Oxidative Stress and Skin Disorders: Therapeutic Potential of Antioxidants
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 68
Special Issue Editor
Interests: melanin; melanocyte; melanosome; pigmentation; tyrosinase; ultraviolet light
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is known that the energy of ultraviolet radiation is absorbed by amino acids and vitamins in the skin and generates various kinds of reactive oxygen species (ROS). In addition, even without exposure to ultraviolet radiation, a substantial amount of superoxide, which is generated when mitochondria produce ATP, is converted into ROS by enzymes and metal ions in the skin. Although ROS are necessary for some physiological functions, they also accelerate aging and can cause various diseases. For example, many research studies have shown that hydrogen peroxide is deeply involved in triggering vitiligo, a cutaneous depigmentary disorder. Hydrogen peroxide has a longer half-life than other ROS and thus accumulates in the skin. If the hydrogen peroxide scavenging ability is reduced for some reason, the concentration of hydrogen peroxide in the skin increases, resulting in the death of melanocytes that produce melanin pigmentation and the detachment of melanocytes from the basement membrane, which reduces the production of cutaneous pigmentation. Therefore, the research and development of topical and/or oral agents or active ingredients that directly eliminate various kinds of ROS, or that activate the intracellular ROS scavenging system, are desirable. In this Special Issue, we invite submissions of research papers on skin diseases or related basic research using skin cells in which ROS have been suggested to be involved. Research on antioxidants and other agents that may prevent or ameliorate skin aging and diseases is also welcome.
Prof. Dr. Hideya Ando
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- ultraviolet radiation
- reactive oxygen species
- oxidative stress
- skin disorders
- skin aging
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
