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The hydroxamic acid moiety is part of many bioactive molecules, including several clinical drugs, which can be constructed through, generally, the parent carboxylic acid and a source of hydroxylamine by a variety of methods. Hydroxamic acids compose...

In this work we report the stereoselective synthesis of 2H-flavenes via an Aminocatalytic privileged Diversity-Oriented Synthesis (ApDOS) strategy. An oxa-Michael cyclization between salicylaldehydes and an iminium intermediate from cinnamaldehyde an...

In this study, a PVA/graphene oxide (GO) hydrogel nanocomposite was synthesized as a adsorbent for Li+ removal from aqueous solutions. The composite was characterized by FTIR, XRD, and SEM/EDS to verify interfacial interactions and porous morphology....

This work presents a step-by-step synthesis of a new derivative of 1,3,5-oxadiazine. In the first step, by reacting N-(1-amino-2,2,2-trichloroethyl)acetamide with 2-bromobenzoyl isothiocyanate, a previously undescribed thiourea, N-((1-acetamido-2,2,2...

This study investigates thienyl-substituted diketopyrrolopyrrole (DPP) derivatives with tailored alkyl chain modifications on the DPP core to tune molecular packing, solubility, and optoelectronic properties critical for device applications. A key ad...

This work reports progress in the semi-synthetic modification of cassane-type diterpenes isolated from Coulteria platyloba, a plant of ethnopharmacological relevance. The approach involves a sequence of transformations, including oxidative aromatizat...

This research focuses on environmental challenges and has considerable importance, as Ni, Cu, Zn, Cr, As, Hg, and Pb heavy metals pose potential hazards for plants as well as for microorganisms that are useful for plants. The binding affinity of a pr...

Introduction: Acinetobacter baumannii is a multidrug-resistant pathogen from the ESKAPE group, associated with nosocomial infections. Its resistance to multiple antibiotics poses a global threat. The QACE protein, an efflux pump, has been identified...

The synthesis and application of new chiral amino acids (AAs) and peptides derived thereof is a research topic of major importance. The introduction of γ-AA as building blocks are useful for the development of original chiral small molecules an...

CRISPR-Cas systems have transformed genome engineering with their exceptional precision, programmability, and affordability. Although they originate from microbial defense mechanisms, expanding their use, especially in therapeutics, requires a chemic...