Oxidative Stress During Physical Activity

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 1297

Special Issue Editor


E-Mail Website
Guest Editor
Unit of Biology and Genetics of Movement, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis 6, 00135 Rome, Italy
Interests: redox homeostasis; antioxidant systems; redox signaling; oxidative stress response proteins; skeletal/cardiac muscle; muscle adaptation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Physical activity is widely recognized for its profound impact on physiological systems, enhancing both performance and overall health through intricate subcellular adaptations. Recent advancements have significantly deepened our understanding of the molecular mechanisms underlying these benefits. Nevertheless, there is still a crucial need to fully elucidate the complex processes driving these adaptations.

Emerging research highlights the pivotal role of oxidative stress, particularly reactive oxygen species (ROS), in mediating the effects of physical activity. ROS, integral to cellular signaling and homeostasis, are byproducts of metabolism, the levels of which are influenced by exercise. While they are essential in moderation, excessive ROS production, notably oxygen radicals, can disrupt redox balance, leading to cellular damage. Such oxidative stress is implicated in various pathological conditions, underscoring the delicate balance necessary for optimal health outcomes.

This Special Issue aims to gather original research and reviews that delve into the interplay between redox balance and physical activity in both physiological adaptation and pathological states. While human studies are the primary focus, contributions involving animal models will also be considered, with the aim of expanding our understanding across different biological contexts.

We invite researchers to contribute their insights in order to further unravel the intricate relationship between oxidative stress and physical activity, ultimately advancing our knowledge, so that we can enhance human health and performance.

Dr. Ivan Dimauro
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • physical activity
  • exercise
  • oxidative stress
  • reactive oxygen species (ROS)
  • redox balance
  • cellular damage
  • skeletal muscle

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

17 pages, 2985 KiB  
Article
Molecular, Physical, and Technical Performance Response After a Competitive Match in Male Professional Soccer Players
by Alessandra Modesti, Rosamaria Militello, Alice Tanturli, Alice Santi, Massimo Gulisano, Cristian Petri, Luca Pengue, Alessio Pellegrino, Pietro Amedeo Modesti and Simone Luti
Antioxidants 2025, 14(1), 73; https://doi.org/10.3390/antiox14010073 - 9 Jan 2025
Viewed by 894
Abstract
Background: Male professional soccer players frequently compete in multiple matches weekly, and each match significantly impacts their homeostasis, health, and performance. This study evaluates players response at 48 h post-match by combining biological and GPS data. Investigating biochemical and performance metrics offers insights [...] Read more.
Background: Male professional soccer players frequently compete in multiple matches weekly, and each match significantly impacts their homeostasis, health, and performance. This study evaluates players response at 48 h post-match by combining biological and GPS data. Investigating biochemical and performance metrics offers insights into the physical demands of high-intensity exercise, essential for optimizing performance, recovery, and overall athlete health. Methods: The study involved an Italian “Serie A” team, and we assessed players’ effort during a single match using GPS data and compared it to “Serie A” averages. Additionally, we evaluated oxidative stress and metabolism 48 h after the match. Results: At 48 h post-match, there were no signs of oxidative stress and changes in salivary IgA levels, but total antioxidant potential was significantly low. Moreover, increased plasma metabolites linked to energy production were also observed. Conclusions: The results indicate that 48 h after a match in “Serie A”, well-trained athletes showed no oxidative stress, to the detriment of the antioxidant potential, along with increased metabolites crucial for energy production. Combining GPS and metabolic analysis enhances player performance, informs tactical decisions, and supports team success, fostering data-driven approaches in soccer. Full article
(This article belongs to the Special Issue Oxidative Stress During Physical Activity)
Show Figures

Figure 1

Back to TopTop