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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Discovery and Design of New Antimicrobial Agents

edited by

Jean Michel Brunel

submission deadline 5 Aug 2025 | 3 articles | Viewed by 6943 | Submission Open

Keywords: antimicrobial agents; fight resistance; new design; structure– activity relationships (SAR)

(This special issue belongs to the Section Novel Antimicrobial Agents)

Natural Alternatives and Their Synthetic Derivatives to Antibiotics

edited by

Simone Carradori

submission deadline 15 Aug 2025 | 3 articles | Viewed by 10655 | Submission Open

Keywords: antibacterial agents; quorum sensing inhibitors; food contamination and preservation; innovative (micro)extraction procedures; synthetic derivatives inspired by natural scaffolds; uses of components from medicinal plants and fungi; biofilm and antimicrobial resistance

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms, 3rd Edition

edited by

Anna Duda-Madej

Joanna Kozłowska

and

Katarzyna Wińska

submission deadline 15 Aug 2025 | Viewed by 198 | Submission Open

Keywords: antimicrobial activity; plant extracts; plant-derived compounds; synthetic derivatives; flavonoids; multidrug resistance; pathogenic strains

(This special issue belongs to the Section Plant-Derived Antibiotics)

Prevalence and Antibiotic Resistance of Mycobacterium tuberculosis

edited by

Chongguang Yang

submission deadline 20 Aug 2025 | 1 articles | Viewed by 714 | Submission Open

Keywords: Mycobacterium tuberculosis; prevalence; antimicrobial resistance; multidrug-resistance; tuberculosis; molecular epidemiology

Origins and Evolution of Antibiotic Resistance in the Environment

edited by

Damian Rolbiecki

and

Małgorzata Czatzkowska

submission deadline 20 Aug 2025 | 1 articles | Viewed by 268 | Submission Open

Keywords: surface water; soil; wastewater; antibiotic resistance genes; antibiotic resistant bacteria; One Health; WHO pathogens; anthropogenic pressure

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Progress and Challenges in the Antibiotic Treatment of Infections

edited by Marina Bubonja-Sonje

submission deadline 24 Aug 2025 | 2 articles | Viewed by 1918 | Submission Open

Keywords: antimicrobial therapy; antimicrobial stewardship; antimicrobial resistance; rapid microbiological diagnostics

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Use and Antimicrobial Stewardship for Children in the Emergency Department

edited by

Michael Barrett

and

Spyridon Karageorgos

submission deadline 31 Aug 2025 | 7 articles | Viewed by 33290 | Submission Open

Keywords: pediatric ED; ambulatory; antimicrobial stewardship; antibiotic use; antimicrobial resistance; point-of-care testing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobials Use: Clinical Safety to Environmental Risk—Learning from One Health Approach

edited by

Anabela Almeida

Leonor M. Meisel

and

Ana Fortuna

submission deadline 31 Aug 2025 | 7 articles | Viewed by 31282 | Submission Open

Keywords: antimicrobials; antifungals; antiviral; environment; antimicrobial resistance; pharmacokinetics; risk-assessment; prioritisation; One-Health

Antimicrobial Activity of Secondary Metabolites Produced in Nature

edited by

Dragana Božić

and

Mirjana D. Marčetić

submission deadline 31 Aug 2025 | 10 articles | Viewed by 29086 | Submission Open

Keywords: antimicrobial resistance; multidrug-resistant pathogens; secondary metabolites; natural products; terpenes; phenolic compounds; polyketides; antimicrobial peptides; bacteriocins; bacterial/fungal toxins

(This special issue belongs to the Section Plant-Derived Antibiotics)

Membranes to Fight Drug-Resistant Microbes

edited by

Nermina Malanovic

submission deadline 31 Aug 2025 | 6 articles | Viewed by 18325 | Submission Open

Keywords: antimicrobial peptides; membrane-active compounds; mode of action; lipidoids; vaccines

(This special issue belongs to the Section Antimicrobial Peptides)

From Detection to Treatment: Navigating Urinary Tract Infections with Antibiotics

edited by

Eleonora Nicolai

submission deadline 31 Aug 2025 | 4 articles | Viewed by 14708 | Submission Open

Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria

edited by

Daniel Gyamfi Amoako

and

Linda Bester

submission deadline 31 Aug 2025 | 9 articles | Viewed by 13009 | Submission Open

Keywords: antimicrobial resistance mechanism; mobile genetic element; horizontal gene transfer; resistome; evolution; molecular phylogenetics; genomics; bioinformatics analysis; next-generation sequencing

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Healthcare-Associated Infections (HAIs): Prevention, Control and Surveillance

edited by

Maria Bagattini

submission deadline 31 Aug 2025 | 6 articles | Viewed by 10169 | Submission Open

Keywords: healthcare-associated infections (HAIs); infection prevention and control; antimicrobial resistance; HAIs management and control; carbapenem resistant (CR) Enterobacterales; carbapenem resistant (CR) Acinetobacter baumannii

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Bacterial Resistome and Antimicrobial Resistance in Animal Infectious Diseases

edited by

Paolo Capozza

Nicola Pugliese

and

Maria Tempesta

submission deadline 31 Aug 2025 | 1 articles | Viewed by 7497 | Submission Open

Keywords: bacterial resistome; antimicrobial resistance; animal Infectious diseases; veterinary medicine

(This special issue belongs to the Section Antibiotics in Animal Health)

Antibiotics: Fighting Disease and Promoting Health by Embracing the Two Sides of the Same Coin

edited by

Chrysoula Voidarou

Elisavet Stavropoulou

and

Eugenia Bezirtzoglou

submission deadline 31 Aug 2025 | 2 articles | Viewed by 6876 | Submission Open

Keywords: antibiotics; probiotics; antibacterial activity; functional food; natural compounds; natural antimicrobials; microbiome; antimicrobial resistance; resistome

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Antimicrobial Applications of Green Nanotechnology in Biomedicine and the Environment

edited by

María Gabriela Paraje

, Maria Teresa A. Alvarez Aliaga, Natalia Lorena Guiñazú and

Fernando Gomes de Souza Junior

submission deadline 31 Aug 2025 | 1 articles | Viewed by 5380 | Submission Open

Keywords: green nanoparticles; eco-friendly synthesis; antimicrobial activity; anti-biofilm strategies; antimicrobial resistance; synergistic effects; drug delivery systems; nanotoxicity; sustainable nanotechnology; environmental applications; one health approach

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Activity of Extracts from Plants, 2nd Edition

edited by

Lucia Recinella

and

Sheila Leone

submission deadline 31 Aug 2025 | 2 articles | Viewed by 5097 | Submission Open

Keywords: antimicrobial activity; metabolomic fingerprint; bioinformatics

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Resistance in Hospital-Acquired Infections

edited by Andreea-Loredana Golli,

Ovidiu Zlatian

and

Alice Elena Ghenea

submission deadline 31 Aug 2025 | 2 articles | Viewed by 3358 | Submission Open

Keywords: healthcare-associated infections; multi-drug resistance; epidemiology; antimicrobial therapy; patient outcomes; infection prevention and control strategies

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Stewardship Implementation Strategies

edited by

Massimo Sartelli

submission deadline 31 Aug 2025 | 4 articles | Viewed by 2713 | Submission Open

Keywords: antibiotic stewardship; implementation; hospital settings

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotics and the Evolution of Resistance: Insights into Horizontal Gene Transfer

edited by

Günther Koraimann

and

Elisabeth Grohmann

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2442 | Submission Open

Keywords: antibiotic resistance spread and evolution; pathogens; one health; plasmids; integrative conjugative elements; bacteriophages; conjugative transfer; transduction

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Discovery and Development of Novel Antibacterial Agents—2nd Edition

edited by

Kui Zhu

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1679 | Submission Open

Keywords: antibiotic discovery; antibacterial target; mode of action; natural product

(This special issue belongs to the Section Novel Antimicrobial Agents)

Advances in Infective Endocarditis Research: From Bench to Bedside

edited by Joya-Rita Hindy

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1483 | Submission Open

Keywords: infective endocarditis; prosthetic valve endocarditis; cardiac implantable electronic devices; recurrent infective endocarditis; valvular heart disease; cardiac surgery; molecular diagnostics; innovative drug delivery; antimicrobial resistance; suppressive therapy

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Treatment and Antibiotic Resistance of Enterococcus Infections, 2nd Edition

edited by

Giovanni Boccia

Gianluigi Franci

and

Biagio Santella

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1430 | Submission Open

Keywords: antibiotics; antimicrobial resistance; enterococcus faecium; enterococcus faecalis; drug resistance; epidemiologic studies; endocarditis

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Challenges and Strategies for the Antibiotic Resistance Crisis

edited by

Manuel Simões

and

Marc Maresca

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1273 | Submission Open

Keywords: antibiotics stewardship; antimicrobial use; antibiotics resistance; novel antimicrobial agents; multidisciplinary antimicrobial strategies; antibiotic clinical studies; artificial intelligence strategies

Antibiotic Use and Antibiotic Resistance in Dermatology

edited by

Ayman Grada

and

Christopher Bunick

submission deadline 31 Aug 2025 | Viewed by 710 | Submission Open

Keywords: antibiotics; resistance; dermatology; antimicrobial resistance; bacteria

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Advancing and Standardising Antimicrobial Susceptibility and Resistance Detection Methodology

edited by

Owen B. Spiller

submission deadline 31 Aug 2025 | 1 articles | Viewed by 687 | Submission Open

Keywords: antimicrobial susceptibility testing; resistance screening; rapid diagnostics; clinical; veterinary; environmental; validation

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Stewardship—from Projects to Standard of Care

edited by Gesche Först and Franky Buyle

submission deadline 31 Aug 2025 | 1 articles | Viewed by 527 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial use; antibiotics; implementation; efficacy; quality; antimicrobial prescribing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Multidurg Resistant Enterobacterales: Mechanisms, Epidemiology and Diagnostics

edited by José Manuel Ortiz De La Rosa and

Mustafa Sadek

submission deadline 31 Aug 2025 | Viewed by 506 | Submission Open

Keywords: multidrug-resistant Enterobacterales; dissemination; detection; β -lactamases; genomics

Ionic Liquids as Novel Antimicrobial Agents

edited by

Patrick-Julian Mester

and Tomasz Cłapa

submission deadline 31 Aug 2025 | Viewed by 400 | Submission Open

Keywords: ionic liquids; antimicrobials; biocides; bacteria; fungi; viruses; structure– activity relationship

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotics for Primary Care Practice

edited by Reza Nassiri

submission deadline 31 Aug 2025 | Viewed by 336 | Submission Open

Keywords: primary care practice; nursing home practice; remote practice; antibiotic prescription habits; antibiotic resistance in clinical practice; public health consequences of antibiotic resistance; antibiotics stewardship practices; elements of safe practice

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Novel (Bio)electroanalytical Methods and Related Outcomes of Antibiotics Determination

edited by

Mihaela Buleandrǎ

and

Dana Elena Popa

submission deadline 31 Aug 2025 | Viewed by 331 | Submission Open

Keywords: antibiotics; electrochemical (bio)sensors; electroanalysis; redox behavior; electrochemical instrumentation; modified electrodes

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Epidemiology, Drug Resistance, and Virulence in Zoonotic Pathogens

edited by

Sonsiray Alvarez-Narvaez

Laura Huber

and Susan Sanchez

submission deadline 31 Aug 2025 | Viewed by 261 | Submission Open

Keywords: antimicrobial resistance; epidemiology; molecular epidemiology; virulence; host– pathogen interactions; zoonosis; one health

(This special issue belongs to the Section Antibiotics in Animal Health)

New Inhibitors for Overcoming Antimicrobial Resistance

edited by

Humberto Medeiros Barreto

and

Sofia Santos Costa

submission deadline 31 Aug 2025 | Viewed by 175 | Submission Open

Keywords: antimicrobial resistance; resistance mechanisms; inhibitors; enzymatic inhibitors; efflux; biofilms

Urinary Tract Infections: Diagnosis, Etiology, Antibiotic Treatment, and Current Trends in Antimicrobial Resistance

edited by Michael Mihailov Petrov

submission deadline 31 Aug 2025 | Viewed by 127 | Submission Open

Keywords: urinary tract infections (UTIs); etiology; epidemiology; microbiological diagnosis; antimicrobial resistance; treatment; molecular genetic methods; resistotypes; rapid identification; uropathogens

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Global Perspectives on Antimicrobial Stewardship: Lessons from Multidisciplinary and Transdisciplinary Approaches

edited by

Gigi Lim

submission deadline 31 Aug 2025 | Viewed by 113 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; clinical expertise; public health; AI

Antimicrobial Resistance of Staphylococcus spp. in Animals: A One Health Perspective

edited by Gi Yong Lee

submission deadline 5 Sep 2025 | Viewed by 170 | Submission Open

Keywords: staphylococci; molecular epidemiology; antimicrobial resistance; One Health; multiomics

(This special issue belongs to the Section Antibiotics in Animal Health)

Strategies to Counteract Mono- and Polymicrobial Biofilm-Related Infections

edited by

Giovanni Di Bonaventura

submission deadline 10 Sep 2025 | 1 articles | Viewed by 1186 | Submission Open

Keywords: antimicrobials; anti-biofilm; biofilm control; biofilm-associated infections

(This special issue belongs to the Section Antibiofilm Strategies)

Pharmacologic Management of MDR Respiratory and Bacteraemic Infections

edited by

Demosthènes A. Makris

and Konstantinos D. Mantzarlis

submission deadline 15 Sep 2025 | Viewed by 381 | Submission Open

Keywords: pneumonia; bacteraemia; intensive care; MDR infections; antibiotics

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Discovery and Development of the Novel Antimicrobial Agent—2nd Volume

edited by

Zeinab Khalil

submission deadline 15 Sep 2025 | Viewed by 279 | Submission Open

Keywords: antibiotics; bacteria; fungi; plants; multidrug-resistant pathogens; natural products; mode of action; mechanism of action; drug target; drug development

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Resistance in the Era of Climate Change

edited by

Natalia G. Vallianou

and Eleni Geladari

submission deadline 15 Sep 2025 | Viewed by 249 | Submission Open

Keywords: climate change; extremes in temperature; antimicrobial resistance (AMR)

Nanomaterials in Oral Health: Novel Antimicrobial Treatments in Dentistry

edited by

Liliana Burlibasa

and

Serena Riela

submission deadline 15 Sep 2025 | Viewed by 232 | Submission Open

Keywords: nanomaterials; oral health; antimicrobial treatments; dentistry; genotoxicity

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Surveillance of Carbapenem-Resistant Microbes and Strategies to Combat Them

edited by Daniela Cejas and Marcela Radice

submission deadline 15 Sep 2025 | Viewed by 153 | Submission Open

Keywords: antibiotic resistance; epidemiology; carbapenemases; carbapenem resistance; enterobacterales; acinetobacter baumannii; resistance plasmids; surveillance; genomics; high-risk clones

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Choices for Pediatric Infections

edited by Theodouli Stergiopoulou

submission deadline 15 Sep 2025 | Viewed by 127 | Submission Open

Keywords: pediatric; neonatal infectious diseases; antimicrobial agents; antibiotic treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic-Associated Dysbiosis and Management

edited by

Yuseok Moon

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4210 | Submission Open

Keywords: dysbiosis; antibiotics; immunity; microbiota; intervention

Strategies for the Design of Hybrid-Based Antimicrobial Compounds

edited by

Vuyolwethu Khwaza

Sibusiso Alven

and

Blessing Atim Aderibigbe

submission deadline 20 Sep 2025 | 1 articles | Viewed by 961 | Submission Open

Keywords: hybrid compounds; antimicrobial agents; antibacterial agents; antifungal activity; antiviral activity; in vitro evaluation; structure– activity relationship (SAR); bioactive molecules; nanoformulations; targeted drug delivery; pharmacological screening; clinical studies

(This special issue belongs to the Section Novel Antimicrobial Agents)

Therapeutic Drug Monitoring of Antibiotics in the Hospital Environment

edited by Natalia Brucker

submission deadline 25 Sep 2025 | 2 articles | Viewed by 1699 | Submission Open

Keywords: therapeutic drug monitoring (TDM); antibiotics; hospital environment; healthcare

Plants, Lichens, Fungi, and Algae Extracts and Derivatives with Antimicrobial Properties for Nutrition and Health

edited by

Violeta Popovici

Emma Adriana Ozon

Andreea Letitia Arsene

and

Verginica Schroder

submission deadline 30 Sep 2025 | 8 articles | Viewed by 20492 | Submission Open

Keywords: antimicrobial and antibiofilm activity; plants/lichens/fungi/algae extracts and derived products with antibacterial; antifungal; antiviral; antiprotozoal and antihelmintic properties; antimicrobial metabolites: quantification and characterization; pharmaceutical formulation; in vivo and in vitro testing; essential oils with antimicrobial properties for the pharmaceutical and food industry; functional foods; plant-based diet; case studies; prevention and treatment of infectious diseases with plant-derived products

(This special issue belongs to the Section Plant-Derived Antibiotics)

State-of-the-Art in Antimicrobial Research in Greece

edited by

Paraskevi Papaioannidou

submission deadline 30 Sep 2025 | 5 articles | Viewed by 14879 | Submission Open

Keywords: antibiotics; antimicrobials; antibiotic surveillance; antimicrobial resistance; biofilms; one health

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Honey: Antimicrobial and Anti-infective Function

edited by

Niels Cremers

and

Juraj Majtan

submission deadline 30 Sep 2025 | 5 articles | Viewed by 14460 | Submission Open

Keywords: antimicrobial activity; biofilms; infections; clinical applications

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Resistance and Infections in Animals

edited by

John B. Kaneene

submission deadline 30 Sep 2025 | 5 articles | Viewed by 14119 | Submission Open

Keywords: antimicrobial resistance; mechanisms; humane and societal concerns; risk factors

(This special issue belongs to the Section Antibiotics in Animal Health)

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