Multitalented Synthetic Antimicrobial Compounds: From Design to Effect

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 111

Special Issue Editors

School of Chemistry, University of New South Wales (UNSW Sydney), Sydney, NSW 2052, Australia
Interests: medicinal chemistry; antimicrobials; peptidomimetics; quorum sensing; Antibiofilm
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Guest Editor
Instituto Superior Técnico, University of Lisbon, 1049-001 Lisbon, Portugal
Interests: synthesis of coordination and organic compounds; medicinal chemistry; drugs; bioactive compounds; redox properties
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The rapid emergence of antimicrobial resistance poses a serious threat to public health. The misuse and overuse of antibiotics has contributed to the development of antimicrobial resistance, rendering antibiotics ineffective for treating multi-drug-resistant bacterial and fungal infections. In addition, the lack of innovation in the development of novel therapeutic strategies in the last few decades has undermined efforts to circumvent multi-drug-resistant infections. Hence, there is an urgent need to design and develop new classes of antimicrobial compounds, particularly those with broad antibacterial and/or fungal activity.

This Special Issue will compile up-to-date research on novel antimicrobial compounds. Topics to be covered in this Special Issue include, but are not limited to, the design and synthesis of antimicrobial compounds, the development of synthetic analogues of natural products with antimicrobial activity, the in vitro and/or in vivo antimicrobial evaluation of synthetic compounds, and the mechanisms of action of novel antimicrobial compounds.

Prospective authors are invited to submit their research findings as full articles, communications, or reviews related to this topic.

Dr. Tsz Tin Yu
Dr. Maria Fernanda N. N. Carvalho
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • antimicrobial resistance
  • antibiotic development
  • the design of antimicrobial compounds
  • the synthesis of antimicrobial compounds
  • medicinal chemistry
  • bioorganic chemistry
  • antimicrobial properties
  • the mechanisms of antimicrobial activity
  • bioinorganic

Published Papers

This special issue is now open for submission.
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