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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Progress and Challenges in the Antibiotic Treatment of Infections

edited by Marina Bubonja-Sonje

submission deadline 24 Aug 2025 | 2 articles | Viewed by 1638 | Submission Open

Keywords: antimicrobial therapy; antimicrobial stewardship; antimicrobial resistance; rapid microbiological diagnostics

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Use and Antimicrobial Stewardship for Children in the Emergency Department

edited by

Michael Barrett

and

Spyridon Karageorgos

submission deadline 31 Aug 2025 | 7 articles | Viewed by 31782 | Submission Open

Keywords: pediatric ED; ambulatory; antimicrobial stewardship; antibiotic use; antimicrobial resistance; point-of-care testing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobials Use: Clinical Safety to Environmental Risk—Learning from One Health Approach

edited by

Anabela Almeida

Leonor M. Meisel

and

Ana Fortuna

submission deadline 31 Aug 2025 | 7 articles | Viewed by 30155 | Submission Open

Keywords: antimicrobials; antifungals; antiviral; environment; antimicrobial resistance; pharmacokinetics; risk-assessment; prioritisation; One-Health

Antimicrobial Activity of Secondary Metabolites Produced in Nature

edited by

Dragana Božić

and

Mirjana D. Marčetić

submission deadline 31 Aug 2025 | 8 articles | Viewed by 26463 | Submission Open

Keywords: antimicrobial resistance; multidrug-resistant pathogens; secondary metabolites; natural products; terpenes; phenolic compounds; polyketides; antimicrobial peptides; bacteriocins; bacterial/fungal toxins

(This special issue belongs to the Section Plant-Derived Antibiotics)

Membranes to Fight Drug-Resistant Microbes

edited by

Nermina Malanovic

submission deadline 31 Aug 2025 | 6 articles | Viewed by 17716 | Submission Open

Keywords: antimicrobial peptides; membrane-active compounds; mode of action; lipidoids; vaccines

(This special issue belongs to the Section Antimicrobial Peptides)

From Detection to Treatment: Navigating Urinary Tract Infections with Antibiotics

edited by

Eleonora Nicolai

submission deadline 31 Aug 2025 | 3 articles | Viewed by 13591 | Submission Open

Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria

edited by

Daniel Gyamfi Amoako

and

Linda Bester

submission deadline 31 Aug 2025 | 8 articles | Viewed by 11244 | Submission Open

Keywords: antimicrobial resistance mechanism; mobile genetic element; horizontal gene transfer; resistome; evolution; molecular phylogenetics; genomics; bioinformatics analysis; next-generation sequencing

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Healthcare-Associated Infections (HAIs): Prevention, Control and Surveillance

edited by

Maria Bagattini

submission deadline 31 Aug 2025 | 5 articles | Viewed by 9266 | Submission Open

Keywords: healthcare-associated infections (HAIs); infection prevention and control; antimicrobial resistance; HAIs management and control; carbapenem resistant (CR) Enterobacterales; carbapenem resistant (CR) Acinetobacter baumannii

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotics: Fighting Disease and Promoting Health by Embracing the Two Sides of the Same Coin

edited by

Chrysoula Voidarou

Elisavet Stavropoulou

and

Eugenia Bezirtzoglou

submission deadline 31 Aug 2025 | 2 articles | Viewed by 6603 | Submission Open

Keywords: antibiotics; probiotics; antibacterial activity; functional food; natural compounds; natural antimicrobials; microbiome; antimicrobial resistance; resistome

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Bacterial Resistome and Antimicrobial Resistance in Animal Infectious Diseases

edited by

Paolo Capozza

Nicola Pugliese

and

Maria Tempesta

submission deadline 31 Aug 2025 | 1 articles | Viewed by 5841 | Submission Open

Keywords: bacterial resistome; antimicrobial resistance; animal Infectious diseases; veterinary medicine

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Applications of Green Nanotechnology in Biomedicine and the Environment

edited by

María Gabriela Paraje

, Maria Teresa A. Alvarez Aliaga, Natalia Lorena Guiñazú and

Fernando Gomes de Souza Junior

submission deadline 31 Aug 2025 | 1 articles | Viewed by 4583 | Submission Open

Keywords: green nanoparticles; eco-friendly synthesis; antimicrobial activity; anti-biofilm strategies; antimicrobial resistance; synergistic effects; drug delivery systems; nanotoxicity; sustainable nanotechnology; environmental applications; one health approach

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Activity of Extracts from Plants, 2nd Edition

edited by

Lucia Recinella

and

Sheila Leone

submission deadline 31 Aug 2025 | 2 articles | Viewed by 4562 | Submission Open

Keywords: antimicrobial activity; metabolomic fingerprint; bioinformatics

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Resistance in Hospital-Acquired Infections

edited by Andreea-Loredana Golli,

Ovidiu Zlatian

and

Alice Elena Ghenea

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2924 | Submission Open

Keywords: healthcare-associated infections; multi-drug resistance; epidemiology; antimicrobial therapy; patient outcomes; infection prevention and control strategies

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotics and the Evolution of Resistance: Insights into Horizontal Gene Transfer

edited by

Günther Koraimann

and

Elisabeth Grohmann

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2107 | Submission Open

Keywords: antibiotic resistance spread and evolution; pathogens; one health; plasmids; integrative conjugative elements; bacteriophages; conjugative transfer; transduction

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Discovery of Novel Antimicrobial Peptides Using Machine Learning and Molecular Dynamic Simulations

edited by

Lei Zhao

Liang Zhao

and

Fei Pan

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1700 | Submission Open

Keywords: antimicrobial peptide; computational design; machine learning; deep learning; molecular dynamic simulations; de novo generation

(This special issue belongs to the Section Antimicrobial Peptides)

Discovery and Development of Novel Antibacterial Agents—2nd Edition

edited by

Kui Zhu

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1369 | Submission Open

Keywords: antibiotic discovery; antibacterial target; mode of action; natural product

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Treatment and Antibiotic Resistance of Enterococcus Infections, 2nd Edition

edited by

Giovanni Boccia

Gianluigi Franci

and

Biagio Santella

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1277 | Submission Open

Keywords: antibiotics; antimicrobial resistance; enterococcus faecium; enterococcus faecalis; drug resistance; epidemiologic studies; endocarditis

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Advances in Infective Endocarditis Research: From Bench to Bedside

edited by Joya-Rita Hindy

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1011 | Submission Open

Keywords: infective endocarditis; prosthetic valve endocarditis; cardiac implantable electronic devices; recurrent infective endocarditis; valvular heart disease; cardiac surgery; molecular diagnostics; innovative drug delivery; antimicrobial resistance; suppressive therapy

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Stewardship Implementation Strategies

edited by

Massimo Sartelli

submission deadline 31 Aug 2025 | 4 articles | Viewed by 823 | Submission Open

Keywords: antibiotic stewardship; implementation; hospital settings

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Use and Antibiotic Resistance in Dermatology

edited by

Ayman Grada

and

Christopher Bunick

submission deadline 31 Aug 2025 | Viewed by 691 | Submission Open

Keywords: antibiotics; resistance; dermatology; antimicrobial resistance; bacteria

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Challenges and Strategies for the Antibiotic Resistance Crisis

edited by

Manuel Simões

and

Marc Maresca

submission deadline 31 Aug 2025 | Viewed by 662 | Submission Open

Keywords: antibiotics stewardship; antimicrobial use; antibiotics resistance; novel antimicrobial agents; multidisciplinary antimicrobial strategies; antibiotic clinical studies; artificial intelligence strategies

Multidurg Resistant Enterobacterales: Mechanisms, Epidemiology and Diagnostics

edited by José Manuel Ortiz De La Rosa and

Mustafa Sadek

submission deadline 31 Aug 2025 | Viewed by 494 | Submission Open

Keywords: multidrug-resistant Enterobacterales; dissemination; detection; β -lactamases; genomics

Ionic Liquids as Novel Antimicrobial Agents

edited by

Patrick-Julian Mester

and Tomasz Cłapa

submission deadline 31 Aug 2025 | Viewed by 382 | Submission Open

Keywords: ionic liquids; antimicrobials; biocides; bacteria; fungi; viruses; structure– activity relationship

(This special issue belongs to the Section Novel Antimicrobial Agents)

Novel (Bio)electroanalytical Methods and Related Outcomes of Antibiotics Determination

edited by

Mihaela Buleandrǎ

and

Dana Elena Popa

submission deadline 31 Aug 2025 | Viewed by 321 | Submission Open

Keywords: antibiotics; electrochemical (bio)sensors; electroanalysis; redox behavior; electrochemical instrumentation; modified electrodes

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Antibiotics for Primary Care Practice

edited by Reza Nassiri

submission deadline 31 Aug 2025 | Viewed by 289 | Submission Open

Keywords: primary care practice; nursing home practice; remote practice; antibiotic prescription habits; antibiotic resistance in clinical practice; public health consequences of antibiotic resistance; antibiotics stewardship practices; elements of safe practice

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Epidemiology, Drug Resistance, and Virulence in Zoonotic Pathogens

edited by

Sonsiray Alvarez-Narvaez

Laura Huber

and Susan Sanchez

submission deadline 31 Aug 2025 | Viewed by 244 | Submission Open

Keywords: antimicrobial resistance; epidemiology; molecular epidemiology; virulence; host– pathogen interactions; zoonosis; one health

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Stewardship—from Projects to Standard of Care

edited by Gesche Först and Franky Buyle

submission deadline 31 Aug 2025 | Viewed by 211 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial use; antibiotics; implementation; efficacy; quality; antimicrobial prescribing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Advancing and Standardising Antimicrobial Susceptibility and Resistance Detection Methodology

edited by

Owen B. Spiller

submission deadline 31 Aug 2025 | Viewed by 161 | Submission Open

Keywords: antimicrobial susceptibility testing; resistance screening; rapid diagnostics; clinical; veterinary; environmental; validation

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

New Inhibitors for Overcoming Antimicrobial Resistance

edited by

Humberto Medeiros Barreto

and

Sofia Santos Costa

submission deadline 31 Aug 2025 | Viewed by 158 | Submission Open

Keywords: antimicrobial resistance; resistance mechanisms; inhibitors; enzymatic inhibitors; efflux; biofilms

Urinary Tract Infections: Diagnosis, Etiology, Antibiotic Treatment, and Current Trends in Antimicrobial Resistance

edited by Michael Mihailov Petrov

submission deadline 31 Aug 2025 | Viewed by 108 | Submission Open

Keywords: urinary tract infections (UTIs); etiology; epidemiology; microbiological diagnosis; antimicrobial resistance; treatment; molecular genetic methods; resistotypes; rapid identification; uropathogens

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Global Perspectives on Antimicrobial Stewardship: Lessons from Multidisciplinary and Transdisciplinary Approaches

edited by

Gigi Lim

submission deadline 31 Aug 2025 | Viewed by 101 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; clinical expertise; public health; AI

Antimicrobial Resistance of Staphylococcus spp. in Animals: A One Health Perspective

edited by Gi Yong Lee

submission deadline 5 Sep 2025 | Viewed by 151 | Submission Open

Keywords: staphylococci; molecular epidemiology; antimicrobial resistance; One Health; multiomics

(This special issue belongs to the Section Antibiotics in Animal Health)

Strategies to Counteract Mono- and Polymicrobial Biofilm-Related Infections

edited by

Giovanni Di Bonaventura

submission deadline 10 Sep 2025 | 1 articles | Viewed by 997 | Submission Open

Keywords: antimicrobials; anti-biofilm; biofilm control; biofilm-associated infections

(This special issue belongs to the Section Antibiofilm Strategies)

Pharmacologic Management of MDR Respiratory and Bacteraemic Infections

edited by

Demosthènes A. Makris

and Konstantinos D. Mantzarlis

submission deadline 15 Sep 2025 | Viewed by 365 | Submission Open

Keywords: pneumonia; bacteraemia; intensive care; MDR infections; antibiotics

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Discovery and Development of the Novel Antimicrobial Agent—2nd Volume

edited by

Zeinab Khalil

submission deadline 15 Sep 2025 | Viewed by 268 | Submission Open

Keywords: antibiotics; bacteria; fungi; plants; multidrug-resistant pathogens; natural products; mode of action; mechanism of action; drug target; drug development

(This special issue belongs to the Section Novel Antimicrobial Agents)

Nanomaterials in Oral Health: Novel Antimicrobial Treatments in Dentistry

edited by

Liliana Burlibasa

and

Serena Riela

submission deadline 15 Sep 2025 | Viewed by 201 | Submission Open

Keywords: nanomaterials; oral health; antimicrobial treatments; dentistry; genotoxicity

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Antimicrobial Resistance in the Era of Climate Change

edited by

Natalia G. Vallianou

and Eleni Geladari

submission deadline 15 Sep 2025 | Viewed by 187 | Submission Open

Keywords: climate change; extremes in temperature; antimicrobial resistance (AMR)

Surveillance of Carbapenem-Resistant Microbes and Strategies to Combat Them

edited by Daniela Cejas and Marcela Radice

submission deadline 15 Sep 2025 | Viewed by 142 | Submission Open

Keywords: antibiotic resistance; epidemiology; carbapenemases; carbapenem resistance; enterobacterales; acinetobacter baumannii; resistance plasmids; surveillance; genomics; high-risk clones

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Choices for Pediatric Infections

edited by Theodouli Stergiopoulou

submission deadline 15 Sep 2025 | Viewed by 83 | Submission Open

Keywords: pediatric; neonatal infectious diseases; antimicrobial agents; antibiotic treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic-Associated Dysbiosis and Management

edited by

Yuseok Moon

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3847 | Submission Open

Keywords: dysbiosis; antibiotics; immunity; microbiota; intervention

Strategies for the Design of Hybrid-Based Antimicrobial Compounds

edited by

Vuyolwethu Khwaza

Sibusiso Alven

and

Blessing Atim Aderibigbe

submission deadline 20 Sep 2025 | 1 articles | Viewed by 674 | Submission Open

Keywords: hybrid compounds; antimicrobial agents; antibacterial agents; antifungal activity; antiviral activity; in vitro evaluation; structure– activity relationship (SAR); bioactive molecules; nanoformulations; targeted drug delivery; pharmacological screening; clinical studies

(This special issue belongs to the Section Novel Antimicrobial Agents)

Therapeutic Drug Monitoring of Antibiotics in the Hospital Environment

edited by Natalia Brucker

submission deadline 25 Sep 2025 | 2 articles | Viewed by 1377 | Submission Open

Keywords: therapeutic drug monitoring (TDM); antibiotics; hospital environment; healthcare

Plants, Lichens, Fungi, and Algae Extracts and Derivatives with Antimicrobial Properties for Nutrition and Health

edited by

Violeta Popovici

Emma Adriana Ozon

Andreea Letitia Arsene

and

Verginica Schroder

submission deadline 30 Sep 2025 | 8 articles | Viewed by 19245 | Submission Open

Keywords: antimicrobial and antibiofilm activity; plants/lichens/fungi/algae extracts and derived products with antibacterial; antifungal; antiviral; antiprotozoal and antihelmintic properties; antimicrobial metabolites: quantification and characterization; pharmaceutical formulation; in vivo and in vitro testing; essential oils with antimicrobial properties for the pharmaceutical and food industry; functional foods; plant-based diet; case studies; prevention and treatment of infectious diseases with plant-derived products

(This special issue belongs to the Section Plant-Derived Antibiotics)

State-of-the-Art in Antimicrobial Research in Greece

edited by

Paraskevi Papaioannidou

submission deadline 30 Sep 2025 | 5 articles | Viewed by 14279 | Submission Open

Keywords: antibiotics; antimicrobials; antibiotic surveillance; antimicrobial resistance; biofilms; one health

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Honey: Antimicrobial and Anti-infective Function

edited by

Niels Cremers

and

Juraj Majtan

submission deadline 30 Sep 2025 | 5 articles | Viewed by 13579 | Submission Open

Keywords: antimicrobial activity; biofilms; infections; clinical applications

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Resistance and Infections in Animals

edited by

John B. Kaneene

submission deadline 30 Sep 2025 | 4 articles | Viewed by 13233 | Submission Open

Keywords: antimicrobial resistance; mechanisms; humane and societal concerns; risk factors

(This special issue belongs to the Section Antibiotics in Animal Health)

Artificial Intelligence and Antimicrobial Resistance: Innovation, Global Challenges and the Future of Healthcare

edited by

Fabio Scarpa

and

Francesco Branda

submission deadline 30 Sep 2025 | 2 articles | Viewed by 10196 | Submission Open

Keywords: antimicrobial resistance; artificial intelligence; digital health; drug discovery; patient-centric care; therapeutic innovations

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotics and Infectious Respiratory Diseases, 2nd Edition

edited by

Francesco Di Gennaro

Fabrizio Palmieri

and

Gina Gualano

submission deadline 30 Sep 2025 | 5 articles | Viewed by 10137 | Submission Open

Keywords: infectious respiratory diseases; pulmonary tuberculosis; COVID-19 pneumonia; antibiotic use and resistance; gram negative; gram positive; pneumonia opportunistic infection; multidrug resistance (MDR); medical education; infection prevention control

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Use in the Communities—2nd Edition

edited by

Timo Juhani Lajunen

and

Mark Sullman

submission deadline 30 Sep 2025 | 7 articles | Viewed by 7770 | Submission Open

Keywords: antibiotic use; community; behavior; socioeconomic factors; culture; values

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Clinical Pharmacokinetics, Pharmacodynamics, and/or TDM of Antimicrobial Agents

edited by

Yukihiro Hamada

submission deadline 30 Sep 2025 | 5 articles | Viewed by 6680 | Submission Open

Keywords: pharmacokinetics/pharmacodynamics; therapeutic drug monitoring; antimicrobial resistant; AI; antimicrobial stewardship

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)

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