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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Antimicrobial Therapies for Oral Infections: From Biofilm Disruption to Clinical Applications

edited by

Cláudia Helena Silva-Lovato

and

Adriana Barbosa Ribeiro

submission deadline 31 Jan 2026 | Viewed by 69 | Submission Open

Keywords: oral infections; microbial biofilm; antimicrobial therapies

(This special issue belongs to the Section Antibiofilm Strategies)

A Themed Issue in Honor of Professor Aditya Gupta—Outstanding Contributions to Antifungal Therapy, Dermatology and Mycology

edited by Ditte Marie Saunte and Mesbah Talukder

submission deadline 31 Jan 2026 | Viewed by 66 | Submission Open

Keywords: onychomycosis; antifungal resistance; dermatophyte infections; antifungal stewardship; Trichophyton indotineae; topical and oral antifungals; treatment algorithms; epidemiology of onychomycosis

Evidence-Based Antibiotic Protocols and Digital Innovation in Oral Infection Management: Optimizing Use Through Teledentistry and Modern Diagnostics

edited by

Manlio Santilli

submission deadline 31 Jan 2026 | Viewed by 48 | Submission Open

Keywords: antibiotics; dental infections; oral infections; antibacterial resistance; telemedicine; teledentistry; antimicrobial management; AI-related

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance in Bacterial Pathogens: Insights from Veterinary Medicine

edited by

Dimitris C. Chatzopoulos

submission deadline 31 Jan 2026 | Viewed by 43 | Submission Open

Keywords: antimicrobial resistance (AMR); veterinary medicine; One Health; animal health; zoonotic transmission; surveillance and monitoring

(This special issue belongs to the Section Antibiotics in Animal Health)

Clostridioides difficile Infection: Pathogenesis, Antibiotic Resistance, and Therapeutic Advances

edited by

Yongrong Zhang

submission deadline 31 Jan 2026 | Viewed by 32 | Submission Open

Keywords: Clostridioides difficile; infection; recurrence; antibiotic resistance; therapeutics; pathogenesis

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Mechanisms of Microbial Biofilm Resistance and New Methods for Biofilm Control

edited by

Gianmarco Mangiaterra

submission deadline 31 Jan 2026 | Viewed by 24 | Submission Open

Keywords: quorum sensing; chronic infections; antibiotic resistance; persistence; efflux pumps

(This special issue belongs to the Section Antibiofilm Strategies)

Antibiotic or Antibiotic Adjuvant Synthesis and Antimicrobial Evaluation, 2nd Edition

edited by

Jean Michel Brunel

submission deadline 31 Jan 2026 | Viewed by 22 | Submission Open

Keywords: antimicrobial agents; synergy; adjuvants; bacterial resistance

Antimicrobial Stewardship in Surgical Infection

edited by Nuno Rocha-Pereira

submission deadline 31 Jan 2026 | Viewed by 19 | Submission Open

Keywords: antimicrobial stewardship; surgical infection; surgical site infection; antimicrobial resistance; diagnostic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance (AMR) in the Food Chain: Detection Gaps and Mitigation Strategies

edited by

Joana Castro

José António Baptista Machado Soares

and

Ricardo Oliveira

submission deadline 31 Jan 2026 | Viewed by 19 | Submission Open

Keywords: antimicrobial resistance (AMR); foodborne pathogens; surveillance; detection methods; mitigation strategies; One Health

(This special issue belongs to the Section Antibiotics in Animal Health)

Diagnostics and Antibiotic Therapy in Bone and Joint Infections

edited by Sebastian Meller and Stavros Goumenos

submission deadline 31 Jan 2026 | Viewed by 9 | Submission Open

Keywords: bone and joint infections; osteomyelitis; implant-related infections; diagnostics; antimicrobials; antibiotic therapy; PJI management; surgical site antisepsis; local antibiotic therapy; diagnostic biomarkers; multidisciplinary infection management; outcome analysis after musculoskeletal infection

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

A Themed Issue in Honor of Prof. Jae-hyuk Yu—Antimicrobial Resistance in the Foodborne Pathogens

edited by

Hee-Soo Park

and Ahmad Alshannaq

submission deadline 1 Feb 2026 | Viewed by 101 | Submission Open

Keywords: foodborne pathogens; antimicrobial resistance (AMR); food safety; antimicrobial preservation; food additives; antimicrobial resistance mechanisms

Livestock Antibiotic Use and Resistance

edited by Valentina Monistero,

Paola Cremonesi

Gloria Gioia

and Valerio Bronzo

submission deadline 15 Feb 2026 | 7 articles | Viewed by 6971 | Submission Open

Keywords: farm; livestock; antibiotic; antimicrobial resistance; One Health; multidrug-resistant; methicillin-resistant; extended-spectrum beta-lactamase; carbapenemase; superbug

(This special issue belongs to the Section Antibiotics in Animal Health)

Omics Approaches, Including Culturomics, for Assessing Antimicrobial Resistance in Bacterial Communities

edited by

Samantha Flores-Treviño

submission deadline 15 Feb 2026 | Viewed by 68 | Submission Open

Keywords: omics; culturomics; MALDI-TOF; antimicrobial resistance; gut microbiota

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Innovations in Antibacterial Agents: Combating Resistance, Improving Efficacy and Exploring New Mechanisms

edited by

Rok Frlan

and

Martina Hrast

submission deadline 20 Feb 2026 | 3 articles | Viewed by 6276 | Submission Open

Keywords: drug design; synthesis of novel antibacterial agents; computational chemistry; repurposing of drugs; novel antibacterial mechanisms

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Resistance in Biofilm-Associated Infections

edited by

Fazlurrahman Khan

Nazia Tabassum

and

Young-Mog Kim

submission deadline 25 Feb 2026 | 3 articles | Viewed by 3470 | Submission Open

Keywords: biofilms; antimicrobial resistance; chronic infections; biofilm matrix; virulence factors; antibiotic efficacy; pathogen persistence; biofilm formation; medical implants; quorum sensing

(This special issue belongs to the Section Antibiofilm Strategies)

Nanoparticles as Antibacterial/Antibiofilm Agents

edited by

J. Scott VanEpps

submission deadline 28 Feb 2026 | 7 articles | Viewed by 23114 | Submission Open

Keywords: nanoparticles; antibacterial; biofilm; mechanism; antibiotic resistance

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Antimicrobial Resistance and Infections in Veterinary Settings

edited by Hatem Kittana and Tamara Gull

submission deadline 28 Feb 2026 | 3 articles | Viewed by 10757 | Submission Open

Keywords: veterinary medicine; antibiotics; antimicrobial resistance; infectious microorganims; food-producing animals; companion aniamls

(This special issue belongs to the Section Antibiotics in Animal Health)

Clinical Guidelines and Real Practice of Antimicrobial Pharmacotherapy

edited by

Darko Modun

submission deadline 28 Feb 2026 | 5 articles | Viewed by 9759 | Submission Open

Keywords: adverse drug reaction; patient adherence; antimicrobial resistance; clinical guidelines; clinical settings; regional factors; pharmacotherapy

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Genomic Analysis of Drug-Resistant Pathogens

edited by

Erica Diani

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5517 | Submission Open

Keywords: multi-drug resistant; mutation; bacteria; NGS; sequencing; mobile genetics elements; gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Virulence, Antimicrobial Resistance and Biofilm Production in Veterinary, Zoonotic and Food-Related Pathogens

edited by Óscar Mencía-Ares, Paula Fernández-Gómez and

Sonia Martinez

submission deadline 28 Feb 2026 | 3 articles | Viewed by 3200 | Submission Open

Keywords: animal health; antimicrobial resistance; biofilm; food-borne pathogens; microbiology; pathogenicity; public health; veterinary pathogens; virulence; zoonosis

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Stewardship and Infection Prevention in Intensive Care Unit

edited by Mihai Sava and

Majdi N. Al-Hasan

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3083 | Submission Open

Keywords: antimicrobial stewardship; infection prevention; intensive care unit (ICU); antimicrobial resistance; healthcare-associated infections; patient safety

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Genetic Mechanisms of Bacterial Survival: Antibiotic Resistance and Defense Strategies

edited by

Caio Augusto Martins Aires

and Thiago Pavoni Gomes Chagas

submission deadline 28 Feb 2026 | 1 articles | Viewed by 985 | Submission Open

Keywords: antimicrobial resistance mechanisms; disinfectant and antiseptic resistance; biofilm formation; genomic insights; horizontal gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Stewardship in the Management of Bloodstream Infections

edited by

Zoran Todorovic

Gordana Dragović

and Saša Trailović

submission deadline 28 Feb 2026 | Viewed by 242 | Submission Open

Keywords: bloodstream infections; antimicrobial drugs; immunodeficiency; sepsis; antimicrobial resistance; therapeutic drug monitoring

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Optimization of Antimicrobial Stewardship in Public Health, 2nd Edition

edited by

Aoife Fleming

and

Vito D'Andrea

submission deadline 28 Feb 2026 | Viewed by 241 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial prescribing; antimicrobial surveillance; primary care; secondary care; long-term care; penicillin allergy; pharmacy; public health; general practice; point-of-care testing; qualitative research

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Natural Extracts as Antimicrobial Agents in Infectious Disease Therapy

edited by

Francesca Mariani

submission deadline 28 Feb 2026 | Viewed by 184 | Submission Open

Keywords: medicinal plants; phytocomplexes; essential oils; intracellular bacteria; bacterial cell wall; minimal inhibitory concentration (MIC); minimal bactericidal concentration (MBC); antiadhesive properties; bacterial biofilm; minimal biofilm-inhibiting concentration (MBIC)

(This special issue belongs to the Section Plant-Derived Antibiotics)

New Advances in Antibiotic Therapy in the Gastroenterology Field

edited by

Giuseppe Guido Maria Scarlata

and Francesca Serapide

submission deadline 28 Feb 2026 | Viewed by 128 | Submission Open

Keywords: antibiotic therapy; antimicrobial resistance; gastroenterology; infectious diseases; microbiology; gut– liver axis; antimicrobial stewardship; infection control; biomarkers; diagnosis; epidemiology

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Pioneering the Microbiome—Infections, Inflammation, Inflammatory Bowel Disease and the Role of Antibiotic Therapy

edited by

Gaurav Agrawal

and

Roger Pickup

submission deadline 28 Feb 2026 | Viewed by 42 | Submission Open

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Current Advances and Innovations in Anti-Infective Agents Discovery

edited by

Valnês da Silva Rodrigues-Junior

submission deadline 28 Feb 2026 | Viewed by 34 | Submission Open

Keywords: drug development; antiviral; antibacterial; antifungal; antiparasitic

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Resistance at the Human–Animal Interface: Surveillance, Epidemiology, Modelling and Risk Assessment

edited by

Alessandro Bellato

and

Alessandro Mannelli

submission deadline 28 Feb 2026 | Viewed by 32 | Submission Open

Keywords: antimicrobial resistance (AMR); human– animal interface; One Health; surveillance; epidemiology; risk assessment; veterinary medicine; zoonotic transmission

Antimicrobial Resistance and Pharmacotherapy in the Elderly: Challenges and Innovations in Medication Management

edited by

Tiago Lima

, Ana Marta Lavrador and Ana C. Cabral

submission deadline 28 Feb 2026 | Viewed by 29 | Submission Open

Keywords: antimicrobial resistance; elderly pharmacotherapy; multidrug-resistant infections; medication management; antimicrobial stewardship; polypharmacy; geriatrics; drug& ndash; microbiota interactions

Resistance, Treatment and Prevention of ESKAPE Pathogens

edited by

Steven E. Fiester

and

William Penwell

submission deadline 28 Feb 2026 | Viewed by 27 | Submission Open

Keywords: antibiotic resistance; prevention methods; treatment strategies; ESKAPE pathogens

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Epidemiology and Pathogenomics of the Corynebacterium Genus

edited by

Vasco Azevedo

submission deadline 28 Feb 2026 | Viewed by 27 | Submission Open

Keywords: Corynebacterium; epidemiology; genomics; diagnostic; vaccine; drugs

Optimizing Antimicrobial Use: Antimicrobial Stewardship and Surveillance, 2nd Edition

edited by Jesus Ruiz-Ramos

submission deadline 28 Feb 2026 | Viewed by 14 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial cycling; antimicrobial resistance; decision support; antibiotic optimization; antibiotic therapy

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

A Themed Issue in Honor of Professor Stefan Schwarz—Antimicrobial Resistance of Bacteria of Animal Origin: Diagnostics, Monitoring, Mechanisms and Epidemiology

edited by

Igor Loncaric

and Séamus Fanning

submission deadline 1 Mar 2026 | Viewed by 166 | Submission Open

Keywords: antimicrobial resistance; animals; resistance genes; mechanism of resistance; MRSA; ESBL; staphylococci; enterobacterales

Antibiotic Resistance in Bacterial Isolates of Animal Origin

edited by

Tomasz Jarzembowski

and

Lidia Piechowicz

submission deadline 5 Mar 2026 | Viewed by 18 | Submission Open

Keywords: zoonotic infection; resistance genes; “ one health concept” ; Salmonella enterica; Campylobacter jejuni; enterohemorrhagic Escherichia coli; Enterococcus faecalis

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Activities of Bioactive Components from Honeybee Products

edited by

Otilia Bobis

Adriana Cristina Urcan

and

Claudia Pașca

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2298 | Submission Open

Keywords: bee products; antibiotics; antimicrobial activity; bioactive compounds; honey; propolis; bee pollen/beebread; royal jelly; bee venom; microbial resistance

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Resistance and Virulence in Bacterial Isolates: A Genomic Perspective from Human and Animal Sources

edited by

Sónia Ramos

and

Alexandra Nunes

submission deadline 31 Mar 2026 | 1 articles | Viewed by 750 | Submission Open

Keywords: MDRB; antimicrobial resistance; one health; mobile genetic elements; AMR; antimicrobial resistance gene

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Periodontal Bacteria and Periodontitis: Infections and Therapy

edited by Anna Skurska

submission deadline 31 Mar 2026 | 1 articles | Viewed by 369 | Submission Open

Keywords: periodontitis; infection; antibiotics; antibacterial activities

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Global Partnerships in Response to Antimicrobial Resistance: From Policy to Practice

edited by

Helena Rosado

submission deadline 31 Mar 2026 | Viewed by 172 | Submission Open

Keywords: antimicrobial resistance; antimicrobial stewardship; global health partnerships; collaboration; low- and middle-income countries; health systems strengthening; actionable implementation; AMR interventions

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Peptides in Agriculture and Food Safety

edited by

Da Teng

submission deadline 31 Mar 2026 | Viewed by 104 | Submission Open

Keywords: AI-based discovery and design; biotechnology; mechanisms of action; novel delivery systems; animal husbandry; aquaculture; plant conservation; food preservation

Antibiotic Synthesis, 2nd Edition

edited by

Naresh Kumar

and

Tsz Tin Yu

submission deadline 31 Mar 2026 | Viewed by 79 | Submission Open

Keywords: new antimicrobial compounds; dual-action antimicrobials; new antimicrobial targets; targeted delivery of antibiotics; new scaffolds for antimicrobial discovery; discovery of new antimicrobial mechanisms

(This special issue belongs to the Section Novel Antimicrobial Agents)

Surveillance and Detection of Antimicrobial Resistance: Tools and Trends

edited by

Hung-Sheng Shang

submission deadline 31 Mar 2026 | Viewed by 14 | Submission Open

Keywords: antimicrobial resistance; surveillance systems; pathogen detection; rapid diagnostics; genomic surveillance; artificial intelligence; point-of-care testing; public health strategy; molecular epidemiology; big data analytics

Evidence in Antibiotic Mastitis Therapy

edited by

Volker Krömker

and

Paolo Moroni

submission deadline 30 Apr 2026 | 1 articles | Viewed by 246 | Submission Open

Keywords: antibiotic mastitis treatment; targeted; selective; pathogens; mastitis history; new infections

(This special issue belongs to the Section Antibiotics in Animal Health)

Antibiotic Prescribing in Primary Dental Care—2nd Edition

edited by

Kristina Peros

submission deadline 30 May 2026 | Viewed by 53 | Submission Open

Keywords: primary dental care; antibiotic prescribing; rational drug prescribing; antibiotic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Optimizing Antimicrobial Therapy in NICU Settings: Strategies and Implications

edited by

Elias Iosifidis

and

Angeliki Kontou

submission deadline 31 May 2026 | 1 articles | Viewed by 1347 | Submission Open

Keywords: neonatal ICU; antimicrobial stewardship; antimicrobial resistance; neonatal sepsis; biomarkers

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Periprosthetic Joint Infection: Understanding the Epidemiology, Pathogenesis, Diagnosis and Treatment Options

edited by Saad Tarabichi, Mark J. Spangehl and Joshua S. Bingham

submission deadline 31 May 2026 | 1 articles | Viewed by 802 | Submission Open

Keywords: periprosthetic joint infection; diagnosis; epidemiology; pathogenesis; treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

New Drugs, Innovative Antimicrobial Approaches, and Optimized Dosages: Bridging Research and Clinical Practice

edited by

Jerónimo Pachón

, Rocío Álvarez-Marín and

María E. Pachón-Ibáñez

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1016 | Submission Open

Keywords: antibiotics; antivirals; pharmacokinetics and pharmacodynamics; clinical evaluation; experimental studies; new antimicrobial approaches

Diagnostics, Antibiotic Usage and Surgery Related Techniques in Prevention and Treatment of Prosthetic Joint and Implant Related Infections

edited by

Bernd Fink

and

Steffen Ruchholtz

submission deadline 30 Jun 2026 | 1 articles | Viewed by 51 | Submission Open

Keywords: periprosthetic joint infection; implant-related infection; antibiotics; spacer; diagnosis; septic revision arthroplasty; irrigation; debridement

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

New Approaches to the Treatment and Prevention of Fungal Infections

edited by