Novel Strategies for Oxidative Stress Management: Dietary Interventions for Liver and Gut Health
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 5
Special Issue Editors
Interests: functional foods; bioactive compounds; antioxidant capacity; sterols; phytochemicals; bioaccessibility; bioavailability; bioactivity; cell cultures; chemoprevention; oxidative stress; eryptosis; food by-products
Special Issues, Collections and Topics in MDPI journals
Interests: bioactive compounds; nutraceuticals; intestinal health; in vitro models; molecular biology; bioavailability; simulated gastrointestinal digestion; antioxidant; anti-inflammatory
Special Issue Information
Dear Colleagues,
Oxidative stress is a critical driver in the pathogenesis and progression of liver and gastrointestinal diseases, including nonalcoholic fatty liver disease, hepatocellular carcinoma, and inflammatory bowel diseases. Growing evidence highlights the potential of dietary interventions to modulate oxidative stress pathways, restore redox homeostasis, and slow or prevent disease progression. Bioactive dietary compounds with antioxidant properties act on multiple biological levels, influencing inflammatory signaling, mitochondrial function, endogenous antioxidant systems, and gut–liver axis communication.
This Special Issue aims to showcase innovative research on dietary strategies to mitigate oxidative stress and improve liver and gut health. We welcome original research articles and comprehensive reviews that investigate the molecular mechanisms by which dietary components attenuate oxidative damage. Topics of interest include the regulation of antioxidant defense networks, activation of redox-sensitive transcription factors, modulation of inflammatory pathways, and role of gut microbiota in maintaining redox balance across hepatic and intestinal systems.
Submissions may include preclinical models (cellular and animal) and human intervention studies. By bringing together mechanistic insights and translational findings, this Special Issue seeks to support the development of evidence-based dietary recommendations for the prevention and management of oxidative stress-related liver and gastrointestinal disorders.
Dr. Antonio Cilla
Guest Editor
Dr. Mussa Makran
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antioxidant compounds
- phytochemicals
- dietary interventions
- hepatic disease
- intestinal disease
- redox homeostasis
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