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Special Issues

Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Machine Learning for Antimicrobial Resistance Prediction, 2nd Edition
edited by
submission deadline 10 Jan 2026 | 2 articles | Viewed by 6149 | Submission Open
Keywords: antimicrobial resistance prediction; artificial intelligence; machine learning; infectious diseases
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Rational Use of Antibiotics in Veterinary Medicine
edited by
submission deadline 15 Jan 2026 | 2 articles | Viewed by 9992 | Submission Open
Keywords: good manufacturing practice (GMP) in antibiotic production; research and systems in antibiotic quality control; consequences of improper antibiotic use; antibiotic stewardship programs; antibiotic resistance management
(This special issue belongs to the Section Antibiotics in Animal Health)
Antibiotic Resistance: The Role of Aquatic Environments
edited by and Matthew D. Stocker
submission deadline 15 Jan 2026 | 2 articles | Viewed by 4362 | Submission Open
Keywords: antibiotic resistance; water; wastewater; One Health; antibiotic misuse; antimicrobial resistance genes; microbiology; fecal indicator bacteria; mobile genetic elements; resistome; pollution; environment; water bodies; water treatment; waterborne disease; public health; risk assessment; sanitation; hygiene; aquatic environments
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
The Discovery of Novel Beta-Lactams and Beta-Lactamase Inhibitors
edited by and
submission deadline 15 Jan 2026 | Viewed by 426 | Submission Open
Keywords: antibiotic resistance; β -lactam antibiotics; β -lactamase inhibitors; drug discovery; metallo-β -lactamases; serine-β -lactamase
Strategies for Combating Antibiotic Resistance: From Mechanisms to Drug Discovery
edited by Angel Leon-Buitimea
submission deadline 15 Jan 2026 | Viewed by 273 | Submission Open
Keywords: antibiotic resistance; clinically relevant bacteria; multidrug-resistant bacteria; pan-drug-resistant bacteria; drug discovery; combinatorial treatments
Advances in Antimicrobial Treatment of Periodontitis
edited by
submission deadline 15 Jan 2026 | Viewed by 254 | Submission Open
Keywords: periodontitis; periodontal chemotherapy; anti-infective periodontal therapy; antibiotic therapy
Molecular and Therapeutic Insights into Antimicrobial Candidates and Antibiotics submission deadline 15 Jan 2026 | Viewed by 229 | Submission Open
Keywords: antimicrobial resistance; novel antimicrobial agents; molecular mechanisms; therapeutic applications
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
New Insights into Prevention, Diagnosis, and Treatment of Neonatal Sepsis and Short- and Long-Term Outcomes
edited by , and Maria Baltogianni
submission deadline 20 Jan 2026 | 2 articles | Viewed by 5443 | Submission Open
Keywords: neonate; sepsis; early sepsis; late sepsis; antibiotic resistance; multiple resistance antibiotics; antibiotics stewardship
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Antibiotic Use and Stewardship in Settings Outside of Acute Hospitals
edited by Monsey McLeod and Naomi Fleming
submission deadline 30 Jan 2026 | 1 articles | Viewed by 627 | Submission Open
Keywords: antimicrobial stewardship; antibiotic use; community; primary care; mental health; local authority; care home; public; health and justice; dental
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Discovery and Synthesis of Antimicrobial Compounds Against Multidrug Resistance
edited by
submission deadline 31 Jan 2026 | 4 articles | Viewed by 43510 | Submission Open
Keywords: antimicrobial resistance; medicinal chemistry; (pre)clinical development; intrinsic/synergistic activity; innovative antibiotic treatment; antimicrobial drug-candidate; new and repurposed medicines
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antibiotic Resistance in Wastewater Treatment Plants
edited by Qingbin Yuan
submission deadline 31 Jan 2026 | 5 articles | Viewed by 9840 | Submission Open
Keywords: antibiotic resistance genes; wastewater treatment; one health; distribution and removal of ARGs; horizontal gene transfer
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Multidrug-Resistant Gram-Negative Bacteria Infections: Current Epidemiology, Prognosis and Treatment Options
edited by Novella Carannante
submission deadline 31 Jan 2026 | 5 articles | Viewed by 9524 | Submission Open
Keywords: multidrug-resistant gram-negative bacteria; epidemiology and prognosis; antibiotic treatment options; antimicrobial resistance; infection control and antibiotic use
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Advances in the Field of Biofilm-Associated Musculoskeletal Infections
edited by
submission deadline 31 Jan 2026 | 5 articles | Viewed by 9507 | Submission Open
Keywords: musculoskeletal infections; biofilm-associated; mycobacterial-associated; implant-related infections
(This special issue belongs to the Section Antibiofilm Strategies)
Microbial Biofilms: Identification, Resistance and Novel Drugs submission deadline 31 Jan 2026 | 3 articles | Viewed by 8644 | Submission Open
Keywords: biofilm; resistance; pathogens; alternative treatment; plant extract; peptides; nanotechnology
(This special issue belongs to the Section Antibiofilm Strategies)
Challenges and Strategies for the Antibiotic Resistance Crisis submission deadline 31 Jan 2026 | 4 articles | Viewed by 7803 | Submission Open
Keywords: antibiotics stewardship; antimicrobial use; antibiotics resistance; novel antimicrobial agents; multidisciplinary antimicrobial strategies; antibiotic clinical studies; artificial intelligence strategies
Single-Stage Management of Musculo-Skeletal Infections: Local Antibacterial Protection, Antibiotics, and Surgical Treatments submission deadline 31 Jan 2026 | 3 articles | Viewed by 7249 | Submission Open
Keywords: knee arthroplasty; hip arthroplasty; shoulder arthroplasty; antibiotic treatment; one-stage revision arthroplasty; antibacterial coating
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
The Appropriateness of Antibiotic Prescribing in Hospitals and Ambulatory Care
edited by , Roberto Langella and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 6022 | Submission Open
Keywords: pharmacology; antimicrobic resistance; governance; appropriateness; infectivology
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Tracking Reservoirs of Antimicrobial Resistance Genes in Environment submission deadline 31 Jan 2026 | 3 articles | Viewed by 5502 | Submission Open
Keywords: antimicrobial resistance; AMR; environmental reservoirs; antibiotic resistance genes; ARGs; horizontal gene transfer
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Antifungal Strategies: Epidemiological Approaches, Mechanisms and Resistance in Fungal Pathogens submission deadline 31 Jan 2026 | 3 articles | Viewed by 4525 | Submission Open
Keywords: antifungal strategies; epidemiology; antifungal resistance; antifungal mechanisms; resistance genes
(This special issue belongs to the Section Fungi and Their Metabolites)
The Antibiotic Resistance and Virulence Genes of Pathogens in Aquatic and Soil Environment
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 3218 | Submission Open
Keywords: antibiotic resistance genes (ARGs); virulence genes; pathogenic bacteria; horizontal gene transfer
Antimicrobial Stewardship in Surgical Infection
edited by Nuno Rocha-Pereira
submission deadline 31 Jan 2026 | 3 articles | Viewed by 2683 | Submission Open
Keywords: antimicrobial stewardship; surgical infection; surgical site infection; antimicrobial resistance; diagnostic stewardship
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Diagnostics and Antibiotic Therapy in Bone and Joint Infections
edited by Sebastian Meller and Stavros Goumenos
submission deadline 31 Jan 2026 | 4 articles | Viewed by 1814 | Submission Open
Keywords: bone and joint infections; osteomyelitis; implant-related infections; diagnostics; antimicrobials; antibiotic therapy; PJI management; surgical site antisepsis; local antibiotic therapy; diagnostic biomarkers; multidisciplinary infection management; outcome analysis after musculoskeletal infection
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Advances in Antimicrobial Therapies for Oral Infections: From Biofilm Disruption to Clinical Applications submission deadline 31 Jan 2026 | 1 articles | Viewed by 1452 | Submission Open
Keywords: oral infections; microbial biofilm; antimicrobial therapies
(This special issue belongs to the Section Antibiofilm Strategies)
Helicobacter pylori Virulence Factors, Antibiotic Susceptibility and Persistent Infection submission deadline 31 Jan 2026 | 1 articles | Viewed by 1055 | Submission Open
Keywords: Antimicrobial drugs and therapies; virulence factors; pathogenesis; extra-digestive diseases; gastric microbioma
Antimicrobial Resistance Genes: Spread and Evolution, 2nd Edition
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1032 | Submission Open
Keywords: microbes; antimicrobial resistance; resistance genes; gene flow; evolution
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Superbugs Unleashed: Global Challenges and Solutions for Extensively Drug-Resistant and Pan-Drug-Resistant Pathogens submission deadline 31 Jan 2026 | 1 articles | Viewed by 855 | Submission Open
Keywords: antimicrobial resistance; extensively drug-resistant pathogens; pan-drug-resistant bacteria; multidrug-resistant organisms (MDROs); infectious disease control; antibiotic stewardship; novel antimicrobials; rapid diagnostics; global health threats
Evidence-Based Antibiotic Protocols and Digital Innovation in Oral Infection Management: Optimizing Use Through Teledentistry and Modern Diagnostics
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 745 | Submission Open
Keywords: antibiotics; dental infections; oral infections; antibacterial resistance; telemedicine; teledentistry; antimicrobial management; AI-related
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Bacterial Infections and Global Health: The Escalating Threat of Antibiotic Resistance submission deadline 31 Jan 2026 | Viewed by 602 | Submission Open
Keywords: infection control; antimicrobial stewardship; spread of multidrug-resistant bacteria; methicillin-resistant Staphylococcus aureus; carbapenemases; metallo-β -Lactamase; microbiology diagnostics in field hospitals; One Health
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Dermatological Infections and Antibiotic Treatment
edited by
submission deadline 31 Jan 2026 | Viewed by 503 | Submission Open
Keywords: dermatological infections; antibiotic resistance; antibiotics; antibiotic treatment
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
A Themed Issue in Honor of Prof. Dr. Fausto Catena—Outstanding Contributions in the Fields of Antibiotics in the Acute Care and Emergency
edited by Carlo Vallicelli
submission deadline 31 Jan 2026 | Viewed by 482 | Submission Open
Keywords: emergency surgery; intra-abdominal infections; antibiotic treatment; trauma surgery; sepsis
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Neonatal Infection: Antibiotics for Prevention and Treatment
edited by Cinzia Auriti and Maria Paola Ronchetti
submission deadline 31 Jan 2026 | 1 articles | Viewed by 414 | Submission Open
Keywords: neonatal infections; neonatal sepsis; sepsis definition; antibiotics in newborns; antibiotic stewardship; sepsis biomarkers; sepsis diagnosis in newborns; epidemiology of neonatal infections; fungal invasive infections
Foodborne Pathogens: The Rise of Virulence and Antimicrobial Resistance submission deadline 31 Jan 2026 | Viewed by 410 | Submission Open
Keywords: foodborne pathogens; antimicrobial resistance; virulence factors; food chain; antibiotic overuse; public health; food safety; zoonotic diseases; one health
A Themed Issue in Honor of Professor Aditya Gupta—Outstanding Contributions to Antifungal Therapy, Dermatology and Mycology
edited by Ditte Marie Saunte and Mesbah Talukder
submission deadline 31 Jan 2026 | Viewed by 372 | Submission Open
Keywords: onychomycosis; antifungal resistance; dermatophyte infections; antifungal stewardship; Trichophyton indotineae; topical and oral antifungals; treatment algorithms; epidemiology of onychomycosis
Molecular Diagnostics and Antimicrobial Resistance in Animal Pathogens
edited by Mariela E. Srednik and
submission deadline 31 Jan 2026 | Viewed by 337 | Submission Open
Keywords: antimicrobial susceptibility; molecular diagnostic; antimicrobial resistance; animal pathogens; bacterial diseases
(This special issue belongs to the Section Antibiotics in Animal Health)
Nanoparticles as Novel Solutions to Microbial Resistance in Hospital Care submission deadline 31 Jan 2026 | Viewed by 322 | Submission Open
Keywords: nanoparticles; antibiotic resistance; nosocomial infections; MRSA; VRSA; antimicrobial properties; multi-drug resistance
(This special issue belongs to the Section Antimicrobial Materials and Surfaces)
Advances in the Diagnosis and Antibiotic Treatments of Diabetic Foot Infections submission deadline 31 Jan 2026 | Viewed by 277 | Submission Open
Keywords: diabetic foot; diabetic foot ulcer; diabetic foot osteomyelitis; antibiotics; treatment
Membrane Disruptors: The Role of Antimicrobial Peptides in Combatting Pathogens
edited by
submission deadline 31 Jan 2026 | Viewed by 271 | Submission Open
Keywords: antimicrobial peptides (AMPs); microbial resistance; drug-resistant pathogens; anticancer; antiviral; membrane disruption; membrane poration; permeabilization; lipids; peptide design and engineering
(This special issue belongs to the Section Antimicrobial Peptides)
Antibiotic or Antibiotic Adjuvant Synthesis and Antimicrobial Evaluation, 2nd Edition
edited by
submission deadline 31 Jan 2026 | Viewed by 234 | Submission Open
Keywords: antimicrobial agents; synergy; adjuvants; bacterial resistance
Antimicrobial Resistance (AMR) in the Food Chain: Detection Gaps and Mitigation Strategies submission deadline 31 Jan 2026 | Viewed by 224 | Submission Open
Keywords: antimicrobial resistance (AMR); foodborne pathogens; surveillance; detection methods; mitigation strategies; One Health
(This special issue belongs to the Section Antibiotics in Animal Health)
Epidemiology of Antimicrobial-Resistant Pathogens in Animals: A One Health Perspective submission deadline 31 Jan 2026 | Viewed by 181 | Submission Open
Keywords: antimicrobial resistance (AMR); veterinary epidemiology; one health; zoonotic pathogens; surveillance systems; molecular epidemiology; resistance mechanisms
(This special issue belongs to the Section Antibiotics in Animal Health)
Antimicrobial Resistance in Bacterial Pathogens: Insights from Veterinary Medicine submission deadline 31 Jan 2026 | Viewed by 131 | Submission Open
Keywords: antimicrobial resistance (AMR); veterinary medicine; One Health; animal health; zoonotic transmission; surveillance and monitoring
(This special issue belongs to the Section Antibiotics in Animal Health)
A Themed Issue in Honor of Prof. Jae-hyuk Yu—Antimicrobial Resistance in the Foodborne Pathogens
edited by and Ahmad Alshannaq
submission deadline 1 Feb 2026 | 1 articles | Viewed by 1169 | Submission Open
Keywords: foodborne pathogens; antimicrobial resistance (AMR); food safety; antimicrobial preservation; food additives; antimicrobial resistance mechanisms
Bacterial Zoonotic Infections: Epidemiology, Virulence Mechanisms, Antimicrobial Resistance and Antibiotic Treatment
edited by and Inés Bado
submission deadline 5 Feb 2026 | Viewed by 105 | Submission Open
Keywords: antimicrobial resistance; zoonotic bacteria; zoonotic infection; one health
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Livestock Antibiotic Use and Resistance
edited by Valentina Monistero, , and Valerio Bronzo
submission deadline 15 Feb 2026 | 7 articles | Viewed by 31705 | Submission Open
Keywords: farm; livestock; antibiotic; antimicrobial resistance; One Health; multidrug-resistant; methicillin-resistant; extended-spectrum beta-lactamase; carbapenemase; superbug
(This special issue belongs to the Section Antibiotics in Animal Health)
Experimental Models and Novel Therapies for Difficult-to-Treat Biofilm-Associated Infections
edited by and
submission deadline 15 Feb 2026 | 1 articles | Viewed by 418 | Submission Open
Keywords: biofilm-associated infections; antimicrobial resistance; experimental models (in vitro / in vivo); novel anti-biofilm therapies; antibiotic tolerance; combination therapy; antimicrobial peptides; phage therapy
Omics Approaches, Including Culturomics, for Assessing Antimicrobial Resistance in Bacterial Communities submission deadline 15 Feb 2026 | Viewed by 227 | Submission Open
Keywords: omics; culturomics; MALDI-TOF; antimicrobial resistance; gut microbiota
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Innovations in Antibacterial Agents: Combating Resistance, Improving Efficacy and Exploring New Mechanisms
edited by and
submission deadline 20 Feb 2026 | 4 articles | Viewed by 12843 | Submission Open
Keywords: drug design; synthesis of novel antibacterial agents; computational chemistry; repurposing of drugs; novel antibacterial mechanisms
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antimicrobial Resistance in Biofilm-Associated Infections submission deadline 25 Feb 2026 | 5 articles | Viewed by 12111 | Submission Open
Keywords: biofilms; antimicrobial resistance; chronic infections; biofilm matrix; virulence factors; antibiotic efficacy; pathogen persistence; biofilm formation; medical implants; quorum sensing
(This special issue belongs to the Section Antibiofilm Strategies)
Feature Papers in Therapy of Diabetic Foot Infections submission deadline 28 Feb 2026 | 11 articles | Viewed by 46846 | Submission Open
Keywords: diabetic foot infection; diabetic foot osteomyelitis; systemic antibiotic therapy; local antibiotic therapy; side effects; treatment success; antibiotic stewardship; antibiotic policies and difficulties
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Nanoparticles as Antibacterial/Antibiofilm Agents
edited by
submission deadline 28 Feb 2026 | 9 articles | Viewed by 31802 | Submission Open
Keywords: nanoparticles; antibacterial; biofilm; mechanism; antibiotic resistance
(This special issue belongs to the Section Antimicrobial Materials and Surfaces)
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