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Separations, Volume 9, Issue 8

August 2022 - 44 articles

Cover Story: Food Contact Materials (FCMs) are an undervalued source of food contamination and a potential route of human exposure to chemicals that are harmful to the endocrine system. Food and water are the main sources of exposure due to their contact with polymeric packaging materials.
European Regulation 10/2011 on plastics in contact with food requires migration tests on FCMs to evaluate the presence of the listed substances and of not intentionally added substances (NIASs) not listed in the regulation and not subjected to restrictions. NIAS are defined as impurities present in the substances used or reaction intermediates formed during the production process, a reaction, or a product’s decomposition. The presence of NIAS in samples tested implies safety risks. The safety risks associated with these compounds must be assessed in line with internationally recognized principles on risk assessment. View this paper
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Articles (44)

  • Article
  • Open Access
7 Citations
3,502 Views
12 Pages

Aerobic granular sludge (AGS) application in treating municipal wastewater has been greatly restricted due to its low stability. It has been found that operation parameters have a great impact on stability. The organic loading rate (OLR) and dissolve...

  • Article
  • Open Access
14 Citations
2,777 Views
10 Pages

Research into Gas Chromatography–Mass Spectrometry (GC-MS) for Ensuring the Effect of 1 MeV-Accelerated Electrons on Volatile Organic Compounds in Turkey Meat

  • Ulyana Bliznyuk,
  • Polina Borshchegovskaya,
  • Timofey Bolotnik,
  • Alexander Chernyaev,
  • Victoria Ipatova,
  • Alexander Nikitchenko,
  • Oleg Shinkarev,
  • Dmitry Yurov,
  • Oleg Khmelevskiy and
  • Igor Rodin

One of the most important tasks in the food industry is the search for alternative biochemical markers of radiation treatment in dietary, chilled meat products such as chicken and turkey. Major organic volatile chemicals found in meat products can be...

  • Article
  • Open Access
5 Citations
2,189 Views
10 Pages

Preparation of Thermodesorption Tube Standards: Comparison of Usual Methods Using Accuracy Profile Evaluation

  • Clément De Saint Jores,
  • Romain Klein,
  • Agathe Legendre,
  • José Dugay,
  • Didier Thiébaut and
  • Jérôme Vial

In order to quantify organic impurities in gas produced from renewable sources, thermal desorption coupled with GC-MS or GC×GC-MS is very useful. However, the preparation of the standard tubes appears not to be trivial. For that, different stra...

  • Article
  • Open Access
2,321 Views
15 Pages

The Quality Control of Midecamycin and the Predictive Demarcation between Its Impurities and Components

  • Mingyan Yu,
  • Weijian Wang,
  • Wenkun Liu,
  • Huiru Yang,
  • Tong Sun,
  • Haiyun Zhao and
  • Dejun Chen

Midecamycin is a 16-membered macrolide antibiotic. It can inhibit the synthesis of bacterial proteins by blocking up the activity of peptidyl transferase in the 50S ribosome. We used high-resolution mass spectrometry to analyze midecamycin, and quant...

  • Review
  • Open Access
30 Citations
13,971 Views
26 Pages

An Overview of Methods for L-Dopa Extraction and Analytical Determination in Plant Matrices

  • Carmen Tesoro,
  • Filomena Lelario,
  • Rosanna Ciriello,
  • Giuliana Bianco,
  • Angela Di Capua and
  • Maria Assunta Acquavia

L-dopa is a precursor of dopamine used as the most effective symptomatic drug treatment for Parkinson’s disease. Most of the L-dopa isolated is either synthesized chemically or from natural sources, but only some plants belonging to the Fabacea...

  • Article
  • Open Access
4 Citations
2,583 Views
12 Pages

New Approach for Trace Thallium Removal in High Purity Ammonium Rhenate Solution by P204 Extraction

  • Aifei Yi,
  • Ying Liu,
  • Xingwu Lu,
  • Song Chen,
  • Honglin Jiang,
  • Chuanbing Shao,
  • Xuetao Yuan and
  • Yanxi Yin

Thallium (Tl) is an extremely toxic rare metal to the eco-environment. Trace thallium impurity in ammonium perrhenate is harmful to the high-temperature mechanical properties of rhenium metal used for aeroengine single crystal blade. The di(2-ethylhe...

  • Article
  • Open Access
4 Citations
3,840 Views
10 Pages

Unlocking the Treasure Box: The Role of HEPES Buffer in Disassembling an Uncommon Ferritin Nanoparticle

  • Alessio Incocciati,
  • Lucia Bertuccini,
  • Alberto Boffi,
  • Alberto Macone and
  • Alessandra Bonamore

Ferritins are ideal nanoparticles as drug delivery systems due to their hollow-sphere structure and the ability to target specific receptors on the cell surface. Here, we develop and characterize a new ferritin derived from the chimeric humanized A....

  • Article
  • Open Access
2 Citations
2,210 Views
9 Pages

Development and Validation of a Sensitive HPLC Assay for Determination of Sparfloxacin According to the European Medicines Agency Guideline

  • Cristina López,
  • Raquel Díez,
  • José M. Rodríguez,
  • Matilde Sierra,
  • Juan J. García,
  • Nélida Fernández,
  • M. José Diez and
  • Ana M. Sahagún

Sparfloxacin, a synthetic antibiotic belonging to the third-generation fluoroquinolones, has numerous pharmacokinetic and microbiological advantages which can make it an excellent candidate for the treatment of infections in sheep. The objective of t...

  • Article
  • Open Access
11 Citations
3,653 Views
11 Pages

Two New HPLC Methods, Assessed by GAPI, for Simultaneous Determination of Four Antipsychotics in Pharmaceutical Formulations: A Comparative Study

  • Eman A. Abdel Hameed,
  • Zaitona A. Abd El-Naby,
  • Alaa El Gindy,
  • Sawsan A. Zaitone,
  • Reem Alshaman,
  • Roshdy E. Saraya and
  • Gasser M. Khairy

Antipsychotics are widely used to treat various mental disorders. Combination therapies were approved by the FDA to treat manic states. Quetiapine fumarate, aripiprazole, asenapine maleate, and chlorpromazine HCl are frequently used for treatment of...

  • Article
  • Open Access
3 Citations
2,261 Views
11 Pages

The accumulation of rare-earth and heavy metal ions from wastewater is important for industrial technology. However, practical accumulators of metal ions are expensive with respect procurement of raw materials, synthesis, and preparation. Therefore,...

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Separations - ISSN 2297-8739