Antioxidant and Antidiabetic Activities of Plant Matrices: Methods, Mechanisms, and Translational Relevance
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: 31 March 2026 | Viewed by 48
Special Issue Editor
2. Department of Production Engineering, Wroclaw University of Economics and Business, Komandorska 118/120, 53‑345 Wrocław, Poland
Interests: nutraceuticals and functional foods; medicinal plants; bioactive compounds; HPLC; LC-MS; nutrition; antioxidant agent; prebiotics; probiotics; symbiotics; bioavailability in vitro
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue focuses on the rigorous, harmonized assessment of antioxidant, antidiabetic, and anti-inflammatory activities across diverse plant matrices—from conventional crops to wild, neglected, and underutilized species. We welcome studies that strengthen the connection between laboratory evidence and practical relevance by linking compositions, processing, formulation/delivery approaches, and clearly defined endpoints. While plant-derived agents at the interface of redox biology and metabolic health continue to demonstrate promise, progress is often limited by methodological fragmentation and insufficiently standardized workflows. Accordingly, we explicitly encourage both chemical assays and in vitro studies.
We particularly invite first-time screenings and in vitro investigations of previously uncharacterized plant sources, as well as systematic evaluations of side streams and by-products to broaden sustainable bioactive portfolios. Submissions may address activity profiling alongside the effects of processing and formulation on stability, bioaccessibility, and bioavailability—for example, drying technologies, ultrasound, microwave treatment, fermentation, and food-grade carriers/encapsulation. Cellular or mechanistic data can enhance interpretability but are not required, as are studies that clearly report composition–activity relationships.
To improve reproducibility and enable meta-analyses, we especially value method harmonization (fit-for-purpose assay selection, reference standards, calibration/quality control) and transparent reporting (sample provenance, processing history, matrix effects, dose ranges). Data structures that facilitate reuse—e.g., shared metadata and assay parameters—are encouraged. By assembling robust chemical and in vitro evidence and, where possible, connecting it to mechanistic or formulation insights, this Special Issue aims to build a coherent evidence base from composition to function and to inform the future development of reliable, plant-based interventions relevant to metabolic health.
Dr. Sabina Lachowicz-Wiśniewska
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- antioxidant assays
- antidiabetic activity
- α-glucosidase
- α-amylase
- DPP-IV
- antiglycation/AGEs
- tea (Camellia sinensis)
- wild plants
- neglected and underutilized species (NUS)
- stachys
- root and tuber crops
- ultrasound
- microwave
- bioavailability
- metabolomics
- layer-by-layer
- hydrogels
- alginate
- pectin
- chitosan
- zein
- processing by-products
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