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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antimicrobial and Anti-Inflammatory Activity of Bioactive Compounds Extracted from Plants, 2nd Edition

edited by

Juliana Garcia

and

Irene Gouvinhas

submission deadline 30 Nov 2025 | Viewed by 92 | Submission Open

Keywords: plants; phytochemicals; bioactive compounds; biological properties; natural products

(This special issue belongs to the Section Plant-Derived Antibiotics)

Biosynthesis, Antimicrobial Activity, and Therapeutics Development of Novel Peptides

edited by

Jiajun Wang

submission deadline 30 Nov 2025 | Viewed by 90 | Submission Open

Keywords: peptide biosynthesis; novel antimicrobial peptides; antibiotic resistance; improvement of biological stability; optimization of drug delivery systems; immune regulation; AI-driven peptide design; innovation in the field of biomedicine

(This special issue belongs to the Section Antimicrobial Peptides)

Sustainable Innovation in Antibiotic Adjuvants: Developing Strategies to Overcome Antibiotic Resistance and Biofilm Infections

edited by

Anabela Borges

and

Ana C. Afonso

submission deadline 30 Nov 2025 | Viewed by 85 | Submission Open

Keywords: adjuvants; antibiotic resistance; biofilms; drug development; green chemistry; natural products; synergistic interactions

(This special issue belongs to the Section Biosynthesis and Combinatorial Approaches in Antimicrobial Discovery)

Plant-Based Strategies for the Removal and Degradation of Antibiotics from the Environment

edited by

Giancarlo Angeles Flores

and

Paola Angelini

submission deadline 30 Nov 2025 | Viewed by 82 | Submission Open

Keywords: antibiotics; ARGs; phytoremediation; rhizosphere; plant– microbe interactions; biodegradation; detoxification; environmental pollution; resistance mitigation; sustainable remediation

Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 3rd Edition

edited by

Juan Manuel Vázquez-Lago

Ana Estany-Gestal

and

Angel Salgado-Barreira

submission deadline 30 Nov 2025 | Viewed by 78 | Submission Open

Keywords: epidemiology; social behavior; antibiotic resistance; social factors; attitudes; knowledge; practice; qualitative research; public health interventions; antibiotic prescription; community care

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Risks and Current Knowledge of Antimicrobial Resistance in Companion Animals

edited by

Djamel Drider

and

Raffaele Scarpellini

submission deadline 30 Nov 2025 | Viewed by 77 | Submission Open

Keywords: antimicrobial resistance; companion animals; dogs; cats; clinically important antibiotics; One Health; reverse zoonosis; zoonosis; AMR epidemiology

(This special issue belongs to the Section Antibiotics in Animal Health)

The Use of Systemic and Topical Antibiotics in Dentistry: Challenges and Future Perspectives

edited by

Sigrun Eick

submission deadline 30 Nov 2025 | Viewed by 72 | Submission Open

Keywords: antibiotics; apical abscess; apical periodontitis; endodontic infection; periapical disease; mouth diseases; topical antibiotics; antimicrobial approaches

Advances in Streptococcus spp. Research: Pathogenicity, Resistance, and Clinical Implications

edited by

Prescilla Emy Nagao

and

Louisy Sanches Dos Santos

submission deadline 30 Nov 2025 | Viewed by 65 | Submission Open

Keywords: Streptococcus; Corynebacterium; epidemiology; virulence; antimicrobial resistance

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Resistance and Antimicrobial Stewardship in Veterinary Medicine

edited by Tiana Florea,

Ilie Stelian

and

Degi Janos

submission deadline 30 Nov 2025 | Viewed by 64 | Submission Open

Keywords: antimicrobial stewardship; antibiotics; animals; sustainability; drugs; antimicrobial resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Small Intestinal Bacterial Overgrowth and Antimicrobials

edited by

Mislav Radić

and

Andrej Belančić

submission deadline 30 Nov 2025 | Viewed by 58 | Submission Open

Keywords: small intestine bacterial overgrowth; antibiotics; probiotics; gut microbiome

(This special issue belongs to the Section Novel Antimicrobial Agents)

The Interventions to Prevent and Reduce Healthcare-Associated Infection

edited by Nasia Safdar

submission deadline 30 Nov 2025 | Viewed by 46 | Submission Open

Keywords: infection; resistance; methicillin-resistant Staphylococcus aureus; vancomycin resistant enterococcus; Clostridioides difficile infection

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Surveillance and Molecular Diagnosis of Antimicrobial-Resistant Pathogens: From Laboratory to Clinical Practice

edited by Neena Kanwar

submission deadline 5 Dec 2025 | Viewed by 60 | Submission Open

Keywords: clinical microbiology; molecular diagnostics; infectious disease epidemiology; antimicrobial susceptibility; microbial culture

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Urinary Tract Infections and Antibiotic Intervention, 2nd Edition

edited by

Majid Mirzazadeh

submission deadline 10 Dec 2025 | Viewed by 277 | Submission Open

Keywords: UTI; antibiotic; microbiome; PCR; next-generation sequencing; urine culture; enhanced quantitative urine cultures; urinary sepsis

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

The Spread of Antibiotic Resistance in Natural Environments

edited by

Daniel Gyamfi Amoako

submission deadline 15 Dec 2025 | 3 articles | Viewed by 9020 | Submission Open

Keywords: antibiotic resistance dissemination; antibiotic pollution; environmental adaptation; mobile genetic elements; ecological impact; environmental microbiome; resistance gene transfer; resistance hotspot; genomic landscape; One Health approach; emerging contaminants; bioinformatics in environmental genomics

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Resistance and Environmental Health, 2nd Edition

edited by

Akebe Luther King Abia

submission deadline 15 Dec 2025 | 1 articles | Viewed by 1949 | Submission Open

Keywords: public health; environmental health; antibiotic resistance; environmental resistome; antibiotic-resistant bacteria; whole-genome sequencing; metagenomics; climate change and AMR; AMR models and One Health

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Challenges of Antibiotic Resistance: Biofilms and Anti-Biofilm Agents

edited by

María Melissa Gutiérrez-Pacheco

and

Luis Alberto Ortega-Ramirez

submission deadline 20 Dec 2025 | Viewed by 378 | Submission Open

Keywords: antibiotic resistance; biofilms; quorum sensing; virulence factors; resistance mechanisms; antibiofilm agents; natural compounds; synthetic drugs

(This special issue belongs to the Section Antibiofilm Strategies)

Antibiotic Surveillance and Rational Use in Special Populations: Enhancing Stewardship for Vulnerable Groups

edited by

Phumzile P Skosana

and

Filippo Mariano

submission deadline 20 Dec 2025 | Viewed by 125 | Submission Open

Keywords: antibiotic stewardship; surveillance systems; special populations; rational use of antibiotics; infectious disease management

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Environmental Risk and Antibiotic Resistance in Hospital-Acquired Infections

edited by

Catherine Neuwirth

submission deadline 20 Dec 2025 | Viewed by 44 | Submission Open

Keywords: nosocomial outbreak; environmental reservoir; investigation; corrective actions; short- and long-term outcomes

Phage Applications from Diagnostics to Treatment of Bacterial Infections in a One Health World

edited by

Mariagrazia Di Luca

and

Goran Vukotic

submission deadline 31 Dec 2025 | 8 articles | Viewed by 24695 | Submission Open

Keywords: phage therapy; antibiotic resistance; bacteriophages; regulatory framework; veterinary medicine; agriculture treatment; aquaculture

(This special issue belongs to the Section Bacteriophages)

Epidemiology and Mechanism of Bacterial Resistance to Antibiotics

edited by

Gabriela Loredana Popa

and

Mircea Ioan Popa

submission deadline 31 Dec 2025 | 10 articles | Viewed by 21317 | Submission Open

Keywords: multi-drug resistant (MDR); classic and molecular epidemiology; plasmids; resistance gene

Bacterial Detection, Identification, and Antimicrobial Susceptibility Testing

edited by

Gabriele Bianco

submission deadline 31 Dec 2025 | 7 articles | Viewed by 19998 | Submission Open

Keywords: identification methods; rapid diagnostics; MALDI-TOF MS; molecular testing; rapid antimicrobial susceptibility testing; antimicrobial susceptibility; synergy testing; β -lactam/β -lactamase inhibitor; fosfomycin; colistin

Antibiotic Resistance: A One-Health Approach, 2nd Edition

edited by

Piera Anna Martino

submission deadline 31 Dec 2025 | 8 articles | Viewed by 17975 | Submission Open

Keywords: antibiotic-resistance; One Health; virulence factors; genomics; novel natural molecules; antimicrobial stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Natural Peptides from Arthropods, Amphibians, and Reptiles to Combat Conventional Antibiotic Resistance

edited by

Christopher Shaw

Tianbao Chen

and

Lei Wang

submission deadline 31 Dec 2025 | 3 articles | Viewed by 10841 | Submission Open

Keywords: antimicrobial peptide; peptide modification; antibiotic resistance; structure– activity relationship; membrane selectivity; resistant strains

(This special issue belongs to the Section Antimicrobial Peptides)

Advancing the Discovery and Development of New Antibiotics through Drug Repurposing

edited by Songping Huang

submission deadline 31 Dec 2025 | 4 articles | Viewed by 9163 | Submission Open

(This special issue belongs to the Section Novel Antimicrobial Agents)

Preventing Antimicrobial Resistance in Hospitals: Infection Control and Antibiotic Use

edited by Dorota Pastuszak-Lewandoska,

Filip Bielec

and Małgorzata Brauncajs

submission deadline 31 Dec 2025 | 6 articles | Viewed by 8437 | Submission Open

Keywords: clinical antibiotic use; hospital infection control; healthcare-associated infections; resistance mitigation strategies; alternative therapies; antibiotic stewardship; molecular mechanisms of AMR; new therapeutic combinations of antibiotics; antimicrobial synergy

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Inappropriate Use of Antibiotics in Pediatrics

edited by Brian R. Lee

submission deadline 31 Dec 2025 | 3 articles | Viewed by 7484 | Submission Open

Keywords: antimicrobial stewardship; inappropriate antibiotic prescription; antimicrobial resistance; pediatrics

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Multitalented Synthetic Antimicrobial Compounds: From Design to Effect

edited by

Tsz Tin Yu

and

Maria Fernanda N. N. Carvalho

submission deadline 31 Dec 2025 | 4 articles | Viewed by 7418 | Submission Open

Keywords: antimicrobial resistance; antibiotic development; the design of antimicrobial compounds; the synthesis of antimicrobial compounds; medicinal chemistry; bioorganic chemistry; antimicrobial properties; the mechanisms of antimicrobial activity; bioinorganic

(This special issue belongs to the Section Novel Antimicrobial Agents)

Bacteriophage Therapy a Renaissance Weapon Recent Developments and Application, 2nd Edition

edited by

Aneta Skaradzińska

and

Paulina Śliwka

submission deadline 31 Dec 2025 | 5 articles | Viewed by 7182 | Submission Open

Keywords: bacteriophages; phage therapy; application of phages; antibiotic-resistance; antibacterial therapies

(This special issue belongs to the Section Bacteriophages)

Antimicrobial Activity of Plants Against Emerging or Drug-Resistant Human Pathogens

edited by

Andrés H. Uc-Cachón

and

Gloria María Molina-Salinas

submission deadline 31 Dec 2025 | 6 articles | Viewed by 5513 | Submission Open

Keywords: anti-infective agents; antimicrobial activity; human pathogens; medicinal plants; natural products; phytodrugs

(This special issue belongs to the Section Plant-Derived Antibiotics)

Molecular Characterization and Antimicrobial Resistance of Pathogens Isolated from Animals

edited by

Isabel Carvalho

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4600 | Submission Open

Keywords: antibiotic resistance; molecular biology; microbiology; genomics; multi-drug resistance; One Health; animals

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Resistance in Veterinary Science, 2nd Edition

edited by

Nahla O. Eltai

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4577 | Submission Open

Keywords: AMR; veterinary animals; farm animals; food animals; wild animals; resistance

(This special issue belongs to the Section Antibiotics in Animal Health)

Research Advances in Antimicrobial Stewardship, Residues and Resistance in Veterinary and Environmental Science

edited by Justine S. Gibson and

Ricardo J. Soares Magalhães

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3271 | Submission Open

Keywords: antimicrobial resistance (AMR); antimicrobial stewardship (AMS); antimicrobial residues (ARs); diagnostic tools and therapeutics; epidemiology; sustainable AMR mitigation; one health; veterinary sciences

(This special issue belongs to the Section Antibiotics in Animal Health)

Prevention and Antimicrobial Surveillance of Hospital-Associated Infections

edited by Theodouli Stergiopoulou

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2912 | Submission Open

Keywords: infection monitoring; surveillance program; antimicrobial surveillance; healthcare-associated infections

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

The Issue of Multidrug-Resistant Pathogens in Nosocomial Infections, 2nd Edition

edited by

Alberto Enrico Maraolo

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2584 | Submission Open

Keywords: antimicrobial resistance; MDR; XDR; DTR; nosocomial infections

Clostridioides difficile Infection, 3rd Edition

edited by

Guido Granata

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2385 | Submission Open

Keywords: Clostridioides difficile; Clostridioides difficile infection recurrence; antimicrobial use; host and microbiota interaction; CDI

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

The One Health Action Plan Against Antimicrobial Resistance

edited by

Anna Maria Spagnolo

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2380 | Submission Open

Keywords: one health approach; antimicrobial resistance; healthcare-associated infections; food contamination; environment and antibiotic resistance; surveillance; prevention and control

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Stewardship in Ambulatory Care Settings

edited by Mary Elizabeth Sexton and Sharon V. Tsay

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2052 | Submission Open

Keywords: ambulatory antimicrobial stewardship; antimicrobial resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Bans and Antimicrobial Resistance: Progress, Challenges, and Future Strategies

edited by

Abdelaziz Ed-Dra

and

Min Yue

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1655 | Submission Open

Keywords: impact of antibiotic bans; antibiotic use; antimicrobial resistance; antibiotic restrictions

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Bioactive Natural Products in Antimicrobial Resistance Management

edited by

Ljubiša Šarić

Zorica Tomičić

and

Ružica Tomičić

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1563 | Submission Open

Keywords: antimicrobials; antimicrobial resistance; bioactive natural products; novel antimicrobial agents; phytochemicals

(This special issue belongs to the Section Plant-Derived Antibiotics)

Therapy of Infectious Diseases Among Children and Adults: The Role of Antibiotics in Daily Practice

edited by

Magdalena Baymakova

and

Valeri R. Velev

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1322 | Submission Open

Keywords: аntibiotic use among children; аntibiotic use among adults; аntibiotic use among outpatients; аntibiotic use among inpatients; antibiotic resistance; improper antibiotic use; antibiotic quality control

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Repositioning Drugs as a Strategy to Combat Infections

edited by

Hélcio Silva Dos Santos

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1176 | Submission Open

Keywords: repositioning drugs; efflux pump inhibitors; resistant microorganisms; microbial biofilm; antibacterial resistance; antifungal potential

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Antibacterial Treatment in Periodontal and Endodontic Therapy, 3rd Edition

edited by

Andreas Braun

and

Felix Krause

submission deadline 31 Dec 2025 | 1 articles | Viewed by 930 | Submission Open

Keywords: periodontology; endodontology; cariology; photodynamics; laser dentistry

Biofilm-Associated Oral Diseases: Advances in Diagnosis and Challenges in Treatment

edited by

Naiera Zayed

and Cher Farrugia

submission deadline 31 Dec 2025 | 1 articles | Viewed by 747 | Submission Open

Keywords: oral diseases; oral biofilms; host– biofilm interactions; novel antimicrobial strategies; molecular dynamics

(This special issue belongs to the Section Antibiofilm Strategies)

Tackling Multidrug-Resistant Bacteria with New Antimicrobial Strategies

edited by

Vivek Keshri

and

Marc Maresca

submission deadline 31 Dec 2025 | 1 articles | Viewed by 737 | Submission Open

Keywords: multidrug-resistant (MDR); antimicrobial resistance (AMR); novel antibiotics; drug discovery; AMR surveillance; epidemiology

(This special issue belongs to the Section Novel Antimicrobial Agents)

Combatting Dental Infections: Insights into Oral Microbiota and Antibiotic Therapy

edited by

Biao Ren

and

Jaya Seneviratne

submission deadline 31 Dec 2025 | Viewed by 506 | Submission Open

Keywords: oral microbiota; dental diseases; systematic disease; antimicrobial; therapeutic strategies; oral biomaterials; oral probiotics; infectious disease; oral microecology; targets

Recent Advances in Efflux Pump Inhibitors and Their Role in Combatting Multidrug Resistance

edited by

László Orosz

and

Spengler Gabriella

submission deadline 31 Dec 2025 | Viewed by 332 | Submission Open

Keywords: multidrug resistance; multidrug efflux pump; efflux pump inhibitor (EPI); accumulation assay; efflux assay; fluorochromes; ethidium bromide; quorum sensing; biofilm

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Global Strategies for Antimicrobial Stewardship: Insights from WHO and PAHO

edited by

Gustavo Horacio Marin

and Gabriel Levy-Hara

submission deadline 31 Dec 2025 | Viewed by 292 | Submission Open

Keywords: antimicrobial; stewardship; resistance; consumption; use

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Global Perspectives on Antimicrobial Stewardship and Food Safety

edited by

Mahmoud Eltholth

submission deadline 31 Dec 2025 | Viewed by 271 | Submission Open

Keywords: antimicrobial resistance; antimicrobial use; food systems; food safety; antimicrobial stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Natural Compounds as Antimicrobial Agents, 3rd Edition

edited by

Carlos M. Franco

submission deadline 31 Dec 2025 | Viewed by 269 | Submission Open

Keywords: new natural antimicrobial compounds; antimicrobial effects; clinical applications; animal production applications; antifungal properties; antiviral properties; food applications; new formulations; antibacterial mechanisms; antifungal mechanisms; MICs; activity as disinfectants; activity against biofilms; effects on transcriptomics; combination with other antimicrobials; global microbiome changes

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibacterial Utilisation from Different Perspectives: An Effective Tool to Develop and Evaluate Antimicrobial Stewardship Interventions

edited by

Gyöngyvér Soós

and

Ria Benkő

submission deadline 31 Dec 2025 | Viewed by 264 | Submission Open

Keywords: quality of antibiotic use; scale of antibiotic use; pattern of antibiotic use; prevalence of antibiotic use; specific patient populations; safety of use; antibacterial; antivirals; antifungals; anti-TBC

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Displaying special issue 201-250 on page 5 of 8.

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