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  • Review
  • Open Access
160 Citations
50,690 Views
22 Pages

Colorectal Cancer: Epidemiology, Risk Factors, and Prevention

  • Gholamreza Roshandel,
  • Fatemeh Ghasemi-Kebria and
  • Reza Malekzadeh

17 April 2024

Colorectal cancer (CRC) is the third most common cancer and the second most common cause of cancer mortality worldwide. There are disparities in the epidemiology of CRC across different populations, most probably due to differences in exposure to lif...

  • Article
  • Open Access
3 Citations
44,954 Views
18 Pages

Repeated COVID-19 Vaccination as a Poor Prognostic Factor in Pancreatic Cancer: A Retrospective, Single-Center Cohort Study

  • Makoto Abue,
  • Mai Mochizuki,
  • Rie Shibuya-Takahashi,
  • Kensuke Ota,
  • Yuta Wakui,
  • Wataru Iwai,
  • Jun Kusaka,
  • Masashi Saito,
  • Shinichi Suzuki and
  • Ikuro Sato
  • + 1 author

16 June 2025

Background/Objectives: The COVID-19 vaccine is a significant technological advancement with widespread global use. However, its effect on cancer immunity, particularly with repeated vaccinations, remains unclear. We aimed to investigate the relations...

  • Review
  • Open Access
34 Citations
35,584 Views
36 Pages

Diagnosis, Prognosis, and Treatment of Canine Hemangiosarcoma: A Review Based on a Consensus Organized by the Brazilian Association of Veterinary Oncology, ABROVET

  • Andrigo Barboza De Nardi,
  • Cristina de Oliveira Massoco Salles Gomes,
  • Carlos Eduardo Fonseca-Alves,
  • Felipe Noleto de Paiva,
  • Laís Calazans Menescal Linhares,
  • Gabriel João Unger Carra,
  • Rodrigo dos Santos Horta,
  • Felipe Augusto Ruiz Sueiro,
  • Paulo Cesar Jark and
  • Adriana Tomoko Nishiya
  • + 24 authors

29 March 2023

Hemangiosarcoma is a mesenchymal neoplasm originating in the endothelial cells of blood vessels; they can be classified as non-visceral and visceral types. Non-visceral hemangiosarcomas can affect the skin, subcutaneous tissues, and muscle tissues; v...

  • Review
  • Open Access
247 Citations
34,316 Views
35 Pages

Mechanisms of ADC Toxicity and Strategies to Increase ADC Tolerability

  • Toan D. Nguyen,
  • Brandon M. Bordeau and
  • Joseph P. Balthasar

24 January 2023

Anti-cancer antibody-drug conjugates (ADCs) aim to expand the therapeutic index of traditional chemotherapy by employing the targeting specificity of monoclonal antibodies (mAbs) to increase the efficiency of the delivery of potent cytotoxic agents t...

  • Review
  • Open Access
426 Citations
32,203 Views
21 Pages

Obesity and Cancer: A Current Overview of Epidemiology, Pathogenesis, Outcomes, and Management

  • Sukanya Pati,
  • Wadeed Irfan,
  • Ahmad Jameel,
  • Shahid Ahmed and
  • Rabia K. Shahid

12 January 2023

Background: Obesity or excess body fat is a major global health challenge that has not only been associated with diabetes mellitus and cardiovascular disease but is also a major risk factor for the development of and mortality related to a subgroup o...

  • Review
  • Open Access
59 Citations
30,543 Views
55 Pages

Microplastics in the Human Body: Exposure, Detection, and Risk of Carcinogenesis: A State-of-the-Art Review

  • Eliasz Dzierżyński,
  • Piotr J. Gawlik,
  • Damian Puźniak,
  • Wojciech Flieger,
  • Katarzyna Jóźwik,
  • Grzegorz Teresiński,
  • Alicja Forma,
  • Paulina Wdowiak,
  • Jacek Baj and
  • Jolanta Flieger

1 November 2024

Background: Humans cannot avoid plastic exposure due to its ubiquitous presence in the natural environment. The waste generated is poorly biodegradable and exists in the form of MPs, which can enter the human body primarily through the digestive trac...

  • Review
  • Open Access
35 Citations
28,188 Views
13 Pages

Autoimmune Atrophic Gastritis: A Clinical Review

  • Chiara Castellana,
  • Leonardo Henry Eusebi,
  • Elton Dajti,
  • Veronica Iascone,
  • Amanda Vestito,
  • Pietro Fusaroli,
  • Lorenzo Fuccio,
  • Antonietta D’Errico and
  • Rocco Maurizio Zagari

28 March 2024

Autoimmune atrophic gastritis (AAG) is a chronic condition characterized by the presence of atrophy in the oxyntic mucosa due to anti-parietal cell antibodies. This review provides a comprehensive and up-to-date overview of autoimmune atrophic gastri...

  • Article
  • Open Access
6 Citations
28,095 Views
13 Pages

Methylene Blue Metabolic Therapy Restrains In Vivo Ovarian Tumor Growth

  • Jorgelindo da Veiga Moreira,
  • Nancy Nleme,
  • Laurent Schwartz,
  • Kim Leclerc-Desaulniers,
  • Euridice Carmona,
  • Anne-Marie Mes-Masson and
  • Mario Jolicoeur

13 January 2024

Ovarian cancer remains a significant challenge, especially in platinum-resistant cases where treatment options are limited. In this study, we investigated the potential of methylene blue (MB) as a metabolic therapy and complementary treatment approac...

  • Review
  • Open Access
52 Citations
28,070 Views
32 Pages

Vaping, Environmental Toxicants Exposure, and Lung Cancer Risk

  • Shaimaa A. Shehata,
  • Eman A. Toraih,
  • Ezzat A. Ismail,
  • Abeer M. Hagras,
  • Ekramy Elmorsy and
  • Manal S. Fawzy

12 September 2023

Lung cancer (LC) is the second-most prevalent tumor worldwide. According to the most recent GLOBOCAN data, over 2.2 million LC cases were reported in 2020, with an estimated new death incident of 1,796,144 lung cancer cases. Genetic, lifestyle, and e...

  • Review
  • Open Access
96 Citations
27,044 Views
53 Pages

What Is Known about Breast Cancer in Young Women?

  • Jie Wei Zhu,
  • Parsa Charkhchi,
  • Shadia Adekunte and
  • Mohammad R. Akbari

22 March 2023

Breast cancer (BC) is the second leading cause of cancer-related death in women under the age of 40 years worldwide. In addition, the incidence of breast cancer in young women (BCYW) has been rising. Young women are not the focus of screening program...

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Cancers - ISSN 2072-6694