The Role of Dietary Antioxidants in Alleviating Oxidative Stress and Inflammation for Enhanced Immunity in Animals

A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: 31 December 2025 | Viewed by 19

Special Issue Editors


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Guest Editor
Medical Faculty, Trakia University, Stara Zagora, Bulgaria
Interests: natural antioxidants; synthetic drugs; antioxidant compounds; cellular protective mechanism; cellular functionality; oxidative stress; ROS/RNS; lipid peroxidation; inflammation; ROS/RNS metabolisms; fibrosis; preterm pregnancy; neurodegenerative disease; cancer
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Guest Editor
College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Interests: nutrition and metabolism (amino acids); oxidative stress and redox biology; gut microbiome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue of Antioxidants, "The Role of Dietary Antioxidants in Alleviating Oxidative Stress and Inflammation for Enhanced Immunity in Animals”, aims to provide a comprehensive, multidisciplinary overview of the current knowledge in this field.

Over the past 10 years, more and more studies have established the application of dietary antioxidants and their biological actions to eliminate damage from reactive oxygen species (ROS; superoxide (●O2), hydrogen peroxide (H2O2), hydroxyl (●OH) radicals)), reactive nitrogen species (RNS; nitric oxide (●NO)), and oxidative stress, which are associated with the development of subclinical diseases and depressed indicators in farm animals (cows, sheep, goats, swine, pigs, hens, chickens). The application of natural and synthetic (additive) antioxidants (polyphenols, flavonoids, vitamins, trace elements, fatty acids and phytonutrients, etc.; insect meals) as additives in feed, supplements, and foods presents farmers, producers and animal researchers with hope to improve productivity and the quality of animal products (meat, dairy products, eggs). The accumulation of dietary antioxidants in the body tissues and gastrointestinal tract of farm animals can improve the quality and shelf life of meat, milk, and eggs by fully regulating the body's redox homeostasis.
Therefore, a complete understanding of the ways to eliminate radical imbalance and oxidative changes through antioxidant diets in cases of nutritional deficiencies; climate change (drought); parasitic infestation; or animal species genetics, sex, age, etc., can be applied to enhance the health of animals, the quality of their products, and, consequently, human health.

Original scientific articles, short reports, hypotheses, and literature reviews describing the role of antioxidant dietary nutrition in neutralizing free radicals, remedying oxidative-induced disorders, and directly monitoring biological markers will be considered. We encourage the submission of scientific and clinical studies that will contribute to the progress of this complex field and allow us to outline future directions for work.

Potential topics could include the following: antioxidant defense; dietary intervention; bioactive compounds; feeding activities;  prooxidants; stress factors, redox balance; oxidation; ROS/RNS; livestock production; meat, milk and egg quality; health and well-being.

Dr. Yanka D. Karamalakova
Prof. Dr. Jie Yin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidants
  • antioxidant feeding
  • insect meal
  • growth performance
  • digestible energy
  • nutrient digestibility
  • blood biochemistry
  • oxidative stress (OS)
  • lipid peroxidation (MDA)
  • ROS/RNS
  • superoxide dismutase (SOD)
  • catalase (CAT)
  • glutathione (GSH)
  • glutathione peroxidase (GPx)
  • inflammation markers
  • total antioxidant capacity (TAC)
  • meat, milk, eggs quality

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Published Papers

This special issue is now open for submission.
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