Special Issues

Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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From Detection to Treatment: Navigating Urinary Tract Infections with Antibiotics
edited by
submission deadline 31 Jul 2026 | 4 articles | Viewed by 24047 | Submission Open
Advancing and Standardising Antimicrobial Susceptibility and Resistance Detection Methodology
edited by
submission deadline 31 Jul 2026 | 11 articles | Viewed by 18036 | Submission Open
Keywords: antimicrobial susceptibility testing; resistance screening; rapid diagnostics; clinical; veterinary; environmental; validation
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Advancing the Discovery and Development of New Antibiotics through Drug Repurposing
edited by Songping Huang
submission deadline 31 Jul 2026 | 7 articles | Viewed by 17085 | Submission Open
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antibiotic Resistance in Wastewater Treatment Plants
edited by Qingbin Yuan
submission deadline 31 Jul 2026 | 7 articles | Viewed by 14395 | Submission Open
Keywords: antibiotic resistance genes; wastewater treatment; one health; distribution and removal of ARGs; horizontal gene transfer
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Multitalented Synthetic Antimicrobial Compounds: From Design to Effect submission deadline 31 Jul 2026 | 6 articles | Viewed by 13901 | Submission Open
Keywords: antimicrobial resistance; antibiotic development; the design of antimicrobial compounds; the synthesis of antimicrobial compounds; medicinal chemistry; bioorganic chemistry; antimicrobial properties; the mechanisms of antimicrobial activity; bioinorganic
(This special issue belongs to the Section Novel Antimicrobial Agents)
Natural Peptides to Combat Conventional Antibiotic Resistance submission deadline 31 Jul 2026 | 3 articles | Viewed by 13109 | Submission Open
Keywords: antimicrobial peptide; peptide modification; antibiotic resistance; structure– activity relationship; membrane selectivity; resistant strains
(This special issue belongs to the Section Antimicrobial Peptides)
The Antimicrobial Resistance in the Food Chain
edited by
submission deadline 31 Jul 2026 | 5 articles | Viewed by 12677 | Submission Open
Keywords: food safety; foodborne pathogens; pathways of antimicrobial resistance; antibiotic resistance; phenotypic analyses; molecular analyses; regulatory guidelines; food chemistry
Global Strategies for Antimicrobial Surveillance: Country, Regional and Global Perspectives
edited by and Gabriel Levy-Hara
submission deadline 31 Jul 2026 | 7 articles | Viewed by 11692 | Submission Open
Keywords: antimicrobial; stewardship; resistance; consumption; use
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Clostridioides difficile Infection, 3rd Edition
edited by
submission deadline 31 Jul 2026 | 4 articles | Viewed by 8405 | Submission Open
Keywords: Clostridioides difficile; Clostridioides difficile infection recurrence; antimicrobial use; host and microbiota interaction; CDI
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Biofilm-Associated Oral Diseases: Advances in Diagnosis and Challenges in Treatment
edited by and Cher Farrugia
submission deadline 31 Jul 2026 | 4 articles | Viewed by 8095 | Submission Open
Keywords: oral diseases; oral biofilms; host– biofilm interactions; novel antimicrobial strategies; molecular dynamics
(This special issue belongs to the Section Antibiofilm Strategies)
Neonatal Infection: Antibiotics for Prevention and Treatment
edited by Cinzia Auriti and Maria Paola Ronchetti
submission deadline 31 Jul 2026 | 6 articles | Viewed by 7882 | Submission Open
Keywords: neonatal infections; neonatal sepsis; sepsis definition; antibiotics in newborns; antibiotic stewardship; sepsis biomarkers; sepsis diagnosis in newborns; epidemiology of neonatal infections; fungal invasive infections
Innovations in Plant-Based Antibiotic and Antiviral Agents submission deadline 31 Jul 2026 | 3 articles | Viewed by 7507 | Submission Open
Keywords: secondary metabolites; phytochemicals; botanicals; analytical methods; toxicity
(This special issue belongs to the Section Plant-Derived Antibiotics)
Antifungal Strategies: Epidemiological Approaches, Mechanisms and Resistance in Fungal Pathogens submission deadline 31 Jul 2026 | 3 articles | Viewed by 7083 | Submission Open
Keywords: antifungal strategies; epidemiology; antifungal resistance; antifungal mechanisms; resistance genes
(This special issue belongs to the Section Fungi and Their Metabolites)
Diagnostics and Antibiotic Therapy in Bone and Joint Infections
edited by Sebastian Meller and Stavros Goumenos
submission deadline 31 Jul 2026 | 6 articles | Viewed by 5781 | Submission Open
Keywords: bone and joint infections; osteomyelitis; implant-related infections; diagnostics; antimicrobials; antibiotic therapy; PJI management; surgical site antisepsis; local antibiotic therapy; diagnostic biomarkers; multidisciplinary infection management; outcome analysis after musculoskeletal infection
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Antimicrobial Resistance Genes: Spread and Evolution, 2nd Edition
edited by
submission deadline 31 Jul 2026 | 4 articles | Viewed by 5014 | Submission Open
Keywords: microbes; antimicrobial resistance; resistance genes; gene flow; evolution
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Secondary Metabolites from Natural Sources: Mechanisms of Antimicrobial Action and Therapeutic Potential submission deadline 31 Jul 2026 | 2 articles | Viewed by 4797 | Submission Open
Keywords: secondary metabolites; bioactive compounds
(This special issue belongs to the Section Plant-Derived Antibiotics)
Gram-Negative Infections in Humans and Companion Animals: A Global Threat
edited by
submission deadline 31 Jul 2026 | 2 articles | Viewed by 3987 | Submission Open
Keywords: antimicrobial resistance; Gram-negative infections; humans; companion animals; essential oils; nanoparticles; pro-biotics; antimicrobial peptides; genomics; metagenomics
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Phage Therapy and Antimicrobial Innovation
edited by Ronen Hazan, and Amit Rimon
submission deadline 31 Jul 2026 | 3 articles | Viewed by 3493 | Submission Open
Keywords: antimicrobial resistance (AMR); antimicrobial innovation; phage therapy; phage engineering; synergistic strategies; chronic infections; biofilm; clinical phage microbiology; personalized medicine
(This special issue belongs to the Section Bacteriophages)
Advances in Antimicrobial Compounds: Exploring Natural, Synthetic, and Repositioned Drugs
edited by and Alexia Barbarossa
submission deadline 31 Jul 2026 | 2 articles | Viewed by 3315 | Submission Open
Keywords: antimicrobial compounds; natural products; synthetic agents; drug repositioning; antimicrobial resistance; synergistic approaches; mechanisms of action; drug development
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Evidence-Based Antibiotic Protocols and Digital Innovation in Oral Infection Management: Optimizing Use Through Teledentistry and Modern Diagnostics
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 3200 | Submission Open
Keywords: antibiotics; dental infections; oral infections; antibacterial resistance; telemedicine; teledentistry; antimicrobial management; AI-related
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Repositioning Drugs as a Strategy to Combat Infections submission deadline 31 Jul 2026 | 1 articles | Viewed by 3130 | Submission Open
Keywords: repositioning drugs; efflux pump inhibitors; resistant microorganisms; microbial biofilm; antibacterial resistance; antifungal potential
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Pharmacist-Led Management of Antimicrobial Treatment
edited by and Lovre Zekan
submission deadline 31 Jul 2026 | 2 articles | Viewed by 2982 | Submission Open
Keywords: antimicrobial stewardship; community pharmacy; antibiotic resistance; antimicrobial use optimisation; pharmacist intervention; antibiotic prescribing; infectious diseases
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Risks and Current Knowledge of Antimicrobial Resistance in Companion Animals submission deadline 31 Jul 2026 | 2 articles | Viewed by 2532 | Submission Open
Keywords: antimicrobial resistance; companion animals; dogs; cats; clinically important antibiotics; One Health; reverse zoonosis; zoonosis; AMR epidemiology
(This special issue belongs to the Section Antibiotics in Animal Health)
Antimicrobial Biomaterials for Dentistry submission deadline 31 Jul 2026 | 2 articles | Viewed by 2442 | Submission Open
Keywords: antimicrobials; dentistry; microorganisms; biomaterials; caries risk; oral environment; epidemiology
Epidemiology of Antimicrobial-Resistant Pathogens in Animals: A One Health Perspective submission deadline 31 Jul 2026 | 3 articles | Viewed by 2189 | Submission Open
Keywords: antimicrobial resistance (AMR); veterinary epidemiology; one health; zoonotic pathogens; surveillance systems; molecular epidemiology; resistance mechanisms
(This special issue belongs to the Section Antibiotics in Animal Health)
A Public Health Lens on Antibiotic Use: From Prescription to Resistance for ENT Infections submission deadline 31 Jul 2026 | 1 articles | Viewed by 1410 | Submission Open
Keywords: antibiotic resistance; ENT infections; public health; prescribing practices; overuse of antibiotics; diagnostic stewardship; patient education; otolaryngology; infection control
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobial Treatment and Antibiotic Use in Ophthalmology
edited by
submission deadline 31 Jul 2026 | 2 articles | Viewed by 1189 | Submission Open
Keywords: keratitis; conjunctivitis; antibiotics and combinations; antibiotic stewardship; antibiotic resistance; new therapies
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
From Nature to Laboratory Advances in Bioinspired Antimicrobial Drug Discovery submission deadline 31 Jul 2026 | 1 articles | Viewed by 1105 | Submission Open
Keywords: bioinspired antimicrobials; natural compounds; antimicrobial peptides; phytochemicals; peptidomimetics; hybrid conjugates; drug discovery; multidrug-resistant bacteria; controlled release; nanocarriers; structure– activity relationship; translational applications
(This special issue belongs to the Section Plant-Derived Antibiotics)
Alternative Approaches to Treating Antimicrobial Resistant Infections, 4th Edition submission deadline 31 Jul 2026 | 1 articles | Viewed by 1031 | Submission Open
Keywords: repurposing; anti-infectives; host-targeted therapies; bacteriophages; predatory bacteria; bacteriocins; antimicrobial peptides; nanoparticles; natural compounds; immunotherapy; probiotics; antibiotics
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Foodborne Pathogens: The Rise of Virulence and Antimicrobial Resistance submission deadline 31 Jul 2026 | Viewed by 558 | Submission Open
Keywords: foodborne pathogens; antimicrobial resistance; virulence factors; food chain; antibiotic overuse; public health; food safety; zoonotic diseases; one health
Honey: Antimicrobial and Anti-Infective Function, 2nd Edition submission deadline 31 Jul 2026 | Viewed by 387 | Submission Open
Keywords: antimicrobial activity; biofilms; infections; clinical applications; honey
(This special issue belongs to the Section Novel Antimicrobial Agents)
Biofilms and Implantable Device-Related Infections submission deadline 31 Jul 2026 | Viewed by 386 | Submission Open
Keywords: biofilm formation; implant-associated infections; medical devices; antimicrobial resistance; infection prevention
Sustainable Innovation in Antibiotic Adjuvants: Developing Strategies to Overcome Antibiotic Resistance and Biofilm Infections submission deadline 31 Jul 2026 | Viewed by 367 | Submission Open
Keywords: adjuvants; antibiotic resistance; biofilms; drug development; green chemistry; natural products; synergistic interactions
(This special issue belongs to the Section Biosynthesis and Combinatorial Approaches in Antimicrobial Discovery)
Dermatology and Wound Care: Antibiotics, Antimicrobial Therapy, Stewardship, and Resistance
edited by
submission deadline 31 Jul 2026 | Viewed by 276 | Submission Open
Keywords: dermatology; wound care; antibiotics; antimicrobials; antimicrobial resistance; antimicrobial stewardship; epidemiology; antimicrobial dressings
Pharmacokinetics and Pharmacodynamics of Antimicrobials in Pediatric Patients
edited by
submission deadline 31 Jul 2026 | Viewed by 268 | Submission Open
Keywords: antimicrobials; pediatric patients; neonates; therapeutic drug monitoring (TDM); pharmacokinetic/pharmacodynamic (PK/PD) studies; extracorporeal procedures; PK model-informed studies
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Translational Animal Models for Unraveling the Mechanisms of Action of Antimicrobial Peptides and Novel Antibiotics submission deadline 31 Jul 2026 | Viewed by 259 | Submission Open
Keywords: antimicrobial resistance (AMR); translational research; animal models; preclinical studies; antimicrobial peptides (AMPs); novel antibiotics; pharmacokinetics/pharmacodynamics (PK/PD); in vivo efficacy; infection models; biofilm
(This special issue belongs to the Section Antimicrobial Peptides)
Cystic Fibrosis: Diagnosis and Antimicrobial Therapy in the CFTR Modulator Era
edited by Guergana Petrova
submission deadline 31 Jul 2026 | Viewed by 190 | Submission Open
Keywords: cystic fibrosis; bronchiectasis; advanced lung disease; Pseudomonas aeruginosa; glucose non-fermenting Gram negative bacteria; inhaled antibiotics; mchronic infection; biofilm; sweat test; CFTR-functional testing; genetics for cystic fibrosis
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Machine Learning for Antimicrobial Resistance Prediction, 2nd Edition
edited by
submission deadline 10 Aug 2026 | 2 articles | Viewed by 8012 | Submission Open
Keywords: antimicrobial resistance prediction; artificial intelligence; machine learning; infectious diseases
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Antimicrobial Activity of Plants Against Emerging or Drug-Resistant Human Pathogens submission deadline 15 Aug 2026 | 8 articles | Viewed by 26735 | Submission Open
Keywords: anti-infective agents; antimicrobial activity; human pathogens; medicinal plants; natural products; phytodrugs
(This special issue belongs to the Section Plant-Derived Antibiotics)
Urinary Tract Infections and Antibiotic Intervention, 2nd Edition
edited by
submission deadline 20 Aug 2026 | 3 articles | Viewed by 5399 | Submission Open
Keywords: UTI; antibiotic; microbiome; PCR; next-generation sequencing; urine culture; enhanced quantitative urine cultures; urinary sepsis
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Clinical Pharmacokinetics, Pharmacodynamics, and/or TDM of Antimicrobial Agents
edited by
submission deadline 31 Aug 2026 | 7 articles | Viewed by 23362 | Submission Open
Keywords: pharmacokinetics/pharmacodynamics; therapeutic drug monitoring; antimicrobial resistant; AI; antimicrobial stewardship
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Antimicrobial Properties of Essential Oils: Activities, Mechanisms, Applications, and Therapeutic Potential
edited by , and Matteo Radice
submission deadline 31 Aug 2026 | 3 articles | Viewed by 16801 | Submission Open
Keywords: antibiotics; antibacterial; antifungal; antiviral; ethnopharmacology; multidrug resistance; natural products; resistant strains; volatile secondary metabolites; volatile compounds
(This special issue belongs to the Section Plant-Derived Antibiotics)
Companion Animals: Antimicrobial Resistance in Bacterial and Fungal Pathogens Associated with Skin and Ear Infections submission deadline 31 Aug 2026 | 6 articles | Viewed by 16379 | Submission Open
Keywords: dermatophytes; Candida; companion animals; drug susceptibility; Malassezia; mechanisms of resistance; molecular detection; Pseudomonas; Staphylococcus; One Health; MDR; veterinary
(This special issue belongs to the Section Antibiotics in Animal Health)
Antimicrobial Resistance from a One Health Perspective submission deadline 31 Aug 2026 | 3 articles | Viewed by 12204 | Submission Open
Keywords: antimicrobial resistance mechanisms; bacterial virulence; clonal diversity; molecular epidemiology; antibiotic use; infectious diseases; One Health
Rational Use of Antibiotics in Veterinary Medicine
edited by
submission deadline 31 Aug 2026 | 2 articles | Viewed by 12187 | Submission Open
Keywords: good manufacturing practice (GMP) in antibiotic production; research and systems in antibiotic quality control; consequences of improper antibiotic use; antibiotic stewardship programs; antibiotic resistance management
(This special issue belongs to the Section Antibiotics in Animal Health)
Superbugs Unleashed: Global Challenges and Solutions for Extensively Drug-Resistant and Pan-Drug-Resistant Pathogens submission deadline 31 Aug 2026 | 3 articles | Viewed by 9201 | Submission Open
Keywords: antimicrobial resistance; extensively drug-resistant pathogens; pan-drug-resistant bacteria; multidrug-resistant organisms (MDROs); infectious disease control; antibiotic stewardship; novel antimicrobials; rapid diagnostics; global health threats
Antibiotic Surveillance and Rational Use in Special Populations: Enhancing Stewardship for Vulnerable Groups submission deadline 31 Aug 2026 | 5 articles | Viewed by 8296 | Submission Open
Keywords: antibiotic stewardship; surveillance systems; special populations; rational use of antibiotics; infectious disease management
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Pharmacologic Management of MDR Respiratory and Bacteraemic Infections
edited by and Konstantinos D. Mantzarlis
submission deadline 31 Aug 2026 | 5 articles | Viewed by 7565 | Submission Open
Keywords: pneumonia; bacteraemia; intensive care; MDR infections; antibiotics
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Multi-Drug Resistant Gram-Negative Infections: Molecular Epidemiology, Microbiological Diagnosis, and Antimicrobial Treatment, 2nd Edition
edited by
submission deadline 31 Aug 2026 | 5 articles | Viewed by 5502 | Submission Open
Keywords: pharmacodynamics/pharmacokinetics (PK/PD); enterobacterales; carbapenemase; novel molecules; antimicrobial resistance
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Evaluation of Emerging Antimicrobials, 2nd Edition submission deadline 31 Aug 2026 | 2 articles | Viewed by 5068 | Submission Open
Keywords: antibacterials; antibiotics; antifungals; antimicrobial agents; antimicrobial resistance; antivirals; bacterial resistance; infections; multidrug resistance; pathogens
(This special issue belongs to the Section Novel Antimicrobial Agents)
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