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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Strategies for the Design of Hybrid-Based Antimicrobial Compounds

edited by

Vuyolwethu Khwaza

Sibusiso Alven

and

Blessing Atim Aderibigbe

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3569 | Submission Open

Keywords: hybrid compounds; antimicrobial agents; antibacterial agents; antifungal activity; antiviral activity; in vitro evaluation; structure– activity relationship (SAR); bioactive molecules; nanoformulations; targeted drug delivery; pharmacological screening; clinical studies

(This special issue belongs to the Section Novel Antimicrobial Agents)

Evidence in Antibiotic Mastitis Therapy

edited by

Volker Krömker

and

Paolo Moroni

submission deadline 30 Apr 2026 | 1 articles | Viewed by 3431 | Submission Open

Keywords: antibiotic mastitis treatment; targeted; selective; pathogens; mastitis history; new infections

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Peptides: An Emerging Hope in the Era of New Infections and Resistance, 2nd Edition

edited by

Piyush Baindara

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2995 | Submission Open

Keywords: antimicrobial peptides; antimicrobial resistance; infectious diseases; antibacterial; antifungal; immunomodulatory properties; therapeutics; evolution

(This special issue belongs to the Section Antimicrobial Peptides)

Antimicrobial Resistance, Epidemiology, Clinical Impact and Molecular Characterization of Multidrug-Resistant ESKAPEE Pathogens

edited by

Lorenzo Pace

and Viviana Manzulli

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1550 | Submission Open

Keywords: ESKAPEE; antimicrobial resistance; antibiotic resistance; multidrug-resistant pathogens; nosocomial infection; molecular mechanism

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Epidemiology and Antimicrobial Dosing Regimens in Intensive Care Units

edited by

Philipp Simon

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1535 | Submission Open

Keywords: epidemiology; critical care; sepsis; empiric therapy; dosing; interactions; antibiotic resistance; therapeutic drug monitoring; pharmacokinetics/pharmacodynamics; renal insufficiency; renal replacement therapy

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)

Fighting the Superbug Surge: Strategies in Antimicrobial Stewardship and Infection Control

edited by Sara Revolinski, Kristen Bresnehan and Lucas Schulz

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1115 | Submission Open

Keywords: antimicrobial stewardship; infection control; infection prevention; multidrug resistant organisms; antimicrobial resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Plant Peptides as Prototypes of New Antifungal Drugs

edited by

Ekaterina I. Finkina

submission deadline 30 Apr 2026 | 1 articles | Viewed by 768 | Submission Open

Keywords: fungal infections; fungal virulence factors; fungal resistance; plant antimicrobial peptides (AMPs); antifungal activity; prevention of fungal adhesion and biofilm formation; immunomodulatory properties; structure-activity relationships; peptide engineering

Distribution, Sources and Risks of Bacteria and Their Antimicrobial Resistance Genes in the Environment, 2nd Edition

edited by Filip Gamoń,

Ewa Kotlarska

and Suparna Mitra

submission deadline 30 Apr 2026 | 1 articles | Viewed by 674 | Submission Open

Keywords: antimicrobial resistance (AMR) and One Health; AMR dissemination in the environment; risk assessment of AMR in environmental reservoirs (agroecosystems); antibiotic-resistant pathogenic and resident bacteria; antibiotic-resistance gene (ARG) transfer; ARG quantification; AMR and food/feed chain; antibiotics in animals; agrochemicals; antibiotic residues

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Healthcare-Associated Infections (HAIs): Prevention, Control and Surveillance, 2nd Edition

edited by

Maria Bagattini

submission deadline 30 Apr 2026 | 1 articles | Viewed by 582 | Submission Open

Keywords: healthcare-associated infections (HAIs); infection prevention and control; antimicrobial resistance; HAIs management and control; carbapenem resistant (CR) Enterobacterales; carbapenem resistant (CR) Acinetobacter baumannii

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Design and Synthesis of Novel Antibiotics, 2nd Edition

edited by Kenneth Ikenna Onyedibe

submission deadline 30 Apr 2026 | Viewed by 219 | Submission Open

Keywords: drug discovery; antimicrobial modes of action; antimicrobial resistance; structural characterization; antimicrobial activity

(This special issue belongs to the Section Novel Antimicrobial Agents)

Metal-Based Antibiotics and Therapeutics

edited by

Sotiris K Hadjikakou

and

Christina N. Banti

submission deadline 30 Apr 2026 | Viewed by 210 | Submission Open

Keywords: biological inorganic chemistry; metallotherapeutics; metal-based antibiotics; antimicrobial compounds; antimicrobial resistance (AMR); antimicrobials materials or nanoparticles; active medical devices

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Use and the Emergence of Antibiotic Resistance in Clinical Settings, 2nd Edition

edited by

Aleksandra Barac

submission deadline 30 Apr 2026 | Viewed by 185 | Submission Open

Keywords: antibiotic use; antibiotic resistance; clinical settings; clinical infections; mechanisms underlying the development of resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Therapies for Multidrug-Resistant Infections

edited by

Antonio Riccardo Buonomo

submission deadline 30 Apr 2026 | Viewed by 165 | Submission Open

Keywords: MDR; gram-negative infections; acinteobacter baumannii; stenotrophomonas maltophilia; KPC; MBL

Antibiotic Susceptibility Testing Guides Clinical Treatment Decisions: From Empiric to Targeted Therapy

edited by

Jan Závora

, Simona Arientová and

Christopher K. C. Lai

submission deadline 30 Apr 2026 | Viewed by 150 | Submission Open

Keywords: antimicrobial susceptibility testing; antimicrobial resistance; empiric antimicrobial therapy; targeted antimicrobial therapy; clinical microbiology; infectious diseases; antimicrobial stewardship; infectious disease management; multidrug-resistant organisms

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Advanced Nanomaterials and Bioinspired Strategies for Antimicrobial Applications

edited by

Amedea B. Seabra

, Gerson Nakazato and

Roberta Albino Dos Reis

submission deadline 30 Apr 2026 | Viewed by 146 | Submission Open

Keywords: antimicrobial nanomaterials; bioinspired materials; biomaterials engineering; antimicrobial resistance (AMR); nanostructured antimicrobials; bionanotechnology; green chemistry; antibacterial coatings

(This special issue belongs to the Section Novel Antimicrobial Agents)

Rapid Antifungal Susceptibility Testing and Diagnostics of Antifungal Resistance

edited by Valentina Salas

submission deadline 30 Apr 2026 | Viewed by 144 | Submission Open

Keywords: antifungal resistance; drug resistance mechanisms; multidrug resistance; intrinsic resistance and acquired resistance; new resistant opportunistic fungi

Multidrug-Resistant Microorganisms: Overcoming the Challenges in Antibiotic Treatment

edited by Eleni E. Mylona and

Dimitris Kounatidis

submission deadline 30 Apr 2026 | Viewed by 141 | Submission Open

Keywords: multidrug-resistant; antibiotic treatment; MDR pathogens; therapeutic strategies

Exploring Synthetic Organic Chemistry to Combat Pathogenic Infections

edited by

Cătălin Araniciu

Ioana Ionuț

and

Gabriel Marc

submission deadline 30 Apr 2026 | Viewed by 118 | Submission Open

Keywords: synthetic organic chemistry; antimicrobial agents; structure– activity relationship (SAR); drug design; molecular docking; drug discovery

(This special issue belongs to the Section Novel Antimicrobial Agents)

Plant-Derived Nanoantibiotics: Innovations and Applications

edited by

Luciano Paulino Silva

submission deadline 30 Apr 2026 | Viewed by 111 | Submission Open

Keywords: nanotechnology; plant-derived antibiotics; nanoparticles; antimicrobial resistance; green synthesis; drug delivery; nano-formulations; bioactive compounds; nanoantibiotics

Pharmacokinetic and Antibiotic Dosing for Intensive Care Unit Patients, 2nd Edition

edited by

Yuhki Sato

submission deadline 30 Apr 2026 | Viewed by 109 | Submission Open

Keywords: antibiotics; pharmacokinetics– pharmacodynamics; therapeutic drug monitoring; population pharmacokinetics analysis; bacterial susceptibility

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)

Antibiotics and Environment—Research and Development Toward the One Health Approach, 2nd Edition

edited by

Takashi Azuma

submission deadline 30 Apr 2026 | Viewed by 97 | Submission Open

Keywords: antimicrobial resistance (AMR); antimicrobials; water purification plant (WTP); wastewater treatment plant (WWTP); hospital wastewater; livestock environment; aquaculture farm environment; aquatic environment

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Treatment Challenges in Gastroenterology and Malignancy-Associated Infections: Current Trends, Debates and Future Perspectives

edited by

Ibolya Czegle

and Péter Birinyi

submission deadline 30 Apr 2026 | Viewed by 68 | Submission Open

Keywords: gastroenterology; oncology; antibiotic resistance; antimicrobial treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotics Use in Farms, 3rd Edition

edited by

Linda Bester

submission deadline 30 Apr 2026 | Viewed by 63 | Submission Open

Keywords: non-antibiotic; alternative therapeutic options (to antibiotics); alternative production strategies; vaccines; farm-sourced surveillance of antibiotic resistance; clonal lineages

(This special issue belongs to the Section Antibiotics in Animal Health)

Pathogenesis, Epidemiology and Antibiotic Resistance of Salmonella

edited by

Angela Pista

and

Leonor Silveira

submission deadline 1 May 2026 | 1 articles | Viewed by 1454 | Submission Open

Keywords: Salmonella; epidemiology; genomics; public health; antimicrobial resistance; One-Health approach

Antimicrobial Resistance and Infections in Animals

edited by

John B. Kaneene

submission deadline 10 May 2026 | 8 articles | Viewed by 21204 | Submission Open

Keywords: antimicrobial resistance; mechanisms; humane and societal concerns; risk factors

(This special issue belongs to the Section Antibiotics in Animal Health)

Novel Antimicrobial Strategies to Combat Multidrug-Resistant (MDR) Gram-Negative Bacteria, 2nd Edition

edited by

Valerie Carabetta

submission deadline 10 May 2026 | 2 articles | Viewed by 2848 | Submission Open

Keywords: gram negative; antibiotic resistance; antiseptic resistance; multidrug resistant; extensively drug resistant; pandrug resistant; MDR; XDR; PDR; efflux pumps; mechanisms of resistance; beta-lactamase; outer membrane

Biotechnological Production of Novel Antimicrobials

edited by

Vanja Vlajkov

Jovana Grahovac

and

Ivana Danilov

submission deadline 15 May 2026 | 1 articles | Viewed by 1935 | Submission Open

Keywords: antibiotic resistance; biotechnology; antimicrobial activity; disease outbreak; pathogens; microorganisms; genetic engineering; artificial intelligence; optimisation; biocontrol

A Themed Issue in Honor of Professor Helen Giamarellou—Outstanding Contributions in the Fields of Antimicrobial Resistance and Difficult-to-Treat Resistance Pathogens

edited by Konstantinos Pontikis

submission deadline 20 May 2026 | 6 articles | Viewed by 28362 | Submission Open

Keywords: antibiotic stewardship; nosocomial infections; infection control; epidemiology of resistance plus in vitro investigation of underlying resistance mechanisms; infections in the ICU; neutropenic host infections; indicated therapeutic approach of MDR and XDR gram-negative infections; pharmacokinetics/pharmacodynamics of newer antimicrobial agents

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Evidence-Based Pharmaceutical Care and Rational Antibiotic Use

edited by

Suodi Zhai

and Siyan Zhan

submission deadline 20 May 2026 | Viewed by 123 | Submission Open

Keywords: rational antibiotic use; bacterial resistance; medical institutions; optimization of antibiotic usage and dosages; prescription

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Innovative and Translational Antibiosis Approaches to Tackling Protozoan Parasites: Synergy, Drug Repurposing, Natural Products, Molecular Targets, and Therapeutic Design

edited by

Leonardo Acuña

submission deadline 30 May 2026 | 1 articles | Viewed by 846 | Submission Open

Keywords: drug repurposing for neglected tropical diseases; natural products with antiparasitic activity; synergistic drug combinations; molecular targets and mechanisms of action

Antibiotic Prescribing in Primary Dental Care—2nd Edition

edited by

Kristina Peros

submission deadline 30 May 2026 | Viewed by 179 | Submission Open

Keywords: primary dental care; antibiotic prescribing; rational drug prescribing; antibiotic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Stewardship in Neonatal Intensive Care

edited by Chiara Poggi

submission deadline 30 May 2026 | Viewed by 116 | Submission Open

Keywords: neonatal sepsis; early onset sepsis; late onset sepsis; preterm; antimicrobial stewardship; neonatal intensive care; molecular diagnosis; stopping rule; therapeutic drug monitoring; extended antimicrobial infusion; continuous antimicrobial infusion; microbiological surveillance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiofilm Activity against Multidrug-Resistant Pathogens

edited by

Verica Aleksic Sabo

and Petar Knezevic

submission deadline 31 May 2026 | 7 articles | Viewed by 26064 | Submission Open

Keywords: biofilm; microbial drug resistance; antibiofilm agents; antibiofilm strategies; synergistic interactions

(This special issue belongs to the Section Antibiofilm Strategies)

Mechanism of Carbapenem Resistance in Enterobacteriaceae, Acinetobacter and Pseudomonas aeruginosa

edited by

Ágnes Pál-Sonnevend

submission deadline 31 May 2026 | 6 articles | Viewed by 19685 | Submission Open

Keywords: gram-negative infections; mechanism of carbapenem resistance; molecular epidemiology; in vitro diagnostic tools; antimicrobial treatment; beta-lactam/beta lactamase inhibitors; cefiderocol

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Environmental Fate of Antibiotics: Monitoring, Toxicity, Resistance, and Removal Methods

edited by

Takashi Azuma

submission deadline 31 May 2026 | 8 articles | Viewed by 17725 | Submission Open

Keywords: antimicrobials; high-throughput analysis; wastewater treatment plant (WWTP); hospital wastewater; livestock environment; water purification plant (WTP); aquatic environment; environmental health risk assessment; antimicrobial resistance (AMR); advanced water treatment

Insights into Natural Antimicrobial Peptides

edited by

András Fodor

Eustachio Tarasco

and

Maurizio Francesco Brivio

submission deadline 31 May 2026 | 4 articles | Viewed by 16381 | Submission Open

Keywords: antibacterial host defense peptides; antibacterial mode of action; defensins; cathelicidins; insect antimicrobial peptides; plant antimicrobial peptides

(This special issue belongs to the Section Antimicrobial Peptides)

Antibiotic Residues, Antimicrobial Resistance and Intervention Strategies of Foodborne Pathogens, 2nd Edition

edited by

Yongning Wu

and

Zhenling Zeng

submission deadline 31 May 2026 | 4 articles | Viewed by 12301 | Submission Open

Keywords: antibiotic residues; antibiotic resistance genes; antimicrobial resistance; food safety; foodborne pathogen; intervention strategies; one health

A One Health Approach to Antimicrobial Resistance, 2nd Edition

edited by

Beatriz Robredo

submission deadline 31 May 2026 | 6 articles | Viewed by 11781 | Submission Open

Keywords: One Health; antibiotic; antimicrobial resistance; animal; food; environment

Therapy of Infectious Diseases Among Children and Adults: The Role of Antibiotics in Daily Practice

edited by

Magdalena Baymakova

and

Valeri R. Velev

submission deadline 31 May 2026 | 6 articles | Viewed by 10346 | Submission Open

Keywords: аntibiotic use among children; аntibiotic use among adults; аntibiotic use among outpatients; аntibiotic use among inpatients; antibiotic resistance; improper antibiotic use; antibiotic quality control

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Molecular Epidemiology and Mechanisms of Carbapenem Resistance in Clinical Gram-Negative Bacteria

edited by

Ángel Rodríguez-Villodres

and José Manuel Ortiz De La Rosa

submission deadline 31 May 2026 | 4 articles | Viewed by 9035 | Submission Open

Keywords: carbapenem resistance; Enterobacterales; Pseudomonas aeruginosa; Acinetobacter baumannii; molecular epidemiology

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Emerging Topics in Clostridioides difficile Infection: A One Health Problem

edited by

Simon D. Baines

submission deadline 31 May 2026 | 4 articles | Viewed by 8948 | Submission Open

Keywords: clostridium difficile infection (CDI); antimicrobial resistance (AMR); antimicrobial prescribing; one health; laboratory studies

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Revolutionizing Infection Treatment: Cutting-Edge Approaches in Antimicrobial Stewardship

edited by Jacob Myles Keck and

Aleksandra Barac

submission deadline 31 May 2026 | 5 articles | Viewed by 7969 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; infection treatment optimization; rapid diagnostics; technology in healthcare

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Optimizing Antimicrobial Therapy in NICU Settings: Strategies and Implications

edited by

Elias Iosifidis

and

Angeliki Kontou

submission deadline 31 May 2026 | 2 articles | Viewed by 6084 | Submission Open

Keywords: neonatal ICU; antimicrobial stewardship; antimicrobial resistance; neonatal sepsis; biomarkers

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 3rd Edition

edited by

Juan Manuel Vázquez-Lago

Ana Estany-Gestal

and

Angel Salgado-Barreira

submission deadline 31 May 2026 | 1 articles | Viewed by 5389 | Submission Open

Keywords: epidemiology; social behavior; antibiotic resistance; social factors; attitudes; knowledge; practice; qualitative research; public health interventions; antibiotic prescription; community care

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Bioactives from Invertebrates

edited by

Beatriz Vázquez Belda

submission deadline 31 May 2026 | 1 articles | Viewed by 4039 | Submission Open

Keywords: invertebrates; bioactive compounds; antimicrobials; antibacterial activity; marine invertebrates; insects; worms; crustaceans; mollusks

(This special issue belongs to the Section Novel Antimicrobial Agents)

Fungal Metabolites and Synthetic Derivatives: Antimicrobial Properties Toward Microbial Pathogens

edited by

João Vicente Braga De Souza

submission deadline 31 May 2026 | 2 articles | Viewed by 3528 | Submission Open

Keywords: antimicrobial resistance; fungal metabolites; synthetic derivatives; antifungal agents; bioactive compounds

(This special issue belongs to the Section Fungi and Their Metabolites)

Periprosthetic Joint Infection: Understanding the Epidemiology, Pathogenesis, Diagnosis and Treatment Options

edited by Saad Tarabichi, Mark J. Spangehl and Joshua S. Bingham

submission deadline 31 May 2026 | 2 articles | Viewed by 2986 | Submission Open

Keywords: periprosthetic joint infection; diagnosis; epidemiology; pathogenesis; treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Essential Oils as Natural Antimicrobials: Extraction, Characterization, and Synergistic Applications

edited by

Sergio A. Rodríguez

, Axel Hollmann and

Douglas Siqueira de Almeida Chaves

submission deadline 31 May 2026 | 2 articles | Viewed by 2781 | Submission Open

Keywords: natural antimicrobials; biofilm eradication; mechanism of action; synergism; antagonism; cytotoxicity; compound isolation; membrane interaction; enzymatic inhibition; DNA interaction; oxidative stress

(This special issue belongs to the Section Plant-Derived Antibiotics)

Structure and Function of Antimicrobial Peptides

edited by Daniel Balleza and

Gill Diamond

submission deadline 31 May 2026 | 1 articles | Viewed by 2431 | Submission Open

Keywords: antimicrobial peptides; natural peptides; lipidomics; synergistic action; bioactivity mechanisms; structure reconfiguration

(This special issue belongs to the Section Antimicrobial Peptides)

The Discovery of Novel Antimicrobial Agents to Combat Infections

edited by

Yuanpu Peter Di

submission deadline 31 May 2026 | 1 articles | Viewed by 2047 | Submission Open

Keywords: antimicrobials; resistance; bacteriophage; virulence; structure; PD/PK; bacteria; virus; fungus

(This special issue belongs to the Section Novel Antimicrobial Agents)

Displaying special issue 151-200 on page 4 of 7.

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