Inflammatory Mediators and Oxidative Balance in Vascular Pathophysiology
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 210
Editor
Interests: atherosclerosis; hypertension; vasodilation; vascular inflammation; adhesion molecule
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Vascular pathophysiology, including hypertension, atherosclerosis, and related cardiovascular disorders, is closely associated with chronic inflammation and dysregulated oxidative balance. Excessive production of reactive oxygen species (ROS) and impaired antioxidant defense systems contribute to endothelial dysfunction, vascular remodeling, and disease progression. In parallel, inflammatory mediators, including cytokines, chemokines, and adhesion molecules, interact with redox signaling pathways, amplifying vascular injury and compromising vascular homeostasis. Despite significant advances, the complex interplay between inflammatory responses and oxidative stress in vascular systems remains incompletely understood.
This Special Issue aims to provide a comprehensive platform for advancing our understanding of how inflammatory mediators and oxidative balance regulate vascular physiology and pathology. The scope is designed to capture both mechanistic insights and translational perspectives, without being overly broad or restrictive. In particular, this Special Issue encourages studies that explore molecular signaling pathways, cellular interactions, and therapeutic targets involved in redox regulation and inflammation-driven vascular dysfunction.
In addition to conventional pharmacological and molecular approaches, contributions incorporating perspectives from oriental medicine are welcome, especially those investigating natural products and herbal formulations with antioxidant and anti-inflammatory properties. The application of network pharmacology to elucidate multi-target and system-level mechanisms is encouraged but not mandatory. Both experimental and computational approaches that deepen our understanding of vascular oxidative and inflammatory regulation are welcome.
We look forward to receiving your valuable contributions.
Prof. Dr. Yun Jung Lee
Guest Editor
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Keywords
- inflammatory mediators
- oxidative stress
- vascular pathophysiology
- endothelial dysfunction
- antioxidants
- redox signaling
- oriental medicine
- herbal medicine
- network pharmacology
- cardiovascular disease
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