Antioxidants in Cardiovascular Medicine: Emerging Trends and Future Perspectives
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 93
Special Issue Editors
Interests: thrombosis; fibrinogen; oxidative stress; protein structure
Special Issues, Collections and Topics in MDPI journals
Interests: redox markers; antioxidant capacity; post-translational oxidative modification; ROS sources
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to introduce our upcoming Special Issue, which will explore the evolving role of antioxidants in cardiovascular medicine. Oxidative stress is increasingly recognized as a key contributor to the pathogenesis and progression of cardiovascular diseases (CVDs). As such, the potential of antioxidant-based therapies to mitigate oxidative damage and improve cardiovascular outcomes has garnered significant scientific and clinical interest.
This Special Issue aims to provide a comprehensive perspective on the latest advancements in antioxidant research, with a focus on novel compounds, molecular mechanisms, and clinical applications in CVD management. We welcome original research and review articles that address the following:
- The role of oxidative stress and redox signaling in cardiovascular pathophysiology, including endothelial dysfunction, inflammation, myocardial remodeling, and vascular aging;
- Innovative antioxidant therapies, including synthetic and natural compounds, targeted delivery systems, and combination approaches;
- Preclinical and clinical evidence evaluating the efficacy of antioxidants in conditions such as atherosclerosis, hypertension, heart failure, and ischemic heart disease;
- Dietary and lifestyle interventions that enhance antioxidant defenses and reduce cardiovascular risk;
- Emerging biomarkers and novel methodologies for assessing oxidative stress and antioxidant efficacy in cardiovascular research;
- The role of artificial intelligence (AI) and machine learning (ML) in predicting oxidative stress-related cardiovascular risks, personalizing antioxidant therapies, and analyzing large-scale omics data;
- Computational modeling-and AI-driven drug discovery for the identification of new antioxidant compounds and their cardioprotective effects;
- Big data analytics for evaluating population-based trends and the effectiveness of antioxidant-based interventions in real-world cardiovascular health.
By gathering contributions from experts across diverse fields, this Special Issue aims to bridge the gap between fundamental research and clinical applications, fostering a deeper understanding of antioxidant strategies in cardiovascular health. We encourage multidisciplinary perspectives, including insights from pharmacology, molecular biology, nutrition, artificial intelligence, and clinical medicine.
We look forward to your valuable contributions and to advancing the discussion on how antioxidant-based interventions, enhanced by AI-driven approaches, can shape the future of cardiovascular medicine.
Dr. Matteo Becatti
Dr. Claudia Fiorillo
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cardiovascular disease
- CVD
- atherosclerosis
- hypertension
- heart failure
- ischemic heart disease
- vascular aging
- myocardial remodeling
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