Oxidative Stress During Physical Activity

Dear Colleagues,

Physical activity is widely recognized for its profound impact on physiological systems, enhancing both performance and overall health through intricate subcellular adaptations. Recent advancements have significantly deepened our understanding of the molecular mechanisms underlying these benefits. Nevertheless, there is still a crucial need to fully elucidate the complex processes driving these adaptations.

Emerging research highlights the pivotal role of oxidative stress, particularly reactive oxygen species (ROS), in mediating the effects of physical activity. ROS, integral to cellular signaling and homeostasis, are byproducts of metabolism, the levels of which are influenced by exercise. While they are essential in moderation, excessive ROS production, notably oxygen radicals, can disrupt redox balance, leading to cellular damage. Such oxidative stress is implicated in various pathological conditions, underscoring the delicate balance necessary for optimal health outcomes.

This Special Issue aims to gather original research and reviews that delve into the interplay between redox balance and physical activity in both physiological adaptation and pathological states. While human studies are the primary focus, contributions involving animal models will also be considered, with the aim of expanding our understanding across different biological contexts.

We invite researchers to contribute their insights in order to further unravel the intricate relationship between oxidative stress and physical activity, ultimately advancing our knowledge, so that we can enhance human health and performance.

Dr. Ivan Dimauro
Guest Editor

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