Special Issues

Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Developmental Origins of Health and Disease: Antioxidants as Strategy for Prevention and Treatment submission deadline 30 Nov 2025 | 4 articles | Viewed by 6003 | Submission Open
Keywords: oxidative stress; pregnancy; germline damage; obstetric complications; fetal programming
Glutathione and Health: From Development to Disease
edited by and Vasilis K. Vasiliou
submission deadline 30 Nov 2025 | 3 articles | Viewed by 4988 | Submission Open
Keywords: glutathione; antioxidants; antioxidant enzymes; oxidative stress; redox biology; molecular biology; cellular biology; biochemistry; development; disease
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Inflammation in Neurologic Diseases
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3796 | Submission Open
Keywords: oxidative stress; nitrosative stress; neuroinflammation; neurodegeneration; neuronal apoptosis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Antioxidants in Hypoxia and Human Pathophysiology Settings, 2nd Edition
edited by and Alejandro Gonzalez-Candia
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3753 | Submission Open
Keywords: tissue hypoxia; reperfusion injury; hypoxic preconditioning; oxidative stress; antioxidants; hypoxic programing; microRNA; clinical hypoxic settings
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Natural Antioxidants from Plant-Based By-Products: Mechanisms and Applications in Food Systems submission deadline 30 Nov 2025 | 4 articles | Viewed by 3197 | Submission Open
Keywords: natural antioxidants; plant-based by-products; phenolic compounds; food preservation; shelf life extension; sustainable food systems; extraction techniques
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Oxidative Stress in Cell Senescence
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2880 | Submission Open
Keywords: stem cells; cell senescence; regenerative medicine; antioxidant strategies; age-related diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Signaling in Cancer: Mechanisms and Therapeutic Opportunities
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2266 | Submission Open
Keywords: oxidative stress; cancer; reactive oxygen species (ROS); redox signaling; natural compounds; ferroptosis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Plant Stress and Plant Physiology
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 2224 | Submission Open
Keywords: ROS signaling; stress adaptive responses; halophyte vs glycophyte; redox homeostasis; molecular crosstalk with  ROS signaling; biotic; abiotic; soil borne; and air pollutants
(This special issue belongs to the Section ROS, RNS and RSS)
Inflammation and Oxidative Stress in Articular Cartilage submission deadline 30 Nov 2025 | 2 articles | Viewed by 1595 | Submission Open
Keywords: cartilage; chondrocyte; joint inflammation; arthritis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Hydrogen Sulfide, Reactive Sulfur Species, and Donor Compounds: Natural and Synthetic Tools for Physiology and Disease submission deadline 30 Nov 2025 | 1 articles | Viewed by 1280 | Submission Open
Keywords: hydrogen sulfide; H2S donors; H2S hybrid compounds; H2S sources; pharmacological tools; H2S signaling
Berry Antioxidants in Health and Disease—2nd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 715 | Submission Open
Keywords: berries; antioxidants; polyphenols; berry metabolites; oxidative stress; chronic diseases; cardiovascular disease; metabolic syndrome; diabetes mellitus; cancer; neurodegenerative disease; gut microbiome
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioactive Antioxidants: Structural Characterization, Synthetic Pathways, and Clinical Applications
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 624 | Submission Open
Keywords: bioactive antioxidants; therapeutic potential; synthetic strategies; structural characterization
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Oxidative Metabolism and Mitochondrial Dysfunction in Metabolic Diseases—3rd Edition submission deadline 30 Nov 2025 | Viewed by 255 | Submission Open
Keywords: mitochondria function; oxidative processes; metabolic diseases; reactive oxygen species; therapeutic approaches; mitochondrial integrity; energy production; mitochondrial bioenergetic; metabolism; mitochondrial dynamic
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Natural Products to Mitigate Oxidative Stress and Inflammation in Non-Communicable Intestinal Diseases submission deadline 30 Nov 2025 | Viewed by 210 | Submission Open
Keywords: natural bioactives; phytochemicals; oxidative stress; inflammation; non-communicable intestinal diseases; colorectal cancer; inflammatory bowel diseases; signalling pathways
Advances in Mitochondrial Redox Biology—Second Edition
edited by
submission deadline 30 Nov 2025 | Viewed by 208 | Submission Open
Keywords: mitochondria; redox signaling; reactive oxygen species (ROS); mitochondrial dynamics; bioenergetics; mitochondria– nuclear communication; aging; cell metabolism
Oxidative Stress in Pregnant Women and Fetuses submission deadline 30 Nov 2025 | Viewed by 202 | Submission Open
Keywords: metabolic programming; oxidative stress; antioxidants; mitochondria; inflammatory signaling; reactive oxygen species; reactive nitrogen species; placenta; trace elements; nutrition; gestation; offspring; pregnancy; breastfeeding; fetus
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
The Role of Oxidative Stress in Age-Related and Degenerative Eye Diseases
edited by
submission deadline 30 Nov 2025 | Viewed by 181 | Submission Open
Keywords: oxidative stress; age-related macular degeneration; retinal degeneration; reactive oxygen species; redox signaling; mitochondrial dysfunction; antioxidant therapy; artificial intelligence; multi-omics; biomarkers; vision science
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Lipid Peroxidation, Vegetable Oil Oxidation, and the Role of Plant Extracts in Enhancing Oxidative Stability
edited by and
submission deadline 30 Nov 2025 | Viewed by 178 | Submission Open
Keywords: oil oxidative stability; natural antioxidants; lipid peroxidation; surfactants; encapsulation
(This special issue belongs to the Section Aberrant Oxidation of Biomolecules)
Methodologies for Improving Antioxidant Properties and Absorption, 2nd Edition
edited by
submission deadline 30 Nov 2025 | Viewed by 167 | Submission Open
Keywords: bioavailability; targeted absorption; delivery systems; antioxidant structural modification; structure– activity relationship
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Artificial Intelligence and Other Bioinformatic Modern Technologies Approaches to the Study of Antioxidant Capacity in Food Production
edited by
submission deadline 5 Dec 2025 | Viewed by 501 | Submission Open
Keywords: artificial intelligence; bioinformatics; food processing; food quality; antioxidant capacity; big data
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
The Role of Oxidative Stress in Environmental Toxicity—2nd Edition
edited by Hariz Islas Flores
submission deadline 10 Dec 2025 | 1 articles | Viewed by 1340 | Submission Open
Keywords: environmental pollutants; oxidative stress biomarkers; water/air/soil pollution; environmental toxicity; ROS and RNS
Phenolics as Antioxidant Agents—2nd Edition
edited by
submission deadline 10 Dec 2025 | Viewed by 116 | Submission Open
Keywords: antioxidants; bioactive compounds; oxidative stress; structure– activity relationships (SARs); sustainable extraction; green chemistry; therapeutic potential; in vitro and in vivo models; food and biomedical applications
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Redox Regulation in Algae
edited by
submission deadline 10 Dec 2025 | Viewed by 78 | Submission Open
Keywords: algae; reactive oxygen species; redox regulation; stress responses; NADPH oxidases; antioxidants; redox-sensitive transcription factors
(This special issue belongs to the Section ROS, RNS and RSS)
Applications of Antioxidant Nanoparticles, 2nd Edition submission deadline 15 Dec 2025 | 8 articles | Viewed by 17881 | Submission Open
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Harnessing Antioxidants: Pioneering Approaches in Cardiovascular Disease Prevention and Therapy
edited by and
submission deadline 15 Dec 2025 | 1 articles | Viewed by 2502 | Submission Open
Keywords: oxidative stress; reactive oxygen species (ROS); antioxidants; cardiovascular diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Phytochemical Analysis and Evaluation of Antioxidant Properties in Medicinal Plants submission deadline 20 Dec 2025 | 7 articles | Viewed by 19266 | Submission Open
Keywords: antioxidant activity; phytochemicals in plants; medicinal plants; extraction; in vivo analysis; in vitro analysis
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Antioxidant and Anti-Inflammatory Properties of Mushrooms: From Structure to Functionality
edited by
submission deadline 20 Dec 2025 | 3 articles | Viewed by 9940 | Submission Open
Keywords: mushroom; antioxidants; metabolic syndrome; functional food; nutraceuticals; polysaccharides; phenolics; terpenoids
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Interplay of Microbiome and Oxidative Stress submission deadline 20 Dec 2025 | 3 articles | Viewed by 9736 | Submission Open
Keywords: microbiome; oxidative stress; antioxidants; gut microbiota; free radicals; reactive oxygen species; gut– brain axis; dysbiosis; microbial metabolites; mitochondrial function; probiotics; microbe– host interactions
The Use of Antioxidant-Rich Foods and Supplements in Disease Prevention submission deadline 20 Dec 2025 | 2 articles | Viewed by 8106 | Submission Open
Keywords: dietary antioxidants; bioactivity; metabolomics; human diet; xenobiotics; polyphenols; vitamins; health promotion
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Advances in Plant Redox Biology Research
edited by Yurong Xie and Ming Chang
submission deadline 20 Dec 2025 | Viewed by 201 | Submission Open
Keywords: plant redox biology; reactive oxygen species; reactive nitrogen species; plant development; environmental stress; abiotic/biotic stresses; host– microbe interactions
(This special issue belongs to the Section ROS, RNS and RSS)
Significance of Antioxidant Mechanisms in Intestinal Inflammation—2nd Edition submission deadline 20 Dec 2025 | Viewed by 149 | Submission Open
Keywords: antioxidant therapy; antioxidants; intestinal inflammation; oxidative stress; polyphenol; reactive oxygen/nitrogen species; redox homeostasis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants as Adjuvants for Inflammatory Bowel Disease Treatment submission deadline 22 Dec 2025 | 4 articles | Viewed by 5880 | Submission Open
Keywords: IBD; antioxidant; gut barrier; inflammation; natural compounds; microbiome; colon cancer; adjuvant; nutritional bioactive products; polyphenols
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Hydrogen and Oxidative Stress: Implications for Health and Longevity
edited by and
submission deadline 25 Dec 2025 | 1 articles | Viewed by 1223 | Submission Open
Keywords: molecular hydrogen (H2); oxidative stress; redox homeostasis; selective antioxidant; reactive oxygen species (ROS); aging and longevity; mitochondrial protection; cellular resilience; hydrogen therapy; inflammation and immunity; neurodegeneration; cardiovascular health; metabolic disorders; gene regulation; translational medicine; longevity
(This special issue belongs to the Section ROS, RNS and RSS)
Nitric Oxide and Redox Mechanisms
edited by , Paolo Ascenzi and
submission deadline 30 Dec 2025 | 6 articles | Viewed by 11963 | Submission Open
Keywords: nitric oxide; ROS and RNS; nitrosative stress; NO signaling; redox mechanisms
(This special issue belongs to the Section ROS, RNS and RSS)
Antioxidant Response in Aquatic Animals
edited by Martha Gabriela Gaxiola-Cortes
submission deadline 30 Dec 2025 | 8 articles | Viewed by 9744 | Submission Open
Keywords: antioxidant system; respiration; nutrition; culture; fish; aquatic animals; reactive oxygen species (ROS); superoxide dismutase (SOD)
Antioxidant and Anti-Inflammatory Potential of Plants in Cancer Treatment submission deadline 30 Dec 2025 | 3 articles | Viewed by 6705 | Submission Open
Keywords: phytochemical characterization; antioxidant and anti-inflammatory natural compounds and extracts; natural waste resources; horticultural or wild plants; medicinal plants; and edible plants; green selective extraction processes
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Lipid Peroxidation and Cancer submission deadline 30 Dec 2025 | Viewed by 149 | Submission Open
Keywords: lipid peroxidation; fatty acid metabolism; 4-hydroxynonenal (HNE); malondialdehyde (MDA); ferroptosis; carcinogenesis; cancer progression
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Male Reproductive Health submission deadline 31 Dec 2025 | 10 articles | Viewed by 22776 | Submission Open
Keywords: oxidative stress; antioxidant therapy; male reproductive health; male fertility; erectile dysfunction; prostatic disease; male ageing
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Therapies in Cardiovascular, Cardiorenal and Metabolic Diseases
edited by Kaushik P. Patel, Hong Zheng and
submission deadline 31 Dec 2025 | 5 articles | Viewed by 15146 | Submission Open
Keywords: antioxidant therapies; oxidative stress; cardiovascular diseases; cardiorenal diseases; metabolic diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Natural Antioxidants in Pharmaceuticals and Dermatocosmetology
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 12099 | Submission Open
Keywords: phytochemicals; antioxidant; pharmaceuticals; dermatocosmetic products; in vitro and in vivo evaluations; clinical trials
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Regulation in Cardiovascular Diseases submission deadline 31 Dec 2025 | 3 articles | Viewed by 8695 | Submission Open
Keywords: oxidative stress; mitochondria; metabolism; chronic inflammation; atherosclerosis; CVD; ROS
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Carotenoids in Health and Disease
edited by Kazutoshi Shindo
submission deadline 31 Dec 2025 | 3 articles | Viewed by 8606 | Submission Open
Keywords: antioxidant activities of carotenoids; analytical chemistry on carotenoids; reactive oxygen species (ROS) and disease; production of carotenoids
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Agri-Food Wastes as Natural Source of Bioactive Antioxidants: Fourth Edition submission deadline 31 Dec 2025 | 4 articles | Viewed by 8182 | Submission Open
Keywords: agri-food by-products; agri-food waste; nutraceuticals; functional foods; cosmeceutical products; sustainable practices; bioactive compounds; health effects
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Multi-Target Profile of Antioxidant Compounds, Including Repurposing and Combination Strategies—2nd Edition
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 7793 | Submission Open
Keywords: polypharmacology; multi-target ligands; rational drug; design repurposing; off-target effects; computational techniques
Antioxidant Activity of Polyphenolic Extracts
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 5667 | Submission Open
Keywords: antioxidant activity; polyphenols; plant extracts; oxidative stress
Role of Reactive Oxygen Species (ROS) in Tumor Microenvironment Modulation submission deadline 31 Dec 2025 | 3 articles | Viewed by 5616 | Submission Open
Keywords: reactive oxygen species; tumor microenvironment; stroma cells; functional genomics; spatial transcriptomics; single-cell sequencing; RNA-seq; cancer; diagnosis and prognosis; biomarkers
Antioxidant Research in Chile—2nd Edition submission deadline 31 Dec 2025 | 6 articles | Viewed by 5412 | Submission Open
Keywords: antioxidants; biotechnology; biomedicine; natural products; nutrition; oxidative stress; Chilean plants of economic importance; polyphenols; flavonoids; anthocyanins; phenolic acids; resveratrol; food waste; plant extracts; neuroinflammation; redox signaling; circular economy; ROS scavengers; antioxidants in industry; entrepreneurship; green startups
Oxidative Stress, Antioxidants, and Mechanisms in FLASH Radiotherapy submission deadline 31 Dec 2025 | 3 articles | Viewed by 5234 | Submission Open
Keywords: radiobiology and radiotherapy; ultra-high dose rate irradiation and the FLASH effect; molecular and cellular mechanisms; radiation-induced oxidative stress; reactive oxygen and nitrogen species; inflammatory processes; antioxidants and radioprotectors; pulse radiolysis; kinetics; physicochemical and biological processes; DNA damage; role of oxygen and the oxygen depletion hypothesis; modeling and experimental; FLASH particle therapy
Oxidative Stress in Rare Diseases: Mechanisms, Implications, and Therapeutic Opportunities submission deadline 31 Dec 2025 | 2 articles | Viewed by 4925 | Submission Open
Keywords: rare diseases; oxidative stress; free radicals; biomedicine; redox biomarkers; redox epigenetics; redox metabolism; redox control of protein function; ferroptosis
Selected Papers from the 2nd International Electronic Conference on Antioxidants (IECAN2025) submission deadline 31 Dec 2025 | 1 articles | Viewed by 4722 | Submission Open
Keywords: obesity; cardiovascular diseases; chronic disease; dietary prevention; antioxidants intake; gut microbiome; natural and synthetic antioxidants; antioxidant enzyme systems; antioxidant extraction
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