Special Issues

Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antioxidant Activity of Polyphenolic Extracts
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 6417 | Submission Open
Keywords: antioxidant activity; polyphenols; plant extracts; oxidative stress
Oxidative Stress in Rare Diseases: Mechanisms, Implications, and Therapeutic Opportunities submission deadline 31 Dec 2025 | 2 articles | Viewed by 5413 | Submission Open
Keywords: rare diseases; oxidative stress; free radicals; biomedicine; redox biomarkers; redox epigenetics; redox metabolism; redox control of protein function; ferroptosis
Natural Antioxidants in Animal Nutrition
edited by , , Chao Wang, Hao Zhang and Jingfei Zhang
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4932 | Submission Open
Keywords: antioxidants; animal; growth; metabolism; nutrition; oxidative stress; plant extracts
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Biology and Genomic Integrity
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 4884 | Submission Open
Keywords: redox biology; reactive oxygen species (ROS); oxidative stress; oxidative DNA damage; genome stability; DNA repair; hypermutation; antioxidant defense mechanisms; mitochondrial dysfunction; Saccharomyces cerevisiae; cellular adaptation; epigenetics; telomeres
From Field to Cell: Redox Mechanisms of Chemical Stressor Toxicity in Biological Systems submission deadline 31 Dec 2025 | 1 articles | Viewed by 3232 | Submission Open
Keywords: redox biology; environmental toxicology; chemical stressors; pesticides; redox signaling
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Metabolic Dysfunction and Oxidative Stress submission deadline 31 Dec 2025 | 2 articles | Viewed by 2691 | Submission Open
Keywords: iron; mitochondria; oxidative stress; inflammation; metabolism; free radicals
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Editorial Board Members’ Collection Series: Advances in Redox-Tools and Therapies in Cardiovascular Disease submission deadline 31 Dec 2025 | 2 articles | Viewed by 2554 | Submission Open
Keywords: cardiovascular disease; oxidative stress; inflammation; reactive oxygen species; redox signalling
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Respiratory Disorders
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2310 | Submission Open
Keywords: oxidative stress; lung; reactive oxygen species; reactive nitrogen species; acute lung injury; asthma; COPD; lung fibrosis; pulmonary silicosis; premature neonate
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Novel Strategies for Oxidative Stress Management: Dietary Interventions for Liver and Gut Health
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1812 | Submission Open
Keywords: antioxidant compounds; phytochemicals; dietary interventions; hepatic disease; intestinal disease; redox homeostasis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Super Oxide Dismutase (SOD) Isoenzymes and Reactive Oxygen Species (ROS) in Immuno-Pathophysiology
edited by Giuseppina Ruggiero and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1458 | Submission Open
Keywords: superoxide dismutase (SOD) isoenzymes; superoxide dismutase (SOD)1; cell signalling; cell metabolism; cell functions; cellular stress; disease pathogenesis
Natural Antioxidants in Functional Foods
edited by , Palmira De Bellis and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1292 | Submission Open
Keywords: polyphenols; functional foods; fermentation; antioxidant activity; anti-inflammatory activity
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Modulation of Biochemical, Cellular and Physiological Mechanisms in Response to Oxidative Stress in Animals submission deadline 31 Dec 2025 | 1 articles | Viewed by 969 | Submission Open
Keywords: animals; cell signaling; metabolism; cell death responses; oxidative damage
Radiation Exposure and Health: The Role of Oxidative Stress and Inflammatory Response submission deadline 31 Dec 2025 | 1 articles | Viewed by 957 | Submission Open
Keywords: radiation; inflammatory response; oxidative stress
Algal Antioxidants: Physiology, Metabolism, and Evolution
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 750 | Submission Open
Keywords: algae; antioxidant; oxidative stresses; algal physiology
Phenolic Antioxidants in Functional Foods and Nutraceuticals submission deadline 31 Dec 2025 | Viewed by 490 | Submission Open
Keywords: bioactive compounds; agri-food byproducts; in vitro assays; in vivo studies; green extraction; biological activities; safety assessment; industrial application
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Antioxidants and Dietary Nutrition: Emerging Trends, and Clinical Applications submission deadline 31 Dec 2025 | Viewed by 431 | Submission Open
Keywords: antioxidants; oxidative stress; chronic disease prevention; dietary strategies; bioavailability
Antioxidant Properties of Functional Foods
edited by Konstantinos G. Adamopoulos and
submission deadline 31 Dec 2025 | Viewed by 422 | Submission Open
Keywords: antioxidant; extraction; bioavailability; processing; optimization; functional food; phytochemicals
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Emerging Trends in Antioxidant Nutraceuticals submission deadline 31 Dec 2025 | 1 articles | Viewed by 419 | Submission Open
Keywords: nutraceuticals; diabetes; cancer; oxidative stress; inflammation; antioxidant
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Metabolism and Epigenetics: A Potential Dual Interaction in the Microenvironment of Solid Tumors
edited by , , and Sebastiano Giallongo
submission deadline 31 Dec 2025 | Viewed by 310 | Submission Open
Keywords: metabolomics; tumor cell metabolism; tumor microenvironment; cell communication; cell signaling; epigenetics; post-translational modifications; cancer therapy
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Development and Application of Detection Methods for Reactive Oxygen Species and Antioxidants submission deadline 31 Dec 2025 | Viewed by 293 | Submission Open
Keywords: antioxidant extraction; antioxidant assay; sensors for reactive oxygen species (ROS); ROS scavenger assays; biological samples; oxidative stress status; nutritional value; food analysis; bioassays; enzymatic assays; redox cycle; cell imaging
(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)
The Role of Dietary Antioxidants in Alleviating Oxidative Stress and Inflammation for Enhanced Immunity in Animals
edited by Yanka D. Karamalakova and
submission deadline 31 Dec 2025 | Viewed by 284 | Submission Open
Keywords: antioxidants; antioxidant feeding; insect meal; growth performance; digestible energy; nutrient digestibility; blood biochemistry; oxidative stress (OS); lipid peroxidation (MDA); ROS/RNS; superoxide dismutase (SOD); catalase (CAT); glutathione (GSH); glutathione peroxidase (GPx); inflammation markers; total antioxidant capacity (TAC); meat; milk; eggs quality
Oxidative Stress and Mitochondrial Dysfunction in Metabolic Disorders
edited by , and Hugo J Alves-Figueiredo
submission deadline 31 Dec 2025 | Viewed by 245 | Submission Open
Keywords: metabolic diseases; oxidative stress; mitochondrial dysfunction; antioxidant therapies; lifestyle interventions; gene therapies; mitochondrial transfer therapies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Natural Products and Peptides in Cosmetics submission deadline 31 Dec 2025 | Viewed by 240 | Submission Open
Keywords: cosmetics; herbal extracts; natural products; peptides; synthesis; isolation; oxidative stress; emulsions; nanoparticles; fibroblasts; ageing
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Antioxidants for Skin Health—2nd Edition
edited by Rubia Casagrande
submission deadline 31 Dec 2025 | Viewed by 213 | Submission Open
Keywords: skin inflammation; cytokine; skin oxidative stress; Nrf2; reduced glutathione; ultraviolet irradiation; drug delivery; flavonoid; terpenes; specialized pro-resolution lipid mediators
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioavailability of Antioxidants: From Omics Insights to Health Outcomes submission deadline 31 Dec 2025 | Viewed by 208 | Submission Open
Keywords: bioavailability; nutrigenomics; metabolomics; gut microbiota; dietary polyphenols; functional foods; biotransformation; systems biology; antioxidants; bioactivity
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Studies on Antioxidants and Anti-Aging Substances Using Model Organisms and Cell Cultures
edited by
submission deadline 31 Dec 2025 | Viewed by 204 | Submission Open
Keywords: antioxidants; anti-aging substances and natural products; experimental animals; 3D cell culture models; organoids; acting mechanisms; antioxidant genes; autophagy; proteasome
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Regulation of Plant Growth and Development
edited by Judit Dobránszki and
submission deadline 31 Dec 2025 | Viewed by 146 | Submission Open
Keywords: plant biology; ascorbate; free-radical scavenging; glutathione; heat shock proteins; melatonin; oxidative stress; plant growth and development; redox homeostasis; RNP; ROS; plant stress mitigation; plant stress adaptation; transcription factors
(This special issue belongs to the Section ROS, RNS and RSS)
Hydrogen Sulfide and Its Role in Inflammatory and Degenerative Joint Diseases
edited by Guenter Steiner and Burkhard Klösch
submission deadline 31 Dec 2025 | Viewed by 145 | Submission Open
Keywords: hydrogen sulfide; inflammation; antioxidant; osteoarthritis; rheumatoid arthritis; degeneration; chondrocyte; monocyte; fibroblast; drug development
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Biomarkers of Oxidative Stress in Lung Disease
edited by
submission deadline 31 Dec 2025 | Viewed by 119 | Submission Open
Keywords: oxidative stress; reactive oxygen species; reactive nitrogen species; antioxidants; lung inflammation; bronchial inflammation; COPD; asthma; lung fibrosis; mitochondria
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Adaptive Responses in Space Medicine and Physiology
edited by
submission deadline 31 Dec 2025 | Viewed by 111 | Submission Open
Keywords: antioxidant defense  ; microgravity  ; oxidative stress  ; radiation  ; space medicine  ; space physiology
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Phytochemicals for Promoting Human Health and Well-Being submission deadline 10 Jan 2026 | 6 articles | Viewed by 7881 | Submission Open
Keywords: antioxidant phytochemicals; oxidative stress; health promotion; chronic disease; functional foods; nutraceuticals
Antioxidant Effects of Natural Compounds on Cell Metabolism
edited by Ester Tellone and Annamaria Russo
submission deadline 12 Jan 2026 | 3 articles | Viewed by 5444 | Submission Open
Keywords: antioxidants; metabolic pathways; dietary intake; blood cells; bioactive compounds
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Mitochondrial Oxidative Stress in Aging and Disease—2nd Edition submission deadline 15 Jan 2026 | 7 articles | Viewed by 18509 | Submission Open
Keywords: mitochondrial oxidative stress in aging; mitochondrial oxidative stress in age-related or metabolic diseases; mitochondrial signaling via ROS in diseases; mitochondrial oxidative stress and genomic instability; mitochondrial oxidative stress and inflammation; antioxidants as novel therapeutic approaches; mitochondrial pathologies; aging; mitochondrial
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Hydrophilic and Lipophilic Antioxidants in Foods and Food Processing
edited by
submission deadline 15 Jan 2026 | Viewed by 179 | Submission Open
Keywords: antioxidant activity; antioxidant capacity; antioxidant mechanisms; carotenoids; polyphenols; vitamin C; vitamin E; impact of food processing
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Antioxidant Systems in Plants
edited by , Ilda Jesús Casimiro Felicio and
submission deadline 20 Jan 2026 | 2 articles | Viewed by 2035 | Submission Open
Keywords: enzymatic antioxidants; non-enzymatic antioxidants; nitro-oxidative stress; reactive oxygen species; reactive nitrogen species; ROS and RNS signaling
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Exploring the Role of Polyphenols in Oxidative Stress and Cellular Protection submission deadline 20 Jan 2026 | 1 articles | Viewed by 1960 | Submission Open
Keywords: polyphenol; oxidative stress; cellular signaling; metabolic pathways
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants and Multifunction Photoprotection—2nd Edition submission deadline 20 Jan 2026 | 1 articles | Viewed by 178 | Submission Open
Keywords: natural and synthetic antioxidants; sunscreens; multifunctional products; safety and efficacy establishment; product technologies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Advances in Peroxiredoxin Biology
edited by Mikael Molin and Cecilia Picazo
submission deadline 23 Jan 2026 | 1 articles | Viewed by 159 | Submission Open
Keywords: oxidative stress; aging; age-related diseases; H2O2 signaling; redox regulation
(This special issue belongs to the Section Antioxidant Enzyme Systems)
Interplay Between Gut Microbiota and Oxidative Stress
edited by
submission deadline 25 Jan 2026 | Viewed by 264 | Submission Open
Keywords: gut microbiota; redox; human health; gut homeostasis
Redox Balance and Autophagy in Neuroinflammation submission deadline 26 Jan 2026 | Viewed by 261 | Submission Open
Keywords: oxidative stress/oxidative damage  ; reactive oxygen species (ROS)  ; redox homeostasis  ; autophagy  ; lysosomal clearance  ; proteinopathies  ; neuroinflammation  ; neurological disorders  ; cellular homeostasis  ; neuroprotection
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Effect of Oxidative Stress on Reproduction and Development—3rd Edition submission deadline 30 Jan 2026 | 5 articles | Viewed by 6917 | Submission Open
Keywords: free radicals and antioxidants; oxidative stress in male and female reproduction; mitochondria; gametogenesis; assisted reproduction; thermal fertility limit (TFL); climate change; one-health; biodiversity conservation and sustainability; reproduction; development and nutrigenomics; methods for reactive oxygen species detection and antioxidant property determination.
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Diabetic Retinopathy
edited by Tatsuya Mimura
submission deadline 30 Jan 2026 | 1 articles | Viewed by 1862 | Submission Open
Keywords: diabetic retinopaty; oxidative stress; antioxidants; inflammation; environmental factor
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Something Is Rotten in the State of Redox—2nd Edition submission deadline 30 Jan 2026 | Viewed by 395 | Submission Open
Keywords: antioxidants; antioxidant mechanisms; ageing and age-related diseases; oxidative stress; redox biology
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Environmental Risk Factors and Oxidative Stress in the Retina
edited by
submission deadline 30 Jan 2026 | Viewed by 287 | Submission Open
Keywords: environment; pollution; oxidative stress; retina
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Signaling in Chronic Diseases
edited by
submission deadline 30 Jan 2026 | Viewed by 213 | Submission Open
Keywords: redox signaling; chronic oxidative diseases; redox modulator; oxidative stress; antioxidant; redox homeostasis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Regulation by One-Electron Transferring Flavoproteins: Catalysis and Metabolism submission deadline 30 Jan 2026 | Viewed by 104 | Submission Open
Keywords: flavin mononucleotide (FMN); flavin adenine dinucleotide (FAD); single-electron transfer; free radicals; reactive oxygen species (ROS); mitochondrial respiration; photosynthesis; nitrogen fixation; electron flux bifurcation; immune response; semiquinone
(This special issue belongs to the Section Antioxidant Enzyme Systems)
Redox Regulation in Animal Reproduction
edited by Zhongliang Jiang
submission deadline 31 Jan 2026 | 9 articles | Viewed by 33086 | Submission Open
Keywords: spermatogenesis; follicular atresia; oocyte maturation; granulosa cells; hormone regulation; autophagy; apoptosis; oxidative stress; signaling regulation
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Natural Antioxidants and Aquatic Animal Health—2nd Edition
edited by
submission deadline 31 Jan 2026 | 9 articles | Viewed by 9439 | Submission Open
Keywords: natural antioxidants; oxidative stress; medicinal plants; aquatic animals; feed additives
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Diabetic Retinopathy and Oxidative Stress: Molecular Mechanisms, Diagnostic Strategies, and Advances in Antioxidant Therapies submission deadline 31 Jan 2026 | 2 articles | Viewed by 3790 | Submission Open
Keywords: diabetic retinopathy; natural antioxidants; oxidative stress; epigenetic mechanisms; biomarkers; diagnostic methods
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
The Effect of Nutritional Intervention and Diet on Oxidative Stress and Human Diseases
edited by , Cristina Bouzas and
submission deadline 31 Jan 2026 | 2 articles | Viewed by 3372 | Submission Open
Keywords: nutrition; diet; oxidative stress; inflammation; human chronic diseases; supplements; cardiovascular diseases; diabetes; obesity
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
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