients with Autoimmune Diseases

  • Shinichiro Ueno,
  • Masataka Tajima,
  • Kiyomi Saito,
  • Masayuki Yoshikawa,
  • Takeo Isozaki,
  • Hitoshi Sato and
  • Erika Sugiyama
J. Clin. Med.2025, 14(24), 8642;https://doi.org/10.3390/jcm14248642 
(registering DOI)

5 December 2025

Background: Glucocorticoid-induced hyperglycemia (GCIH) is a common adverse effect of glucocorticoid (GC) therapy. Although evidence on oral antidiabetic medications (OADMs) for GCIH is emerging, direct comparisons with insulin therapy remain limited...

  • Review
  • Open Access

Technical Principles in Elective Surgical Treatment of Left Colon Diverticular Disease: A Scoping Review

  • Luca Emanuele Amodio,
  • Gianluca Rizzo,
  • Federica Marzi,
  • Camilla Marandola,
  • Francesco Ferrara and
  • Vincenzo Tondolo
J. Clin. Med.2025, 14(24), 8645;https://doi.org/10.3390/jcm14248645 
(registering DOI)

5 December 2025

Left colon diverticular disease (LCDD) is prevalent in the aging populations of industrialized countries, with many patients requiring surgery. Elective surgery decisions should consider individual health conditions and quality of life. Typically, su...

  • Case Report
  • Open Access
J. Clin. Med.2025, 14(24), 8637;https://doi.org/10.3390/jcm14248637 
(registering DOI)

5 December 2025

Hydroxyurea (HU) is a cytostatic drug used in oncotherapy. The drug has inhibitory effects on bone marrow and epithelial cells and causes minor side effects in the skin, including nail deformity, alopecia, and hyperpigmentation, and severe side effec...

  • Article
  • Open Access

Bariatric Surgery Impacts Retinal Vessel Status Assessed by Optical Coherence Tomography Angiography: A Prospective 12 Months Study

  • Xavier Carreras-Castañer,
  • Sofía Batlle-Ferrando,
  • Rubén Martín-Pinardel,
  • Teresa Hernández,
  • Cristian Oliva,
  • Irene Vila,
  • Rafael Castro-Dominguez,
  • Andrea Mendez-Mourelle,
  • Alfredo Adán and
  • Diana Tundidor
  • + 4 authors
J. Clin. Med.2025, 14(24), 8644;https://doi.org/10.3390/jcm14248644 
(registering DOI)

5 December 2025

Objectives: To assess retinal microvascular changes in patients with Grade II and III obesity before and after bariatric surgery using Optical Coherence Tomography Angiography (OCTA), and to compare these metrics with age- and sex-matched healthy con...

  • Article
  • Open Access

Vietnamese Consensus on the Structure and Content of Asthma Action Plan

  • Quan Vu Tran Thien,
  • Tho Nguyen Van,
  • Quyen Thi Le Pham,
  • Linh Duong Thi Chuc,
  • Cong Nguyen Hai,
  • Tuan Tran Trong Anh,
  • Khai Ho Quoc,
  • Huong Hoang Thi Lan and
  • Lan Le Thi Tuyet
J. Clin. Med.2025, 14(24), 8640;https://doi.org/10.3390/jcm14248640 
(registering DOI)

5 December 2025

Background/Objectives: Asthma action plans (AAPs) are recommended for patients’ self-management of asthma and should be adapted to a country’s situation. This study aimed to develop expert consensus on the optimal structure, content, and...

  • Article
  • Open Access
J. Clin. Med.2025, 14(24), 8643;https://doi.org/10.3390/jcm14248643 
(registering DOI)

5 December 2025

Background: Pediatric hypertension is an increasingly recognized health concern and is commonly influenced by modifiable factors such as dietary sodium intake and obesity and non-modifiable factors like family history of hypertension. Urinary sodium...

  • Case Report
  • Open Access
J. Clin. Med.2025, 14(24), 8641;https://doi.org/10.3390/jcm14248641 
(registering DOI)

5 December 2025

We describe a patient with post-essential thrombocythaemia myelofibrosis treated with intermittent hydroxyurea (Hu) therapy (20 mg/Kg, given as a single dose, thrice weekly), achieving sustained disease control and regression of bone marrow fibrosis....

  • Systematic Review
  • Open Access
J. Clin. Med.2025, 14(24), 8639;https://doi.org/10.3390/jcm14248639 
(registering DOI)

5 December 2025

Background/Objectives: Vertical ridge augmentation (VRA) is often necessary in severe bone atrophy, yet the most predictable approach remains unclear. This systematic review compared Guided Bone Regeneration (GBR) and the Shell Technique (ST) for ver...

  • Article
  • Open Access

Comparison of Shoulder and Elbow Biomechanical Characteristics in Left- and Right-Handed Youth Baseball Players

  • Hitoshi Shitara,
  • Tsuyoshi Tajika,
  • Tsuyoshi Ichinose,
  • Tsuyoshi Sasaki,
  • Noritaka Hamano,
  • Masataka Kamiyama,
  • Ryosuke Miyamoto,
  • Kurumi Nakase,
  • Fukuhisa Ino and
  • Takuma Kachi
  • + 5 authors
J. Clin. Med.2025, 14(24), 8638;https://doi.org/10.3390/jcm14248638 
(registering DOI)

5 December 2025

Background/Objectives: This study investigated biomechanical differences between right-handed (RHPs) and left-handed (LHPs) youth baseball players by analyzing shoulder and elbow range of motion (ROM), muscle strength, and humeral torsion. Side-to-si...

  • Article
  • Open Access

Combined Histological and Proteomic Analysis Reveals Muscle Denervation in KMT5B-Related Neurodevelopmental Disorder: A Case Report

  • Ozge Aksel Kilicarslan,
  • Andrea Gangfuß,
  • Heike Kölbel,
  • David Muhmann,
  • Kiran Polavarapu,
  • Rachel Thompson,
  • Linda-Isabell Schmitt,
  • Lola Lessard,
  • Lei Chen and
  • Astrid Eisenkölbl
  • + 4 authors
J. Clin. Med.2025, 14(24), 8636;https://doi.org/10.3390/jcm14248636 
(registering DOI)

5 December 2025

Background: Patients with neurodevelopmental and neuromuscular disorders often show overlapping clinical phenotypes. Pathogenic variants in KMT5B, a histone lysine methyltransferase, have been linked to neurodevelopmental disorders, yet their effects...

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J. Clin. Med. - ISSN 2077-0383