2026 September - 56 articles
This study evaluated the effects of misfit type, magnitude, and location on the stress distribution in full-arch screw-retained implant frameworks. A maxillary finite element model with four implants was analyzed under 16 scenarios, characterized by...
Biodegradable polymeric scaffolds incorporating bioactive mineral phases are a promising approach for dentin-pulp tissue engineering. Although poly(lactic-co-glycolic acid) (PLGA) microparticles have been widely used as scaffolds due to their biocomp...
This study investigates the feasibility of fluoride delivery via fluoride-generating nonthermal atmospheric plasma (FNTAP) and its antimicrobial effects on in vitro triple-species oral biofilms. FNTAPs were generated by adding 5 or 10 sccm (standard...
Background: Hydroxylapatite is a biocompatible calcium-phosphate ceramic used in regenerative biomaterials. Calcium hydroxylapatite (CaHA) fillers combine immediate mechanical support with subsequent extracellular matrix remodeling, and their materia...
Evidence regarding tantalum nitride (TaN)-coated gold abutment screws is lacking, and studies on diamond-like carbon (DLC)-coated and anaerobic adhesive-coated abutment screws remain limited. This study evaluated the reverse torque values (RTVs) of a...
Injectable collagen biomaterials are used to modify the dermal extracellular matrix in aged skin; however, whether concentration-dependent rheological differences are associated with distinct fibroblast responses remain unclear. We compared 3% and 6%...
Elevated levels of reactive oxygen species (ROS) and persistent inflammatory responses represent principal impediments to efficacious wound healing, particularly in mechanically dynamic or infected wound environments. Consequently, multifunctional hy...
Background: This exploratory study provided a primarily descriptive comparison of two xenogeneic and two synthetic blocks for mandibular onlay augmentation in rabbits. Methods: Twelve rabbits received bilateral block grafts, providing 24 sites alloca...
Background: Pre-clinical training in endodontics relies heavily on typodont teeth to develop operative skills before patient care, but conventional polymer-based typodonts differ from human teeth in their cutting response, requiring greater force and...
Background: This study investigated the fit accuracy of maxillary complete denture bases (CDBs) fabricated using conventional, fully digital, and two hybrid workflows. Methods: Thirteen edentulous patients each received four maxillary CDBs produced v...
Background: The clinical success of modern dental implants requires a balance between mechanical endurance and aesthetic integration. While titanium alloy (Ti-6Al-4V) provides a reliable load-bearing core, yttria-stabilized tetragonal zirconia (Y-TZP...
The physicochemical properties of buccal films are vital for evaluating their suitability for mucosal applications. By focusing on these properties, researchers can enhance the mechanical functionality and mucoadhesion of the films. This study aimed...
Self-adhesive flowable resin composites have been developed to simplify restorative procedures by eliminating separate adhesive application; however, their gingival sealing to dentin remains a concern. This study assessed the gingival marginal sealin...
Conventional hydrogen peroxide (HP) tooth whitening treatments frequently induce structural deterioration of enamel, necessitating the development of biocompatible and highly efficient alternatives. This in vitro study investigated the application of...
This study aimed to evaluate the micro-shear bond strength (μSBS) of TheraCal PT (TP), Endocem MTA Premixed Heavy (EC), One-Fil Putty (OF), and BC Universal RRM (RM) bonded to a flowable composite resin using two universal adhesives (G-Premio Bond...
The study seeks to develop a multifunctional germanium-enriched nanocomposite coating on titanium and to evaluate its ability to modulate early inflammatory responses while promoting osteogenic differentiation in a dental pulp stem cell (DPSC)-based...
Background/Objectives: Evidence comparing cement- and screw-retained implant-supported restorations remains heterogeneous, particularly in augmented posterior maxillae. This study evaluated the association between definitive retention mode and peri-i...
Background/Aim: Restorative materials in pediatric dentistry are frequently exposed to acidic oral liquid medications, which may alter their surface properties and color. This in vitro study compared the surface roughness, three-dimensional topograph...
Chronic oral and maxillofacial diseases are frequently associated with progressive alveolar bone loss, leading to impaired structural integrity of the jaw and increased risk of implant failure, microbial colonization, and microfracture formation. Cer...
Objective: This study aimed to evaluate the long-term degradation behavior, biostimulatory effects, and biocompatibility of a novel poly-L-lactic acid-block-polyethylene glycol/hyaluronic acid (PLLA–b–PEG/HA) composite filler for soft tis...
Angled abutments and cantilever extensions in bar-supported full-arch implant prostheses may generate bending moments and localized stress concentrations within prosthetic components and peri-implant bone. Implant-supported rehabilitation becomes bio...
Background: Three-dimensional (3D) printing and bioprinting have emerged as transformative technologies in tissue engineering and regenerative medicine. Conventional 3D printing enables the fabrication of complex, customizable scaffolds that mimic th...
Background and Objectives: Magnesium-based biomaterials are increasingly investigated due to their biodegradability, bone-like elastic modulus, and potential osteogenic properties. However, alloy composition may influence degradation behavior and loc...
Background: Injectable bone graft substitutes offer a practical alternative to preformed ceramic scaffolds by adapting to irregular bone defects while preserving osteoconductive properties. This study investigated the in vivo performance of hydroxyap...
The clinical success rate of titanium (Ti) implants is significantly reduced in elderly patients and by implant-associated bacterial infections. Thus, Ti surfaces were modified using sandblasted large-grit alkaline etching (SLA), argon-nonthermal pla...
Patient-specific Ti–6Al–4V fixation systems are increasingly used to stabilise the maxilla following segmental Le Fort I osteotomy; however, the biomechanical responses of complete locking and non-locking patient-specific fixation configu...
Introduction: The clinical translation of biomaterial-based strategies for ear reconstruction remains limited by several challenges, including scaffold design, selection of an optimal cell source, and stability of the new cartilage tissue. Most recen...
Tooth extraction followed by alveolar ridge resorption may compromise the aesthetics and future implant placement, especially in the anterior maxilla. This comparative clinical study assessed the effectiveness of Plasma Rich in Growth Factors (PRGF)...
This study aimed to evaluate bone regeneration in critical-size rat calvarial defects treated with a xenogeneic bone graft alone or combined with autologous platelet concentrates prepared using two distinct centrifugation protocols, one based on hori...
Ultrasound-responsive antibacterial therapies represent a cutting-edge approach to combating implant-associated infections, particularly advantageous because of ultrasound’s non-invasive nature, deep penetration, and ability to target infected...
Bioactive polysaccharides (e.g., fucoidan, β-glucans, and medicinal plant polysaccharides) contain functional groups that interact with drug molecules, and some also retain their own biological activities. Through reversible noncovalent interact...
Background: This study aimed to investigate flow, contact angles and capillary penetration of commercially available endodontic sealers by substrate (human root dentin discs [HRD] and gutta-percha [GP]) and by temperature [room (20 °C), or body (...
(1) Background: Hybrid injectable biomaterials incorporating poly-D,L-lactic acid (PDLLA) and hyaluronic acid (HA) have emerged as an important class of biostimulators in aesthetic medicine, combining immediate soft-tissue augmentation with sustained...
Three-dimensionally (3D)-printed denture teeth are increasingly used in clinical practice; however, their wear resistance and surface hardness may be insufficient for long-term clinical application. Moreover, the effect of post-treatment under elevat...
Objective: To compare radiographic changes following regenerative endodontic procedures in immature permanent teeth with pulp necrosis of traumatic or carious origin. Methods: A retrospective study was conducted in 20 immature permanent teeth from 20...
Hydrogels are hydrated three-dimensional polymeric networks with biomedical potential because they can encapsulate therapeutic agents and provide localised, sustained, or stimulus-responsive drug delivery. Their performance is determined by interacti...
Complex patient-specific bone defects remain difficult to reconstruct because the regenerative capacity of bone is limited and prefabricated implants cannot readily match defect geometry. In this work, methylcellulose-gelatin-hydroxyapatite (MC/GEL/H...
The host immune response plays a central role in determining biomaterial performance, particularly through early macrophage activation dynamics at the tissue–biomaterial interface. This study evaluated the response of THP-1-derived human macrop...
Background: Optimal porosity and surface area of additively manufactured Ti-6Al-4V scaffolds for early human mesenchymal stem cell (hMSC) retention remain unclear, despite their importance in reconstruction of critical-sized bone defects. This study...
This study aimed to evaluate the ability of different categories of direct restorative materials to withstand artificial dentin alterations. A total of 360 human dentin specimens were allocated into 18 groups (n = 20). An ion-releasing bulk-fill resi...
Objectives: Clinical outcomes of peri-implant soft tissue augmentation remain variable, and baseline-associated factors of treatment response are poorly understood. This exploratory study aimed to evaluate baseline-associated patterns of peri-implant...
Background: This study compared four biomaterials after maxillary sinus floor elevation in rabbits, focusing on graft persistence, tissue organization, space maintenance, and Schneiderian membrane response. Methods: Thirteen adult New Zealand White r...
Biodegradation of fused filament fabrication (FFF)-printed poly(lactic acid)/polyhydroxybutyrate (PLA/PHB) structures is governed by complex interactions between material composition, structural design, and degradation environment. Although these fac...
Injectable thermoresponsive hydrogels are useful for localized drug delivery because they can be administered as low-viscosity formulations and then form, or reinforce, therapeutic depots directly at diseased tissue sites. Their common design princip...
Large bone defects remain difficult to treat because current bone substitutes largely restore mechanical integrity without reconstructing the periosteal microenvironment that orchestrates endogenous bone regeneration. Here, we developed a periosteum-...
New titanium alloys for biomedical applications are being developed to avoid the use of aluminum and vanadium, which may raise concerns regarding their long-term biological effects. In this study, the effect of tantalum content on the microstructure,...
This study evaluates the thermal and mechanical behavior of innovative copper–nickel–titanium (CuNiTi) rectangular orthodontic wires featuring rounded edges across two different sizes for clinical applications. Differential scanning calor...
Surface wettability is a critical factor influencing the biological performance of orthopedic Ti implants. The native TiO2 film on Ti undergoes changes in wettability under ultraviolet (UV) irradiation. However, the limited tissue penetration of UV l...
Background: Dentin disinfection plays an important role in prosthodontics, reducing the microbial load, preventing postoperative complications and enhancing the bond strength. This in vitro study aims to evaluate the antimicrobial efficacy of differe...
Background and Objectives: Three-dimensional printing is increasingly used to fabricate dental restorations; however, limited evidence is available on the mechanical performance and fracture behavior of printable resin materials used for endocrown re...
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