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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antimicrobial Resistance and Infections in Animals

edited by

John B. Kaneene

submission deadline 10 May 2026 | 9 articles | Viewed by 25136 | Submission Open

Keywords: antimicrobial resistance; mechanisms; humane and societal concerns; risk factors

(This special issue belongs to the Section Antibiotics in Animal Health)

Biotechnological Production of Novel Antimicrobials

edited by

Vanja Vlajkov

Jovana Grahovac

and

Ivana Danilov

submission deadline 15 May 2026 | 1 articles | Viewed by 2652 | Submission Open

Keywords: antibiotic resistance; biotechnology; antimicrobial activity; disease outbreak; pathogens; microorganisms; genetic engineering; artificial intelligence; optimisation; biocontrol

A Themed Issue in Honor of Professor Helen Giamarellou—Outstanding Contributions in the Fields of Antimicrobial Resistance and Difficult-to-Treat Resistance Pathogens

edited by Konstantinos Pontikis

submission deadline 20 May 2026 | 6 articles | Viewed by 34954 | Submission Open

Keywords: antibiotic stewardship; nosocomial infections; infection control; epidemiology of resistance plus in vitro investigation of underlying resistance mechanisms; infections in the ICU; neutropenic host infections; indicated therapeutic approach of MDR and XDR gram-negative infections; pharmacokinetics/pharmacodynamics of newer antimicrobial agents

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Evidence-Based Pharmaceutical Care and Rational Antibiotic Use

edited by

Suodi Zhai

and Siyan Zhan

submission deadline 20 May 2026 | Viewed by 317 | Submission Open

Keywords: rational antibiotic use; bacterial resistance; medical institutions; optimization of antibiotic usage and dosages; prescription

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Stewardship in Neonatal Intensive Care

edited by Chiara Poggi

submission deadline 30 May 2026 | 2 articles | Viewed by 2030 | Submission Open

Keywords: neonatal sepsis; early onset sepsis; late onset sepsis; preterm; antimicrobial stewardship; neonatal intensive care; molecular diagnosis; stopping rule; therapeutic drug monitoring; extended antimicrobial infusion; continuous antimicrobial infusion; microbiological surveillance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Innovative and Translational Antibiosis Approaches to Tackling Protozoan Parasites: Synergy, Drug Repurposing, Natural Products, Molecular Targets, and Therapeutic Design

edited by

Leonardo Acuña

submission deadline 30 May 2026 | 1 articles | Viewed by 1479 | Submission Open

Keywords: drug repurposing for neglected tropical diseases; natural products with antiparasitic activity; synergistic drug combinations; molecular targets and mechanisms of action

Antibiotic Prescribing in Primary Dental Care—2nd Edition

edited by

Kristina Peros

submission deadline 30 May 2026 | 1 articles | Viewed by 580 | Submission Open

Keywords: primary dental care; antibiotic prescribing; rational drug prescribing; antibiotic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiofilm Activity against Multidrug-Resistant Pathogens

edited by

Verica Aleksic Sabo

and Petar Knezevic

submission deadline 31 May 2026 | 9 articles | Viewed by 32292 | Submission Open

Keywords: biofilm; microbial drug resistance; antibiofilm agents; antibiofilm strategies; synergistic interactions

(This special issue belongs to the Section Antibiofilm Strategies)

Mechanism of Carbapenem Resistance in Enterobacteriaceae, Acinetobacter and Pseudomonas aeruginosa

edited by

Ágnes Pál-Sonnevend

submission deadline 31 May 2026 | 6 articles | Viewed by 25285 | Submission Open

Keywords: gram-negative infections; mechanism of carbapenem resistance; molecular epidemiology; in vitro diagnostic tools; antimicrobial treatment; beta-lactam/beta lactamase inhibitors; cefiderocol

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Environmental Fate of Antibiotics: Monitoring, Toxicity, Resistance, and Removal Methods

edited by

Takashi Azuma

submission deadline 31 May 2026 | 8 articles | Viewed by 22274 | Submission Open

Keywords: antimicrobials; high-throughput analysis; wastewater treatment plant (WWTP); hospital wastewater; livestock environment; water purification plant (WTP); aquatic environment; environmental health risk assessment; antimicrobial resistance (AMR); advanced water treatment

Therapy of Infectious Diseases Among Children and Adults: The Role of Antibiotics in Daily Practice

edited by

Magdalena Baymakova

and

Valeri R. Velev

submission deadline 31 May 2026 | 15 articles | Viewed by 21006 | Submission Open

Keywords: аntibiotic use among children; аntibiotic use among adults; аntibiotic use among outpatients; аntibiotic use among inpatients; antibiotic resistance; improper antibiotic use; antibiotic quality control

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Insights into Natural Antimicrobial Peptides

edited by

András Fodor

Eustachio Tarasco

and

Maurizio Francesco Brivio

submission deadline 31 May 2026 | 4 articles | Viewed by 18408 | Submission Open

Keywords: antibacterial host defense peptides; antibacterial mode of action; defensins; cathelicidins; insect antimicrobial peptides; plant antimicrobial peptides

(This special issue belongs to the Section Antimicrobial Peptides)

Antibiotic Residues, Antimicrobial Resistance and Intervention Strategies of Foodborne Pathogens, 2nd Edition

edited by

Yongning Wu

and

Zhenling Zeng

submission deadline 31 May 2026 | 6 articles | Viewed by 15807 | Submission Open

Keywords: antibiotic residues; antibiotic resistance genes; antimicrobial resistance; food safety; foodborne pathogen; intervention strategies; one health

A One Health Approach to Antimicrobial Resistance, 2nd Edition

edited by

Beatriz Robredo

submission deadline 31 May 2026 | 7 articles | Viewed by 15686 | Submission Open

Keywords: One Health; antibiotic; antimicrobial resistance; animal; food; environment

Revolutionizing Infection Treatment: Cutting-Edge Approaches in Antimicrobial Stewardship

edited by Jacob Myles Keck and

Aleksandra Barac

submission deadline 31 May 2026 | 5 articles | Viewed by 12635 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; infection treatment optimization; rapid diagnostics; technology in healthcare

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Emerging Topics in Clostridioides difficile Infection: A One Health Problem

edited by

Simon D. Baines

submission deadline 31 May 2026 | 4 articles | Viewed by 11471 | Submission Open

Keywords: clostridium difficile infection (CDI); antimicrobial resistance (AMR); antimicrobial prescribing; one health; laboratory studies

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Molecular Epidemiology and Mechanisms of Carbapenem Resistance in Clinical Gram-Negative Bacteria

edited by

Ángel Rodríguez-Villodres

and José Manuel Ortiz De La Rosa

submission deadline 31 May 2026 | 5 articles | Viewed by 11266 | Submission Open

Keywords: carbapenem resistance; Enterobacterales; Pseudomonas aeruginosa; Acinetobacter baumannii; molecular epidemiology

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 3rd Edition

edited by

Juan Manuel Vázquez-Lago

Ana Estany-Gestal

and

Angel Salgado-Barreira

submission deadline 31 May 2026 | 2 articles | Viewed by 7867 | Submission Open

Keywords: epidemiology; social behavior; antibiotic resistance; social factors; attitudes; knowledge; practice; qualitative research; public health interventions; antibiotic prescription; community care

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Optimizing Antimicrobial Therapy in NICU Settings: Strategies and Implications

edited by

Elias Iosifidis

and

Angeliki Kontou

submission deadline 31 May 2026 | 2 articles | Viewed by 7480 | Submission Open

Keywords: neonatal ICU; antimicrobial stewardship; antimicrobial resistance; neonatal sepsis; biomarkers

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Bioactives from Invertebrates

edited by

Beatriz Vázquez Belda

submission deadline 31 May 2026 | 1 articles | Viewed by 5387 | Submission Open

Keywords: invertebrates; bioactive compounds; antimicrobials; antibacterial activity; marine invertebrates; insects; worms; crustaceans; mollusks

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Resistance in Bacterial Isolates of Animal Origin

edited by

Tomasz Jarzembowski

and

Lidia Piechowicz

submission deadline 31 May 2026 | 6 articles | Viewed by 4962 | Submission Open

Keywords: zoonotic infection; resistance genes; “ one health concept” ; Salmonella enterica; Campylobacter jejuni; enterohemorrhagic Escherichia coli; Enterococcus faecalis

(This special issue belongs to the Section Antibiotics in Animal Health)

Periprosthetic Joint Infection: Understanding the Epidemiology, Pathogenesis, Diagnosis and Treatment Options

edited by Saad Tarabichi, Mark J. Spangehl and Joshua S. Bingham

submission deadline 31 May 2026 | 3 articles | Viewed by 4918 | Submission Open

Keywords: periprosthetic joint infection; diagnosis; epidemiology; pathogenesis; treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Fungal Metabolites and Synthetic Derivatives: Antimicrobial Properties Toward Microbial Pathogens

edited by

João Vicente Braga De Souza

submission deadline 31 May 2026 | 2 articles | Viewed by 4764 | Submission Open

Keywords: antimicrobial resistance; fungal metabolites; synthetic derivatives; antifungal agents; bioactive compounds

(This special issue belongs to the Section Fungi and Their Metabolites)

Genomic Surveillance of Antimicrobial Resistance (AMR)

edited by Linzy Elton

submission deadline 31 May 2026 | 5 articles | Viewed by 4517 | Submission Open

Keywords: antimicrobial resistance; sequencing; genomics; surveillance; mobile genetic elements; multi-drug-resistant organisms; One Health; metagenomics; whole-genome sequencing

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Resistance and Antimicrobial Stewardship in Veterinary Medicine

edited by Tiana Florea,

Ilie Stelian

and

Degi Janos

submission deadline 31 May 2026 | 3 articles | Viewed by 3915 | Submission Open

Keywords: antimicrobial stewardship; antibiotics; animals; sustainability; drugs; antimicrobial resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Essential Oils as Natural Antimicrobials: Extraction, Characterization, and Synergistic Applications

edited by

Sergio A. Rodríguez

, Axel Hollmann and

Douglas Siqueira de Almeida Chaves

submission deadline 31 May 2026 | 2 articles | Viewed by 3773 | Submission Open

Keywords: natural antimicrobials; biofilm eradication; mechanism of action; synergism; antagonism; cytotoxicity; compound isolation; membrane interaction; enzymatic inhibition; DNA interaction; oxidative stress

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial Resistance and Intervention Strategies in Intestinal Pathogens: A One Health Approach

edited by Gaetano Iaquinto

submission deadline 31 May 2026 | 1 articles | Viewed by 3480 | Submission Open

Keywords: epidemiology; antimicrobial resistance; multi-drug resistance; immunomodulatory activity; cytokines; gut microbiota; new antibiotics research; new vaccines; faecal microbiota transplantation; infection prevention

Animal-Origin Bacteria: Diversity, Pathogenicity and Antimicrobial Resistance

edited by

Juliana Menezes

Joana Moreira da Silva

and

Adriana Belas

submission deadline 31 May 2026 | 3 articles | Viewed by 3429 | Submission Open

Keywords: AMR; virulence; bacteria; zoonosis; companion animals; alternative therapy; food-producing animals; exotic animals; wildlife; One Health

The Discovery of Novel Antimicrobial Agents to Combat Infections

edited by

Yuanpu Peter Di

submission deadline 31 May 2026 | 1 articles | Viewed by 3079 | Submission Open

Keywords: antimicrobials; resistance; bacteriophage; virulence; structure; PD/PK; bacteria; virus; fungus

(This special issue belongs to the Section Novel Antimicrobial Agents)

Challenges of Antibiotic Resistance: Biofilms and Anti-Biofilm Agents

edited by

María Melissa Gutiérrez-Pacheco

and

Luis Alberto Ortega-Ramirez

submission deadline 31 May 2026 | 3 articles | Viewed by 3002 | Submission Open

Keywords: antibiotic resistance; biofilms; quorum sensing; virulence factors; resistance mechanisms; antibiofilm agents; natural compounds; synthetic drugs

(This special issue belongs to the Section Antibiofilm Strategies)

ESKAPEE: Mechanisms, Spread, and Evolution of Antimicrobial Resistance

edited by Ning Dong and Yarong Wu

submission deadline 31 May 2026 | 1 articles | Viewed by 2051 | Submission Open

Keywords: ESKAPE pathogens; antimicrobial resistance; genomic epidemiology

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Peptides (AMPs) Against Human Pathogens

edited by

Pedro Souza

submission deadline 31 May 2026 | 2 articles | Viewed by 1919 | Submission Open

Keywords: antimicrobial peptides (AMPs); mechanisms; structure– function relationships; synthetic and bioengineered peptides

(This special issue belongs to the Section Antimicrobial Peptides)

Antimicrobial Resistance in Veterinary Pathogens: Phenotypic Surveillance, Genomic Epidemiology, and Control Measures

edited by

Ádám Kerek

and

Ákos Jerzsele

submission deadline 31 May 2026 | 2 articles | Viewed by 1828 | Submission Open

Keywords: antimicrobial resistance; veterinary pathogens; phenotypic surveillance; genomic epidemiology; resistance genes; alternative control strategies; One Health

Molecular Epidemiology and Antibiotic Resistance in MRSA: Recent Advances in Surveillance and Control

edited by

Jae-Seok Kim

submission deadline 31 May 2026 | 1 articles | Viewed by 1631 | Submission Open

Keywords: Staphylococcus aureus; methicillin-resistant S. aureus (MRSA); hospital-associated MRSA (HA-MRSA); antimicrobial resistance; molecular epidemiology; evolution of resistance; surveillance

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Resistance and Evolving Biology in Mycobacteria: Multidisciplinarity as a Contemporary Approach

edited by

Irena Arandjelovic

and Dragana Vukovic

submission deadline 31 May 2026 | 1 articles | Viewed by 1544 | Submission Open

Keywords: tuberculosis; drug resistance; evolutionary biology; pathogen-host interactions

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Activity of Natural Products and Plants Extracts, 2nd Edition

edited by

Mihaela Niculae

and

Daniela Hanganu

submission deadline 31 May 2026 | 1 articles | Viewed by 1466 | Submission Open

Keywords: natural products; plant extracts; bioactive compounds; phytoconstituents; antibacterial efficacy; in vitro screening; in vivo evaluation; antibiofilm; anti-quorum

(This special issue belongs to the Section Plant-Derived Antibiotics)

Rethinking Mild Infections: The Role of Natural Products in Antimicrobial Stewardship

edited by

Karel Kostev

submission deadline 31 May 2026 | 1 articles | Viewed by 1133 | Submission Open

Keywords: natural products; herbal products; phytopharmaceutical; antimicrobial resistance; respiratory tract infections; urinary tract infections

Antibiotic Resistance Genes: Mechanisms, Evolution and Dissemination

edited by

Ivo Nikolaev Sirakov

and

Slawomir Ciesielski

submission deadline 31 May 2026 | 3 articles | Viewed by 990 | Submission Open

Keywords: antibiotic resistance genes; transposons; integrons; gene transfer; therapy

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

The Use of Systemic and Topical Antibiotics in Dentistry: Challenges and Future Perspectives

edited by

Sigrun Eick

and

Valentino Natoli

submission deadline 31 May 2026 | Viewed by 365 | Submission Open

Keywords: antibiotics; apical abscess; apical periodontitis; endodontic infection; periapical disease; mouth diseases; topical antibiotics; antimicrobial approaches

Antimicrobial Activity of Medical Materials, 2nd Edition

edited by Tânia Grainha and Susana Lopes

submission deadline 31 May 2026 | Viewed by 337 | Submission Open

Keywords: antimicrobial surfaces; copper; silver; surface functionalization/modifications; biofilm prevention; medical textiles; efficiency

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Antimicrobial Resistance in Animals and Animal Products and Its Environmental Transmission Aspects, Second Edition

edited by

Nikolaos Solomakos

Thomai Lazou

and

Andreana Pexara

submission deadline 31 May 2026 | Viewed by 244 | Submission Open

Keywords: antimicrobial resistance; One Health; AMR dissemination in the environment; antibiotics in animals; foodborne pathogens; animal products

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Nanomaterials: Advances, Challenges, and Future Perspectives

edited by

Nuno Miguel Figueiredo

and Daniela Santo

submission deadline 31 May 2026 | Viewed by 224 | Submission Open

Keywords: antimicrobial nanomaterials; metal and metal oxide nanoparticles and nanocomposites; carbon-based nanomaterials; polymeric and hybrid nanostructures; photocatalytic nanomaterials; multifunctional antimicrobial coatings; antimicrobial mechanisms of action; biocompatibility and toxicity

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Antimicrobial Therapeutics for Bone and Periprosthetic Joint Infection, 2nd Edition

edited by

Éric M. Senneville

submission deadline 31 May 2026 | Viewed by 187 | Submission Open

Keywords: osteomyelitis; diabetic foot osteomyelitis; periprosthetic joint infections; antimicrobial therapy; recurrence; persistence; biofilm

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

The Emerging Threat of Drug Resistance in Fungal Pathogens: Challenges and Management

edited by

Anil Mathew Tharappel

submission deadline 1 Jun 2026 | Viewed by 173 | Submission Open

Keywords: drug resistance; antifungal; fungal diseases; aspergillosis; cryptococcosis; candidiasis

(This special issue belongs to the Section Fungi and Their Metabolites)

The Antimicrobial Activity of Metal-Based Nanoparticles

edited by Suzan Pantaroto de Vasconcellos

submission deadline 10 Jun 2026 | 2 articles | Viewed by 4418 | Submission Open

Keywords: metal-nanoparticle; microbicide; virucide; phytopathogens; disinfectant; synthesis; antibiotic resistance

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Antimicrobial Resistance in Veterinary Science, 2nd Edition

edited by

Nahla O. Eltai

submission deadline 15 Jun 2026 | 7 articles | Viewed by 13058 | Submission Open

Keywords: AMR; veterinary animals; farm animals; food animals; wild animals; resistance

(This special issue belongs to the Section Antibiotics in Animal Health)

New Insights Toward the Development of Novel Inhibitors of S. aureus and P. aeruginosa Factors

edited by Que Chi Truong-Bolduc, Leon G. Leanse,

Hidemasa Nakaminami

and

Chun-Hsing Liao

submission deadline 15 Jun 2026 | 4 articles | Viewed by 5223 | Submission Open

Keywords: MSSA; MRSA; P. aeruginosa; coinfection; antibiotic resistance; therapeutic strategy; anti-virulence; quorum-sensing; virulence factors; biofilms

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Therapy in Oral Diseases, 2nd Edition

edited by

Alexandra Roman

and

Andrada Soanca

submission deadline 15 Jun 2026 | Viewed by 170 | Submission Open

Keywords: oral; antibiotic; antiseptic; tooth; periodontium; dental caries; implant; healing; cell; biomaterials; periodontitis; biocompatibility; toxicity; periodontology; periodontal pocket; bacteria; nonsurgical treatment; oral surgery; clinical trial

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

A Themed Issue in Honor of Professor Matthew E. Falagas: Antimicrobial Resistance and the Treatment of Complex Infections

edited by

Drosos E. Karageorgopoulos

submission deadline 16 Jun 2026 | 1 articles | Viewed by 1602 | Submission Open

Keywords: Acinetobacter baumannii; antimicrobial resistance; aztreonam– avibactam; carbapenemase; cefiderocol; colistin; Enterobacterales; fosfomycin; Klebsiella pneumonia; metallo β -lactamase; Pseudomonas aeruginosa

Antimicrobials Agents: Latest Advances and Prospects

edited by

Marius Stefan

submission deadline 30 Jun 2026 | 8 articles | Viewed by 41072 | Submission Open

Keywords: multidrug-resistant pathogens; infectious diseases; antibiotic resistance; new antimicrobials; drug development; antimicrobial activity; structure– activity relationship (SAR); antimicrobial therapy

(This special issue belongs to the Section Novel Antimicrobial Agents)

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