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Separations, Volume 13, Issue 4

2026 April - 26 articles

Cover Story: Spent coffee grounds are more than a residue: they are a rich matrix of phenolic compounds and proteins with strong potential for biorefinery applications. This study explores hydrophilic and hydrophobic eutectic solvents, alone or combined with enzyme-assisted extraction, as alternative media for recovering these value-added fractions. Among 31 hydrophobic eutectic solvents and nine hydrophilic deep eutectic solvents, extraction performance was highly dependent on solvent composition. Camphor:oleic acid showed the highest phenolic recovery, while its combination with Cellic® CTec2 markedly enhanced protein extraction. The results highlight eutectic solvents as tunable platforms for converting coffee waste into functional ingredients through more sustainable extraction strategies. View this paper
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Articles (26)

  • Article
  • Open Access
2 Citations
1,228 Views
25 Pages

With the increase in the demand for electronic-grade high-purity silane in the semiconductor chip industry, it is of great significance to develop a green and economical method for silane production. Therefore, a novel energy-saving fixed-bed process...

(This article belongs to the Section Separation Engineering)
  • Article
  • Open Access
947 Views
16 Pages

A water acetone biphasic extraction system was developed for the separation and purification of erythromycin thiocyanate. Response surface methodology based on a Box-Behnken design was used to evaluate the effects of pH, liquid-to-solid ratio, extrac...

(This article belongs to the Special Issue Design and Optimization of Extraction/Separation Processes for Natural Products)
  • Article
  • Open Access
1,325 Views
14 Pages

Effect of Sintering Temperature on Phase Evolution and Oil-Repellent Performance of TiO2–Carbon-Coated Stainless-Steel Mesh

  • Kayla Laguana,
  • Sonia Egenberger,
  • Jack Tobin,
  • Claudia Wong and ,
  • Logan Lu,
  • Jack G. Webster and
  • Mingheng Li
  • + 2 authors+ 0 author

This study investigates how sintering temperature affects phase evolution, titanium carbide (TiC) formation, and oil-repellent performance in TiO2–carbon-coated 304 stainless-steel mesh for oil–water separation applications. Coated meshes...

(This article belongs to the Section Separation Science in Energies)
  • Article
  • Open Access
1 Citations
833 Views
20 Pages

Moisture Reduction and Particle Charging Promotion for Enhanced Electrostatic Separation of Coal Gasification Fine Slag by Molecular Sieve

  • Chaoyong Li,
  • Hui Zhou,
  • Haisheng Li,
  • Yinghua Chen and ,
  • Ziyin Xu,
  • Jie Li,
  • Qiqiang Gao and
  • Qiang Zhao
  • + 3 authors+ 0 author

As an efficient dry separation technology, electrostatic separation exhibits significant potential for application in the sorting and recovery of carbon-rich resources from coal gasification fine slag (CGFS). The small particle size and high moisture...

(This article belongs to the Special Issue The Latest Progress in the Coal-Based Solid Waste Particle Separation)
  • Article
  • Open Access
951 Views
17 Pages

This study addresses the issue of insufficient product purity caused by the co-deposition of three major impurity ions—zinc, nickel, and lead—during the electrodeposition process of high-purity manganese. A targeted deep purification meth...

(This article belongs to the Section Separation Engineering)
  • Article
  • Open Access
792 Views
13 Pages

Extractive Purification of Sulfur and Nitrogen Fuel Contaminants Using p-Toluenesulfonic Acid-Based Deep Eutectic Solvents

  • Salim Mokraoui,
  • Lahssen El Blidi,
  • Irfan Wazeer,
  • Attiyah A. Al-Zahrani and
  • Mohamed K. Hadj-Kali

This study demonstrates the high efficiency and selectivity of p-toluenesulfonic acid-based deep eutectic solvents (DESs) for simultaneous extractive denitrogenation (EDN) and desulfurization (EDS) of model fuel. Three DESs—TBPB:PTSA, TBAB:PTSA...

(This article belongs to the Special Issue The Application of Ionic Liquids and Deep Eutectic Solvents in Separation and Extraction Processes)
  • Article
  • Open Access
1,407 Views
22 Pages

Molecularly Imprinted Polymer with Photocatalytic Activity for the Adsorption and Degradation of Naproxen and Its Application in Real Water Samples

  • Diana Samantha Villarreal-Lucio,
  • Karla Ximena Vargas-Berrones,
  • Brenda V. Loera-García,
  • Vanessa Sarahí Galván-Romero and ,
  • Carolina López-Saldaña,
  • Raúl Ocampo-Pérez,
  • Héctor Hernández-Mendoza and
  • Rogelio Flores-Ramírez
  • + 3 authors+ 0 author

This research focused on the development and characterisation of molecularly imprinted polymers (MIPs) modified with titanium dioxide (TiO2) for the adsorption and photocatalytic degradation of sodium naproxen (NPX). Different percentages of TiO2 (5%...

(This article belongs to the Special Issue Molecularly Imprinting Polymers for Separation and Detection)
  • Article
  • Open Access
1 Citations
1,370 Views
17 Pages

The efficient removal of dyes and separation from dissolved salts are crucial for the recovery of valuable resources from saline textile wastewater. In this study, hollow fiber membranes were fabricated using the non-solvent-induced phase separation...

(This article belongs to the Special Issue Membrane Separation Process for Water Treatment)
  • Article
  • Open Access
4 Citations
1,303 Views
16 Pages

This study presents a combined process of sulfide precipitation followed by hydrogen peroxide leaching for rhenium recovery from copper smelting waste acid under ambient temperature and pressure. The process first removed copper through selective sul...

(This article belongs to the Special Issue Research on Metal Resource Recycling and Efficient Extraction Technologies)
  • Article
  • Open Access
1,293 Views
22 Pages

Study on the Dewatering Mechanism of Fine Phosphate Tailings Slurrys Based on the Particle-Agent Interaction and Sedimentation Property

  • Fang Li,
  • Yuping Fan,
  • Yuanpeng Fu,
  • Xiaomin Ma and ,
  • Xianshu Dong,
  • Yangge Zhu,
  • Wei Xiao and
  • Wenjie Fang
  • + 3 authors+ 0 author

Fluorapatite is a typical phosphate rock resource. Fluorapatite tends to generate fine mud agglomeration, which induces dehydration challenges owing to its inherently fine particle size and negative surface charge. In this paper, phosphate tailings s...

(This article belongs to the Special Issue Separation Technology in Mineral Processing)
  • Article
  • Open Access
2 Citations
1,917 Views
14 Pages

Dehydration Characteristics of Viscous Fine Coal in Compound Force-Field with Vibration and Airflow

  • Jun Zhang,
  • Ming Shao,
  • Minghan Zhou,
  • Lin Zhang and ,
  • Yingguang Zuo,
  • Lijun Wang and
  • Yadong Zhang
  • + 2 authors+ 0 author

The paper utilizes the synergy of vibration and hot air flow to form a composite force field, and low-quality fine coal with viscous moisture is subjected to ash removal. The vibration signals of the bed surface at different positions are collected o...

(This article belongs to the Special Issue Research Progress of Gas–Solid Fluidized Dry Separation)
  • Article
  • Open Access
669 Views
16 Pages

Surface-modified waste scallop shells were investigated as a solid flocculant for removing suspended particles, and a light transmission method was examined as a simple approach for evaluating flocculation behavior. Kaolin suspensions (3, 5, 10 g/L,...

(This article belongs to the Section Separation Engineering)
  • Article
  • Open Access
960 Views
22 Pages

Toward Mechanism-Driven Control: A Soft-Sensor for Zeta Potential and Settling-Decisive Parameters in Coal Slime Water Treatment

  • Jing Chang,
  • Bianbian Guo,
  • Guoyu Bai,
  • Xinyuan Zhang and ,
  • Hang Zhang,
  • Wei Zhao and
  • Zhen Li
  • + 2 authors+ 0 author

Intelligent dosing in coal slime water treatment remains a challenge due to the lack of real-time and solid hardware-based measurement of key microscopic parameters governing the settling process, particularly zeta potential. This study proposes a so...

(This article belongs to the Section Purification Technology)
  • Article
  • Open Access
676 Views
19 Pages

This study aims to achieve the efficient preparation of sunflower calathide flavonoids (SCF) through optimized processes and to elucidate their composition and bioactivity. Total flavonoids were prepared by optimizing the ultra-high-pressure extracti...

(This article belongs to the Special Issue Extraction, Purification and Functional Substances of Natural Products and Plants)
  • Article
  • Open Access
606 Views
14 Pages

Flip-flow screens are widely used for the efficient separations of wet fine materials. To explore the separation characteristics of the particle and screen plate in the flip-flow screening process, a flip-flow plate impact experimental system was bui...

  • Article
  • Open Access
815 Views
19 Pages

Two mineral-based solid residues, namely coal gangue (CG) and phosphorus tailings (PT), two of the largest solid waste streams in the mining industry, were used as the sole metal feedstocks to fabricate a novel MgCaFeAl layered double hydroxide (LDH-...

(This article belongs to the Special Issue Separation Technology for Metal Extraction and Removal)
  • Article
  • Open Access
791 Views
26 Pages

As an efficient solid–liquid separation device, the hydrocyclone is widely applied in various industrial fields such as coal preparation and oil impurity removal, and its classification performance directly determines the efficiency of industri...

(This article belongs to the Section Separation Engineering)
  • Article
  • Open Access
676 Views
20 Pages

Traditional Chinese prescriptions are characterized by complex chemical constituents and wide variations in constituent content, which pose a substantial challenge to their comprehensive characterization. As a classic traditional Chinese prescription...

(This article belongs to the Topic Application of Chromatography-Mass Spectrometry and Related Techniques, 2nd Edition)
  • Article
  • Open Access
1,100 Views
14 Pages

Selective HCl Separation from HCl/SiF4 Mixtures via Glycerol-Based Absorption and Staged Vacuum Desorption

  • Panpan Chu,
  • Qihan Wang,
  • Fan Yang,
  • Guangpeng Chen and ,
  • Wangzhiyuan He,
  • Hao Pan,
  • Liting Fan,
  • Xiaojian Yang,
  • Jinpeng Shi and
  • Shaolong Wan
  • + 5 authors+ 0 author

The selective removal of HCl from industrial HCl/SiF4 mixtures was investigated using a series of alcohol-based and deep eutectic solvents (DESs). Among them, glycerol (GL) exhibited superior selectivity for HCl despite a moderate total capacity. Abs...

(This article belongs to the Section Separation Engineering)
  • Article
  • Open Access
1 Citations
731 Views
13 Pages

Integrated High-Purity Sialic Acid Production Process Using Multi-Stage Membrane Filtration Coupled with Resin Adsorption

  • Xue Yu,
  • Zihan Zhai,
  • Qiangcheng Zeng,
  • Jiajia Chen and ,
  • Jiayi Wang,
  • Wei Zhao,
  • Jinling Liang and
  • Guoxiu Han
  • + 3 authors+ 0 author

This study presents a novel, integrated membrane–resin hybrid platform for the high-efficiency purification of N-acetylneuraminic acid (sialic acid, NANA) from complex microbial fermentation broths. By synergistically combining four sequential...

(This article belongs to the Special Issue Recognition Materials and Separation Applications)
  • Review
  • Open Access
2 Citations
1,624 Views
29 Pages

Mine water treatment remains a long-term challenge due to high suspended solids, wide particle size distributions, and inflow variability, all of which stress solid–liquid separation systems. Hydrocyclones and filtration often fail not from ins...

  • Article
  • Open Access
2 Citations
1,724 Views
22 Pages

Recovery of Phenolic Compounds and Proteins from Spent Coffee Grounds Using Eutectic Solvents

  • Cristiane Nunes da Silva,
  • Camilla Ribeiro Ferreira,
  • Bernardo Dias Ribeiro and
  • Filipe Smith Buarque

Spent coffee grounds (SCGs) are an abundant agro-industrial residue with high potential as a source of phenolic compounds and proteins. This study evaluated the extraction of these value-added fractions using hydrophilic and hydrophobic eutectic solv...

  • Article
  • Open Access
946 Views
13 Pages

Four New Terpenoids from Fufang Yinhua Jiedu Granules and Their Anti-Influenza A Virus Activity

  • Xiu Wang,
  • Xiao-Juan Chen,
  • Qing Sun,
  • Juan Song and ,
  • Hai-Zhen Liang and
  • Bai-Ping Ma
  • + 1 author+ 0 author

Fufang Yinhua Jiedu Granules (FFYHG) is usually applied to treat influenza and the common cold. However, there is no available report concerning the effects of chemical constituents in FFYHG on antiviral activity. In our study, four new terpenoid der...

(This article belongs to the Special Issue Extraction, Purification and Functional Substances of Natural Products and Plants)
  • Article
  • Open Access
1 Citations
1,224 Views
24 Pages

In this work, iron–phosphorus-based composite biochar (FPBC) was prepared by modification with the leachate of spent LiFePO4 batteries. The effects of solution pH, dosage, adsorption time, initial concentration, and temperature on the adsorptio...

(This article belongs to the Special Issue Environmental Functional Materials for Pollutant Separation and Remediation)
  • Article
  • Open Access
1,495 Views
12 Pages

Schinus terebinthifolia Raddi: Compounds Isolated by Countercurrent Chromatography and Biological Activities

  • Mara Junqueira Carneiro,
  • Alexandre Augusto Borghi,
  • Guilherme Perez Pinheiro,
  • Ana Lucia Tasca Gois Ruiz and ,
  • Daniela Mizobutti,
  • Elaine Minatel,
  • Lisieux Santana Juliao,
  • Svetlana Ignatova,
  • Peter Hewitson and
  • Alexandra Christine Helena Frankland Sawaya
  • + 5 authors+ 0 author

The chemical composition of natural products is complex and the investigation of bioactivities of compounds of interest demands their isolation. S. terebinthifolia Raddi is a tree belonging to the Anacardiaceae family and is used in Brazilian folk me...

(This article belongs to the Special Issue Extraction, Purification and Functional Substances of Natural Products and Plants)
  • Article
  • Open Access
759 Views
12 Pages

Experimental Analysis of PEGs Separation at Mono–Channel Ceramic Membranes in DEMO Plasma Exhaust Processing

  • Luca Farina,
  • Gessica Cortese,
  • Daniela Pietrogiacomi,
  • Maria Cristina Campa and
  • Silvano Tosti

Plasma Enhancement Gases (PEGs) are a set of gaseous elements studied for converting plasma thermal energy and mitigating the heat load on the plasma-facing components of a tokamak fusion power plant. In particular, PEG separation is part of the Plas...

(This article belongs to the Special Issue Advanced Separation Membranes in Environmental and Energy Fields)
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Separations - ISSN 2297-8739