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Most Cited

  • Review
  • Open Access
401 Citations
30,385 Views
21 Pages

Obesity and Cancer: A Current Overview of Epidemiology, Pathogenesis, Outcomes, and Management

  • Sukanya Pati,
  • Wadeed Irfan,
  • Ahmad Jameel,
  • Shahid Ahmed and
  • Rabia K. Shahid

12 January 2023

Background: Obesity or excess body fat is a major global health challenge that has not only been associated with diabetes mellitus and cardiovascular disease but is also a major risk factor for the development of and mortality related to a subgroup o...

  • Article
  • Open Access
261 Citations
16,710 Views
29 Pages

Brain Tumor Detection Based on Deep Learning Approaches and Magnetic Resonance Imaging

  • Akmalbek Bobomirzaevich Abdusalomov,
  • Mukhriddin Mukhiddinov and
  • Taeg Keun Whangbo

18 August 2023

The rapid development of abnormal brain cells that characterizes a brain tumor is a major health risk for adults since it can cause severe impairment of organ function and even death. These tumors come in a wide variety of sizes, textures, and locati...

  • Systematic Review
  • Open Access
227 Citations
20,622 Views
39 Pages

Update on Prevalence of Pain in Patients with Cancer 2022: A Systematic Literature Review and Meta-Analysis

  • Rolf A. H. Snijders,
  • Linda Brom,
  • Maurice Theunissen and
  • Marieke H. J. van den Beuken-van Everdingen

18 January 2023

Experiencing pain and insufficient relief can be devastating and negatively affect a patient’s quality of life. Developments in oncology such as new treatments and adjusted pain management guidelines may have influenced the prevalence of cancer pain...

  • Review
  • Open Access
218 Citations
31,678 Views
35 Pages

Mechanisms of ADC Toxicity and Strategies to Increase ADC Tolerability

  • Toan D. Nguyen,
  • Brandon M. Bordeau and
  • Joseph P. Balthasar

24 January 2023

Anti-cancer antibody-drug conjugates (ADCs) aim to expand the therapeutic index of traditional chemotherapy by employing the targeting specificity of monoclonal antibodies (mAbs) to increase the efficiency of the delivery of potent cytotoxic agents t...

  • Review
  • Open Access
186 Citations
14,447 Views
23 Pages

Natural Products/Bioactive Compounds as a Source of Anticancer Drugs

  • Syeda Tasmia Asma,
  • Ulas Acaroz,
  • Kálmán Imre,
  • Adriana Morar,
  • Syed Rizwan Ali Shah,
  • Syed Zajif Hussain,
  • Damla Arslan-Acaroz,
  • Hayri Demirbas,
  • Zehra Hajrulai-Musliu and
  • Fatih Ramazan Istanbullugil
  • + 7 authors

15 December 2022

Cancer is one of the major deadly diseases globally. The alarming rise in the mortality rate due to this disease attracks attention towards discovering potent anticancer agents to overcome its mortality rate. The discovery of novel and effective anti...

  • Review
  • Open Access
168 Citations
13,743 Views
15 Pages

The Current Status of Photodynamic Therapy in Cancer Treatment

  • Wenqi Jiang,
  • Mingkang Liang,
  • Qifang Lei,
  • Guangzhi Li and
  • Song Wu

18 January 2023

Although we have made great strides in treating deadly diseases over the years, cancer therapy still remains a daunting challenge. Among numerous anticancer methods, photodynamic therapy (PDT), a non-invasive therapeutic approach, has attracted much...

  • Review
  • Open Access
166 Citations
17,499 Views
29 Pages

Current Status and Future Prospects for Esophageal Cancer

  • Mahdi Sheikh,
  • Gholamreza Roshandel,
  • Valerie McCormack and
  • Reza Malekzadeh

26 January 2023

Esophageal cancer (EC) is the ninth most common cancer and the sixth leading cause of cancer deaths worldwide. Esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC) are the two main histological subtypes with distinct epidemio...

  • Review
  • Open Access
166 Citations
19,639 Views
20 Pages

CAR-T: What Is Next?

  • Yi-Ju Chen,
  • Bams Abila and
  • Yasser Mostafa Kamel

21 January 2023

The year 2017 was marked by the Food and Drug Administration (FDA) approval of the first two chimeric antigen receptor-T (CAR-T) therapies. The approved indications were for the treatment of relapsed or refractory diffuse large B-cell lymphoma (DLBCL...

  • Review
  • Open Access
163 Citations
23,368 Views
72 Pages

Deep Learning for Medical Image-Based Cancer Diagnosis

  • Xiaoyan Jiang,
  • Zuojin Hu,
  • Shuihua Wang and
  • Yudong Zhang

13 July 2023

(1) Background: The application of deep learning technology to realize cancer diagnosis based on medical images is one of the research hotspots in the field of artificial intelligence and computer vision. Due to the rapid development of deep learning...

  • Review
  • Open Access
162 Citations
14,002 Views
35 Pages

28 July 2023

The genomics-based concept of precision medicine began to emerge following the completion of the Human Genome Project. In contrast to evidence-based medicine, precision medicine will allow doctors and scientists to tailor the treatment of different s...

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Cancers - ISSN 2072-6694Creative Common CC BY license