Plant Polyphenols in Human Health: Emerging Insights for Future Therapeutic Strategies
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 58
Special Issue Editors
Interests: natural compounds; polyphenols; metabolic disorders; obesity; cancer; antimicrobial; skin; cosmetics
Special Issues, Collections and Topics in MDPI journals
Interests: antimicrobial; antimicrobial resistance; natural compounds; oxidative stress; polyphenols; skin health
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Plant polyphenols have garnered significant attention for their potential health benefits. This Special Issue delves into the multifaceted roles of these compounds in human health. Classically, the therapeutic and preventive properties of plant polyphenols have been mostly attributed to their antioxidant and anti-inflammatory effects. However, more recent research has demonstrated their pleiotropic effects through their ability to modulate gut microbiota and various metabolic targets and pathways related to cellular energy management, signal transduction, cell proliferation, and epigenetic regulation. This issue sheds light on how these interactions influence crucial metabolic processes and contribute to disease prevention. The collection collates the latest studies on various polyphenolic compounds and their potential metabolites, including phenolic acids, flavonoids, stilbenoids, and lignans, and their mechanisms of action in combating chronic diseases such as metabolic syndrome, diabetes, hypertension, liver diseases, neurodegenerative disorders, and dermatological affections. Furthermore, the issue addresses the challenges related to the bioavailability of polyphenols and discusses innovative strategies to enhance their therapeutic efficacy. By integrating recent findings, this compilation underscores the therapeutic potential of plant polyphenols and advocates for their inclusion in future health interventions.
Prof. Dr. Vicente Micol
Guest Editor
Dr. Francisco Javier Álvarez-Martínez
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- polyphenols
- antioxidant properties
- anti-inflammatory effects
- metabolic stress
- chronic disease prevention
- gut microbiota
- polyphenols metabolites
- bioavailability
- skin health
- novel therapies
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