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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Redox Regulation in COPD: Therapeutic Implications of Antioxidants

edited by

Samuel Santos Valença

submission deadline 31 Oct 2025 | Viewed by 84 | Submission Open

Keywords: COPD; oxidative stress; antioxidants; pulmonary diseases; therapeutics

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Vitamins, Antioxidants, and Neurodegeneration: Exploring Protective Strategies in Brain Health

edited by

Maria Morello

submission deadline 31 Oct 2025 | Viewed by 76 | Submission Open

Keywords: neurodegenerative diseases; alzheimer's disease; parkinson's disease; amyotrophic lateral sclerosis (ALS); aging populations; vitamins; antioxidants; oxidative stress; neuroinflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress Induced by Micro(Nano)plastics

edited by

Lavinia Casati

Alessandro Villa

and

Marco Parolini

submission deadline 31 Oct 2025 | Viewed by 75 | Submission Open

Keywords: micro(nano)plastics; oxidative stress; One Health; in vitro and in vivo models; organisms; cellular microenvironment

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Chronic Pain and Oxidative Stress

edited by

Olga Pol

submission deadline 31 Oct 2025 | Viewed by 70 | Submission Open

Keywords: analgesia; antioxidants; chemotherapy; heme oxygenase 1; neuropathy; nociception; Nrf2 transcription factor; oxidative stress; pain

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Cardiovascular Medicine: Emerging Trends and Future Perspectives

edited by

Matteo Becatti

and

Claudia Fiorillo

submission deadline 31 Oct 2025 | Viewed by 68 | Submission Open

Keywords: cardiovascular disease; CVD; atherosclerosis; hypertension; heart failure; ischemic heart disease; vascular aging; myocardial remodeling

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Olive Antioxidants: Extraction, Biological Activity and Practical Applications—3rd Edition

edited by

Juan Fernández-Bolaños

and

Alejandra Bermudez-Oria

submission deadline 31 Oct 2025 | Viewed by 67 | Submission Open

Keywords: antioxidant effect; olive oil; olive by-products; olive leaves; polyphenols; carotenoids; polysaccharide– polyphenol complexes; vitamin E; health; Mediterranean diet

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Advances in the Astonishing World of Phytochemicals: State-of-the-Art for Antioxidants—3rd Edition

edited by

Antonella D'Anneo

and

Marianna Lauricella

submission deadline 31 Oct 2025 | Viewed by 66 | Submission Open

Keywords: bioactive compounds; phytochemicals; antioxidant properties; oxidative and nitrosative stress; anticancer action; antimicrobial properties; anti-inflammatory actions

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Role of Oxidative Stress in Cardiac Remodeling and Heart Failure—3rd Edition

edited by

Marina Politi Okoshi

Elida Paula Benquique Ojopi

and

Luana Urbano Pagan

submission deadline 31 Oct 2025 | Viewed by 45 | Submission Open

Keywords: oxidative stress; heart disease; cardiac remodeling; signaling pathways; remodeling; left ventricular dysfunction; heart failure; cardiovascular disease; myocardial damage

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Compounds from Natural Sources with Antioxidant and Anti-Inflammatory Potential

edited by

Chun Guang Li

submission deadline 31 Oct 2025 | Viewed by 34 | Submission Open

Keywords: antioxidant; anti-inflammatory; natural compounds; isolation; extraction; molecular mechanism; synergistic effect; clinical trial; bioavailability; analytical method; pharmacodynamics; pharmacokinetics

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

NADPH Oxidases (NOXs)

edited by David W. Stepp

submission deadline 10 Nov 2025 | 6 articles | Viewed by 7823 | Submission Open

Keywords: NADPH oxidases; reactive oxygen species; redox signaling; cardiovascular diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Alcohol-Induced Oxidative Stress in Health and Disease, 2nd Edition

edited by

Marco Fiore

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1723 | Submission Open

Keywords: alcohol; alcohol use disorder; reactive oxygen species; antioxidant defense

Oxidative Stress from Environmental Exposures

edited by

Giulia Squillacioti

Valeria Bellisario

and

Federica Ghelli

submission deadline 20 Nov 2025 | Viewed by 113 | Submission Open

Keywords: environmental exposures; human health; air pollution; lifestyle; oxidative stress; particulate matter; environmental stressors

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Hepatic Diseases

edited by

Miquel Mulero

submission deadline 21 Nov 2025 | 1 articles | Viewed by 1272 | Submission Open

Keywords: oxidative stress; hepatic diseases; liver fibrosis; reactive oxygen species (ROS); mitochondrial dysfunction; lipid peroxidation; antioxidant defense; non-alcoholic fatty liver disease (NAFLD); alcoholic liver disease; hepatoprotective strategies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants from Food and Food Wastes for Nutraceutical, Pharmaceutical and Cosmetic Fields

edited by Monica Locatelli and

Vincenzo Disca

submission deadline 25 Nov 2025 | 4 articles | Viewed by 3528 | Submission Open

Keywords: phenolic compounds; analytical methods; bioactivities; green extraction; functional ingredients; food supplements; by-products and up-cycled ingredients; nutraceutical; cosmetics; bioaccessibility

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Antioxidant Compounds and Health Benefits of Mediterranean Functional Food

edited by

Stefania D'Angelo

submission deadline 25 Nov 2025 | 2 articles | Viewed by 2558 | Submission Open

Keywords: antioxidants; anti-inflammatory; anti-obesity; functional food; human health; Mediterranean diet; nutraceuticals; nutrition; oxidative stress; phytochemicals; polyphenols

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress in Animal Reproduction and Nutrition

edited by

Fang Chen

and

Jun Chen

submission deadline 28 Nov 2025 | Viewed by 513 | Submission Open

Keywords: oxidative stress; antioxidants; animal reproduction; nutritional regulation; livestock and poultry; mouse or rat model; antioxidant mechanisms; oxidative stress mechanisms

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Retinal Diseases—2nd Edition

edited by

Francisco J. Romero

and Jorge M. Barcia

submission deadline 30 Nov 2025 | 7 articles | Viewed by 11602 | Submission Open

Keywords: retinal diseases; antioxidants; oxygen species; extracellular vesicles; miRNA

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Therapy for Obesity-Related Diseases

edited by

Seyed Khosrow Tayebati

submission deadline 30 Nov 2025 | 7 articles | Viewed by 10360 | Submission Open

Keywords: obesity; inflammation; oxidative stress; organ damage; natural antioxidants; synthetic antioxidants; mechanisms of action; therapeutical approaches

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress-Related Mechanisms and Antioxidant Therapy in Cancer

edited by

and

submission deadline 30 Nov 2025 | 3 articles | Viewed by 8488 | Submission Open

Keywords: ascorbate; vitamin C; cancer therapy; cancer prevention; antioxidants; prooxidants; oxidative stress; epigenetic activity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Novel Antioxidants for Animal Nutrition—2nd Edition

edited by

Matteo Dell'Anno

and

Luciana Rossi

submission deadline 30 Nov 2025 | 4 articles | Viewed by 6610 | Submission Open

Keywords: nutrition; functional diets; innovative antioxidants; feed additives; natural extracts; disease prevention; oxidative stress; one health

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Free Radicals, Antioxidants, and Oxidative Stress in Aging and Age-Related Diseases—2nd Edition

edited by

Abdelouahed Khalil

and

Tamas Fulop

submission deadline 30 Nov 2025 | 3 articles | Viewed by 4778 | Submission Open

Keywords: aging; oxidative stress; age-related diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Innovative Technologies for Detecting Antioxidant Properties and Oxidative Stabilization of Agri-Food Products and Plant Extracts

edited by

Chao Hui Feng

submission deadline 30 Nov 2025 | 3 articles | Viewed by 3526 | Submission Open

Keywords: green extraction; plant extracts; bioactive compounds; flavonoids; polyphenols; detection technologies; antioxidant activity

(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)

The Interaction Between Gut Microbiota and Host Oxidative Stress

edited by

Jie Yin

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2650 | Submission Open

Keywords: oxidative stress; antioxidants; gut microbiome; immunity

Inhibition of Oxidative Stress and Related Signaling Pathways in Neuroprotection—2nd Edition

edited by

Maja Jazvinšćak Jembrek

and

Josipa Vlainić

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2094 | Submission Open

Keywords: neuroprotection; neurotoxicity; antioxidative vs. proxidative; oxidative stress; signaling pathways; redox metals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Antioxidants in Hypoxia and Human Pathophysiology Settings, 2nd Edition

edited by

Rodrigo L. Castillo

and Alejandro Gonzalez-Candia

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1866 | Submission Open

Keywords: tissue hypoxia; reperfusion injury; hypoxic preconditioning; oxidative stress; antioxidants; hypoxic programing; microRNA; clinical hypoxic settings

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Glutathione and Health: From Development to Disease

edited by

Ying Chen

and Vasilis K. Vasiliou

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1714 | Submission Open

Keywords: glutathione; antioxidants; antioxidant enzymes; oxidative stress; redox biology; molecular biology; cellular biology; biochemistry; development; disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Eye Diseases

edited by

Dhirendra Pratap Singh

and

Eri Kubo

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1424 | Submission Open

Keywords: oxidative stress; antioxidants; reactive oxygen species; redox signaling; inflammatory cell death; age-related blinding diseases; glaucoma; cataract; age-related macular degeneration; gene regulation; retinal disorder; dry eye disorder; corneal diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Microalgae FoodOmics and FeedOmics: Antioxidant Enrichment, ROS Modulation, and Health-Boosting Applications

edited by

Clementina Sansone

and

Francesca Sansone

submission deadline 30 Nov 2025 | Viewed by 487 | Submission Open

Keywords: microalgae; bioactive compounds; antioxidants; antioxidant metabolism; antioxidant biosynthesis; omics; vitamins; probiotics; prebiotics; postbiotics; drug delivery; signal transduction; gut/brain axis

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidant Foods and Cardiometabolic Health—3rd Edition

edited by

Yolanda Aguilera Gutiérrez

and

Maria Angeles Martín-Cabrejas

submission deadline 30 Nov 2025 | Viewed by 474 | Submission Open

Keywords: cardiometabolic diseases; antioxidant foods; bioactive compounds; functional foods; biological activity; bioaccessibility

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Inflammation in Neurologic Diseases

edited by

Adriana Bulboaca

submission deadline 30 Nov 2025 | Viewed by 209 | Submission Open

Keywords: oxidative stress; nitrosative stress; neuroinflammation; neurodegeneration; neuronal apoptosis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Metabolism and Mitochondrial Dysfunction in Metabolic Diseases—3rd Edition

edited by

Gina Cavaliere

and

Giovanna Trinchese

submission deadline 30 Nov 2025 | Viewed by 118 | Submission Open

Keywords: mitochondria function; oxidative processes; metabolic diseases; reactive oxygen species; therapeutic approaches; mitochondrial integrity; energy production; mitochondrial bioenergetic; metabolism; mitochondrial dynamic

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Berry Antioxidants in Health and Disease—2nd Edition

edited by

Dorothy Klimis-Zacas

and

Sarah A. Johnson

submission deadline 30 Nov 2025 | Viewed by 78 | Submission Open

Keywords: berries; antioxidants; polyphenols; berry metabolites; oxidative stress; chronic diseases; cardiovascular disease; metabolic syndrome; diabetes mellitus; cancer; neurodegenerative disease; gut microbiome

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Products to Mitigate Oxidative Stress and Inflammation in Non-Communicable Intestinal Diseases

edited by

Carlos Martins-Gomes

and

Amélia M. Silva

submission deadline 30 Nov 2025 | Viewed by 74 | Submission Open

Keywords: natural bioactives; phytochemicals; oxidative stress; inflammation; non-communicable intestinal diseases; colorectal cancer; inflammatory bowel diseases; signalling pathways

Bioactive Antioxidants: Structural Characterization, Synthetic Pathways, and Clinical Applications

edited by

Jolanta Flieger

submission deadline 30 Nov 2025 | Viewed by 39 | Submission Open

Keywords: bioactive antioxidants; therapeutic potential; synthetic strategies; structural characterization

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative Stress in Cell Senescence

edited by

Sara Cruciani

submission deadline 30 Nov 2025 | Viewed by 37 | Submission Open

Keywords: stem cells; cell senescence; regenerative medicine; antioxidant strategies; age-related diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advances in Mitochondrial Redox Biology—Second Edition

edited by

Masuko Ushio-Fukai

submission deadline 30 Nov 2025 | Viewed by 30 | Submission Open

Keywords: mitochondria; redox signaling; reactive oxygen species (ROS); mitochondrial dynamics; bioenergetics; mitochondria– nuclear communication; aging; cell metabolism

Hydrogen Sulfide, Reactive Sulfur Species, and Donor Compounds: Natural and Synthetic Tools for Physiology and Disease

edited by

Giuseppe Caliendo

and

Angela Corvino

submission deadline 30 Nov 2025 | Viewed by 30 | Submission Open

Keywords: hydrogen sulfide; H2S donors; H2S hybrid compounds; H2S sources; pharmacological tools; H2S signaling

Methodologies for Improving Antioxidant Properties and Absorption, 2nd Edition

edited by

Daniela Tofani

submission deadline 30 Nov 2025 | Viewed by 20 | Submission Open

Keywords: bioavailability; targeted absorption; delivery systems; antioxidant structural modification; structure– activity relationship

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Lipid Peroxidation, Vegetable Oil Oxidation, and the Role of Plant Extracts in Enhancing Oxidative Stability

edited by

Daniele Sanna

and

Angela Fadda

submission deadline 30 Nov 2025 | Viewed by 16 | Submission Open

Keywords: oil oxidative stability; natural antioxidants; lipid peroxidation; surfactants; encapsulation

(This special issue belongs to the Section Aberrant Oxidation of Biomolecules)

Artificial Intelligence and Other Bioinformatic Modern Technologies Approaches to the Study of Antioxidant Capacity in Food Production

edited by

Giuseppe Perretti

submission deadline 5 Dec 2025 | Viewed by 361 | Submission Open

Keywords: artificial intelligence; bioinformatics; food processing; food quality; antioxidant capacity; big data

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Redox Regulation in Algae

edited by

Kim Gwang Hoon

submission deadline 10 Dec 2025 | Viewed by 3 | Submission Open

Keywords: algae; reactive oxygen species; redox regulation; stress responses; NADPH oxidases; antioxidants; redox-sensitive transcription factors

(This special issue belongs to the Section ROS, RNS and RSS)

Phytochemical Analysis and Evaluation of Antioxidant Properties in Medicinal Plants

edited by

Magdalena Jeszka-Skowron

Agnieszka Zgoła-Grześkowiak

Tomasz Grześkowiak

and

Robert Frankowski

submission deadline 20 Dec 2025 | 7 articles | Viewed by 11408 | Submission Open

Keywords: antioxidant activity; phytochemicals in plants; medicinal plants; extraction; in vivo analysis; in vitro analysis

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidant and Anti-Inflammatory Properties of Mushrooms: From Structure to Functionality

edited by

Michał Swieca

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3910 | Submission Open

Keywords: mushroom; antioxidants; metabolic syndrome; functional food; nutraceuticals; polysaccharides; phenolics; terpenoids

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Interplay of Microbiome and Oxidative Stress

edited by

Julio Plaza-Díaz

Lourdes Herrera-Quintana

and

Héctor Vázquez Lorente

submission deadline 20 Dec 2025 | 3 articles | Viewed by 2820 | Submission Open

Keywords: microbiome; oxidative stress; antioxidants; gut microbiota; free radicals; reactive oxygen species; gut– brain axis; dysbiosis; microbial metabolites; mitochondrial function; probiotics; microbe– host interactions

Significance of Antioxidant Mechanisms in Intestinal Inflammation—2nd Edition

edited by

Alba Rodríguez-Nogales

and

María Elena Rodríguez Cabezas

submission deadline 20 Dec 2025 | Viewed by 55 | Submission Open

Keywords: antioxidant therapy; antioxidants; intestinal inflammation; oxidative stress; polyphenol; reactive oxygen/nitrogen species; redox homeostasis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advances in Plant Redox Biology Research in China

edited by Yurong Xie and Ming Chang

submission deadline 20 Dec 2025 | Viewed by 26 | Submission Open

Keywords: plant redox biology; reactive oxygen species; reactive nitrogen species; plant development; environmental stress; abiotic/biotic stresses; host– microbe interactions

(This special issue belongs to the Section ROS, RNS and RSS)

Antioxidants as Adjuvants for Inflammatory Bowel Disease Treatment

edited by

Marcello Chieppa

and

Angelo Santino

submission deadline 22 Dec 2025 | 3 articles | Viewed by 3112 | Submission Open

Keywords: IBD; antioxidant; gut barrier; inflammation; natural compounds; microbiome; colon cancer; adjuvant; nutritional bioactive products; polyphenols

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Nitric Oxide and Redox Mechanisms

edited by

Massimiliano Coletta

, Paolo Ascenzi and

Giovanna De Simone

submission deadline 30 Dec 2025 | 4 articles | Viewed by 5193 | Submission Open

Keywords: nitric oxide; ROS and RNS; nitrosative stress; NO signaling; redox mechanisms

(This special issue belongs to the Section ROS, RNS and RSS)

Antioxidant Response in Aquatic Animals

edited by Martha Gabriela Gaxiola-Cortes

submission deadline 30 Dec 2025 | 4 articles | Viewed by 5151 | Submission Open

Keywords: antioxidant system; respiration; nutrition; culture; fish; aquatic animals; reactive oxygen species (ROS); superoxide dismutase (SOD)

Antioxidant and Anti-Inflammatory Potential of Plants in Cancer Treatment

edited by

Brigitte Deguin

Lorenza Trabalzini

and

Rosa Tundis

submission deadline 30 Dec 2025 | 1 articles | Viewed by 3833 | Submission Open

Keywords: phytochemical characterization; antioxidant and anti-inflammatory natural compounds and extracts; natural waste resources; horticultural or wild plants; medicinal plants; and edible plants; green selective extraction processes

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

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