Oxidative Stress in Cardiovascular Diseases
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 30 April 2026
Special Issue Editors
Interests: cardiovascular disease; vascular remodeling; atherosclerosis; hypertension; heart failure; therapeutic target; cell signaling; antioxidant compound
Special Issues, Collections and Topics in MDPI journals
Interests: metabolic diseases; aging; molecular nutrition; mitochondrial metabolism; iron homeostasis; ROS
Special Issues, Collections and Topics in MDPI journals
Interests: iron metabolism; oxidative stress; intervention strategies; ferroptosis; meta-analysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiovascular diseases (CVDs) continue to be the primary contributor to global mortality. Dysregulated oxidative stress is a fundamental contributor to the initiation and progression of numerous cardiac and vascular pathologies, presenting a promising target for novel interventions. Current research, including recent findings on redox signaling in various CVDs, reveals persistent obstacles. These encompass the limited clinical success of conventional antioxidant therapies, challenges in achieving targeted tissue delivery, the insufficient drug-like properties of new candidates, and unresolved molecular pathways that affect their translational potential.
This Special Issue invites original research, reviews, and meta-analyses that explore innovative findings on redox balance in the cardiovascular system and novel strategies targeting cardiovascular diseases. We also seek submissions covering the discovery of natural or synthetic antioxidant compounds, the design and evaluation of advanced compound delivery systems, and pharmacological studies on their bioavailability and safety. Investigations into signaling mechanisms, biomarker discovery, preclinical models of CVD, and clinical translation strategies for antioxidant-based therapies are also of great interest. The collective aim is to highlight pioneering strategies for overcoming current translational barriers in redox-based cardiovascular medicine.
Dr. Yongting Luo
Dr. Junjie Luo
Dr. Peng An
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cardiovascular disease
- oxidative stress
- antioxidant compound
- mechanism
- therapeutic target
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