Gram-Negative Infections in Humans and Companion Animals: A Global Threat
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "The Global Need for Effective Antibiotics".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 56
Special Issue Editor
Interests: antibiotic resistance; alternative to antibiotics; biofilm formation; nanoparticles; essential oils; whole genome sequencing; metagenomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antibiotic resistance constitutes a significant worldwide health threat, necessitating a cooperative One Health strategy that requires human, animal, and environmental health initiatives to tackle its intricate interrelations. In this scenario, Gram-negative infections have garnered global attention due to the alarming therapeutic failures caused by antimicrobial resistance. Some of these pathogens, like Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species, are considered major threats due to multidrug-resistant clones, presenting a significant challenge in clinical practice. Multidrug resistance ranks among the foremost dangers to worldwide public health, typically resulting from excessive drug consumption or prescription, improper use of antimicrobials, and poor-quality pharmaceuticals. Comprehending the resistance mechanisms of these bacteria is essential for the creation of innovative antimicrobial drugs or alternative strategies to address these public health issues. Moreover, the similarity of prescribed antimicrobials in human and veterinary medicines, coupled with the close interaction between companion animals and humans, heightens the risk of antibiotic-resistant transmission. This facilitates the potential for interspecies transmission of resistant microorganisms; however, the existing knowledge of this important aspect is limited and not fully characterized.
This Special Issue of Antibiotics solicits reviews, research articles, and brief communications that will enhance our current understanding of Gram-negative-derived infections in humans and companion animals, describing not only the antimicrobial resistance profiles using common techniques (both phenotypic or molecular), but also investigating the role of essential oils, metal nanoparticles, probiotics, antimicrobial peptides, bacteriocins, and bacteriophages as alternatives to antibiotic treatments.
Dr. Gabriele Meroni
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antimicrobial resistance
- Gram-negative infections
- humans
- companion animals
- essential oils
- nanoparticles
- pro-biotics
- antimicrobial peptides
- genomics
- metagenomics
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