Special Issues

Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Approaches in Antimicrobial Drug Discovery and Design
edited by
submission deadline 10 May 2025 | 1 articles | Viewed by 4031 | Submission Open
Keywords: rational drug design; multi-drug resistant human pathogenic bacteria; new antibiotics; antibacterial drugs; antibacterial drug targets; in silico drug target evaluation
(This special issue belongs to the Section Novel Antimicrobial Agents)
Efflux Pumps in Bacteria: What They Do and How We Can Stop Them
edited by
submission deadline 15 May 2025 | 8 articles | Viewed by 35033 | Submission Open
Keywords: new antibiotics; bioactive medicinal agents; classes of antibiotics; antibiotic resistance and misuse; natural antibiotics; microbial efflux pumps; efflux pump inhibitors
(This special issue belongs to the Section Antibiofilm Strategies)
Antibiotics Resistance in Gram-Negative Bacteria, 2nd Edition
edited by
submission deadline 15 May 2025 | 7 articles | Viewed by 16457 | Submission Open
Keywords: antimicrobial resistance; epidemiology; genomics surveillance; One-Health; enterobacteriaceae; repurposing; bacteriophages; antimicrobial peptides; natural compounds; virulence profiles
The Search for Antimicrobial Agents from Natural Products
edited by Carolina P. Reyes and
submission deadline 15 May 2025 | 6 articles | Viewed by 12692 | Submission Open
Keywords: natural products; antimicrobial agents; drug discovery; mechanism of action; pharmacology
(This special issue belongs to the Section Plant-Derived Antibiotics)
Antimicrobial Treatment and Management of Central Nervous System Infections
edited by Liana Signorini and Angelo Pan
submission deadline 15 May 2025 | 5 articles | Viewed by 10069 | Submission Open
Keywords: central nervous system; CNS; hospital-acquired infection; nosocomial; neurosurgery; external ventricular drainage; EVD; post-neurosurgical meningitis; bacterial colonization
Machine Learning for Antimicrobial Resistance Prediction, 2nd Edition
edited by
submission deadline 15 May 2025 | 1 articles | Viewed by 2549 | Submission Open
Keywords: antimicrobial resistance prediction; artificial intelligence; machine learning; infectious diseases
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
What’s New: Natural and Synthetic Antibacterials and/or Agents with Multiple Activities? (3rd Edition) submission deadline 15 May 2025 | 1 articles | Viewed by 2409 | Submission Open
Keywords: natural antibacterials; synthetic antibacterials; antitumorals; antivirals; antioxidants; antifungals; anti-inflammatory
(This special issue belongs to the Section Novel Antimicrobial Agents)
Therapeutic Drug Monitoring of Antimicrobials in Critically Ill Patients
edited by Young Ran Lee
submission deadline 15 May 2025 | 1 articles | Viewed by 1898 | Submission Open
Keywords: therapeutic drug monitoring (TDM); antibiotics; antimicrobials; pharmacokinetic; pharmacodynamic; critically ill
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Clostridioides difficile Infection, 3rd Edition
edited by
submission deadline 15 May 2025 | 1 articles | Viewed by 1837 | Submission Open
Keywords: Clostridioides difficile; Clostridioides difficile infection recurrence; antimicrobial use; host and microbiota interaction; CDI
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Genomic Analysis of Drug-Resistant Pathogens
edited by
submission deadline 20 May 2025 | 2 articles | Viewed by 3366 | Submission Open
Keywords: multi-drug resistant; mutation; bacteria; NGS; sequencing; mobile genetics elements; gene transfer
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Carbapenem-Resistant Enterobacteriaceae: Epidemiology, Detection and Treatment
edited by Seung Soon Lee
submission deadline 20 May 2025 | Viewed by 143 | Submission Open
Keywords: carbapenem-resistant Enterobacterales (CRE); antibiotic treatment; epidemiology
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Detection of Bacteria and Antibiotics Surveillance in Livestock submission deadline 30 May 2025 | 10 articles | Viewed by 10917 | Submission Open
Keywords: livestock; bacteria; pathogens; antibiotic resistance; antibiotic surveillance; zoonoses
(This special issue belongs to the Section Antibiotics in Animal Health)
Bioactive Peptides and Their Antibiotic Activity
edited by
submission deadline 30 May 2025 | 5 articles | Viewed by 9220 | Submission Open
Keywords: database peptides; therapeutic agents; peptide design; antimicrobial peptides; antibiotic resistance; therapeutic drugs
(This special issue belongs to the Section Antimicrobial Peptides)
Pharmacokinetic and Antibiotic Dosing for Intensive Care Unit Patients
edited by
submission deadline 31 May 2025 | 8 articles | Viewed by 22214 | Submission Open
Keywords: antibiotics; pharmacokinetics-pharmacodynamics; therapeutic drug monitoring; population pharmacokinetics analysis; bacterial susceptibility
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Nanoparticles as Antibacterial/Antibiofilm Agents
edited by
submission deadline 31 May 2025 | 7 articles | Viewed by 21514 | Submission Open
Keywords: nanoparticles; antibacterial; biofilm; mechanism; antibiotic resistance
(This special issue belongs to the Section Antimicrobial Materials and Surfaces)
Phage Applications from Diagnostics to Treatment of Bacterial Infections in a One Health World submission deadline 31 May 2025 | 8 articles | Viewed by 20152 | Submission Open
Keywords: phage therapy; antibiotic resistance; bacteriophages; regulatory framework; veterinary medicine; agriculture treatment; aquaculture
(This special issue belongs to the Section Bacteriophages)
Microbial Resistance to Carbapenems: Epidemiology, Detection and Treatment Options submission deadline 31 May 2025 | 9 articles | Viewed by 19150 | Submission Open
Keywords: carbapenems; carbapenemases; Gram-negatives; multidrug resistance (MDR); carpabenem-resistant organisms (CROs); antimicrobial resistance; carbapenem resistance detection; epidemiology; antibiotics; carbapenem-resistant Gram-negative bacteria (CRGNB)
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Successful Antimicrobial Stewardship Approaches to Address Nosocomial Infections submission deadline 31 May 2025 | 6 articles | Viewed by 17727 | Submission Open
Keywords: bacterial; resistance; antimicrobial; stewardship
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobial Resistance and Epidemiological Study of Clinically Relevant Pathogens submission deadline 31 May 2025 | 8 articles | Viewed by 17130 | Submission Open
Keywords: antibacterial activity; antimicrobial resistance; infections; multidrug-resistant pathogens; virulence gene expression; drug discovery; epidemiological study
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 2nd Edition submission deadline 31 May 2025 | 11 articles | Viewed by 14666 | Submission Open
Keywords: epidemiology; social behavior; antibiotic resistance; social factors; attitudes; knowledge; practice; qualitative research; public health interventions; antibiotic prescription; community care
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antibiotic Use in Outpatients and Hospitals
edited by
submission deadline 31 May 2025 | 7 articles | Viewed by 14538 | Submission Open
Keywords: antimicrobial resistance; outpatient; epidemiology; in hospital infections; antibiotic stewardship; source control; antibiotic prescribing
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antibiofilm Activity against Multidrug-Resistant Pathogens
edited by and Petar Knezevic
submission deadline 31 May 2025 | 6 articles | Viewed by 13896 | Submission Open
Keywords: biofilm; microbial drug resistance; antibiofilm agents; antibiofilm strategies; synergistic interactions
(This special issue belongs to the Section Antibiofilm Strategies)
Insights into Natural Antimicrobial Peptides submission deadline 31 May 2025 | 4 articles | Viewed by 11552 | Submission Open
Keywords: antibacterial host defense peptides; antibacterial mode of action; defensins; cathelicidins; insect antimicrobial peptides; plant antimicrobial peptides
(This special issue belongs to the Section Antimicrobial Peptides)
Antibiotic Resistance and Coping Strategies of Methicillin-Resistant Staphylococcus Species
edited by
submission deadline 31 May 2025 | 5 articles | Viewed by 9226 | Submission Open
Keywords: Staphylococcus aureus; methicillin resistance; MRSA; multidrug resistance; MDR; alternative therapies
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Molecular Mechanism of Antibiotic Resistance in Microbial Biofilms
edited by Patricia Pérez-Palacios
submission deadline 31 May 2025 | 4 articles | Viewed by 8918 | Submission Open
Keywords: biofilms; antibiotic resistance; resistance mechanisms
(This special issue belongs to the Section Antibiofilm Strategies)
Advancing the Discovery and Development of New Antibiotics through Drug Repurposing
edited by Songping Huang
submission deadline 31 May 2025 | 4 articles | Viewed by 8364 | Submission Open
(This special issue belongs to the Section Novel Antimicrobial Agents)
Evaluation of Emerging Antimicrobials submission deadline 31 May 2025 | 4 articles | Viewed by 7916 | Submission Open
Keywords: antibacterials; antibiotics; antifungals; antimicrobial agents; antimicrobial resistance; antivirals; bacterial resistance; infections; multidrug resistance; pathogens
Antimicrobial Stewardship Intervention: Importance for Clinical Practice and Health Policy
edited by and
submission deadline 31 May 2025 | 4 articles | Viewed by 7590 | Submission Open
Keywords: antimicrobial stewardship; antibiotic use; implementation science; interventions; clinical guidelines; health policy
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Neonatal Infections: Epidemiology, Diagnostics and Antibiotic Therapeutics
edited by
submission deadline 31 May 2025 | 3 articles | Viewed by 6770 | Submission Open
Keywords: newborn; infant; neonate; infection; sepsis; early-onset sepsis; late-onset sepsis; antibiotics; antibiotic stewardship
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Nanomaterials as Antimicrobial Agents for Biomedical Applications submission deadline 31 May 2025 | 3 articles | Viewed by 6345 | Submission Open
(This special issue belongs to the Section Antimicrobial Materials and Surfaces)
Multitalented Synthetic Antimicrobial Compounds: From Design to Effect submission deadline 31 May 2025 | 4 articles | Viewed by 5696 | Submission Open
Keywords: antimicrobial resistance; antibiotic development; the design of antimicrobial compounds; the synthesis of antimicrobial compounds; medicinal chemistry; bioorganic chemistry; antimicrobial properties; the mechanisms of antimicrobial activity; bioinorganic
(This special issue belongs to the Section Novel Antimicrobial Agents)
Epidemiological Data on Antibiotic Resistance
edited by
submission deadline 31 May 2025 | 2 articles | Viewed by 5601 | Submission Open
Keywords: antibiotic resistance; experimental models; antibiotic resistance selection; antibiotic resistance evolution pathways; antibiotic resistance phenotypes; antibiotic resistance genotypes; antibiotic resistance mechanisms; antibiotic resistance cost; antibiotic resistance prevention and control; antibiotic resistance reversion
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Metagenomics for Surveillance of Pathogens and/or Antimicrobial Resistance
edited by Rommel Thiago Jucá Ramos
submission deadline 31 May 2025 | 2 articles | Viewed by 5410 | Submission Open
Keywords: antimicrobial resistance; metagenomics; pathogen; environmental surveillance; clinical; one health
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Antibiotic Use in the Communities—2nd Edition submission deadline 31 May 2025 | 6 articles | Viewed by 4807 | Submission Open
Keywords: antibiotic use; community; behavior; socioeconomic factors; culture; values
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Methods for Preventing Biofilm Formation and Treat the Infections Caused by Biofilm Formed on Biotics or Abiotic Surfaces submission deadline 31 May 2025 | 3 articles | Viewed by 4565 | Submission Open
Keywords: biofilms; infection; prevention; treatment
(This special issue belongs to the Section Antibiofilm Strategies)
Emerging Treatment Options for Multidrug-Resistant Bacterial and Fungal Infections, 2nd Edition submission deadline 31 May 2025 | 2 articles | Viewed by 4515 | Submission Open
Keywords: MDR bacteria; antibiotic resistance; new antimicrobial; MDR fungi; antifungal therapies; alternative strategies
Bacteriophages and Phage-Derived Enzymes as Antibacterial Agents
edited by
submission deadline 31 May 2025 | 2 articles | Viewed by 2594 | Submission Open
Keywords: phage therapy; lytic bacteriophages; phage-derived enzymes; antibiotic resistance
(This special issue belongs to the Section Bacteriophages)
The Appropriateness of Antibiotic Prescribing in Hospitals and Ambulatory Care
edited by , Roberto Langella and
submission deadline 31 May 2025 | 1 articles | Viewed by 2575 | Submission Open
Keywords: pharmacology; antimicrobic resistance; governance; appropriateness; infectivology
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Single-Stage Management of Musculo-Skeletal Infections: Local Antibacterial Protection, Antibiotics, and Surgical Treatments submission deadline 31 May 2025 | 2 articles | Viewed by 2483 | Submission Open
Keywords: knee arthroplasty; hip arthroplasty; shoulder arthroplasty; antibiotic treatment; one-stage revision arthroplasty; antibacterial coating
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Mechanisms of Biofilm Development and Antibiofilm Therapeutics Strategies submission deadline 31 May 2025 | 1 articles | Viewed by 1733 | Submission Open
Keywords: biofilm; polymicrobial biofilms; biofilm development; biofilm eradication; antibiofilm activity; targeted anti-biofilm therapy; EPS; quorum sensing; metabolic; AMP; biofilm penetration; enhanced antimicrobial therapy; multi-immunotherapy
(This special issue belongs to the Section Antibiofilm Strategies)
Genetic Mechanisms of Bacterial Survival: Antibiotic Resistance and Defense Strategies
edited by and Thiago Pavoni Gomes Chagas
submission deadline 31 May 2025 | 1 articles | Viewed by 654 | Submission Open
Keywords: antimicrobial resistance mechanisms; disinfectant and antiseptic resistance; biofilm formation; genomic insights; horizontal gene transfer
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Therapy of Infectious Diseases Among Children and Adults: The Role of Antibiotics in Daily Practice submission deadline 31 May 2025 | Viewed by 653 | Submission Open
Keywords: аntibiotic use among children; аntibiotic use among adults; аntibiotic use among outpatients; аntibiotic use among inpatients; antibiotic resistance; improper antibiotic use; antibiotic quality control
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Combatting Dental Infections: Insights into Oral Microbiota and Antibiotic Therapy
edited by and
submission deadline 31 May 2025 | Viewed by 428 | Submission Open
Keywords: oral microbiota; dental diseases; systematic disease; antimicrobial; therapeutic strategies; oral biomaterials; oral probiotics; infectious disease; oral microecology; targets
Optimizing Antimicrobial Therapy in NICU Settings: Strategies and Implications submission deadline 31 May 2025 | Viewed by 306 | Submission Open
Keywords: neonatal ICU; antimicrobial stewardship; antimicrobial resistance; neonatal sepsis; biomarkers
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Global Perspectives on Antimicrobial Stewardship and Food Safety
edited by
submission deadline 31 May 2025 | Viewed by 236 | Submission Open
Keywords: antimicrobial resistance; antimicrobial use; food systems; food safety; antimicrobial stewardship
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Foodborne Pathogens: Detection, Resistance Mechanisms, and Control Strategies
edited by
submission deadline 31 May 2025 | Viewed by 218 | Submission Open
Keywords: foodborne pathogens; antimicrobial resistance; rapid detection methods; control strategies; food safety interventions; One Health
Impact of Antimicrobial Stewardship on Healthcare-Associated Infections
edited by
submission deadline 31 May 2025 | Viewed by 131 | Submission Open
Keywords: antimicrobial stewardship; hospitals; antimicrobial resistance; antimicrobial stewardship interventions
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Advances in the Field of Biofilm-Associated Musculoskeletal Infections
edited by
submission deadline 5 Jun 2025 | 1 articles | Viewed by 879 | Submission Open
Keywords: musculoskeletal infections; biofilm-associated; mycobacterial-associated; implant-related infections
(This special issue belongs to the Section Antibiofilm Strategies)
Design, Synthesis and Biological Evaluation of Antibacterial Compounds submission deadline 15 Jun 2025 | 2 articles | Viewed by 3624 | Submission Open
Keywords: antibacterial agents; antifungal agents; antibiotics; antimicrobial resistance; drug discovery; medicinal chemistry
(This special issue belongs to the Section Novel Antimicrobial Agents)
Spread of Multidrug-Resistant Microorganisms, 2nd Edition submission deadline 15 Jun 2025 | 1 articles | Viewed by 2636 | Submission Open
Keywords: multidrug-resistant organisms; MDR; antibiotic resistance gene; nosocomial infections; new marker of resistance
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