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  • Systematic Review
  • Open Access
15 Citations
25,133 Views
14 Pages

Networks in Healthcare: A Systematic Review

  • Santhosh Kumar Rajamani and
  • Radha Srinivasan Iyer

Networks form the backbone of any healthcare system. Various databases were searched with relevant keywords, data were abstracted, and numerous papers were appraised for this synthesis. This compiled systematic review gives a comprehensive overview o...

  • Review
  • Open Access
15 Citations
24,575 Views
40 Pages

Generative Artificial Intelligence in Healthcare: Applications, Implementation Challenges, and Future Directions

  • Syed Arman Rabbani,
  • Mohamed El-Tanani,
  • Shrestha Sharma,
  • Syed Salman Rabbani,
  • Yahia El-Tanani,
  • Rakesh Kumar and
  • Manita Saini

Generative artificial intelligence (AI) is rapidly transforming healthcare systems since the advent of OpenAI in 2022. It encompasses a class of machine learning techniques designed to create new content and is classified into large language models (...

  • Review
  • Open Access
60 Citations
24,210 Views
47 Pages

Recent Advances in Large Language Models for Healthcare

  • Khalid Nassiri and
  • Moulay A. Akhloufi

Recent advances in the field of large language models (LLMs) underline their high potential for applications in a variety of sectors. Their use in healthcare, in particular, holds out promising prospects for improving medical practices. As we highlig...

  • Review
  • Open Access
72 Citations
20,372 Views
33 Pages

Genomics for Emerging Pathogen Identification and Monitoring: Prospects and Obstacles

  • Vishakha Vashisht,
  • Ashutosh Vashisht,
  • Ashis K. Mondal,
  • Jaspreet Farmaha,
  • Ahmet Alptekin,
  • Harmanpreet Singh,
  • Pankaj Ahluwalia,
  • Anaka Srinivas and
  • Ravindra Kolhe

Emerging infectious diseases (EIDs) pose an increasingly significant global burden, driven by urbanization, population explosion, global travel, changes in human behavior, and inadequate public health systems. The recent SARS-CoV-2 pandemic highlight...

  • Review
  • Open Access
82 Citations
20,245 Views
49 Pages

Deep learning has emerged as a powerful tool for medical image analysis and diagnosis, demonstrating high performance on tasks such as cancer detection. This literature review synthesizes current research on deep learning techniques applied to lung c...

  • Review
  • Open Access
80 Citations
15,461 Views
22 Pages

Digital twins (DTs) are becoming increasingly popular in various industries, and their potential for healthcare in the metaverse continues to attract attention. The metaverse is a virtual world where individuals interact with digital replicas of them...

  • Review
  • Open Access
19 Citations
15,079 Views
64 Pages

Lung cancer is a leading cause of cancer-related deaths worldwide, emphasizing the significance of early detection. Computer-aided diagnostic systems have emerged as valuable tools for aiding radiologists in the analysis of medical images, particular...

  • Review
  • Open Access
17 Citations
13,676 Views
17 Pages

Artificial Intelligence in Wound Care: A Narrative Review of the Currently Available Mobile Apps for Automatic Ulcer Segmentation

  • Davide Griffa,
  • Alessio Natale,
  • Yuri Merli,
  • Michela Starace,
  • Nico Curti,
  • Martina Mussi,
  • Gastone Castellani,
  • Davide Melandri,
  • Bianca Maria Piraccini and
  • Corrado Zengarini

Introduction: Chronic ulcers significantly burden healthcare systems, requiring precise measurement and assessment for effective treatment. Traditional methods, such as manual segmentation, are time-consuming and error-prone. This review evaluates th...

  • Review
  • Open Access
8 Citations
12,078 Views
24 Pages

Digital Pathology: A Comprehensive Review of Open-Source Histological Segmentation Software

  • Anna Maria Pavone,
  • Antonino Giulio Giannone,
  • Daniela Cabibi,
  • Simona D’Aprile,
  • Simona Denaro,
  • Giuseppe Salvaggio,
  • Rosalba Parenti,
  • Anthony Yezzi and
  • Albert Comelli

In the era of digitalization, the biomedical sector has been affected by the spread of artificial intelligence. In recent years, the possibility of using deep and machine learning methods for clinical diagnostic and therapeutic interventions has been...

  • Review
  • Open Access
8 Citations
11,547 Views
24 Pages

Current Applications of Artificial Intelligence in the Neonatal Intensive Care Unit

  • Dimitrios Rallis,
  • Maria Baltogianni,
  • Konstantina Kapetaniou and
  • Vasileios Giapros

Artificial intelligence (AI) refers to computer algorithms that replicate the cognitive function of humans. Machine learning is widely applicable using structured and unstructured data, while deep learning is derived from the neural networks of the h...

  • Review
  • Open Access
9 Citations
11,494 Views
70 Pages

Advancements in Breast Cancer Detection: A Review of Global Trends, Risk Factors, Imaging Modalities, Machine Learning, and Deep Learning Approaches

  • Md. Atiqur Rahman,
  • M. Saddam Hossain Khan,
  • Yutaka Watanobe,
  • Jarin Tasnim Prioty,
  • Tasfia Tahsin Annita,
  • Samura Rahman,
  • Md. Shakil Hossain,
  • Saddit Ahmed Aitijjo,
  • Rafsun Islam Taskin and
  • Touhid Bhuiyan
  • + 2 authors

Breast cancer remains a critical global health challenge, with over 2.1 million new cases annually. This review systematically evaluates recent advancements (2022–2024) in machine and deep learning approaches for breast cancer detection and ris...

  • Systematic Review
  • Open Access
9 Citations
11,228 Views
27 Pages

With the increase in biosensors and data collection devices in the healthcare industry, artificial intelligence and machine learning have attracted much attention in recent years. In this study, we offered a comprehensive review of the current trends...

  • Article
  • Open Access
21 Citations
11,218 Views
12 Pages

Background: Currently, discriminating Iron Deficiency Anemia (IDA) from other anemia requires an expensive test (serum ferritin). Complete Blood Count (CBC) tests are less costly and more widely available. Machine learning models have not yet been ap...

  • Review
  • Open Access
57 Citations
10,876 Views
16 Pages

This review explores the transformative integration of artificial intelligence (AI) and healthcare through conversational AI leveraging Natural Language Processing (NLP). Focusing on Large Language Models (LLMs), this paper navigates through various...

  • Feature Paper
  • Article
  • Open Access
8 Citations
10,205 Views
10 Pages

Minimal Hip Joint Space Width Measured on X-rays by an Artificial Intelligence Algorithm—A Study of Reliability and Agreement

  • Anne Mathilde Andersen,
  • Benjamin S. B. Rasmussen,
  • Ole Graumann,
  • Søren Overgaard,
  • Michael Lundemann,
  • Martin Haagen Haubro,
  • Claus Varnum,
  • Janne Rasmussen and
  • Janni Jensen

Minimal joint space width (mJSW) is a radiographic measurement used in the diagnosis of hip osteoarthritis. A large variance when measuring mJSW highlights the need for a supporting diagnostic tool. This study aimed to estimate the reliability of a d...

  • Review
  • Open Access
33 Citations
10,169 Views
14 Pages

Recent advancements in artificial intelligence (AI) have facilitated its widespread adoption in primary medical services, addressing the demand–supply imbalance in healthcare. Vision Transformers (ViT) have emerged as state-of-the-art computer...

  • Article
  • Open Access
21 Citations
10,002 Views
16 Pages

Breast cancer is among the most common cancers found in women, causing cancer-related deaths and making it a severe public health issue. Early prediction of breast cancer can increase the chances of survival and promote early medical treatment. Moreo...

  • Article
  • Open Access
8 Citations
9,555 Views
12 Pages

A Comprehensive Analysis of Trapezius Muscle EMG Activity in Relation to Stress and Meditation

  • Mohammad Ahmed,
  • Michael Grillo,
  • Amirtaha Taebi,
  • Mehmet Kaya and
  • Peshala Thibbotuwawa Gamage

Introduction: This study analyzes the efficacy of trapezius muscle electromyography (EMG) in discerning mental states, namely stress and meditation. Methods: Fifteen healthy participants were monitored to assess their physiological responses to menta...

  • Article
  • Open Access
5 Citations
9,499 Views
16 Pages

An interesting issue observed in some drugs is the “double peak phenomenon” (DPP). In DPP, the concentration-time (C-t) profile does not follow the usual shape but climbs to a peak and then begins to degrade before rising again to a secon...

  • Article
  • Open Access
35 Citations
9,454 Views
26 Pages

Supporting the Demand on Mental Health Services with AI-Based Conversational Large Language Models (LLMs)

  • Tin Lai,
  • Yukun Shi,
  • Zicong Du,
  • Jiajie Wu,
  • Ken Fu,
  • Yichao Dou and
  • Ziqi Wang

The demand for psychological counselling has grown significantly in recent years, particularly with the global outbreak of COVID-19, which heightened the need for timely and professional mental health support. Online psychological counselling emerged...

  • Communication
  • Open Access
32 Citations
9,406 Views
21 Pages

The Crucial Role of Interdisciplinary Conferences in Advancing Explainable AI in Healthcare

  • Ankush U. Patel,
  • Qiangqiang Gu,
  • Ronda Esper,
  • Danielle Maeser and
  • Nicole Maeser

As artificial intelligence (AI) integrates within the intersecting domains of healthcare and computational biology, developing interpretable models tailored to medical contexts is met with significant challenges. Explainable AI (XAI) is vital for fos...

  • Review
  • Open Access
1 Citations
9,201 Views
15 Pages

Radiation-induced gastrointestinal (GI) dose constraints are still a matter of concern with the ongoing evolution of patient outcomes and treatment-related toxicity in the era of image-guided intensity-modulated radiation therapy (IMRT), stereotactic...

  • Article
  • Open Access
9 Citations
9,090 Views
15 Pages

The three-dimensional protein structure is pivotal in comprehending biological phenomena. It directly governs protein function and hence aids in drug discovery. The development of protein prediction algorithms, such as AlphaFold2, ESMFold, and trRose...

  • Review
  • Open Access
13 Citations
9,070 Views
26 Pages

Background: Over the past few years, clinical studies have utilized machine learning in telehealth and smart care for disease management, self-management, and managing health issues like pulmonary diseases, heart failure, diabetes screening, and intr...

  • Review
  • Open Access
18 Citations
8,874 Views
26 Pages

Artificial Intelligence (AI) and deep learning models have revolutionized diagnosis, prognostication, and treatment planning by extracting complex patterns from medical images, enabling more accurate, personalized, and timely clinical decisions. Desp...

  • Article
  • Open Access
18 Citations
8,542 Views
25 Pages

Survey of Multimodal Medical Question Answering

  • Hilmi Demirhan and
  • Wlodek Zadrozny

Multimodal medical question answering (MMQA) is a vital area bridging healthcare and Artificial Intelligence (AI). This survey methodically examines the MMQA research published in recent years. We collect academic literature through Google Scholar, a...

  • Perspective
  • Open Access
13 Citations
8,272 Views
13 Pages

AlphaFold2 Update and Perspectives

  • Sébastien Tourlet,
  • Ragousandirane Radjasandirane,
  • Julien Diharce and
  • Alexandre G. de Brevern

Access to the three-dimensional (3D) structural information of macromolecules is of major interest in both fundamental and applied research. Obtaining this experimental data can be complex, time consuming, and costly. Therefore, in silico computation...

  • Review
  • Open Access
14 Citations
8,267 Views
17 Pages

This review explores the integration of artificial intelligence (AI) and machine learning (ML) into kidney transplantation (KT), set against the backdrop of a significant donor organ shortage and the evolution of ‘Next-Generation Healthcare&rsq...

  • Article
  • Open Access
12 Citations
8,228 Views
26 Pages

Synthetic MRI Generation from CT Scans for Stroke Patients

  • Jake McNaughton,
  • Samantha Holdsworth,
  • Benjamin Chong,
  • Justin Fernandez,
  • Vickie Shim and
  • Alan Wang

CT scans are currently the most common imaging modality used for suspected stroke patients due to their short acquisition time and wide availability. However, MRI offers superior tissue contrast and image quality. In this study, eight deep learning m...

  • Article
  • Open Access
8 Citations
8,050 Views
9 Pages

An IoT-Based Automatic and Continuous Urine Measurement System

  • Alexander Lee,
  • Melissa Lee and
  • Hsi-Jen James Yeh

Urine output is an important indicator of renal function. In hospitals, urine is collected using a catheter connected to a urine collection bag that has volume gradation markings. This type of visual measurement has low levels of accuracy and is labo...

  • Article
  • Open Access
7 Citations
7,971 Views
21 Pages

Background: Epilepsy is one of the most common and devastating neurological disorders, manifesting with seizures and affecting approximately 1–2% of the world’s population. The criticality of seizure occurrence and associated risks, combi...

  • Article
  • Open Access
21 Citations
7,958 Views
15 Pages

Real-Time Jaundice Detection in Neonates Based on Machine Learning Models

  • Ahmad Yaseen Abdulrazzak,
  • Saleem Latif Mohammed,
  • Ali Al-Naji and
  • Javaan Chahl

Introduction: Despite the many attempts made by researchers to diagnose jaundice non-invasively using machine learning techniques, the low amount of data used to build their models remains the key factor limiting the performance of their models. Obje...

  • Article
  • Open Access
28 Citations
7,876 Views
19 Pages

The reduction of childhood mortality is an ongoing struggle and a commonly used factor in determining progress in the medical field. The under-5 mortality number is around 5 million around the world, with many of the deaths being preventable. In ligh...

  • Review
  • Open Access
29 Citations
7,791 Views
16 Pages

This article delves into the intersection of generative AI and digital twins within drug discovery, exploring their synergistic potential to revolutionize pharmaceutical research and development. Through various instances and examples, we illuminate...

  • Article
  • Open Access
49 Citations
7,766 Views
21 Pages

Enhancing Brain Tumor Classification with Transfer Learning across Multiple Classes: An In-Depth Analysis

  • Syed Ahmmed,
  • Prajoy Podder,
  • M. Rubaiyat Hossain Mondal,
  • S M Atikur Rahman,
  • Somasundar Kannan,
  • Md Junayed Hasan,
  • Ali Rohan and
  • Alexander E. Prosvirin

This study focuses on leveraging data-driven techniques to diagnose brain tumors through magnetic resonance imaging (MRI) images. Utilizing the rule of deep learning (DL), we introduce and fine-tune two robust frameworks, ResNet 50 and Inception V3,...

  • Article
  • Open Access
29 Citations
7,708 Views
14 Pages

A common consequence of diabetes mellitus called diabetic retinopathy (DR) results in lesions on the retina that impair vision. It can cause blindness if not detected in time. Unfortunately, DR cannot be reversed, and treatment simply keeps eyesight...

  • Review
  • Open Access
18 Citations
7,547 Views
12 Pages

Exploring the Role of ChatGPT in Oncology: Providing Information and Support for Cancer Patients

  • Maurizio Cè,
  • Vittoria Chiarpenello,
  • Alessandra Bubba,
  • Paolo Florent Felisaz,
  • Giancarlo Oliva,
  • Giovanni Irmici and
  • Michaela Cellina

Introduction: Oncological patients face numerous challenges throughout their cancer journey while navigating complex medical information. The advent of AI-based conversational models like ChatGPT (San Francisco, OpenAI) represents an innovation in on...

  • Article
  • Open Access
16 Citations
7,484 Views
13 Pages

Lip-Reading Advancements: A 3D Convolutional Neural Network/Long Short-Term Memory Fusion for Precise Word Recognition

  • Themis Exarchos,
  • Georgios N. Dimitrakopoulos,
  • Aristidis G. Vrahatis,
  • Georgios Chrysovitsiotis,
  • Zoi Zachou and
  • Efthymios Kyrodimos

Lip reading, the art of deciphering spoken words from the visual cues of lip movements, has garnered significant interest for its potential applications in diverse fields, including assistive technologies, human–computer interaction, and securi...

  • Data Descriptor
  • Open Access
9 Citations
7,478 Views
10 Pages

NJN: A Dataset for the Normal and Jaundiced Newborns

  • Ahmad Yaseen Abdulrazzak,
  • Saleem Latif Mohammed and
  • Ali Al-Naji

Neonatal jaundice is a prevalent condition among newborns, with potentially severe complications that can result in permanent brain damage if left untreated during its early stages. The existing approaches for jaundice detection involve invasive proc...

  • Review
  • Open Access
2 Citations
7,460 Views
14 Pages

Artificial Intelligence as Assessment Tool in Occupational Therapy: A Scoping Review

  • Christos Kokkotis,
  • Ioannis Kansizoglou,
  • Theodoros Stampoulis,
  • Erasmia Giannakou,
  • Panagiotis Siaperas,
  • Stavros Kallidis,
  • Maria Koutra,
  • Christina Koutra,
  • Anastasia Beneka and
  • Evangelos Bebetsos

Occupational therapy (OT) is vital in improving functional outcomes and aiding recovery for individuals with long-term disabilities, particularly those resulting from neurological diseases. Traditional assessment methods often rely on clinical judgme...

  • Article
  • Open Access
9 Citations
7,356 Views
42 Pages

Human immunoglobulin allotypes are allelic antigenic determinants (or “markers”) determined serologically, classically by hemagglutination inhibition, on the human immunoglobulin (IG) or antibody heavy and light chains. The allotypes have...

  • Article
  • Open Access
4 Citations
6,858 Views
16 Pages

An Open-Access Dataset of Hospitalized Cardiac-Arrest Patients: Machine-Learning-Based Predictions Using Clinical Documentation

  • Lahiru Theekshana Weerasinghe Rajapaksha,
  • Sugandima Mihirani Vidanagamachchi,
  • Sampath Gunawardena and
  • Vajira Thambawita

Cardiac arrest is a sudden loss of heart function with serious consequences. In developing countries, healthcare professionals use clinical documentation to track patient information. These data are used to predict the development of cardiac arrest....

  • Article
  • Open Access
9 Citations
6,586 Views
12 Pages

Background: Heart failure poses a significant global health challenge, with high rates of readmission and mortality. Accurate models to predict these outcomes are essential for effective patient management. This study investigates the impact of data...

  • Review
  • Open Access
5 Citations
6,525 Views
20 Pages

Systematic Review of Deep Learning Techniques in Skin Cancer Detection

  • Carolina Magalhaes,
  • Joaquim Mendes and
  • Ricardo Vardasca

Skin cancer is a serious health condition, as it can locally evolve into disfiguring states or metastasize to different tissues. Early detection of this disease is critical because it increases the effectiveness of treatment, which contributes to imp...

  • Article
  • Open Access
15 Citations
6,492 Views
17 Pages

Assessment of Voice Disorders Using Machine Learning and Vocal Analysis of Voice Samples Recorded through Smartphones

  • Michele Giuseppe Di Cesare,
  • David Perpetuini,
  • Daniela Cardone and
  • Arcangelo Merla

Background: The integration of edge computing into smart healthcare systems requires the development of computationally efficient models and methodologies for monitoring and detecting patients’ healthcare statuses. In this context, mobile devic...

  • Article
  • Open Access
8 Citations
6,448 Views
30 Pages

Background: In recent years, there has been increasing research in the applications of Artificial Intelligence in the medical industry. Digital pathology has seen great success in introducing the use of technology in the digitisation and analysis of...

  • Editorial
  • Open Access
13 Citations
6,438 Views
9 Pages

Biomedical informatics can be considered as a multidisciplinary research and educational field situated at the intersection of computational sciences (including computer science, data science, mathematics, and statistics), biology, and medicine. In r...

  • Article
  • Open Access
14 Citations
6,238 Views
36 Pages

Early Breast Cancer Detection Based on Deep Learning: An Ensemble Approach Applied to Mammograms

  • Youness Khourdifi,
  • Alae El Alami,
  • Mounia Zaydi,
  • Yassine Maleh and
  • Omar Er-Remyly

Background: Breast cancer is one of the leading causes of death in women, making early detection through mammography crucial for improving survival rates. However, human interpretation of mammograms is often prone to diagnostic errors. This study add...

  • Article
  • Open Access
9 Citations
6,225 Views
31 Pages

Background: Cognitive loss is one of the biggest health problems for older people. The incidence of dementia increases with age, so Alzheimer’s disease (AD), the most prevalent type of dementia, is expected to increase. Patients with dementia f...

  • Review
  • Open Access
6,155 Views
25 Pages

In vaccine development, many use the spike protein (S protein), which has multiple “spike-like” structures protruding from the spherical structure of the coronavirus, as an antigen. However, there are concerns about its effectiveness and...

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BioMedInformatics - ISSN 2673-7426