Peroxiredoxins
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Antioxidant Enzyme Systems".
Deadline for manuscript submissions: 31 January 2027 | Viewed by 1899
Special Issue Editor
Special Issue Information
Dear Colleagues,
Chronic oxidative stress and dysregulated redox signaling are linked to the pathogenesis of numerous diseases, including cancer and neurodegenerative disorders. Peroxiredoxins (Prxs), as key antioxidant enzymes located throughout cellular organelles, serve as critical regulators of cellular redox homeostasis, influencing survival, apoptosis, and stress adaptation in diverse biological contexts. In cancer, Prxs are emerging as both biomarkers and therapeutic targets, given their roles in modulating tumor progression and stemness. Similarly, in neurobiology, Prxs protect neurons from oxidative stress-induced damage and are implicated in processes such as neuroinflammation and cognitive decline. Despite significant progress being made in our understanding of Prx biology, the precise molecular mechanisms by which they exert their protective and regulatory effects remain an active area of investigation.
Here, we invite you to contribute original research or comprehensive reviews on the diverse functions of Peroxiredoxins. This Special Issue aims to bring together current findings that deepen our understanding of Prxs in cellular and molecular contexts. Topics of interest include, but are not limited to, the role of Peroxiredoxins in neuronal systems, their regulatory mechanisms in cancer stem cell biology, and innovative therapeutic strategies targeting Prxs. By consolidating these studies, this Special Issue aims to become a valuable resource for advancing research and fostering new insights into the critical functions of Peroxiredoxins.
Prof. Dr. Dong-Seok Lee
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- peroxiredoxins
- oxidative stress
- neuron
- neuroinflammation
- stemness
- cancer
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