Superbugs Unleashed: Global Challenges and Solutions for Extensively Drug-Resistant and Pan-Drug-Resistant Pathogens

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: 31 January 2026 | Viewed by 40

Special Issue Editor


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Guest Editor
1. Faculty of Medicine, University of Medicine and Pharmacy “Grigore T. Popa” of Iași, 700115 Iasi, Romania
2. Clinic of Infectious Diseases, “Sf. Parascheva” Clinical Hospital of Infectious Diseases, 700116 Iasi, Romania
Interests: antibiotic resistance; urinary tract infections; carbapenem-resistant Enterobacterales; multidrug-resistant bacteria; healthcare-associated infections
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Special Issue Information

Dear Colleagues,

The global rise in extensively drug-resistant (XDR) and pan-drug-resistant (PDR) pathogens marks a critical turning point in the fight against infectious diseases. Once considered rare, these “superbugs” have now breached hospitals, communities, and even the food chain, challenging the very foundation of modern medicine. Infections that were once treatable with a short course of antibiotics now linger, complicate, and often prove fatal. As traditional antimicrobial therapies lose their efficacy, the threat to global health security grows more urgent.

This Special Issue, "Superbugs Unleashed: Global Challenges and Solutions for Extensively Drug-Resistant and Pan-Drug-Resistant Pathogens", collates cutting-edge research, policy perspectives, and clinical strategies aimed at confronting one of the most pressing medical crises of our time. We explore the drivers behind antimicrobial resistance, including misuse in human and veterinary medicine, and examine emerging diagnostic tools, novel therapeutic options, and global stewardship efforts.

By fostering interdisciplinary collaboration and innovation, we aim to spotlight not only the scale of the challenge but also the resilience and ingenuity of global health responses.

This Special Issue welcomes all submissions related to the epidemiology, diagnosis, treatment, surveillance, and prevention of infections caused by drug-resistant pathogens, including original research articles, reviews, and opinion papers.

Dr. Ionela-Larisa Miftode
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance
  • extensively drug-resistant pathogens
  • pan-drug-resistant bacteria
  • multidrug-resistant organisms (MDROs)
  • infectious disease control
  • antibiotic stewardship
  • novel antimicrobials
  • rapid diagnostics
  • global health threats

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Published Papers

This special issue is now open for submission.
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