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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antimicrobial Activity of Bioactive Peptides and Their Derivatives

edited by Alexandro Rodríguez-Rojas

submission deadline 20 Jul 2025 | 6 articles | Viewed by 8515 | Submission Open

Keywords: antimicrobial resistance (AMR); global health threat; novel antimicrobial agents; bioactive peptides (AMPs); natural antimicrobial agents; broad-spectrum activity; antimicrobial activity; mechanisms of action; structure– activity relationships; AMP-based therapeutics; clinical applications of AMPs; combinatory therapy

(This special issue belongs to the Section Antimicrobial Peptides)

Plant Extracts and Natural Products for the Control of Animal Pathogens in a ONE-Health Perspective

edited by Ernesto Palma,

Roberto Bava

and Carmine Lupia

submission deadline 20 Jul 2025 | 1 articles | Viewed by 853 | Submission Open

Keywords: natural products; essential oils; hive products; colostrum; pets; livestock; drug resistances; antimicrobial resistances; sustainable pathogen control; animal health and welfare

(This special issue belongs to the Section Antibiotics in Animal Health)

Foodborne Pathogens: The Rise of Virulence and Antimicrobial Resistance

edited by

Luisa Brito

and

Acacio Salamandane

submission deadline 20 Jul 2025 | Viewed by 179 | Submission Open

Keywords: foodborne pathogens; antimicrobial resistance; virulence factors; food chain; antibiotic overuse; public health; food safety; zoonotic diseases; one health

Novel Approaches for the Treatment of Antimicrobial-Resistant Pathogens

edited by

Yosra A. Helmy

submission deadline 31 Jul 2025 | 2 articles | Viewed by 36034 | Submission Open

Keywords: antimicrobial resistance diagnosis and surveillance; antibiotic alternatives and development of novel drugs; whole-genome sequencing; gut microbiota; infectious pathogens in animals and humans

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotics and Environment − Research and Development toward the One Health Approach

edited by

Takashi Azuma

submission deadline 31 Jul 2025 | 7 articles | Viewed by 24369 | Submission Open

Keywords: antimicrobial resistance (AMR); antimicrobials; water purification plant (WTP); wastewater treatment plant (WWTP); hospital wastewater; livestock environment; aquaculture farm environment; aquatic environment

Antibiotics as Major Disruptors of Gut Microbiota

edited by

Gábor Ternák

submission deadline 31 Jul 2025 | 6 articles | Viewed by 18993 | Submission Open

Keywords: microbiome; gut flora; development of gut flora; dysbiosis; antibiotics; antibiotic classes; antibiotic consumption; gut– brain axis; short-chain fatty acids; metabolom; mediator molecules; composition of gut flora

Green Antimicrobials in Biomedical Engineering: Recent Advances Proposal

edited by

Helena Felgueiras

submission deadline 31 Jul 2025 | 6 articles | Viewed by 13303 | Submission Open

Keywords: antimicrobial agents concomitant; synergistic and additive effects surface functionalization; antimicrobial properties; biomedical therapies; bioactive molecules; green synthesis; environmentally friendly; circular economy; waste materials’ second life

(This special issue belongs to the Section Novel Antimicrobial Agents)

Alternative Approaches to Treating Antimicrobial Resistant Infections, 3rd Edition

edited by

Michal Letek

and

Volker Behrends

submission deadline 31 Jul 2025 | 5 articles | Viewed by 12914 | Submission Open

Keywords: repurposing; anti-infectives; host-targeted therapies; bacteriophages; predatory bacteria; bacteriocins; antimicrobial peptides; nanoparticles; natural compounds; immunotherapy; probiotics; antibiotics

Antibiotic Treatment on Surgical Infections

edited by

Fausto Catena

submission deadline 31 Jul 2025 | 3 articles | Viewed by 12283 | Submission Open

Keywords: surgical site; infection; emergency surgery; prevention

Genomic Analysis of Antimicrobial Drug-Resistant Bacteria

edited by

Maria Rosario Rodicio

and

Carlos Rodriguez-Lucas

submission deadline 31 Jul 2025 | 6 articles | Viewed by 11831 | Submission Open

Keywords: antimicrobial drug resistance; whole-genome sequencing; genomic epidemiology; one health; bacterial pathogens; mobile genetic elements; horizontal gene transfer; phylogenetics; evolution

(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)

Antimicrobial Resistance in the Community Setting: The Other Side of the Coin

edited by

Luigi Principe

submission deadline 31 Jul 2025 | 4 articles | Viewed by 11587 | Submission Open

Keywords: emerging resistance; multidrug resistance; emerging virulence; community setting; Staphylococcus aureus; Enterococcus spp.; Streptococcus spp.; Haemophilus spp.; Moraxella spp.; Mycobacterium spp.; Neisseria spp.; Salmonella spp.; Shigella spp.; Campylobacter spp.; anaerobes; fungi

Staphylococcal Biology and Pathogenesis

edited by Richard Proctor

submission deadline 31 Jul 2025 | 5 articles | Viewed by 10068 | Submission Open

Sepsis Management and Antibiotic Therapy

edited by

Egidia Gabriela Miftode

submission deadline 31 Jul 2025 | 6 articles | Viewed by 9893 | Submission Open

Keywords: sepsis; antibiotic therapy; infection; antimicrobial; antifungal

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Strategies for Combatting Multidrug-Resistant and Extensively Drug-Resistant Bacteria, 2nd Edition

edited by

Bożena Futoma-Kołoch

, Anna Kędziora and

Adriána Liptáková

submission deadline 31 Jul 2025 | 6 articles | Viewed by 8393 | Submission Open

Keywords: MDR bacteria; EDR bacteria; novel antimicrobial drugs; novel therapeutical approaches against MDR; novel therapeutical approaches against EDR; guidelines; personalized microbiota; bacteriophages; autovaccine therapy; antimicrobial stewardship

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Challenges and Emerging Strategies to Tackle the Global Burden of Antimicrobial Resistance

edited by

Tomislav Meštrović

submission deadline 31 Jul 2025 | 3 articles | Viewed by 8265 | Submission Open

Keywords: antimicrobial resistance (AMR); global burden of AMR; AMR in the context of public and global health; diagnostic and treatment of AMR; new approaches to AMR surveillance; antibiotic stewardship; local and global policy initiatives on AMR; prevention of AMR

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Clinical Guidelines and Real Practice of Antimicrobial Pharmacotherapy

edited by

Darko Modun

submission deadline 31 Jul 2025 | 5 articles | Viewed by 8088 | Submission Open

Keywords: adverse drug reaction; patient adherence; antimicrobial resistance; clinical guidelines; clinical settings; regional factors; pharmacotherapy

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial and Antibiofilm Activity by Natural Compounds

edited by

Galdino Andrade

Sueli F. Yamada-Ogatta

and Martha Viviana Torres Cely

submission deadline 31 Jul 2025 | 4 articles | Viewed by 6354 | Submission Open

Keywords: pathogens; human; animal; crops; antibiotic

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antibiotics Use and Stewardship in Hospitals and Outpatient Care Facilities, 2nd Edition

edited by

Islam M. Ghazi

and Ahmed El Yazbi

submission deadline 31 Jul 2025 | 4 articles | Viewed by 6224 | Submission Open

Keywords: antimicrobial stewardship; novel antibiotics; microbial resistance; optimizing treatment; pharmacokintics/pharmacodynamics

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Orthopedic Infections: Epidemiology and Antimicrobial Treatment

edited by Éric Bonnet

submission deadline 31 Jul 2025 | 4 articles | Viewed by 5816 | Submission Open

Keywords: chronic osteomyelitis; prosthetic joint infections; epidemiology; microbiology; antimicrobial treatment; treatment duration; local antibiotics

Antibacterial, Antibiofilm and Anti-virulence Activity Research of Both Natural and Synthetic Products, 2nd Edition

edited by

Eliana De Gregorio

and

Anna Esposito

submission deadline 31 Jul 2025 | 2 articles | Viewed by 5509 | Submission Open

Keywords: antimicrobial agent; antibiofilm agent; synergy between new antimicrobial products and conventional antibiotics; anti-virulence agent; mechanism of drug action; repurposing of approved drugs as antibacterial agent; biofilms; virulence factors

(This special issue belongs to the Section Plant-Derived Antibiotics)

Rational Use of Antibiotics in Veterinary Medicine

edited by

JeongWoo Kang

submission deadline 31 Jul 2025 | 2 articles | Viewed by 4988 | Submission Open

Keywords: good manufacturing practice (GMP) in antibiotic production; research and systems in antibiotic quality control; consequences of improper antibiotic use; antibiotic stewardship programs; antibiotic resistance management

(This special issue belongs to the Section Antibiotics in Animal Health)

Emerging Challenges in Food Safety: Addressing Antimicrobial Resistance, Virulence Factors, and Biofilm Formation in Food-Borne Pathogens

edited by

Liora Mihaela Colobățiu

, Marian Mihaiu and

Zorita Diaconeasa

submission deadline 31 Jul 2025 | 3 articles | Viewed by 3788 | Submission Open

Keywords: antimicrobial resistance; food-borne pathogens; food safety; virulence factors; biofilm formation; resistance genes; food production; public health; molecular epidemiology; infection control

Managing Appropriate Antibiotic Prescribing and Use in Primary Care

edited by

Ruby Biezen

submission deadline 31 Jul 2025 | 3 articles | Viewed by 3401 | Submission Open

Keywords: primary care; general practice; antimicrobial stewardship; antimicrobial resistance; infectious disease; appropriate prescribing; guidelines concordance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Pathogenic and Antibiotic-Resistant Bacteria in Gut Microbiota

edited by

Bing-Mu Hsu

submission deadline 31 Jul 2025 | 2 articles | Viewed by 3076 | Submission Open

Keywords: gut microbiota; pathogenic bacteria; antibiotic resistance; gastrointestinal tract; microbiome dynamics; host– pathogen interactions; transmission dynamics; therapeutic interventions; antibiotic stewardship; public health strategies

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Peptide Antibiotics from Microbes and Venomous Animals, 2nd Edition

edited by

Jean-Marc Sabatier

submission deadline 31 Jul 2025 | 1 articles | Viewed by 2424 | Submission Open

Keywords: peptide antibiotics; antibacterial peptide; bacteria; microbe; venomous animal; bacteriocin; venom

(This special issue belongs to the Section Antimicrobial Peptides)

Beyond Phages: Exploring Endolysins as Key Players in the Future of Antibacterial Therapeutics

edited by

Pilar García Suárez

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2243 | Submission Open

Keywords: endolysins; bacteriophages; phage therapy; antimicrobial resistance; clinical trials; regulatory framework

(This special issue belongs to the Section Bacteriophages)

Knowledge, Attitudes and Practices of Antimicrobial Resistance and Stewardship in Primary Care Setting: From Understanding to Informing Interventions

edited by

Amanj Kurdi

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2201 | Submission Open

Keywords: antimicrobial resistance; antimicrobial stewardship; primary care; knowledge; attitudes and practices; antimicrobial stewardship interventions

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance and One Health: New Solutions for an Old Problem?

edited by

David Rodríguez-Lázaro

and

José María Eiros-Bouza

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1855 | Submission Open

Keywords: antimicrobial resistance; one health; global health; surveillance; primary porduction; food safety; environment health; nosocomial infections

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

The Antibiotic Resistance and Virulence Genes of Pathogens in Aquatic and Soil Environment

edited by

Bing Li

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1835 | Submission Open

Keywords: antibiotic resistance genes (ARGs); virulence genes; pathogenic bacteria; horizontal gene transfer

Virulence, Antimicrobial Resistance and Biofilm Production in Veterinary, Zoonotic and Food-Related Pathogens

edited by Óscar Mencía-Ares, Paula Fernández-Gómez and

Sonia Martinez

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1799 | Submission Open

Keywords: animal health; antimicrobial resistance; biofilm; food-borne pathogens; microbiology; pathogenicity; public health; veterinary pathogens; virulence; zoonosis

(This special issue belongs to the Section Antibiotics in Animal Health)

The Worldwide Problem of Antifungal Resistance: From Basic to Clinic

edited by

Max Carlos Ramírez-Soto

and

Alexandro Bonifaz

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1439 | Submission Open

Keywords: antifungal agents; antifungal resistance; fungal pathogens; pharmacology; therapeutic use

Antifungal Strategies: Epidemiological Approaches, Mechanisms and Resistance in Fungal Pathogens

edited by

Erick Martinez-Herrera

Rodolfo Pinto-Almazán

and

Carmen Rodríguez-Cerdeira

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1417 | Submission Open

Keywords: antifungal strategies; epidemiology; antifungal resistance; antifungal mechanisms; resistance genes

(This special issue belongs to the Section Fungi and Their Metabolites)

Secondary Metabolites from Natural Sources: Mechanisms of Antimicrobial Action and Therapeutic Potential

edited by

Fatima Cerqueira

and

Maria Pia Ferraz

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1097 | Submission Open

Keywords: secondary metabolites; bioactive compounds

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial Resistance: Epidemiology and Implications for Veterinary Medicine

edited by

Bruno de araujo Penna

and

Eliane De Oliveira Ferreira

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1003 | Submission Open

Keywords: antimicrobial resistance; One Health; epidemiology; transmission; zoonoses

(This special issue belongs to the Section Antibiotics in Animal Health)

Multidrug-Resistant Pathogens: Genomic Analysis, Resistance Mechanisms, and Clinical Challenges

edited by

Dusan Kekic

and Nemanja Stanisavljevic

submission deadline 31 Jul 2025 | 1 articles | Viewed by 948 | Submission Open

Keywords: multidrug-resistant pathogens; genomic analysis; antimicrobial resistance; resistance mechanisms; antimicrobial therapy challenges; new antimicrobial drugs and therapies; clinical antimicrobial guidelines

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotics Resistance in Animals and the Environment, 2nd Edition

edited by

Anil Poudel

submission deadline 31 Jul 2025 | 1 articles | Viewed by 449 | Submission Open

Keywords: antimicrobial resistance; environment; epidemiology; genomics; multi-drug resistance; sympatric; wildlife

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Helicobacter pylori Virulence Factors, Antibiotic Susceptibility and Persistent Infection

edited by

Mara Di Giulio

Teresa Fasciana

and

Chiara Pagliuca

submission deadline 31 Jul 2025 | Viewed by 337 | Submission Open

Keywords: Antimicrobial drugs and therapies; virulence factors; pathogenesis; extra-digestive diseases; gastric microbioma

Application of Next Generation Sequencing for Studying the Resistance of Environmental Pathogens

edited by Skoulakis Anargyros and

Efthymia Petinaki

submission deadline 31 Jul 2025 | Viewed by 279 | Submission Open

Keywords: next generation sequencing; metagenome; environmental pathogens; bioinformatics; antimicrobial resistant determinants; virulence factors

Antibacterial and Antibiofilm Properties of Biomaterial

edited by

Ziba Najmi

and Alessandro Calogero Scalia

submission deadline 31 Jul 2025 | Viewed by 232 | Submission Open

Keywords: biomaterials surfaces; coating; biofilm formation; biofilm eradication

(This special issue belongs to the Section Antibiofilm Strategies)

Plant Extracts and Their Derivatives with Antimicrobial Activities

edited by

Latifa Bouissane

and

Natália Cruz-Martins

submission deadline 31 Jul 2025 | Viewed by 182 | Submission Open

Keywords: plant extracts; natural compounds; antimicrobial activities; antimicrobial properties; bioactive

(This special issue belongs to the Section Plant-Derived Antibiotics)

Interdisciplinary Applications of Micro- and Nano-Antimicrobials

edited by Cleonice Gonçalves da Rosa and Michael Ramos Nunes

submission deadline 31 Jul 2025 | Viewed by 165 | Submission Open

Keywords: micro- and nano-antimicrobials; antimicrobial coatings; nanotechnology in medicine; food safety and packaging; agricultural applications; antibiotic resistance; environmental remediation; controlled release systems; pathogen management; antimicrobial materials

(This special issue belongs to the Section Novel Antimicrobial Agents)

Current Challenges in Antimicrobial Stewardship

edited by

Andreas A. Von Ameln-Mayerhofer

submission deadline 31 Jul 2025 | Viewed by 159 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; antibiotics prescribing; intervention; irrational prescriptions; surveillance; therapeutic monitoring; ABS; AMS; antibiotic stewardship; best practice; interprofessional; rational prescribing; DDD/100; RDD/100

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Natural Extracts as Antimicrobial Agents in Infectious Disease Therapy

edited by

Francesca Mariani

submission deadline 31 Jul 2025 | Viewed by 131 | Submission Open

Keywords: medicinal plants; phytocomplexes; essential oils; intracellular bacteria; bacterial cell wall; minimal inhibitory concentration (MIC); minimal bactericidal concentration (MBC); antiadhesive properties; bacterial biofilm; minimal biofilm-inhibiting concentration (MBIC)

(This special issue belongs to the Section Plant-Derived Antibiotics)

Carbapenem Resistant Gram-Negative Pathogens—a Comprehensive Approach to Acinetobacter, Pseudomonas, Enterobacteriaceae, and Stenotrophomonas: A Global Healthcare Threat, 2nd Edition

edited by

Paul F. Riska

and

Darren W. Wong

submission deadline 31 Jul 2025 | Viewed by 104 | Submission Open

Keywords: carbapenem resistance; CRE; Acinetobacter baumannii; Pseudomonas aeruginosa; KPC

Discovery and Design of New Antimicrobial Agents

edited by

Jean Michel Brunel

submission deadline 5 Aug 2025 | 3 articles | Viewed by 5741 | Submission Open

Keywords: antimicrobial agents; fight resistance; new design; structure– activity relationships (SAR)

(This special issue belongs to the Section Novel Antimicrobial Agents)

Natural Alternatives and Their Synthetic Derivatives to Antibiotics

edited by

Simone Carradori

submission deadline 15 Aug 2025 | 3 articles | Viewed by 8773 | Submission Open

Keywords: antibacterial agents; quorum sensing inhibitors; food contamination and preservation; innovative (micro)extraction procedures; synthetic derivatives inspired by natural scaffolds; uses of components from medicinal plants and fungi; biofilm and antimicrobial resistance

(This special issue belongs to the Section Plant-Derived Antibiotics)

Advances in Antimicrobial Strategies to Control Listeria in Food and Clinical Settings

edited by

José Ramos-Vivas

submission deadline 15 Aug 2025 | 1 articles | Viewed by 590 | Submission Open

Keywords: Listeria monocytogenes; antimicrobial agents; biofilms; probiotic strains; mechanisms of resistance

Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms, 3rd Edition

edited by

Anna Duda-Madej

Joanna Kozłowska

and

Katarzyna Wińska

submission deadline 15 Aug 2025 | Viewed by 139 | Submission Open

Keywords: antimicrobial activity; plant extracts; plant-derived compounds; synthetic derivatives; flavonoids; multidrug resistance; pathogenic strains

(This special issue belongs to the Section Plant-Derived Antibiotics)

Feature Papers in Therapy of Diabetic Foot Infections

edited by

Ilker Uckay

and

Laura Soldevila

submission deadline 20 Aug 2025 | 11 articles | Viewed by 32205 | Submission Open

Keywords: diabetic foot infection; diabetic foot osteomyelitis; systemic antibiotic therapy; local antibiotic therapy; side effects; treatment success; antibiotic stewardship; antibiotic policies and difficulties

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Origins and Evolution of Antibiotic Resistance in the Environment

edited by

Damian Rolbiecki

and

Małgorzata Czatzkowska

submission deadline 20 Aug 2025 | Viewed by 198 | Submission Open

Keywords: surface water; soil; wastewater; antibiotic resistance genes; antibiotic resistant bacteria; One Health; WHO pathogens; anthropogenic pressure

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

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