Antioxidant Defenses and Retinal Inflammation in Diabetic Retinopathy
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 1
Special Issue Editor
Special Issue Information
Dear Colleagues,
Diabetic retinopathy is a severe microvascular complication of diabetes and the leading cause of blindness in working-age adults. Oxidative stress and inflammation are key pathological events that contribute to the development and progression of diabetic retinopathy. The retina, with its high oxygen consumption and high level of polyunsaturated fatty acids, is particularly susceptible to oxidative stress, which can lead to retinal cell death and dysfunction.
The body’s natural antioxidant defenses play a crucial role in protecting the retina from this damage. However, in diabetic retinopathy, these systems are often compromised, leading to an imbalance between pro-oxidants and antioxidants. This oxidative imbalance triggers a cascade of inflammatory responses, including the activation of various immune cells and the production of pro-inflammatory cytokines, further exacerbating retinal injury.
This Special Issue aims to bring together the latest research on the link between antioxidant defenses and retinal inflammation in diabetic retinopathy. We invite submissions on original research and review articles that explore topics such as the mechanisms of oxidative stress in causing retinal inflammation, the role of specific antioxidants and antioxidant enzymes, and the potential of novel therapeutic strategies targeting these pathways to treat or prevent diabetic retinopathy. We look forward to your contributions.
Dr. Devy Deliyanti
Guest Editor
Manuscript Submission Information
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Keywords
- retinal injury
- diabetic retinopathy
- retinal inflammation
- cell death
- antioxidant
- pro-oxidants
- oxidative stress
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