Global Strategies for Antimicrobial Stewardship: Insights from WHO and PAHO

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 1291

Special Issue Editors


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Guest Editor
CUFAR- Pharmacology Research Center, CONICET—FCMLP- PAHO_WHO, Universidad Nacional de La Plata, 60 & 120, La Plata 1900, Argentina
Interests: antimicrobials; resistance; stewardship; consumption

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Guest Editor
National University of Buenos Aires–Hospital Durand, CABA, Buenos Aires, Argentina
Interests: stewardship; antibiotics; resistance

Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) is closely linked to the levels of antimicrobial consumption/use (AMU) in each health institution or in geographical areas, and to the measures taken by local authorities to mitigate these resistance problems. In order to know the results obtained through actions towards AMR-AMU control, including antimicrobial stewardship performed in different countries, and to consider how access and shortages might affect AMU surveillance conducted by the WHO, we call for scientific contributions to this journal issue.

This Special Issue seeks to gather valuable insights and experiences from around the world, particularly those influenced by organizations such as the World Health Organization (WHO) and the Pan American Health Organization (PAHO). We invite health professionals, researchers, and policymakers to contribute their perspectives through the submission of reviews, research papers, and communications.

We welcome contributions that explore the following themes:

  1. Innovative Antimicrobial Stewardship Programs: Highlighting successful AMS initiatives in diverse healthcare environments.
  2. Surveillance Insights: Presenting data-driven analyses on AMU and AMR trends as reported by the WHO, PAHO, and other organizations.
  3. Policy Development: Offering recommendations for the formulation and implementation of effective AMS policies based on best practices and surveillance findings.
  4. Global Collaborations: Sharing experiences that illustrate how international partnerships can enhance AMS efforts and address the challenges of AMR.

We look forward to your submissions and to advancing the conversation on antimicrobial stewardship and resistance on a global scale.

Dr. Gustavo Horacio Marin
Dr. Gabriel Levy-Hara
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial
  • stewardship
  • resistance
  • consumption
  • use

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Published Papers (1 paper)

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Research

20 pages, 538 KiB  
Article
Bridging the Capacity Building Gap for Antimicrobial Stewardship Implementation: Evidence from Virtual Communities of Practice in Kenya, Ghana, and Malawi
by Ana C. Barbosa de Lima, Kwame Ohene Buabeng, Mavis Sakyi, Hope Michael Chadwala, Nicole Devereaux, Collins Mitambo, Christine Mugo-Sitati, Jennifer Njuhigu, Gunturu Revathi, Emmanuel Tanui, Jutta Lehmer, Jorge Mera and Amy V. Groom
Antibiotics 2025, 14(8), 794; https://doi.org/10.3390/antibiotics14080794 - 4 Aug 2025
Viewed by 943
Abstract
Background/Objectives: Strengthening antimicrobial stewardship (AMS) programs is an invaluable intervention in the ongoing efforts to contain the threat of antimicrobial resistance (AMR), particularly in low-resource settings. This study evaluates the impact of the Telementoring, Education, and Advocacy Collaboration initiative for Health through Antimicrobial [...] Read more.
Background/Objectives: Strengthening antimicrobial stewardship (AMS) programs is an invaluable intervention in the ongoing efforts to contain the threat of antimicrobial resistance (AMR), particularly in low-resource settings. This study evaluates the impact of the Telementoring, Education, and Advocacy Collaboration initiative for Health through Antimicrobial Stewardship (TEACH AMS), which uses the virtual Extension for Community Healthcare Outcomes (ECHO) learning model to enhance AMS capacity in Kenya, Ghana, and Malawi. Methods: A mixed-methods approach was used, which included attendance data collection, facility-level assessments, post-session and follow-up surveys, as well as focus group discussions. Results: Between September 2023 and February 2025, 77 virtual learning sessions were conducted, engaging 2445 unique participants from hospital-based AMS committees and health professionals across the three countries. Participants reported significant knowledge gain, and data showed facility improvements in two core AMS areas, including the implementation of multidisciplinary ward-based interventions/communications and enhanced monitoring of antibiotic resistance patterns. Along those lines, participants reported that the program assisted them in improving prescribing and culture-based treatments, and also evidence-informed antibiotic selection. The evidence of implementing ward-based interventions was further stressed in focus group discussions, as well as other strengthened practices like point-prevalence surveys, and development or revision of stewardship policies. Substantial improvements in microbiology services were also shared by participants, particularly in Malawi. Other practices mentioned were strengthened multidisciplinary communication, infection prevention efforts, and education of patients and the community. Conclusions: Our findings suggest that a virtual case-based learning educational intervention, providing structured and tailored AMS capacity building, can drive behavior change and strengthen healthcare systems in low resource settings. Future efforts should aim to scale up the engagements and sustain improvements to further strengthen AMS capacity. Full article
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